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Latest & greatest articles for breast cancer screening
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on breast cancer screening or other clinical topics then use Trip today.
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Invasive breastcancer and breastcancer mortality after ductal carcinoma in situ in women attending for breastscreening in England, 1988-2014: population based observational cohort study. To evaluate the long term risks of invasive breastcancer and death from breastcancer after ductal carcinoma in situ (DCIS) diagnosed through breast screening.Population based observational cohort study.Data from the NHS BreastScreening Programme and the National Cancer Registration and Analysis (...) treatment (mastectomy, radiotherapy for women who had breast conserving surgery, and endocrine treatment in oestrogen receptor positive disease) and those with larger final surgical margins had lower rates of invasive breast cancer.To date, women with DCIS detected by screening have, on average, experienced higher long term risks of invasive breastcancer and death from breastcancer than women in the general population during a period of at least two decades after their diagnosis. More intensive
Continuation of Annual Screening Mammography and BreastCancer Mortality in Women Older Than 70 Years. Randomized trials have shown that initiating breastcancerscreening between ages 50 and 69 years and continuing it for 10 years decreases breastcancer mortality. However, no trials have studied whether or when women can safely stop screening mammography. An estimated 52% of women aged 75 years or older undergo screening mammography in the United States.To estimate the effect of breastcancer (...) screening on breastcancer mortality in Medicare beneficiaries aged 70 to 84 years.Large-scale, population-based, observational study of 2 screening strategies: continuing annual mammography, and stopping screening.U.S. Medicare program, 2000 to 2008.1 058 013 beneficiaries aged 70 to 84 years who had a life expectancy of at least 10 years, had no previous breastcancer diagnosis, and underwent screening mammography.Eight-year breastcancer mortality, incidence, and treatments, plus the positive
Comparison of Abbreviated Breast MRI vs Digital Breast Tomosynthesis for BreastCancer Detection Among Women With Dense Breasts Undergoing Screening. Improved screening methods for women with dense breasts are needed because of their increased risk of breastcancer and of failed early diagnosis by screening mammography.To compare the screening performance of abbreviated breast magnetic resonance imaging (MRI) and digital breast tomosynthesis (DBT) in women with dense breasts.Cross-sectional (...) study with longitudinal follow-up at 48 academic, community hospital, and private practice sites in the United States and Germany, conducted between December 2016 and November 2017 among average-risk women aged 40 to 75 years with heterogeneously dense or extremely dense breasts undergoing routine screening. Follow-up ascertainment of cancer diagnoses was complete through September 12, 2019.All women underwent screening by both DBT and abbreviated breast MRI, performed in randomized order and read
or 42 CommGuideCancerMCIPsycINFO 1. (mass screening or multiphasic screening or screen or screened or screening or "early detection of cancer").mp. 2. ((neoplasm* or ductal breastcarcinoma* or "hereditary breast and ovarian cancer syndrome") and (diagnosis or prevention)).mp. [mp=title, abstract, heading word, table of contents, key concepts, original title, tests & measures] 3. ((adenoma* or neoplasia or cancer* or neoplasm* or tumo?r* or carcinoma* or adenocarcinoma*) and (breast or cervical (...) or screening).ti,ab. or "early detection of cancer"/ 20. (neoplasms/ or breastneoplasms/ or colorectal neoplasms/ or uterine cervical neoplasms/ or carcinoma, ductal, breast/ or "hereditary breast and ovarian cancer syndrome"/ or inflammatory breastneoplasms/ or colonic neoplasms/ or rectal neoplasms/) and (di or pc).fs. 21. ((adenoma* or neoplasia or cancer* or neoplasm* or tumo?r* or carcinoma* or adenocarcinoma*) and (breast or cervical or cervix or colon or colorectal or crc)).ti,ab. 22. 20 or 21 23
BreastCancerScreening and Diagnosis: A Synopsis of the European Breast Guidelines. The European Commission Initiative for BreastCancerScreening and Diagnosis guidelines (European Breast Guidelines) are coordinated by the European Commission's Joint Research Centre. The target audience for the guidelines includes women, health professionals, and policymakers.An international guideline panel of 28 multidisciplinary members, including patients, developed questions and corresponding (...) of the European Breast Guidelines provides recommendations regarding organized screening programs for women aged 40 to 75 years who are at average risk. The recommendations address digital mammography screening and the addition of hand-held ultrasonography, automated breast ultrasonography, or magnetic resonance imaging compared with mammography alone. The recommendations also discuss the frequency of screening and inform decision making for women at average risk who are recalled for suspicious lesions or who
Digital Tomosynthesis for the Screening and Diagnosis of BreastCancer: Diagnostic Accuracy, Cost-Effectiveness, and Guidelines Digital Tomosynthesis for the Screening and Diagnosis of BreastCancer: Diagnostic Accuracy, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Digital Tomosynthesis for the Screening and Diagnosis of BreastCancer: Diagnostic Accuracy, Cost-Effectiveness, and Guidelines Digital Tomosynthesis for the Screening and Diagnosis of BreastCancer (...) for breastcancer diagnosis? What is the comparative clinical effectiveness of synthetic 2D mammography compared with conventional 2D digital mammography obtained with 3D digital tomosynthesis? What is the cost effectiveness of 3D digital tomosynthesis with or without 2D mammography compared with 2D mammography alone for breastcancerscreening or diagnosis? What are the evidence-based guidelines regarding the use of 3D digital tomosynthesis for breastcancerscreening and diagnosis? Key Message Seven
Strategies to Identify Women at High Risk of Advanced BreastCancer During Routine Screening for Discussion of Supplemental Imaging Federal legislation proposes requiring that screening mammography reports to practitioners and women incorporate breast density information and that women with dense breasts discuss supplemental imaging with their practitioner given their increased risk of interval breastcancer. Instead of discussing supplemental imaging with all women with dense breasts, it may (...) be more efficient to identify women at high risk of advanced breastcancer who may benefit most from supplemental imaging.To identify women at high risk of advanced breastcancer to target woman-practitioner discussions about the need for supplemental imaging.This prospective cohort study assessed 638 856 women aged 40 to 74 years who had 1 693 163 screening digital mammograms taken at BreastCancer Surveillance Consortium (BCSC) imaging facilities from January 3, 2005, to December 31, 2014. Data
Two-view digital breast tomosynthesis versus digital mammography in a population-based breastcancerscreening programme (To-Be): a randomised, controlled trial Digital breast tomosynthesis is an advancement of mammography, and has the potential to overcome limitations of standard digital mammography. This study aimed to compare first-generation digital breast tomo-synthesis including two-dimensional (2D) synthetic mammograms versus digital mammography in a population-based screening (...) cancer, stratified by screening technique (ie, digital breast tomosynthesis and digital mammography). A log-binomial regression model was used to estimate the efficacy of digital breast tomosynthesis versus digital mammography, defined as the crude risk ratios (RRs) with 95% CIs for screen-detected breastcancer for women screened during the recruitment period. A per-protocol approach was used in the analyses. This trial is registered at ClinicalTrials.gov, number NCT02835625, and is closed
Screening for BreastCancer in Average-Risk Women: A Guidance Statement From the American College of Physicians. The purpose of this guidance statement is to provide advice to clinicians on breastcancerscreening in average-risk women based on a review of existing guidelines and the evidence they include.This guidance statement is derived from an appraisal of selected guidelines from around the world that address breastcancerscreening, as well as their included evidence. All national (...) is all clinicians, and the target patient population is all asymptomatic women with average risk for breast cancer.In average-risk women aged 40 to 49 years, clinicians should discuss whether to screen for breastcancer with mammography before age 50 years. Discussion should include the potential benefits and harms and a woman's preferences. The potential harms outweigh the benefits in most women aged 40 to 49 years.In average-risk women aged 50 to 74 years, clinicians should offer screening
Accuracy of Self-Report for Cervical and BreastCancerScreening Management Briefs eBrief-no152 -- Accuracy of Self-Report for Cervical and BreastCancerScreening Enter search terms Button to search HSRD ® Inside VA Budget and Performance Inside the News Room National Observances Special Events » » » » » Management Briefs eBrief-no152 -- Accuracy of Self-Report for Cervical and BreastCancerScreening Health Services Research & Development Management eBrief no. 152 » Issue 152 April 2019 (...) The report is a product of the VA/HSR&D Evidence Synthesis Program. Evidence Brief: Accuracy of Self-Report for Cervical and BreastCancerScreening Guideline-based breast and cervical cancerscreening are considered essential health benefits and are fundamental components of high-quality primary care services in the United States. The aim of cancerscreening is to identify cancers in an early stage when treatment is more likely to be effective. Accurate measurement of cancerscreening rates is vital
reviews showed that women aged 39 to 49 years derived the lowest absolute benefit in terms of deaths prevented ( , ) ( ). Observational studies showed larger relative reductions in breastcancer mortality ( ). Evidence from RCTs (fair quality) and observational studies (poor quality) did not show a reduction in the incidence of advanced disease with breastcancerscreening in women aged 39 to 49 years (pooled results from 4 RCTs: relative risk, 0.98 [95% CI, 0.74 to 1.37]) ( ). Screening intervals (...) diagnostic accuracy characteristics regarding cancer detection, false-positive results, recalls, and biopsy rates. Compared with conventional mammography, DBT seems to reduce recall rates and increase cancer detection ( ). The effect of these more sensitive imaging methods on the spectrum of detected disease and associated screening benefits and harms, including overdiagnosis, is not known. Alternative or Adjunctive Tests to Screening Mammography in Women Who Have Dense Breasts Increased breast density
Accuracy of Self-report for Cervical and BreastCancerScreening Enter search terms Button to search HSRD ® Inside VA Budget and Performance Inside the News Room National Observances Special Events » » » » » Evidence Brief: Accuracy of Self-report for Cervical and BreastCancerScreening Health Services Research & Development Evidence Brief: Accuracy of Self-report for Cervical and BreastCancerScreening to the ESP Report RSS feed Prepared by: Evidence Synthesis Program (ESP) Coordinating (...) Center Portland VA Health Care System Portland, OR Mark Helfand, MD, MPH, MS, Director Recommended Citation: Anderson J, Bourne D, Peterson, K, Mackey K. Evidence Brief: Accuracy of Self-report for Cervical and BreastCancerScreening. VA ESP Project #09-199; 2019. Download PDF: , Purpose The ESP Coordinating Center (ESP CC) is responding to a request from the VHA Performance Workgroup for an evidence brief on the accuracy of patient self-report for cervical and breastcancerscreening. Findings from
Recommendations on screening for breastcancer in women 40-74 years of age who are not at increased risk Recommendations on screening for breastcancer in women aged 40–74 years who are not at increased risk for breastcancer | CMAJ Main menu User menu Search Search for this keyword Search for this keyword Guideline Recommendations on screening for breastcancer in women aged 40–74 years who are not at increased risk for breastcancer Scott Klarenbach , Nicki Sims-Jones , Gabriela Lewin (...) POINTS Low-certainty evidence indicates that screening for breastcancer with mammography results in a modest reduction in breastcancer mortality for women aged 40 to 74 years; the absolute benefit is lowest for women younger than 50 years. Screening may lead to overdiagnosis, resulting in unnecessary treatment of cancer that would not have caused harm in a woman’s lifetime and false-positive results that can lead to both physical and psychological consequences; overdiagnosis and false-positives
for breastcancer. In addition, for women with dense breasts, small tumors may be missed on mammography and the sensitivity of screening is diminished. At the time of publication, 35 states had passed laws mandating that breast density be reported in the letters that radiologists send to women with their mammogram results. The mandated language may be challenging for patients to understand, and such reporting may increase worry for women who are told that their risk for breastcancer is higher than (...) Should This Woman With Dense Breasts Receive Supplemental BreastCancerScreening?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center. Breastcancer will develop in 12% of women during their lifetime and is the second leading cause of cancer death among U.S. women. Mammography is the most commonly used tool to screen for breastcancer. Considerable uncertainty exists regarding the age at which to begin screening and the optimal screening interval. Breast density is a risk factor
Knowledge, Beliefs, and Attitudes About BreastCancerScreening in Latin America and the Caribbean: An In-Depth Narrative Review Purpose Breastcancer (BCA) is the most common cancer and leading cause of cancer mortality among women in Latin America and the Caribbean (LAC), and the number of deaths from BCA is expected to continue to increase. Although barriers to care include the physical accessibility of screening resources, personal and cultural barriers must be explored to understand (...) to identify articles. Thirty-five articles were included according to inclusion and exclusion criteria. Results Themes identified in the literature included knowledge about screening procedures and cause of cancer; knowledge sources; catalysts and deterrents for screening, such as family support, family history; social support or taboo, fear, self-neglect, cost, and transportation; and the perception of the screening experience. Conclusion In addition to physical availability of resources and health care
choose to begin biennial screening between the ages of 40 and 49 years. • For women who are at average risk for breastcancer , most of the benefit of mammography results from biennial screening during ages 50 to 74 years. Of all of the age groups, women aged 60 to 69 2016 5. Mammography in combination with breast ultrasonography versus mammography for breastcancerscreening in women at average risk. BACKGROUND: Breastcancer is the most common malignantdisease diagnosed in women worldwide (...) Breastcancerscreening Top results for breastcancerscreening - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might
The Association of Health Literacy with BreastCancer Knowledge, Perception and Screening Behavior The incidence of breastcancer among Iranian women is increasing, and 70% of patients are diagnosed at advanced stages. The current study aimed at evaluating the association of health literacy (HL) with breastcancer knowledge, perception, and screening behavior in women.The current cross- sectional, descriptive study was conducted on 250 women who referred to health centers in Zahedan, Iran. Data (...) ), and with perceived susceptibility.Interventions to enhance breastcancer knowledge and screening should notice the HL of women.
Automated and Clinical Breast Imaging Reporting and Data System Density Measures Predict Risk of Screen-Detected and Interval Cancers. In 30 states, women who have had screening mammography are informed of their breast density on the basis of Breast Imaging Reporting and Data System (BI-RADS) density categories estimated subjectively by radiologists. Variation in these clinical categories across and within radiologists has led to discussion about whether automated BI-RADS density should (...) be reported instead.To determine whether breastcancer risk and detection are similar for automated and clinical BI-RADS density measures.Case-control.San Francisco Mammography Registry and Mayo Clinic.1609 women with screen-detected cancer, 351 women with interval invasive cancer, and 4409 matched control participants.Automated and clinical BI-RADS density assessed on digital mammography at 2 time points from September 2006 to October 2014, interval and screen-detected breastcancer risk, and mammography
A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breastcancer metastasis Tumor cells disseminate early in tumor development making metastasis-prevention strategies difficult. Identifying proteins that promote the outgrowth of disseminated tumor cells may provide opportunities for novel therapeutic strategies. Despite multiple studies demonstrating that the mesenchymal-to-epithelial transition (MET) is critical for metastatic colonization, key regulators (...) that initiate this transition remain unknown. We serially passaged lung metastases from a primary triple negative breastcancer xenograft to the mammary fat pads of recipient mice to enrich for gene expression changes that drive metastasis. An unbiased transcriptomic signature of potential metastatic drivers was generated, and a high throughput gain-of-function screen was performed in vivo to validate candidates. Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified
The overestimation and the inappropriate promotion of the benefits of mammographic screening in breastcancer research and interventions in the Gaza Strip. There has been extensive debate about whether mammographic screening has done more good than harm. Recent reviews showed that women who undergo mammographic screening are more likely to have a tumour that was an overdiagnosis and therefore would not cause them problems. In the Gaza Strip, a strong forum of people advocate an increase (...) women have low survival rates because of the poor availability of mammography. Only three study groups mentioned harmful effects of mammographic screening. All educational materials had clear information on the benefits of mammographic screening but minimal information on its harms.Research in the Gaza Strip overestimated the reduction in breastcancer mortality that can be attributable to mammographic screening, and this would encourage women to undergo screening without knowing that it could harm