Latest & greatest articles for cardiac arrest

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Top results for cardiac arrest

181. Cardiac Arrest Emergency Response in Hospitals

Cardiac Arrest Emergency Response in Hospitals Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses should be considered along with other (...) not be copied, posted on a web site, redistributed by email or stored on an electronic system without the prior written permission of CADTH or applicable copyright owner. Links: This report may contain links to other information available on the websites of third parties on the Internet. CADTH does not have control over the content of such sites. Use of third party sites is governed by the owners’ own terms and conditions. TITLE: Cardiac Arrest Emergency Response in Hospitals: Clinical Effectiveness

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

182. Survival After Out-of-Hospital Cardiac Arrest in Relation to Age and Early Identification of Patients With Minimal Chance of Long-Term Survival Full Text available with Trip Pro

Survival After Out-of-Hospital Cardiac Arrest in Relation to Age and Early Identification of Patients With Minimal Chance of Long-Term Survival Survival after out-of-hospital cardiac arrest has increased during the last decade in Denmark. We aimed to study the impact of age on changes in survival and whether it was possible to identify patients with minimal chance of 30-day survival.Using data from the nationwide Danish Cardiac Arrest Registry (2001─2011), we identified 21 480 patients ≥18 (...) years old with a presumed cardiac-caused out-of-hospital cardiac arrest for which resuscitation was attempted. Patients were divided into 3 preselected age-groups: working-age patients 18 to 65 years of age (33.7%), early senior patients 66 to 80 years of age (41.5%), and late senior patients >80 years of age (24.8%). Characteristics in working-age patients, early senior patients, and late senior patients were as follows: witnessed arrest in 53.8%, 51.1%, and 52.1%; bystander cardiopulmonary

2015 EvidenceUpdates

183. Therapeutic hypothermia after out-of-hospital cardiac arrest in children. Full Text available with Trip Pro

Therapeutic hypothermia after out-of-hospital cardiac arrest in children. Therapeutic hypothermia is recommended for comatose adults after witnessed out-of-hospital cardiac arrest, but data about this intervention in children are limited.We conducted this trial of two targeted temperature interventions at 38 children's hospitals involving children who remained unconscious after out-of-hospital cardiac arrest. Within 6 hours after the return of circulation, comatose patients who were older than (...) 2 days and younger than 18 years of age were randomly assigned to therapeutic hypothermia (target temperature, 33.0°C) or therapeutic normothermia (target temperature, 36.8°C). The primary efficacy outcome, survival at 12 months after cardiac arrest with a Vineland Adaptive Behavior Scales, second edition (VABS-II), score of 70 or higher (on a scale from 20 to 160, with higher scores indicating better function), was evaluated among patients with a VABS-II score of at least 70 before cardiac

2015 NEJM Controlled trial quality: predicted high

184. Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised controlled trial. Full Text available with Trip Pro

Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised controlled trial. Mechanical chest compression devices have the potential to help maintain high-quality cardiopulmonary resuscitation (CPR), but despite their increasing use, little evidence exists for their effectiveness. We aimed to study whether the introduction of LUCAS-2 mechanical CPR into front-line emergency response vehicles would improve survival from out (...) -of-hospital cardiac arrest.The pre-hospital randomised assessment of a mechanical compression device in cardiac arrest (PARAMEDIC) trial was a pragmatic, cluster-randomised open-label trial including adults with non-traumatic, out-of-hospital cardiac arrest from four UK Ambulance Services (West Midlands, North East England, Wales, South Central). 91 urban and semi-urban ambulance stations were selected for participation. Clusters were ambulance service vehicles, which were randomly assigned (1:2) to LUCAS

2015 Lancet Controlled trial quality: predicted high

185. Outcome after resuscitation beyond 30 minutes in drowned children with cardiac arrest and hypothermia: Dutch nationwide retrospective cohort study. Full Text available with Trip Pro

Outcome after resuscitation beyond 30 minutes in drowned children with cardiac arrest and hypothermia: Dutch nationwide retrospective cohort study. To evaluate the outcome of drowned children with cardiac arrest and hypothermia, and to determine distinct criteria for termination of cardiopulmonary resuscitation in drowned children with hypothermia and absence of spontaneous circulation.Nationwide retrospective cohort study.Emergency departments and paediatric intensive care units of the eight (...) university medical centres in the Netherlands.Children aged up to 16 with cardiac arrest and hypothermia after drowning, who presented at emergency departments and/or were admitted to intensive care.Survival and neurological outcome one year after the drowning incident. Poor outcome was defined as death or survival in a vegetative state or with severe neurological disability (paediatric cerebral performance category (PCPC) ≥ 4).From 1993 to 2012, 160 children presented with cardiac arrest and hypothermia

2015 BMJ

186. Differences in Vital Signs Between Elderly and Nonelderly Patients Prior to Ward Cardiac Arrest Full Text available with Trip Pro

were also compared. Elderly patients had a higher cardiac arrest rate (2.2 vs 1.0 per 1,000 ward admissions; p<0.001) and in-hospital mortality (2.9% vs 0.7%; p<0.001) than nonelderly patients. Within 4 hours of cardiac arrest, elderly patients had significantly lower mean heart rate (88 vs 99 beats/min; p<0.001), diastolic blood pressure (60 vs 66 mm Hg; p=0.007), shock index (0.82 vs 0.93; p<0.001), and Modified Early Warning Score (2.6 vs 3.3; p<0.001) and higher pulse pressure index (0.45 vs (...) Differences in Vital Signs Between Elderly and Nonelderly Patients Prior to Ward Cardiac Arrest Vital signs and composite scores, such as the Modified Early Warning Score, are used to identify high-risk ward patients and trigger rapid response teams. Although age-related vital sign changes are known to occur, little is known about the differences in vital signs between elderly and nonelderly patients prior to ward cardiac arrest. We aimed to compare the accuracy of vital signs for detecting

2015 EvidenceUpdates

187. Thermogard XP for therapeutic hypothermia after cardiac arrest

with the system range in price from £318.27 to £637.94. The single-use start-up kit is £235.87. A number of consumables, accessories and options are also available. The UK supplier, Delta Surgical, may provide Thermogard XP control units free of charge to the NHS, based on commitment to purchase disposable components. No published evidence on the resource consequences of Thermogard XP was identified. Introduction Introduction Cardiac arrest is caused by a loss of heart function. The heart stops pumping blood (...) around the body, leading to loss of consciousness and death unless emergency resuscitation is given and the heart can be restarted to achieve the return of spontaneous circulation (ROSC). Post-cardiac arrest syndrome can occur after ROSC and involves multiple systems. It reflects a state of whole-body ischaemia (restricted blood supply) and subsequent reperfusion. Its severity depends on the duration and cause of cardiac arrest, often reflecting the underlying condition, pre-existing co-morbidities

2015 National Institute for Health and Clinical Excellence - Advice

188. Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised control trial. Full Text available with Trip Pro

Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised control trial. 28979419 2017 10 05 1751-1437 16 3 2015 Aug Journal of the Intensive Care Society J Intensive Care Soc Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised control trial. 241-243 10.1177/1751143715591402 eng Journal Article Review 2015 06 30 England J Intensive Care Soc 101538668 1751-1437

2015 Journal of the Intensive Care Society Controlled trial quality: uncertain

189. American Heart Association Response to the 2015 Institute of Medicine Report on Strategies to Improve Cardiac Arrest Survival Full Text available with Trip Pro

Resuscitation Quality: Improving Cardiac Resuscitation Outcomes Both Inside and Outside the Hospital” 2013 X X X X “Impact of Percutaneous Coronary Intervention Performance Reporting on Cardiac Resuscitation Centers” 2013 X AHA indicates American Heart Association; CQI, continuous quality improvement; EMS, emergency medical services; and IOM, Institute of Medicine. Table 4. Ongoing AHA Initiatives Related to the 2015 IOM Cardiac Arrest Recommendations IOM Recommendations Ongoing AHA Initiative 1. National (...) closely aligned with the requirements for resuscitation centers for adult nonpregnant cardiac arrest. ACC/AHA indicates American College of Cardiology/American Heart Association; ACLS, advanced cardiac life support; AED, automated external defibrillator; CPR, cardiopulmonary resuscitation; EMS, emergency medical services; EP, electrophysiology; ICD, implantable cardioverter-defibrillator; OHCA, out-of-hospital cardiac arrest; PPCI, primary percutaneous coronary intervention; and STEMI, ST-segment

2015 American Heart Association

190. Epinephrine in Out­?of­?Hospital Cardiac Arrest

Epinephrine in Out­?of­?Hospital Cardiac Arrest Emergency Medicine > Journal Club > Archive > January 2015 Toggle navigation January 2015 Epinephrine in Out-­of­‐Hospital Cardiac Arrest Vignette You are doing an EMS ride­‐along during your EMS elective and get a call for a 70­-year old male in cardiac arrest. The paramedic hits the lights and sirens and you're on scene in five minutes. The fire department has already arrived and CPR is in progress. They tell you that the patient was watching TV (...) a pulse back. On arrival to the ED he has a pulse, is mildly hypotensive, but has no spontaneous breaths and his pupils are fixed and dilated. You know that giving epinephrine in cardiac arrest is the standard of care, but wonder what effect it really has: does it improve ROSC, and if so does it actually improve neurologic function down the road. You wonder if their is really any evidence to support its use at all. You head to the computer and start searching... PICO Question Population: Adult

2015 Washington University Emergency Medicine Journal Club

191. Do Mechanical Devices Improve Return of Spontaneous Circulation Over Manual Chest Compressions in Out-of-Hospital Cardiac Arrest?

, et al. Predictors of survival from out-of-hospital cardiac arrest: a systematic review and meta-analysis. Circ Cardiovasc Qual Outcomes. 2010;3:63-81. 3. Berg RA, Hemphill R, Abella BS, et al. Part 5: adult basic life support: 2010 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2010;122:S685-705. 4. Brooks SC, Bigham BL, Morrison LJ. Mechanical versus manual chest compressions for cardiac arrest. Cochrane Database Syst Rev (...) Do Mechanical Devices Improve Return of Spontaneous Circulation Over Manual Chest Compressions in Out-of-Hospital Cardiac Arrest? Systematic Review Snapshot TAKE-HOME MESSAGE Data are inadequate to determine whether recent devices (either load-distributing band or piston-driven) confer bene?t or harm, though early trial data suggest they do not. Do Mechanical Devices Improve Return of Spontaneous Circulation Over Manual Chest Compressions in Out-of-Hospital Cardiac Arrest? EBEM Commentators

2015 Annals of Emergency Medicine Systematic Review Snapshots

192. Development of a prompt model for predicting neurological outcomes in patients with return of spontaneous circulation from out‐of‐hospital cardiac arrest Full Text available with Trip Pro

Development of a prompt model for predicting neurological outcomes in patients with return of spontaneous circulation from out‐of‐hospital cardiac arrest Early prediction of the neurological outcomes of patients with out-of-hospital cardiac arrest is important to select the optimal clinical management. We hypothesized that clinical data recorded at the site of cardiopulmonary resuscitation would be clinically useful.This retrospective cohort study included patients with return (...) , specificity, and accuracy were 80%, 92%, and 90%, respectively, for the validation dataset (total, n = 201; favourable outcome, n = 25).The 6-month neurological outcomes can be predicted in patients resuscitated from out-of-hospital cardiac arrest using clinical parameters that can be easily recorded at the site of cardiopulmonary resuscitation.

2014 Acute medicine & surgery

193. Propofol administration to the fetal-maternal unit preserved cardiac function in late-preterm lambs subjected to severe prenatal asphyxia and cardiac arrest Full Text available with Trip Pro

Propofol administration to the fetal-maternal unit preserved cardiac function in late-preterm lambs subjected to severe prenatal asphyxia and cardiac arrest 27484022 2016 08 27 2016 08 26 2194-7791 1 Suppl 1 2014 Sep 11 Molecular and cellular pediatrics Mol Cell Pediatr Abstracts of the 50th Workshop for Pediatric Research. A1-A29 eng Journal Article Germany Mol Cell Pediatr 101660689 2194-7791 2016 8 4 6 0 2014 9 11 0 0 2014 9 11 0 1 ppublish 27484022 PMC4715210

2014 Molecular and cellular pediatrics

194. Normothermia versus Therapeutic Hypothermia for Adult Patients after Cardiac Arrest

Normothermia versus Therapeutic Hypothermia for Adult Patients after Cardiac Arrest TITLE: Normothermia versus Therapeutic Hypothermia for Adult Patients after Cardiac Arrest: Clinical Evidence DATE: 26 August 2014 RESEARCH QUESTION What is the clinical evidence for neurological benefits or harms of maintaining normothermia versus induction of therapeutic hypothermia in adult patients following cardiac arrest? KEY FINDINGS Six systematic reviews and one randomized controlled trial were (...) identified regarding the comparative neurological benefits and harms of maintaining normothermia versus induction of therapeutic hypothermia in adult patients following cardiac arrest. METHODS A limited literature search was conducted on key resources including PubMed, The Cochrane Library (2014, Issue 8), University of York Centre for Reviews and Dissemination (CRD) databases, Canadian and major international health technology agencies, as well as a focused Internet search. Methodological filters were

2014 Canadian Agency for Drugs and Technologies in Health - Rapid Review

195. Long-Term Outcomes Following Pediatric Out-of-Hospital Cardiac Arrest

Long-Term Outcomes Following Pediatric Out-of-Hospital Cardiac Arrest PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2014 PedsCCM Evidence-Based Journal Club

196. Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest

Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2014 PedsCCM Evidence-Based Journal Club

197. Early Postresuscitation Hypotension Is Associated With Increased Mortality Following Pediatric Cardiac Arrest

Early Postresuscitation Hypotension Is Associated With Increased Mortality Following Pediatric Cardiac Arrest PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2014 PedsCCM Evidence-Based Journal Club

198. Time to administration of epinephrine and outcome after in-hospital cardiac arrest with non-shockable rhythms: retrospective analysis of large in-hospital data registry. Full Text available with Trip Pro

cardiac arrests (Get With The Guidelines-Resuscitation).We utilized the Get With The Guidelines-Resuscitation database (formerly National Registry of Cardiopulmonary Resuscitation, NRCPR). The database is sponsored by the American Heart Association (AHA) and contains prospective data from 570 American hospitals collected from 1 January 2000 to 19 November 2009.119,978 adults from 570 hospitals who had a cardiac arrest in hospital with asystole (55%) or pulseless electrical activity (45 (...) Time to administration of epinephrine and outcome after in-hospital cardiac arrest with non-shockable rhythms: retrospective analysis of large in-hospital data registry. To determine if earlier administration of epinephrine (adrenaline) in patients with non-shockable cardiac arrest rhythms is associated with increased return of spontaneous circulation, survival, and neurologically intact survival.Post hoc analysis of prospectively collected data in a large multicenter registry of in-hospital

2014 BMJ

199. Vasopressin, steroids, and epinephrine and neurologically favorable survival after in-hospital cardiac arrest: a randomized clinical trial

Vasopressin, steroids, and epinephrine and neurologically favorable survival after in-hospital cardiac arrest: a randomized clinical trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2014 PedsCCM Evidence-Based Journal Club

200. Thrombolytic drugs for cardiac arrest: a review of the clinical effectiveness

: a review of the clinical effectiveness. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response - Summary with Critical Appraisal. 2013 Authors' conclusions Higher quality controlled trials indicate that the use of thrombolytic drugs does not improve survival to hospital discharge and 30-day mortality, and increases the risk of bleeding for patients experiencing a cardiac arrest. Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Heart Arrest (...) Thrombolytic drugs for cardiac arrest: a review of the clinical effectiveness Thrombolytic drugs for cardiac arrest: a review of the clinical effectiveness Thrombolytic drugs for cardiac arrest: a review of the clinical effectiveness CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Thrombolytic drugs for cardiac arrest

2014 Health Technology Assessment (HTA) Database.