Latest & greatest articles for bronchiolitis

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This page lists the very latest high quality evidence on bronchiolitis and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Bronchiolitis

Bronchiolitis is mainly caused by the respiratory syncytial virus (RSV). The virus travels down to the bronchioles in the lungs causing them to become inflamed making it difficult to breath.

Almost every child will be infected with RSV by the time they reach two years. Adults can also contract the virus, typically during winter months.

In mild cases bronchiolitis will clear up without treatment. The virus that causes bronchiolitis travels through tiny droplets of liquid and can be passed through the air or contracted by touching infected surfaces.

Symptoms include: Sore throat, dry cough, blocked nose and aches and pains throughout the body.

Although there is no cure for chronic bronchiolitis research and clinical studies on bronchiolitis suggest that some lifestyle changes can ease symptoms: avoid smoking, eat a healthy diet and maintain regular exercise. In extreme cases steroids can be prescribed to help minimise inflammation.

Read more on medications used to treat bronchiolitis and the causes of the virus.

Top results for bronchiolitis

141. Management of bronchiolitis in infants and children

Management of bronchiolitis in infants and children Management of bronchiolitis in infants and children Management of bronchiolitis in infants and children Vishwanathan M, King V J, Bordley C, Honeycutt A A, Wittenborn J, Jackman A M, Sutton S F, Lohr K N CRD summary This review assessed the management (diagnosis, treatment, prophylaxis) of bronchiolitis in infants and children. The authors concluded that there is insufficient evidence to recommend any of the treatment assessed over good (...) supportive care. The authors' conclusions are consistent with the evidence reviewed, and are likely to be robust. Authors' objectives To assess the effectiveness of diagnostic tools, pharmaceutical therapies and prophylactic therapies, and the cost-effectiveness of prophylactic treatment, in the management of bronchiolitis in infants and children. This abstract focused upon the diagnosis and treatment of existing bronchiolitis in infants and children. Searching MEDLINE, the Cochrane Library and HEED were

2003 DARE.

142. Equal effectiveness of older traditional antibiotics and newer broad-spectrum antibiotics in treating patients with acute exacerbations of chronic bronchitis Full Text available with Trip Pro

Equal effectiveness of older traditional antibiotics and newer broad-spectrum antibiotics in treating patients with acute exacerbations of chronic bronchitis Equal effectiveness of older traditional antibiotics and newer broad-spectrum antibiotics in treating patients with acute exacerbations of chronic bronchitis Equal effectiveness of older traditional antibiotics and newer broad-spectrum antibiotics in treating patients with acute exacerbations of chronic bronchitis Peng C C, Aspinall S L (...) , Good C B, Atwood C W, Chang C C Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The study compared the effectiveness and costs of different antibiotic therapies for the treatment of acute exacerbations of chronic bronchitis (AECB

2003 NHS Economic Evaluation Database.

143. A Multicenter, Randomized, Double-Blind, Controlled Trial of Nebulized Epinephrine in Infants with Acute Bronchiolitis.

A Multicenter, Randomized, Double-Blind, Controlled Trial of Nebulized Epinephrine in Infants with Acute Bronchiolitis. PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2003 PedsCCM Evidence-Based Journal Club

144. Clinical bronchiolitis obliterans in workers at a microwave-popcorn plant. Full Text available with Trip Pro

Clinical bronchiolitis obliterans in workers at a microwave-popcorn plant. In May 2000, eight persons who had formerly worked at a microwave-popcorn production plant were reported to have severe bronchiolitis obliterans. No recognized cause was identified in the plant. Therefore, we medically evaluated current employees and assessed their occupational exposures.Questionnaire responses and spirometric findings in participating workers were compared with data from the third National Health (...) of breath, according to comparisons with the national data, and twice the expected rates of physician-diagnosed asthma and chronic bronchitis. Overall, the workers had 3.3 times the expected rate of airway obstruction; those who had never smoked had 10.8 times the expected rate. Workers directly involved in the production of microwave popcorn had higher rates of shortness of breath on exertion and skin problems that had developed since they started work than workers in other parts of the plant

2002 NEJM

145. Reducing antibiotic use for acute bronchitis in primary care: blinded, randomised controlled trial of patient information leaflet. Full Text available with Trip Pro

Reducing antibiotic use for acute bronchitis in primary care: blinded, randomised controlled trial of patient information leaflet. To assess whether sharing the uncertainty of the value of antibiotics for acute bronchitis in the form of written and verbal advice affects the likelihood of patients taking antibiotics.Nested, single blind, randomised controlled trial.Three suburban general practices in Nottingham Participants: 259 previously well adults presenting with acute bronchitis.In group (...) leaflet took antibiotics compared with those who did not receive the leaflet (49 v 63, risk ratio 0.76, 95% confidence interval 0.59 to 0.97, P=0.04). Numbers reconsulting were similar (11 v 14). In group B, 44 patients took the antibiotics.Most previously well adults with acute bronchitis were judged not to need antibiotics. Reassuring these patients and sharing the uncertainty about prescribing in a information leaflet supported by verbal advice is a safe strategy and reduces antibiotic use.

2002 BMJ Controlled trial quality: predicted high

146. Azithromycin for acute bronchitis: a randomised, double-blind, controlled trial. (Abstract)

Azithromycin for acute bronchitis: a randomised, double-blind, controlled trial. The value of azithromycin for treatment of acute bronchitis is unknown, even though this drug is commonly prescribed. We have investigated this question in a randomised, double-blind, controlled trial.Adults diagnosed with acute bronchitis, without evidence of underlying lung disease, were randomly assigned azithromycin (n=112) or vitamin C (n=108) for 5 days (total dose for each 1.5 g). All individuals were also (...) bronchitis. Further studies are needed to identify the best treatment for this disorder.

2002 Lancet Controlled trial quality: predicted high

147. Antibiotic treatment of acute bronchitis in smokers: a systematic review

Antibiotic treatment of acute bronchitis in smokers: a systematic review Antibiotic treatment of acute bronchitis in smokers: a systematic review Antibiotic treatment of acute bronchitis in smokers: a systematic review Linder J A, Sim I Authors' objectives To determine the efficacy of antibiotics for smokers with acute bronchitis. Searching MEDLINE was searched from January 1966 to September 2001 for English language articles. The search terms were reported. The references of retrieved articles (...) were checked for additional studies. Study selection Study designs of evaluations included in the review Randomised placebo-controlled trials were eligible. Specific interventions included in the review Studies of antibiotics were eligible. The antibiotics examined in the included trials were doxycycline, trimethoprim-sulfamethoxazole (TMP-SMX) and erythromycin. Participants included in the review Studies of adults with acute bronchitis, both smokers and nonsmokers, who were previously healthy

2002 DARE.

148. Heliox Therapy in Infants With Acute Bronchiolitis

Heliox Therapy in Infants With Acute Bronchiolitis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2002 PedsCCM Evidence-Based Journal Club

149. A randomized, controlled trial of the effectiveness of nebulized therapy with epinephrine compared with albuterol and saline in infants hospitalized for acute viral bronchiolitis

A randomized, controlled trial of the effectiveness of nebulized therapy with epinephrine compared with albuterol and saline in infants hospitalized for acute viral bronchiolitis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2002 PedsCCM Evidence-Based Journal Club

150. Beta2-agonists for acute bronchitis. (Abstract)

Beta2-agonists for acute bronchitis. The optimal treatment for acute bronchitis is not clear. Because many patients with acute bronchitis have airflow limitation as well as cough, beta2-agonists may be useful.To determine whether beta2-agonists improve the symptoms of acute bronchitis in patients who do not have underlying pulmonary disease.Cochrane Library, MEDLINE, EMBASE, and Conference Proceedings using "bronchodilator (exp)", "adrenergic beta-agonist (exp)", or "sympathomimetics (exp (...) )" and "bronchitis" or "cough"; Science Citation Index for referenced publications; and letters to manufacturers of beta2-agonists.Trials in which patients (adults or children age > 2 years) without known pulmonary disease who were diagnosed with acute bronchitis or acute cough without other cause were randomized to beta2-agonist vs. placebo, no treatment, or alternative treatment.Three reviewers independently first selected outcomes and evaluated trial quality while blinded to study results, and then extracted

2001 Cochrane

151. Place des bronchodilatateurs dans le traitement de la bronchiolite aigue du nourrisson [Role of bronchodilators in the treatment of acute infant bronchiolitis]

Place des bronchodilatateurs dans le traitement de la bronchiolite aigue du nourrisson [Role of bronchodilators in the treatment of acute infant bronchiolitis] Place des bronchodilatateurs dans le traitement de la bronchiolite aigue du nourrisson [Role of bronchodilators in the treatment of acute infant bronchiolitis] Place des bronchodilatateurs dans le traitement de la bronchiolite aigue du nourrisson [Role of bronchodilators in the treatment of acute infant bronchiolitis] Fily A Authors (...) ' objectives To synthesise the evidence on the efficacy of various types of bronchodilators for the treatment of acute bronchiolitis in infants. Searching MEDLINE, HealthSTAR, EMBASE, Pascal and the Cochrane Library were all searched using the keywords 'bronchodilators', 'bronchiolitis' and 'childhood'. Only articles published between 1975 and 2000 in English or French were retained. Study selection Study designs of evaluations included in the review The studies needed to be comparative, prospective

2001 DARE.

152. Bronchodilators for bronchiolitis. Full Text available with Trip Pro

Bronchodilators for bronchiolitis. Bronchiolitis is an acute, highly communicable lower respiratory tract infection. Bronchodilators are commonly used in the management of bronchiolitis in North America, but not in the United Kingdom. The objective of this review was to assess the effects of bronchodilators for bronchiolitis.We searched MEDLINE, EMBASE, Reference Update, reference lists of articles, and the files of two of the authors up to June 1998.Randomised trials comparing bronchodilators

2000 Cochrane

153. Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease. (Abstract)

Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease. Individuals with chronic bronchitis or chronic obstructive pulmonary disease (COPD) may suffer recurrent exacerbations with an increase in volume and/or purulence of sputum and any therapy that reduced the number of exacerbations would be useful. There is a marked difference between countries in terms of the prescribing of mucolytics depending on whether or not they are perceived to be effective.To assess (...) the effects of oral mucolytics in adults with stable chronic bronchitis or COPD.We searched the Cochrane Airways Group trials register and reference lists of articles.Randomised trials that compared oral mucolytic therapy with placebo for at least two months in adults with chronic bronchitis or COPD. Studies of people with asthma and cystic fibrosis were excluded.One reviewer extracted data. Study authors and drug companies were contacted for missing information.Twenty two trials were included. Compared

2000 Cochrane

154. Haemophilus influenzae oral vaccination against acute bronchitis. Full Text available with Trip Pro

Haemophilus influenzae oral vaccination against acute bronchitis. To assess the effects of an oral whole cell nontypeable Haemophilus influenzae (NTHi) vaccine in protecting against recurrent episodes of bronchitis.We searched the Cochrane trials register, MEDLINE, Extramed, ISI Current Contents, Carl Uncover and contacted investigators of the studies.Randomised trials comparing the effects of an oral monobacterial NTHi vaccine on patients with recurrent exacerbations of bronchitis were (...) included when there was overt matching of the vaccine and placebo groups on clinical grounds.Two reviewers extracted data and assessed trial quality independently from original records and publications for incidence and severity of bronchitis episodes and carriage rate of nontypeable Haemophilus influenzae in the upper respiratory tract every three months following vaccination.Six trials were included in the study with a total of 440 participants. Oral vaccination using a monobacterial whole cell

2000 Cochrane

155. Antibiotics for acute bronchitis. Full Text available with Trip Pro

Antibiotics for acute bronchitis. Antibiotic treatment of acute bronchitis, which is one of the most common illnesses seen in primary care, is controversial. Most clinicians prescribe antibiotics in spite of expert recommendations against this practice.People with acute bronchitis may show little evidence of bacterial infection. If effective, antibiotics could shorten the course of the disease. However if they are not effective, the risk of antibiotic resistance may be increased. The objective (...) to 0.79), or to have abnormal lung findings (odds ratio 0.33, 95% confidence interval 0.13 to 0.86), and had a more rapid return to work or usual activities (weighted mean difference 0.7 days earlier, 95% confidence interval 0.2 to 1. 3). Antibiotic-treated patients reported significantly more adverse effects (odds ratio 1.64; 1.05 to 2.57) such as nausea, vomiting, headache, skin rash or vaginitis.Antibiotics appear to have a modest beneficial effect in the treatment of acute bronchitis

2000 Cochrane

156. [A pharmacoeconomic study of the antibiotic treatment of the acute manifestations of chronic bronchitis in primary care]

[A pharmacoeconomic study of the antibiotic treatment of the acute manifestations of chronic bronchitis in primary care] Estudio farmacoeconomico del tratamiento antibiotico de las agudizaciones de la bronquitis cronica en atencion primaria [A pharmacoeconomic study of the antibiotic treatment of the acute manifestations of chronic bronchitis in primary care] Estudio farmacoeconomico del tratamiento antibiotico de las agudizaciones de la bronquitis cronica en atencion primaria (...) [A pharmacoeconomic study of the antibiotic treatment of the acute manifestations of chronic bronchitis in primary care] The DAFNE Group Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of several antibiotic treatments for crises

2000 NHS Economic Evaluation Database.

157. The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review

The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review Stey C, Steurer J, Bachmann S, Medici T C, Tramer M R Authors' objectives To investigate the effect of oral N-acetylcysteine (NAC) in treating chronic bronchitis. Searching The authors searched MEDLINE from 1966 to July (...) 1999, EMBASE from 1982 to July 1999, and the Cochrane Library (Issue 2, 1999) using the free text terms: 'N-acetylcysteine', 'NAC', 'fluimucil' and 'bronchitis', and combinations of these terms. Additional relevant studies were identified by searching the bibliographies of retrieved studies and systematic reviews, and by contacting three manufacturers for in-house databases on NAC and relevant unpublished data. No language restrictions were reported. Study selection Study designs of evaluations

2000 DARE.

158. Systemic corticosteroids in infant bronchiolitis: a meta-analysis

Systemic corticosteroids in infant bronchiolitis: a meta-analysis Systemic corticosteroids in infant bronchiolitis: a meta-analysis Systemic corticosteroids in infant bronchiolitis: a meta-analysis Garrison M M, Christakis D A, Harvey E, Cummings P, Davis R L Authors' objectives To determine whether corticosteroids are efficacious in treating bronchiolitis in hospitalised infants. Searching The following sources were searched: MEDLINE from 1966 to January 1999, the Cochrane Controlled Trials (...) Register (as of January 1999), and EMBASE from January 1990 to January 1999. The search terms included 'bronchiolitis', 'respiratory syncytial viruses', 'adrenal cortex hormones', 'corticosteroid', 'glucocorticoid', 'antiinflammatory agents' and 'steroidal'. The bibliographies of review articles and all selected articles were examined. No language restrictions were reported. Study selection Study designs of evaluations included in the review Randomised placebo-controlled studies. The studies had

2000 DARE.

159. Sustaining the implementation of an evidence-based guideline for bronchiolitis

Sustaining the implementation of an evidence-based guideline for bronchiolitis Sustaining the implementation of an evidence-based guideline for bronchiolitis Sustaining the implementation of an evidence-based guideline for bronchiolitis Perlstein P H, Kotagal U R, Schoettker P J, Atherton H D, Farrell M K, Gerhardt W E, Alfaro M P Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of evidence-based guidelines in the treatment of children with bronchiolitis for a period of more than one year. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study considered infants 1 year old or younger, who were admitted to the hospital with a first-time episode of typical

2000 NHS Economic Evaluation Database.

160. Cost-effectiveness analysis of oral N-acetylcysteine as a preventive treatment in chronic bronchitis Full Text available with Trip Pro

Cost-effectiveness analysis of oral N-acetylcysteine as a preventive treatment in chronic bronchitis Cost-effectiveness analysis of oral N-acetylcysteine as a preventive treatment in chronic bronchitis Cost-effectiveness analysis of oral N-acetylcysteine as a preventive treatment in chronic bronchitis Grandjean E M, Berthet P H, Ruffmann R, Leuenberger P Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains (...) a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Oral N-acetylcysteine (NAC) as a preventive treatment against frequent exacerbations (AECBs) in chronic bronchitis. Type of intervention Primary prevention. Economic study type Cost-effectiveness analysis. Study population The study population consisted of patients with chronic bronchitis. Setting The study setting

2000 NHS Economic Evaluation Database.