Latest & greatest articles for bronchiolitis

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Bronchiolitis

Bronchiolitis is mainly caused by the respiratory syncytial virus (RSV). The virus travels down to the bronchioles in the lungs causing them to become inflamed making it difficult to breath.

Almost every child will be infected with RSV by the time they reach two years. Adults can also contract the virus, typically during winter months.

In mild cases bronchiolitis will clear up without treatment. The virus that causes bronchiolitis travels through tiny droplets of liquid and can be passed through the air or contracted by touching infected surfaces.

Symptoms include: Sore throat, dry cough, blocked nose and aches and pains throughout the body.

Although there is no cure for chronic bronchiolitis research and clinical studies on bronchiolitis suggest that some lifestyle changes can ease symptoms: avoid smoking, eat a healthy diet and maintain regular exercise. In extreme cases steroids can be prescribed to help minimise inflammation.

Read more on medications used to treat bronchiolitis and the causes of the virus.

Top results for bronchiolitis

41. Viral Bronchiolitis in Children. Full Text available with Trip Pro

Viral Bronchiolitis in Children. 26735994 2016 01 19 2016 05 05 1533-4406 374 1 2016 Jan 07 The New England journal of medicine N. Engl. J. Med. Viral Bronchiolitis in Children. 62-72 10.1056/NEJMra1413456 Meissner H Cody HC eng Journal Article Review United States N Engl J Med 0255562 0028-4793 0 Respiratory Syncytial Virus Vaccines AIM IM N Engl J Med. 2016 May 5;374(18):1792-3 27144868 N Engl J Med. 2016 May 5;374(18):1791-2 27144866 N Engl J Med. 2016 May 5;374(18):1791 27144865 N Engl J (...) Med. 2016 May 5;374(18):1792 27144867 N Engl J Med. 2016 May 5;374(18):1793-4 27144864 Asthma etiology Bronchiolitis, Viral complications immunology therapy virology Child, Preschool Humans Infant Respiratory Sounds etiology Respiratory Syncytial Virus Infections immunology therapy Respiratory Syncytial Virus Vaccines Risk Factors 2016 1 7 6 0 2016 1 7 6 0 2016 1 20 6 0 ppublish 26735994 10.1056/NEJMra1413456

2016 NEJM

42. Systematic review with meta analysis: Nebulised hypertonic saline may be less effective than previously reported in reducing hospital length of stay and admission rate in acute bronchiolitis

Systematic review with meta analysis: Nebulised hypertonic saline may be less effective than previously reported in reducing hospital length of stay and admission rate in acute bronchiolitis Nebulised hypertonic saline may be less effective than previously reported in reducing hospital length of stay and admission rate in acute bronchiolitis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings (...) effective than previously reported in reducing hospital length of stay and admission rate in acute bronchiolitis Article Text Therapeutics/Prevention Systematic review with meta analysis Nebulised hypertonic saline may be less effective than previously reported in reducing hospital length of stay and admission rate in acute bronchiolitis Kevin M Overmann 1 , Todd A Florin 1 , 2 Statistics from Altmetric.com Commentary on : Zhang L , Mendoza-Sassi RA , Klassen TP , et al . Nebulized hypertonic saline

2016 Evidence-Based Medicine

43. Do ß-2 Agonists for Acute Bronchitis Provide Any Benefit?

Do ß-2 Agonists for Acute Bronchitis Provide Any Benefit? TAKE-HOME MESSAGE Although there is no evidence to support the use of b-2 agonists in children with acute cough without air?ow restriction, limited evidence suggests that they may bene?t adults with an acute cough and wheezing but their use must be weighed against any adverse effects. Do b-2 Agonists for Acute Bronchitis Provide Any Bene?t? EBEM Commentators Daniel C. Kolinsky, MD Evan S. Schwarz, MD Washington University in St. Louis (...) School of Medicine Division of Emergency Medicine St. Louis, MO Results Therewereatotalof7studiesthat met inclusion criteria, with a total of 552 patients treated in a pri- mary care setting. The overall quality of the included studies per the Grading of Recommendations, Assessment, Development and Evaluations criteria was low to moderate for ef?cacy of b-2 ago- nists in acute cough or acute bronchitis. Because of signi?cant clinical heterogeneity among the trials, there was no overall com- parison

2016 Annals of Emergency Medicine Systematic Review Snapshots

44. Viral quantity and pathological changes in broilers experimentally infected by IRFIBV32 isolate of infectious bronchitis virus Full Text available with Trip Pro

Viral quantity and pathological changes in broilers experimentally infected by IRFIBV32 isolate of infectious bronchitis virus An Iranian isolate of avian infectious bronchitis virus IRFIBV32 was quantified in experimentally infected broilers using real-time reverse transcriptase polymerase chain reaction and histopathological changes was investigated. Thirty-six 3-week-old commercial broilers were inoculated by 10(5) ELD50/0.1 ml of the virus. On the various days post inoculation (dpi

2015 Virusdisease

45. Budesonide/Formoterol for bronchiolitis obliterans after hematopoietic stem cell transplantation (Abstract)

Budesonide/Formoterol for bronchiolitis obliterans after hematopoietic stem cell transplantation Systemic steroids are the standard treatment for bronchiolitis obliterans syndrome (BOS) after allogeneic hematopoietic stem cell transplantation (HSCT) despite their poor efficacy and disabling side effects.To evaluate the effectiveness and tolerance of budesonide/formoterol as an alternative treatment for BOS after HSCT.In this randomized, double-blind, placebo-controlled study, we randomly

2015 EvidenceUpdates Controlled trial quality: predicted high

46. Antibiotics for acute bronchitis. Full Text available with Trip Pro

Antibiotics for acute bronchitis. Are antibiotics associated with improved outcomes in patients with acute bronchitis?Prescribing antibiotics for acute bronchitis was associated with reduced overall and nighttime cough and with an approximately half-day reduction in duration of cough, in days feeling ill, and in days with impaired activities. However, at follow-up, there were no significant differences in patients receiving antibiotics compared with those receiving placebo in overall clinical

2015 JAMA Controlled trial quality: uncertain

47. Bronchiolitis in children: diagnosis and management

Bronchiolitis in children: diagnosis and management Bronchiolitis in children: diagnosis and Bronchiolitis in children: diagnosis and management management NICE guideline Published: 1 June 2015 nice.org.uk/guidance/ng9 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration (...) be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Bronchiolitis in children: diagnosis and management (NG9) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 19Contents Contents Overview 4 Who

2015 National Institute for Health and Clinical Excellence - Clinical Guidelines

48. Randomised controlled trial: The therapeutic value of hypertonic saline in acute bronchiolitis remains unclear Full Text available with Trip Pro

Randomised controlled trial: The therapeutic value of hypertonic saline in acute bronchiolitis remains unclear The therapeutic value of hypertonic saline in acute bronchiolitis remains unclear | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here The therapeutic value of hypertonic saline in acute bronchiolitis remains unclear Article Text Therapeutics/Prevention Randomised controlled trial The therapeutic value of hypertonic saline in acute

2015 Evidence-Based Medicine

49. Randomised controlled trial: Pulse oximetry may lead to unnecessary hospital admissions for infants with bronchiolitis and mild hypoxaemia Full Text available with Trip Pro

Randomised controlled trial: Pulse oximetry may lead to unnecessary hospital admissions for infants with bronchiolitis and mild hypoxaemia Pulse oximetry may lead to unnecessary hospital admissions for infants with bronchiolitis and mild hypoxaemia | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log (...) in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Pulse oximetry may lead to unnecessary hospital admissions for infants with bronchiolitis and mild hypoxaemia Article Text Therapeutics

2015 Evidence-Based Medicine

50. Are Antibiotics Effective in the Treatment of Acute Bronchitis?

Are Antibiotics Effective in the Treatment of Acute Bronchitis? Systematic Review Snapshot TAKE-HOME MESSAGE In patients without underlying lung disease, antibiotics in acute bronchitis appear to decrease cough, but the clinical signi?cance of this decrease is uncertain. Their use should be weighed against the cost and potential adverse effects for treatment of a self-limiting disease. Are Antibiotics Effective in the Treatment of Acute Bronchitis? EBEM Commentators Manpreet Singh, MD (...) versus control (placebo/no treatment) in acute bronchitis. Clinically Improved Cough Night Cough Shorter Mean Cough Duration Reduction in Ill Feeling Days Reduction in Limited Activity Days Adverse Side Effects RR 1.07 RR 0.64 RR 0.67 MD -0.46 days MD -0.64 days MD -0.49 days RR 1.20 0.99 to 1.15* 0.49 to 0.85* 0.54 to 0.83* -0.87 to -0.04* -0.94 to -0.04* -0.94 to -0.04 CI 1.05 to 1.36* NNT 22 NNT 6 NNT 7 NNH 5 NNT, Number needed to treat; MD, mean difference; NNH, number needed to harm. *95% CI

2015 Annals of Emergency Medicine Systematic Review Snapshots

51. Randomised controlled trial: Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis

Randomised controlled trial: Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Nebulised hypertonic saline does not reduce hospital length of stay in acute bronchiolitis Article Text Therapeutics/Prevention Randomised controlled trial Nebulised hypertonic

2015 Evidence-Based Medicine

52. Hyponatremia in Children with Bronchiolitis Admitted to the Pediatric Intensive Care Unit Is Associated with Worse Outcomes

Hyponatremia in Children with Bronchiolitis Admitted to the Pediatric Intensive Care Unit Is Associated with Worse Outcomes PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2014 PedsCCM Evidence-Based Journal Club

53. Bronchiolitis: Recommendations for diagnosis, monitoring and management of children one to 24 months of age

Bronchiolitis: Recommendations for diagnosis, monitoring and management of children one to 24 months of age Bronchiolitis is the most common reason for admission to hospital in the first year of life. There is tremendous variation in the clinical management of this condition across Canada and around the world, including significant use of unnecessary tests and ineffective therapies. This statement pertains to generally healthy children ≤24 months of age with bronchiolitis. The diagnosis (...) of bronchiolitis is based primarily on the history of illness and physical examination findings. Laboratory investigations are generally unhelpful. Bronchiolitis is a self-limiting disease, usually managed with supportive care at home. Groups at high risk for severe disease are described and guidelines for admission to hospital are presented. Evidence for the efficacy of various therapies is discussed and recommendations are made for management. Monitoring requirements and discharge readiness from hospital

2014 Canadian Paediatric Society

54. High flow therapy versus hypertonic saline in bronchiolitis: randomised controlled trial Full Text available with Trip Pro

High flow therapy versus hypertonic saline in bronchiolitis: randomised controlled trial To demonstrate that heated humidified high-flow nasal cannula (HHHFNC) is superior to inhaled hypertonic saline solution (HSS) in improving respiratory distress in moderate bronchiolitis. In addition, it could improve comfort and reduce length of hospital stay (LOS) and admission to Paediatric Intensive Care Unit (PICU).Randomised Clinical Trial from 1 October 2010 to 31 December 2012.Two urban secondary (...) (no PICU available) paediatric hospitalisation units.Hospitalised children aged up to 6 months with moderate acute bronchiolitis (Respiratory Distress Assessment Instrument, RDAI ≥4).Patients were randomised to HHHFNC or HSS. All of them received epinephrine as bronchodilator.Primary outcome was difference in mean Respiratory Assessment Change Score (RACS) between both groups measured in six previously defined consecutive moments. Secondary outcomes were difference in mean comfort scores in this period

2014 EvidenceUpdates Controlled trial quality: predicted high

55. High-flow nasal cannula therapy for infants with bronchiolitis. Full Text available with Trip Pro

High-flow nasal cannula therapy for infants with bronchiolitis. Bronchiolitis is a common lower respiratory tract illness, usually of viral aetiology, affecting infants younger than 24 months of age and is a frequent cause of hospitalisation. It causes airway inflammation, mucus production and mucous plugging, resulting in airway obstruction. Effective pharmacotherapy is lacking and bronchiolitis is a major cause of morbidity and mortality.Conventional treatment consists of supportive therapy (...) in either group required further respiratory support. Five ongoing trials were identified but no data were available in May 2013. We were not able to perform a meta-analysis.There is insufficient evidence to determine the effectiveness of HFNC therapy for treating infants with bronchiolitis. The current evidence in this review is of low quality, from one small study with uncertainty about the estimates of effect and an unclear risk of performance and detection bias. The included study provides some

2014 Cochrane

56. Bronchiolitis

Bronchiolitis Bronchiolitis - Clinical Practice Guideline -- Clinical Recommendation Welcome Search Search Specify your search AAFP.org Patient Care Clinical Practice Guideline Bronchiolitis Diagnosis and Management of Bronchiolitis (Endorsed, December 2014) The guideline, Diagnosis and Management of Bronchiolitis , was developed by the American Academy of Pediatrics and endorsed by the American Academy of Family Physicians. Key Recommendations The diagnosis of bronchiolitis and assessment (...) of disease severity should be based on history and physical examination. Laboratory and radiologic studies should not be routinely ordered for diagnosis. Risk factors for severe disease such as age < 12 weeks, premature birth, underlying cardiopulmonary disease, or immunodeficiency should be assessed when making decisions about evaluation and management of children with bronchiolitis. Bronchodilators (albuterol, salbutamol), epinephrine, and corticosteroids should not be administered to infants

2014 American Academy of Family Physicians

57. Diagnosis and Management of Bronchiolitis Obliterans Syndrome: An Official ATS/ERS/ISHLT Clinical Practice Guideline

Diagnosis and Management of Bronchiolitis Obliterans Syndrome: An Official ATS/ERS/ISHLT Clinical Practice Guideline An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome Keith C. Meyer 1 , Ganesh Raghu 2 , Geert M. Verleden 3 , Paul A. Corris 4 , Paul Aurora 5 , Kevin C. Wilson 6 , Jan Brozek 7 , Allan R. Glanville 8 and the ISHLT/ATS/ERS BOS Task Force Committee 9 Affiliations: 1 School of Medicine and Public Health (...) and their affiliations can be found in the Acknowledgements section. Correspondence: Keith C. Meyer, University of Wisconsin Lung Transplant and Advanced Pulmonary Disease Program, Section of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin, Madison, WI, USA. E-mail: kcm@medicine.wisc.edu ABSTRACT Bronchiolitis obliterans syndrome (BOS) is a major complication of lung transplantation that is associated with poor survival. The International Society for Heart and Lung

2014 American Thoracic Society

58. Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis

Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis | From the American Academy of Pediatrics | Pediatrics '); document.write(''); } function OAS_AD(pos) { if (OAS_version >= 11 && typeof(OAS_RICH)!='undefined') { OAS_RICH(pos); } else { OAS_NORMAL(pos); } } //--> Search for this keyword Source User menu Sections Sign up for highlighting editor-chosen studies (...) with the greatest impact on clinical care. Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis Shawn L. Ralston , Allan S. Lieberthal , H. Cody Meissner , Brian K. Alverson , Jill E. Baley , Anne M. Gadomski , David W. Johnson , Michael J. Light , Nizar F. Maraqa , Eneida A. Mendonca , Kieran J. Phelan , Joseph J. Zorc , Danette Stanko-Lopp , Mark A. Brown , Ian Nathanson , Elizabeth Rosenblum , Stephen Sayles III , Sinsi Hernandez-Cancio This article has a correction. Please

2014 American Academy of Pediatrics

59. An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome

An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome | European Respiratory Society Main menu User menu Search Search for this keyword Search for this keyword An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome Keith C. Meyer , Ganesh (...) Great Ormond Street Hospital for Children , London , UK Kevin C. Wilson Boston University Medical Center , Boston, MA , USA Jan Brozek McMaster University , Hamilton, ON , Canada Allan R. Glanville The Lung Transplant Unit, St Vincents Hospital , Sydney , Australia A full list of the ISHLT/ATS/ERS BOS Task Force Committee members and their affiliations can be found in the Acknowledgements section Abstract Bronchiolitis obliterans syndrome (BOS) is a major complication of lung transplantation

2014 International Society for Heart and Lung Transplantation

60. Effect of oximetry on hospitalization in bronchiolitis: a randomized clinical trial. Full Text available with Trip Pro

Effect of oximetry on hospitalization in bronchiolitis: a randomized clinical trial. Routine use of pulse oximetry has been associated with changes in bronchiolitis management and may have lowered the hospitalization threshold for patients with bronchiolitis.To examine if infants with bronchiolitis whose displayed oximetry measurements have been artificially elevated 3 percentage points above true values experience hospitalization rates at least 15% lower compared with infants with true values (...) displayed.Randomized, double-blind, parallel-group trial conducted from 2008 to 2013 in a tertiary-care pediatric emergency department in Toronto, Ontario, Canada. Participants were 213 otherwise healthy infants aged 4 weeks to 12 months with mild to moderate bronchiolitis and true oxygen saturations of 88% or higher.Pulse oximetry measurements with true saturation values displayed or with altered saturation values displayed that have been increased 3 percentage points above true values.The primary outcome

2014 JAMA Controlled trial quality: predicted high