Latest & greatest articles for cancer

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on cancer or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on cancer and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for cancer

11181. Benefit of taxanes as adjuvant chemotherapy for early breast cancer: pooled analysis of 15,500 patients Full Text available with Trip Pro

D. Taxanes as primary chemotherapy for early breast cancer: meta-analysis of randomized trials. Cancer 2008;113(2):238-246. Indexing Status Subject indexing assigned by NLM MeSH Antineoplastic Agents, Phytogenic /therapeutic use; Breast Neoplasms /drug therapy /pathology /surgery; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Disease-Free Survival; Female; Humans; Neoplasm Staging; Paclitaxel /therapeutic use; Survival Rate; Taxoids /therapeutic use AccessionNumber 12006002452 (...) chemotherapy for early breast cancer. The authors concluded that paclitaxel and docetaxel significantly improved disease-free survival and overall survival, albeit by a small amount. The results were based on trials involving more than 15,000 patients, but the quality of the review leaves some reservations about the reliability of the conclusions. Authors' objectives The main objective was to quantify the benefit of taxanes as adjuvant chemotherapy for early breast cancer. Searching MEDLINE

2006 DARE.

11182. Meta-analysis of sentinel lymph node biopsy after preoperative chemotherapy in patients with breast cancer

Meta-analysis of sentinel lymph node biopsy after preoperative chemotherapy in patients with breast cancer Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.

11183. 18F-fluoro-deoxyglucose positron emission tomography for post-treatment evaluation of malignant lymphoma: a systematic review

standard test against which the new test was compared No inclusion criteria relating to the reference standard were specified. The authors stated that they used the following criteria to determine whether patients had active disease: tumour positive biopsy or clinico-radiological follow-up of at least 12 months in patients without positive biopsies. The reference tests used in the included studies tended to be histopathology of biopsies in a minority of patients and radiological and clinical follow-up (...) -treatment evaluation of malignant lymphoma: a systematic review. Haematologica 2006; 91(4): 522-529 PubMedID Original Paper URL Indexing Status Subject indexing assigned by NLM MeSH Fluorodeoxyglucose F18; Humans; Lymphoma /diagnosis /therapy; Neoplasm, Residual /diagnosis; Positron-Emission Tomography /standards /statistics & Sensitivity and Specificity; numerical data AccessionNumber 12006003521 Date bibliographic record published 30/11/2007 Date abstract record published 30/11/2007 Record Status

2006 DARE.

11184. Role of sonography in the diagnosis of axillary lymph node metastases in breast cancer: a systematic review

Role of sonography in the diagnosis of axillary lymph node metastases in breast cancer: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.

11185. Chemotherapy in advanced gastric cancer: a systematic review and meta-analysis based on aggregate data Full Text available with Trip Pro

adenocarcinoma of the stomach or gastroesophageal junction were eligible for inclusion. Studies that also included patients with oesophageal or pancreatic cancer were included if sufficient information was available on the subgroup of gastric cancer patients. Outcomes assessed in the review The primary review outcome was overall survival. Treatment-related deaths and quality of life were also assessed in the review. How were decisions on the relevance of primary studies made? Two reviewers independently (...) , Grothey A, Haerting J, Fleig WE. Chemotherapy for advanced gastric cancer. Cochrane Database of Systematic Reviews 2005, Issue 2. Art. No.: CD004064. DOI: 10.1002/14651858.CD004064.pub2. Indexing Status Subject indexing assigned by NLM MeSH Antineoplastic Combined Chemotherapy Protocols /therapeutic use; Humans; Stomach Neoplasms /drug therapy AccessionNumber 12006003681 Date bibliographic record published 31/01/2008 Date abstract record published 31/01/2008 Record Status This is a critical abstract

2006 DARE.

11186. Systematic review: evidence-based management of hepatocellular carcinoma. An updated analysis of randomized controlled trials

Systematic review: evidence-based management of hepatocellular carcinoma. An updated analysis of randomized controlled trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.

11187. Systematic review and meta-analysis of the use of fibrin sealant to prevent seroma formation after breast cancer surgery

Systematic review and meta-analysis of the use of fibrin sealant to prevent seroma formation after breast cancer surgery Systematic review and meta-analysis of the use of fibrin sealant to prevent seroma formation after breast cancer surgery Systematic review and meta-analysis of the use of fibrin sealant to prevent seroma formation after breast cancer surgery Carless P A, Henry D A CRD summary This review investigated the efficacy of fibrin sealants in decreasing the volume of drainage output (...) and rate of seroma formation following breast cancer surgery. The authors concluded that the current evidence does not support the use of fibrin sealant in breast cancer surgery to achieve these outcomes. The authors' conclusions are appropriately cautious given the limitations of the included studies. Authors' objectives To investigate the efficacy of fibrin sealants in decreasing the volume of drainage output and rate of seroma formation following breast cancer surgery. Searching MEDLINE and EMBASE

2006 DARE.

11188. Can intravesical bacillus Calmette-Guerin reduce recurrence in patients with superficial bladder cancer: a meta-analysis of randomized trials

Can intravesical bacillus Calmette-Guerin reduce recurrence in patients with superficial bladder cancer: a meta-analysis of randomized trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.

11189. Clinical and immunologic responses to active specific cancer vaccines in human colorectal cancer

Clinical and immunologic responses to active specific cancer vaccines in human colorectal cancer Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.

11190. Long-term risk of invasive cervical cancer after treatment of squamous cervical intraepithelial neoplasia

of invasive cervical cancer after treatment of squamous cervical intraepithelial neoplasia. International Journal of Cancer 2006; 118(8): 2048-2055 Indexing Status Subject indexing assigned by NLM MeSH Cervical Intraepithelial Neoplasia /complications /therapy; Cohort Studies; Female; Neoplasm Invasiveness; Risk Factors; Time Factors; Uterine Cervical Neoplasms /epidemiology /etiology /pathology; Vaginal Smears AccessionNumber 12006001506 Date bibliographic record published 07/09/2006 Date abstract record (...) Long-term risk of invasive cervical cancer after treatment of squamous cervical intraepithelial neoplasia Long-term risk of invasive cervical cancer after treatment of squamous cervical intraepithelial neoplasia Long-term risk of invasive cervical cancer after treatment of squamous cervical intraepithelial neoplasia Soutter W P, Sasieni P, Panoskaltsis T CRD summary This review determined the occurrence of invasive cancer after treatment for cervical intraepithelial neoplasia (CIN) and the rate

2006 DARE.

11191. Lymphatic mapping and sentinel lymph node biopsy in early-stage breast carcinoma: a metaanalysis

Lymphatic mapping and sentinel lymph node biopsy in early-stage breast carcinoma: a metaanalysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.

11192. Tai chi chuan: mind-body practice or exercise intervention? Studying the benefit for cancer survivors Full Text available with Trip Pro

. Participants included in the review Studies of TCC-naive patients were eligible for inclusion. The primary studies included a variety of patients: elderly people, patients with cardiovascular disease, patients with chronic disease and immunity problems (including osteo- and rheumatoid arthritis, patients with a history of chicken pox, and human immunodeficiency virus), depressed patients, patients with vestibulopathy, postmenopausal women and breast cancer survivors. Outcomes assessed in the review (...) the benefit for cancer survivors. Integrative Cancer Therapies 2006; 5(3): 192-201 PubMedID DOI Indexing Status Subject indexing assigned by NLM MeSH Exercise; Humans; Neoplasms /therapy; Randomized Controlled Trials as Topic; Research Design; Tai Ji; Treatment Outcome AccessionNumber 12006002889 Date bibliographic record published 30/11/2007 Date abstract record published 30/11/2007 Record Status This is a critical abstract of a systematic review that meets the criteria for inclusion on DARE. Each

2006 DARE.

11193. The effects of thyrotropin-suppressive therapy on bone metabolism in patients with well-differentiated thyroid carcinoma Full Text available with Trip Pro

The effects of thyrotropin-suppressive therapy on bone metabolism in patients with well-differentiated thyroid carcinoma The effects of thyrotropin-suppressive therapy on bone metabolism in patients with well-differentiated thyroid carcinoma The effects of thyrotropin-suppressive therapy on bone metabolism in patients with well-differentiated thyroid carcinoma Heemstra K A, Hamdy N A, Romijn J A, Smit J W CRD summary The authors concluded that postmenopausal women taking thyrotropin-suppressive (...) therapy may be at greatest risk of osteoporosis, but studies generally found no increased risk in premenopausal women and men. Poor reporting of review methods, an inadequate quality assessment of the included studies, and the reliance upon studies with small sample sizes make commenting on the reliability of the conclusions difficult. Authors' objectives To evaluate the effects of thyrotropin (TSH)-suppressive thyroxine therapy on bone metabolism in patients with well-differentiated thyroid carcinoma

2006 DARE.

11194. Comparison of endoscopic ultrasound and computed tomography for the preoperative evaluation of pancreatic cancer: a systematic review

Comparison of endoscopic ultrasound and computed tomography for the preoperative evaluation of pancreatic cancer: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.

11195. Malignant ascites: systematic review and guideline for treatment

Malignant ascites: systematic review and guideline for treatment Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.

11196. Cognitive behavioral therapy techniques for distress and pain in breast cancer patients: a meta-analysis

Cognitive behavioral therapy techniques for distress and pain in breast cancer patients: a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.

11197. Meta-analysis of inoperable pancreatic cancer: gemcitabine combined with cisplatin versus gemcitabine alone

Meta-analysis of inoperable pancreatic cancer: gemcitabine combined with cisplatin versus gemcitabine alone Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.

11198. Adjuvant chemotherapy in muscle-invasive bladder carcinoma: a pooled analysis from phase III studies

Adjuvant chemotherapy in muscle-invasive bladder carcinoma: a pooled analysis from phase III studies Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.

11199. Concomitant radio-chemotherapy based on platin compounds in patients with locally advanced non-small cell lung cancer (NSCLC): a meta-analysis of individual data from 1764 patients Full Text available with Trip Pro

; Antineoplastic Agents /adverse effects /therapeutic use; Carcinoma, Non-Small-Cell Lung /drug therapy /radiotherapy; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Lung Neoplasms /drug therapy /radiotherapy; Male; Middle Aged; Platinum Compounds /adverse effects /therapeutic use AccessionNumber 12006001206 Date bibliographic record published 12/04/2007 Date abstract record published 29/07/2009 Record Status This is a critical abstract of a systematic review that meets the criteria (...) Concomitant radio-chemotherapy based on platin compounds in patients with locally advanced non-small cell lung cancer (NSCLC): a meta-analysis of individual data from 1764 patients Concomitant radio-chemotherapy based on platin compounds in patients with locally advanced non-small cell lung cancer (NSCLC): a meta-analysis of individual data from 1764 patients Concomitant radio-chemotherapy based on platin compounds in patients with locally advanced non-small cell lung cancer (NSCLC): a meta

2006 DARE.

11200. Information technology and cancer prevention

and cancer prevention. CA 2006; 56(1): 26-36 PubMedID Original Paper URL Indexing Status Subject indexing assigned by NLM MeSH Humans; Information Services; Medical Audit; Medical Informatics /trends; Medical Records Systems, Computerized /trends; Neoplasms /diagnosis /prevention & Patient Education as Topic; Primary Health Care /standards; Reminder Systems; Telephone; control /therapy AccessionNumber 12006001156 Date bibliographic record published 31/07/2007 Date abstract record published 31/07/2007 (...) Information technology and cancer prevention Information technology and cancer prevention Information technology and cancer prevention Jimbo M, Nease D E, Ruffin M T, Rana G K CRD summary The authors concluded that the impact of information technology on the delivery of cancer preventive services in primary care offices was modest at best, and that further research is required. It is not possible to judge the robustness of these conclusions given the inadequate synthesis of the evidence

2006 DARE.