Latest & greatest articles for babies

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Top results for babies

121. Timing of introduction of allergenic solids for infants at high risk

Timing of introduction of allergenic solids for infants at high risk Food allergy affects an estimated 2% to 10% of the population, with evidence of increasing prevalence over time. Preventing food allergy has become an important public health goal. Health Canada currently recommends breastfeeding infants exclusively until they are 6 months old, while acknowledging that in individual practice, signs of infant readiness may guide the introduction of complementary foods a few weeks earlier (...) . There is emerging evidence that early food introduction, between 4 to 6 months of age, may have a role in preventing food allergy, particularly for egg and peanut, in high-risk infants. For infants at high risk for allergic disease, it is now recommended that commonly allergenic solids be introduced at around 6 months of age, but not before 4 months of age, and guided by the infant’s developmental readiness for food. Continued breastfeeding should be encouraged and supported because of its

2019 Canadian Paediatric Society

122. Simple febrile seizures in a child. First-choice treatments

of meningitis. Following a febrile seizure in a child, hospital admission for possible lumbar puncture is justified in the following situations: history or examination suggestive of meningitis (including a seizure before the age of 6 months or after the age of 6 years, bulging fontanelle, neck stiffness); ongoing antibiotic treatment , potentially masking the signs of meningitis; infant aged 6 to 12 months , with weak immunity against Haemophilus influenza type b or pneumococcus, especially in the absence (...) Simple febrile seizures in a child. First-choice treatments Prescrire IN ENGLISH - Spotlight ''Simple febrile seizures in a child. First-choice treatments'', 1 February 2019 {1} {1} {1} | | > > > Simple febrile seizures in a child. First-choice treatments Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Simple febrile seizures in a child. First

2019 Prescrire

123. Smaller facemasks for positive pressure ventilation in preterm infants: A randomised trial Full Text available with Trip Pro

Smaller facemasks for positive pressure ventilation in preterm infants: A randomised trial Facial measurements of preterm infants indicate that standard diameter facemasks used during positive pressure ventilation are too large, which may lead to mask leak and compromise resuscitation. We aimed to determine whether the use of a facemask that better complies with the dimensions of preterm faces, compared with a standard facemask, reduces facemask leak.Parallel group, randomised controlled trial (...) . Preterm infants ≤32 weeks' gestation receiving facemask ventilation prior to intubation in the neonatal intensive care unit, and those 28-32+6 weeks' receiving facemask ventilation in the delivery room were eligible. Infants were randomised to receive ventilation via a standard (50mm) (control), or a smaller (35mm or 42mm) diameter facemask (intervention), stratified by gestation (≤26 weeks'; 35mm, 27-32+6; 42mm). The primary outcome was leak between the mask and the infants face.Of 298 eligible

2019 EvidenceUpdates

124. External validation and clinical usefulness of first-trimester prediction models for small- and large-for-gestational-age infants: a prospective cohort study Full Text available with Trip Pro

External validation and clinical usefulness of first-trimester prediction models for small- and large-for-gestational-age infants: a prospective cohort study To assess the external validity of all published first-trimester prediction models based on routinely collected maternal predictors for the risk of small- and large-for-gestational-age (SGA and LGA) infants. Furthermore, the clinical potential of the best-performing models was evaluated.Multicentre prospective cohort.Thirty-six midwifery (...) after recalibration.The clinical relevance of the models is limited because of their moderate predictive performance, and because the definitions of SGA and LGA do not exclude constitutionally small or large infants. As most clinically relevant fetal growth deviations are related to 'vascular' or 'metabolic' factors, models predicting hypertensive disorders and gestational diabetes are likely to be more specific.The clinical relevance of prediction models for the risk of small- and large

2019 EvidenceUpdates

125. Association of Long-term Child Growth and Developmental Outcomes With Metformin vs Insulin Treatment for Gestational Diabetes Full Text available with Trip Pro

infants were linked to their B4SC results. Data were analyzed between January 2017 and May 2018.Pharmacologic treatment for GDM with metformin or insulin, measured using pharmaceutical claims data.Child growth (weight and height) and Strengths and Difficulties Questionnaire (SDQ) scores for behavioral development. All outcomes were derived from the B4SC screening program. Linear and log-binomial regression with inverse probability of treatment weighting was used to estimate the association of child (...) Association of Long-term Child Growth and Developmental Outcomes With Metformin vs Insulin Treatment for Gestational Diabetes Metformin is an emerging option for treating gestational diabetes (GDM). However, because metformin crosses the placenta, patients and clinicians are concerned with its long-term effect on child health.To estimate the association of treating GDM with metformin vs insulin with child growth and development.Population-based cohort study of New Zealand women treated

2019 EvidenceUpdates

126. The Association of Hydrocortisone Dosage on Mortality in Infants Born Extremely Premature (Abstract)

The Association of Hydrocortisone Dosage on Mortality in Infants Born Extremely Premature To characterize common dosing strategies and to investigate the association between hydrocortisone dosage and in-hospital mortality in infants born extremely premature.We performed a retrospective review of a cohort of infants born ≤30 weeks' gestational age from 2010 to 2016 from the Pediatrix Clinical Data Warehouse who received hydrocortisone in the first 14 postnatal days. Infants were divided (...) by initial hydrocortisone dosage (high: >2 mg/kg/d vs low: ≤2 mg/kg/d). Baseline characteristics and medication coexposures were compared and mortality was evaluated in a multivariable analysis.A total of 1427 infants were included, 733 with high dosage (51%) and 694 with low dosage (49%). The groups were similar with regard to baseline characteristics. Infants in the high-dosage group had significantly more exposure to any vasopressors (89% vs 84%, P < .001) and greater mortality (50% vs 23%, P < .001

2019 EvidenceUpdates

127. Mupirocin for Staphylococcus aureus Decolonization of Infants in Neonatal Intensive Care Units Full Text available with Trip Pro

Mupirocin for Staphylococcus aureus Decolonization of Infants in Neonatal Intensive Care Units : media-1vid110.1542/5849573989001PEDS-VA_2018-1565Video Abstract BACKGROUND AND OBJECTIVES: Staphylococcus aureus (SA) is the second leading cause of late-onset sepsis among infants in the NICU. Because colonization of nasal mucosa and/or skin frequently precedes invasive infection, decolonization strategies, such as mupirocin application, have been attempted to prevent clinical infection, but data (...) supporting this approach in infants are limited. We conducted a phase 2 multicenter, open-label, randomized trial to assess the safety and efficacy of intranasal plus topical mupirocin in eradicating SA colonization in critically ill infants.Between April 2014 and May 2016, infants <24 months old in the NICU at 8 study centers underwent serial screening for nasal SA. Colonized infants who met eligibility criteria were randomly assigned to receive 5 days of mupirocin versus no mupirocin to the intranasal

2019 EvidenceUpdates

128. Updated recommendations on first-line and second-line antiretroviral regimens and post-exposure prophylaxis and recommendations on early infant diagnosis of HIV

under national laws: An adult is a person older than 19 years of age. An adolescent is a person aged 10–19 years of age. A child is a person 1–9 years of age. An infant is a child younger than one year of age. A neonate is an infant younger than four weeks of age. Adolescent girls and women of childbearing potential Adolescent girls and women of childbearing potential are defined as premenopausal females capable of becoming pregnant. Nuceloside Reverse Transcriptase Inhibitor (NRTI) Antiretroviral (...) Updated recommendations on first-line and second-line antiretroviral regimens and post-exposure prophylaxis and recommendations on early infant diagnosis of HIV UPDATED RECOMMENDATIONS ON FIRST-LINE AND SECOND-LINE ANTIRETROVIRAL REGIMENS AND POST-EXPOSURE PROPHYLAXIS AND RECOMMENDATIONS ON EARLY INFANT DIAGNOSIS OF HIV SUPPLEMENT TO THE 2016 CONSOLIDATED GUIDELINES ON THE USE OF ANTIRETROVIRAL DRUGS FOR TREATING AND PREVENTING HIV INFECTION DECEMBER 2018 INTERIM GUIDELINES HIV TREATMENTUPDATED

2019 World Health Organisation HIV Guidelines

129. Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial. Full Text available with Trip Pro

for 1 child treated with hydrocortisone. Death or BPD occurred in 128 of 181 infants (70.7%) randomized to hydrocortisone and in 140 of 190 infants (73.7%) randomized to placebo (adjusted risk difference, -3.6% [95% CI, -12.7% to 5.4%]; adjusted odds ratio, 0.87 [95% CI, 0.54-1.38]; P = .54). Of 29 secondary outcomes, 8 showed significant differences, including death at 36 weeks' postmenstrual age (15.5% with hydrocortisone vs 23.7% with placebo; risk difference, -8.2% [95% CI, -16.2% to -0.1 (...) Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial. Dexamethasone initiated after the first week of life reduces the rate of death or bronchopulmonary dysplasia (BPD) but may cause long-term adverse effects in very preterm infants. Hydrocortisone is increasingly used as an alternative, but evidence supporting its efficacy and safety is lacking.To

2019 JAMA Controlled trial quality: predicted high

130. Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial. Full Text available with Trip Pro

Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial. Infections acquired in hospital are an important cause of morbidity and mortality in very preterm infants. Several small trials have suggested that supplementing the enteral diet of very preterm infants with lactoferrin, an antimicrobial protein processed from cow's milk, prevents infections and associated complications. The aim of this large randomised controlled trial was to collect data (...) to enhance the validity and applicability of the evidence from previous trials to inform practice.In this randomised placebo-controlled trial, we recruited very preterm infants born before 32 weeks' gestation in 37 UK hospitals and younger than 72 h at randomisation. Exclusion criteria were presence of a severe congenital anomaly, anticipated enteral fasting for longer than 14 days, or no realistic prospect of survival. Eligible infants were randomly assigned (1:1) to receive either enteral bovine

2019 Lancet Controlled trial quality: predicted high

131. The Effects of Caressing and Hugging Infants to Manage the Pain during Venipuncture. (Abstract)

The Effects of Caressing and Hugging Infants to Manage the Pain during Venipuncture. The aim of this study is to investigate the effects of caressing in infants for pain management during venipuncture. This is a randomized control trial, carried out on 120 infants between 2 and 6 months of age, that included 30 males and 30 females in the hugging and control group, respectively. Parameters such as percentage blood saturation of blood, crying, and the duration of pain felt was evaluated (...) . The venipuncture between the control and experimental groups showed that, less pain is felt by females when caressed by their mother. However, this difference does have statistical significance. Overall, caressing in infants had positive effect on pain-relief after venipuncture.

2019 Comprehensive child and adolescent nursing Controlled trial quality: uncertain

132. A randomized controlled field trial of iBsafe-a novel child safety game app. Full Text available with Trip Pro

A randomized controlled field trial of iBsafe-a novel child safety game app. Injury is a leading cause of child morbidity and mortality worldwide. Delivering injury prevention programs via mobile platforms, such as applications (apps), may reduce risky behaviors. iBsafe is an "interactive Bike and Bite safety" mobile game app founded in behavioral theory and designed to educate kindergarten-aged children about bicycle and dog-related safety. This study assessed the relationship of iBsafe game (...) play and child safety knowledge and skills; hypothesizing that iBsafe increases safety knowledge with translation to practice.This single-blinded, randomized, controlled field trial included sixty 5-6-year-old children. Parent-child dyads were randomly assigned to receive a weeklong field trial of iBsafe or control. Pre- and post-intervention safety knowledge tests were completed; post-intervention safety skills assessments occurred in a simulated safety lab using real props (i.e., safety street

2019 mHealth Controlled trial quality: uncertain

133. Peer Support Increases Maternal Confidence, Kangaroo Mother Care Implementation and Weight Gain in LBW Infants. (Abstract)

Peer Support Increases Maternal Confidence, Kangaroo Mother Care Implementation and Weight Gain in LBW Infants. Weight gain in low birth weight infants can be improved by Kangaroo Mother Care (KMC). The sustainability of KMC implementation can be improved by increasing maternal confidence. Therefore, an appropriate method is needed in KMC education so that maternal confidence, KMC implementation, and weight gain in low birth weight infants can be increased. This study aimed to determine (...) the effect of peer support on maternal self-confidence, KMC implementation, and infant's weight gain in four hospitals: one hospital in Jakarta, Bogor, Tangerang, and Bekasi. The study design was a randomized controlled trial with pre-post test equivalent group which involved 24 participants in both intervention and control group, respectively, based on selected criteria. The intervention provided was three sessions of education on KMC based on individual approach provided by peers. The KMC

2019 Comprehensive child and adolescent nursing Controlled trial quality: uncertain

134. Nesting with Fixation and Position to Facilitate Quiet Sleep and Oxygen Saturation on Low-Birth Weight Infants. (Abstract)

Nesting with Fixation and Position to Facilitate Quiet Sleep and Oxygen Saturation on Low-Birth Weight Infants. Low-birth weight (LBW) infants have a major problem of sleep-awake and instability on physiological function. The objective of this study was to identify the effect of nesting with fixation and position on sleep-awake status and physiological function. This study used a crossover design and was conducted in a general hospital in Jakarta, involving 19 LBW infants who met the inclusion (...) method to facilitate quiet sleep and the stability of SaO2 followed by nesting with fixation combined with quarter prone position as alternative intervention for LBW infant. Therefore, the application of nesting with fixation is needed.

2019 Comprehensive child and adolescent nursing Controlled trial quality: uncertain

135. Maternal and child health: Mothers who give birth to offspring with low birth weight may have increased risk for cardiovascular death

Maternal and child health: Mothers who give birth to offspring with low birth weight may have increased risk for cardiovascular death Mothers who give birth to offspring with low birth weight may have increased risk for cardiovascular death | BMJ Evidence-Based Medicine Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Mothers who give birth to offspring with low birth weight may have increased risk for cardiovascular death Article Text Commentary Maternal and child health Mothers who give birth to offspring with low birth weight may have increased risk for cardiovascular death Anne Eskild 1 , 2 Statistics from Altmetric.com Commentary on : Morken NH, Halland F, DeRoo LA, et

2019 Evidence-Based Medicine

136. Maternal and child health: European Recommendations for good practice in addition to an evidence-based guidelines programme: rationale and method of development

Maternal and child health: European Recommendations for good practice in addition to an evidence-based guidelines programme: rationale and method of development European Recommendations for good practice in addition to an evidence-based guidelines programme: rationale and method of development | BMJ Evidence-Based Medicine Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword (...) Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here European Recommendations for good practice in addition to an evidence-based guidelines programme: rationale and method of development Article Text Research methods and reporting Maternal and child health European Recommendations for good practice in addition to an evidence-based guidelines programme

2019 Evidence-Based Medicine

137. Can child-focused sanitation and nutrition programming improve health practices and outcomes? Evidence from a randomised controlled trial in Kitui County, Kenya. Full Text available with Trip Pro

Can child-focused sanitation and nutrition programming improve health practices and outcomes? Evidence from a randomised controlled trial in Kitui County, Kenya. In Kenya's Kitui County, 46% of children under 5 years are stunted. Sanitation and nutrition programmes have sought to reduce child undernutrition, though they are typically implemented separately. We evaluate the effectiveness of an integrated sanitation and nutrition (SanNut) intervention in improving caregiver sanitation (...) villages only received the CLTS intervention. 8 households with children under 5 years were randomly selected from each evaluation village to participate in the endline survey, for a total of 4322 households.SanNut led to modest improvements in sanitary knowledge and practices emphasised by the programme. Caregivers in treatment villages were 3.3 pp (+32%) more likely to mention lack of handwashing after handling child faeces as a potential cause of diarrhoea, and 4.9 pp (+7.8%) more likely to report

2019 BMJ global health Controlled trial quality: uncertain

138. Influence of infant feeding on the excretion of gluten immunopeptides in feces. (Abstract)

Influence of infant feeding on the excretion of gluten immunopeptides in feces. the secretion of antigens from the diet into breast milk has been extensively documented. The transfer of gliadin could be critical for the development of an immune response.to investigate the presence of immunogenic gluten peptides in the feces of infants fed with different diets.a blind, prospective, controlled, collaborative study was performed in three hospitals, between September 2016 and January 2017 (...) . The study protocol was approved by the Ethics Committee of the hospitals in Seville prior to starting the study.the cohort was divided into three groups of 30 infants: an experimental group (average age 9.2 ± 2.8 weeks) with exclusive breastfeeding, a control group 1 (average age 10.3 ± 3.3 weeks) exclusively fed with onset formula and a control group 2 (average age 56 ± 3.7 weeks) with infants that consumed gluten on a regular basis. The peptide 33-mer of gliadin was negative in all feces samples from

2019 Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva Controlled trial quality: uncertain

139. Suspected Spine Trauma ? Child

, which can result in skin breakdown and ulceration when used over prolonged periods of time [7]. Discussion of Procedures by Variant Variant 1: Child, 3 to 16 years of age, acute cervical spine trauma, meets low risk criteria (based on PECARN or NEXUS). Initial imaging. Radiography Cervical Spine The routine radiograph of the cervical spine in children with head trauma has a very low yield; in fact, the two cases of cervical injury in a cohort of 905 infants (0.02%) were due to an abusive trauma (...) , 2018. 3. Dogan S, Safavi-Abbasi S, Theodore N, et al. Thoracolumbar and sacral spinal injuries in children and adolescents: a review of 89 cases. J Neurosurg 2007;106:426-33. 4. Katz JS, Oluigbo CO, Wilkinson CC, McNatt S, Handler MH. Prevalence of cervical spine injury in infants with head trauma. J Neurosurg Pediatr 2010;5:470-3. 5. Ryan ME, Palasis S, Saigal G, et al. ACR Appropriateness Criteria head trauma--child. J Am Coll Radiol 2014;11:939-47. 6. Madura CJ, Johnston JM, Jr. Classification

2019 American College of Radiology

140. Suspected Appendicitis?Child

Suspected Appendicitis?Child New 2018 ACR Appropriateness Criteria ® 1 Suspected Appendicitis–Child American College of Radiology ACR Appropriateness Criteria ® Suspected Appendicitis–Child Variant 1: Child. Suspected acute appendicitis, low clinical risk. Initial imaging. Procedure Appropriateness Category Relative Radiation Level CT abdomen and pelvis with IV contrast Usually Not Appropriate ?? ?? CT abdomen and pelvis without and with IV contrast Usually Not Appropriate ?? ?? ? CT abdomen (...) and pelvis without IV contrast Usually Not Appropriate ?? ?? MRI abdomen and pelvis without and with IV contrast Usually Not Appropriate O MRI abdomen and pelvis without IV contrast Usually Not Appropriate O US abdomen Usually Not Appropriate O US abdomen RLQ Usually Not Appropriate O US pelvis Usually Not Appropriate O Radiography abdomen Usually Not Appropriate ?? Variant 2: Child. Suspected acute appendicitis, intermediate clinical risk. Initial imaging. Procedure Appropriateness Category Relative

2019 American College of Radiology