Latest & greatest articles for children

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Top results for children

5701. Protective efficacy and safety of three antimalarial regimens for intermittent preventive treatment for malaria in infants: a randomised, double-blind, placebo-controlled trial. (Abstract)

Protective efficacy and safety of three antimalarial regimens for intermittent preventive treatment for malaria in infants: a randomised, double-blind, placebo-controlled trial. Administration of sulfadoxine-pyrimethamine at times of vaccination-intermittent preventive treatment in infants (IPTi)-is a promising strategy to prevent malaria. However, rising resistance to this combination is a concern. We investigated a shortacting and longacting antimalarial drug as alternative regimens (...) for IPTi.We undertook a double-blind, placebo-controlled trial of IPTi in an area of high resistance to sulfadoxine-pyrimethamine at sites of moderate (n=1280 infants enrolled) and low (n=1139) intensity of malaria transmission in Tanzania. Infants aged 8-16 weeks were randomly assigned in blocks of 16 to sulfadoxine (250 mg) plus pyrimethamine (12.5 mg; n=319 in moderate-transmission and 283 in low-transmission sites), chlorproguanil (15 mg) plus dapsone (18.75 mg; n=317 and 285), mefloquine (125 mg; n

2009 Lancet Controlled trial quality: predicted high

5702. 10-year effect of Oportunidades, Mexico's conditional cash transfer programme, on child growth, cognition, language, and behaviour: a longitudinal follow-up study. (Abstract)

10-year effect of Oportunidades, Mexico's conditional cash transfer programme, on child growth, cognition, language, and behaviour: a longitudinal follow-up study. Mexico's conditional cash transfer programme, Oportunidades, was started to improve the lives of poor families through interventions in health, nutrition, and education. We investigated the effect of Oportunidades on children almost 10 years after the programme began.From April, 1998, to October, 1999, low-income communities were (...) -1.14 [0.97]; p=0.88), BMI-for-age Z scores (0.14 [0.99] vs 0.17 [1.06]; p=0.58), or assessment scores for language (98.8 [13.8] vs 98.4 [14.6] p=0.90) or cognition (98.8 [12.9] vs 100.2 [13.2]; p=0.26). An additional 18 months of the programme before age 3 years for children aged 8-10 years whose mothers had no education resulted in improved child growth of about 1.5 cm assessed as height-for-age [corrected] Z score (beta 0.23 [0.023-0.44] p=0.029), independently of cash received.An additional 18

2009 Lancet Controlled trial quality: uncertain

5703. Topical intranasal corticosteroids in 4-11 year old children with persistent bilateral otitis media with effusion in primary care: double blind randomised placebo controlled trial. Full Text available with Trip Pro

Topical intranasal corticosteroids in 4-11 year old children with persistent bilateral otitis media with effusion in primary care: double blind randomised placebo controlled trial. To determine the clinical effectiveness of topical intranasal corticosteroids in children with bilateral otitis media with effusion.Double blind randomised placebo controlled trial.76 Medical Research Council General Practice Research Framework practices throughout the United Kingdom, between 2004 and 2007.217 (...) children aged 4-11 years who had at least one practice recorded episode of otitis media or a related ear problem in the previous 12 months, and with bilateral otitis media with effusion confirmed by a research nurse using otoscopy plus micro-tympanometry (B/B or B/C2, modified Jerger types).Mometasone furoate 50 microg or placebo spray given once daily into each nostril for three months.Proportions of children cured of bilateral otitis media with effusion assessed with tympanometry (C1 or A type

2009 BMJ Controlled trial quality: predicted high

5704. Effect of mass distribution of azithromycin for trachoma control on overall mortality in Ethiopian children: a randomized trial. Full Text available with Trip Pro

Effect of mass distribution of azithromycin for trachoma control on overall mortality in Ethiopian children: a randomized trial. Mass oral azithromycin distribution to affected communities is a cornerstone of the World Health Organization's trachoma elimination program. Antibiotics are provided to target the ocular strains of chlamydia that cause trachoma, but may also be efficacious against respiratory disease, diarrhea, and malaria--frequent causes of childhood mortality in trachoma-endemic (...) years exceeded 80% at all visits.The main outcome measure was the community-specific mortality risk for children aged 1 to 9 years over the course of 1 year. Mortality was measured by enumerative census at baseline and again after 1 year. Comparison of the risk of mortality was a prespecified outcome for the clinical trial.The odds ratio for childhood mortality in the intervention communities was 0.51 (95% confidence interval, 0.29-0.90; P = .02; clustered logistic regression) compared

2009 JAMA Controlled trial quality: uncertain

5705. Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials. (Abstract)

Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials. Although fever is part of the normal inflammatory process after immunisation, prophylactic antipyretic drugs are sometimes recommended to allay concerns of high fever and febrile convulsion. We assessed the effect of prophylactic administration of paracetamol at vaccination on infant febrile reaction rates and vaccine (...) responses.In two consecutive (primary and booster) randomised, controlled, open-label vaccination studies, 459 healthy infants were enrolled from ten centres in the Czech Republic. Infants were randomly assigned with a computer-generated randomisation list to receive three prophylactic paracetamol doses every 6-8 h in the first 24 h (n=226) or no prophylactic paracetamol (n=233) after each vaccination with a ten-valent pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV

2009 Lancet Controlled trial quality: uncertain

5706. Effect of using an interactive booklet about childhood respiratory tract infections in primary care consultations on reconsulting and antibiotic prescribing: a cluster randomised controlled trial. Full Text available with Trip Pro

Effect of using an interactive booklet about childhood respiratory tract infections in primary care consultations on reconsulting and antibiotic prescribing: a cluster randomised controlled trial. To establish whether an interactive booklet on respiratory tract infections in children reduces reconsultation for the same illness episode, reduces antibiotic use, and affects future consulting intentions, while maintaining parental satisfaction with care.Pragmatic cluster randomised controlled trial (...) .61 general practices in Wales and England.558 children (6 months to 14 years) presenting to primary care with an acute respiratory tract infection (7 days or less). Children with suspected pneumonia, asthma or a serious concomitant illness, or needing immediate hospital admission were excluded. Three withdrew and 27 were lost to follow-up, leaving 528 (94.6%) with main outcome data.Clinicians in the intervention group were trained in the use of an interactive booklet on respiratory tract

2009 BMJ Controlled trial quality: predicted high

5707. Effectiveness of quinine versus artemether-lumefantrine for treating uncomplicated falciparum malaria in Ugandan children: randomised trial. Full Text available with Trip Pro

Effectiveness of quinine versus artemether-lumefantrine for treating uncomplicated falciparum malaria in Ugandan children: randomised trial. To compare the effectiveness of oral quinine with that of artemether-lumefantrine in treating uncomplicated malaria in children.Randomised, open label effectiveness study.Outpatient clinic of Uganda's national referral hospital in Kampala.175 children aged 6 to 59 months with uncomplicated malaria.Participants were randomised to receive oral quinine (...) groups.The effectiveness of a seven day course of quinine for the treatment of uncomplicated malaria in Ugandan children was significantly lower than that of artemether-lumefantrine. These findings question the advisability of the recommendation for quinine therapy for uncomplicated malaria in Africa.ClinicalTrials.gov NCT00540202.

2009 BMJ Controlled trial quality: predicted high

5708. Review: high-quality evidence on the effectiveness of laxatives for functional constipation in children is limited

Review: high-quality evidence on the effectiveness of laxatives for functional constipation in children is limited Review: high-quality evidence on the effectiveness of laxatives for functional constipation in children is limitedCommentary | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: high-quality evidence on the effectiveness of laxatives for functional constipation in children is limitedCommentary Article Text Treatment Review

2009 Evidence-Based Nursing

5709. Review: culture-specific programmes improve some asthma-related outcomes in children and adults from ethnic minority groups

Review: culture-specific programmes improve some asthma-related outcomes in children and adults from ethnic minority groups Review: culture-specific programmes improve some asthma-related outcomes in children and adults from ethnic minority groupsCommentary | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log (...) in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: culture-specific programmes improve some asthma-related outcomes in children and adults from ethnic minority groupsCommentary

2009 Evidence-Based Nursing

5710. Review: inhaled corticosteroids reduce wheezing and asthma exacerbations in infants and preschool children

Review: inhaled corticosteroids reduce wheezing and asthma exacerbations in infants and preschool children Review: inhaled corticosteroids reduce wheezing and asthma exacerbations in infants and preschool childrenCommentary | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password (...) wheezing and asthma exacerbations in infants and preschool children Commentary Statistics from Altmetric.com Question Do inhaled corticosteroids (ICSs) reduce wheezing/asthma exacerbations (WAEs) in infants and preschool children with a previous diagnosis of wheezing or asthma? Review scope Included studies were randomised controlled trials (RCTs) of ⩾4 weeks of treatment that compared an ICS with placebo in infants and children ⩽5 years of age with a diagnosis of wheezing or asthma for ⩾6 months

2009 Evidence-Based Nursing

5711. Review: antenatal magnesium sulphate prevents cerebral palsy in preterm infants

Review: antenatal magnesium sulphate prevents cerebral palsy in preterm infants Review: antenatal magnesium sulphate prevents cerebral palsy in preterm infants | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional (...) accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: antenatal magnesium sulphate prevents cerebral palsy in preterm infants Article Text Therapeutics Review: antenatal magnesium sulphate prevents cerebral palsy in preterm infants Statistics from Altmetric.com Question

2009 Evidence-Based Medicine

5712. Economic evaluation of varicella vaccination in Swiss children and adolescents

Economic evaluation of varicella vaccination in Swiss children and adolescents Economic evaluation of varicella vaccination in Swiss children and adolescents Economic evaluation of varicella vaccination in Swiss children and adolescents Banz K, Iseli A, Aebi C, Brunner M, Schmutz AM, Heininger U Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions (...) of children, aged 11 to 15 years, who had no history or an uncertain history of chickenpox; universal vaccination of susceptible children aged one to two years; and both these strategies, with universal vaccination of one-to-two-year-olds and catch-up vaccination of 11-to-15-year-olds, who had no or an uncertain history of chickenpox. Two doses of the vaccine were given. Location/setting Switzerland/primary care. Methods Analytical approach: The authors used a decision-analytic model that had been

2009 NHS Economic Evaluation Database.

5713. Multiple antipsychotic use associated with metabolic and cardiovascular adverse events in children and adolescents

Multiple antipsychotic use associated with metabolic and cardiovascular adverse events in children and adolescents Multiple antipsychotic use associated with metabolic and cardiovascular adverse events in children and adolescents | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Multiple antipsychotic use associated with metabolic and cardiovascular adverse events in children and adolescents Article Text Aetiology Multiple antipsychotic use

2009 Evidence-Based Mental Health

5714. Schizophrenia in either parent increases risk of infant mortality

Schizophrenia in either parent increases risk of infant mortality Schizophrenia in either parent increases risk of infant mortality | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password (...) * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Schizophrenia in either parent increases risk of infant mortality Article Text Aetiology Schizophrenia in either parent increases risk of infant mortality Statistics from Altmetric.com QUESTION Question: Is schizophrenia in either parent associated

2009 Evidence-Based Mental Health

5715. Short term CBT and sertraline, alone or in combination, reduce anxiety in children and adolescents

Short term CBT and sertraline, alone or in combination, reduce anxiety in children and adolescents Short term CBT and sertraline, alone or in combination, reduce anxiety in children and adolescents | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Short term CBT and sertraline, alone or in combination, reduce anxiety in children and adolescents Article Text Therapeutics Short term CBT and sertraline, alone or in combination, reduce

2009 Evidence-Based Mental Health

5716. Child bipolar I disorder is associated with manic episodes in adulthood

. Setting: University medical school research unit, USA; enrolment September 1995 to December 1998. Prognostic factors: Age, gender, illness characteristics and comorbidity (age at onset, CGAS score, psychosis, grandiose delusions, daily cycling, major depressive disorder, dysthymia, attention deficit/hyperactivity disorder, conduct disorder), referring centre (paediatric or psychiatric), parental warmth and tension/hostility (Psychosocial Schedule for School Age Children-Revised) and select mental (...) Child bipolar I disorder is associated with manic episodes in adulthood Child bipolar I disorder is associated with manic episodes in adulthood | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username

2009 Evidence-Based Mental Health

5717. Harsh parenting, insufficient income and infant aggression predict preschool peer victimisation

victimisation Statistics from Altmetric.com QUESTION Question: What are the trajectories of peer victimisation in preschool and what are the predictors of these trajectories? Population: 1970 children (49% female) born in Quebec between October 1997 and July 1998, who were taking part in the Quebec Longitudinal Study of Child Development, selected by stratified sampling from the Quebec Birth Registry. Participants were assessed at average ages of 4.5 and 16.6 months, and 2.4, 3.4, 4.1, 5.1, 6.2 and 7.2 (...) Harsh parenting, insufficient income and infant aggression predict preschool peer victimisation Harsh parenting, insufficient income and infant aggression predict preschool peer victimisation | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts

2009 Evidence-Based Mental Health

5718. The role of antileukotrienes in children

The role of antileukotrienes in children Volumen 17. DTB Navarre. Vol 17, No 1. January - February 2009 - navarra.es Castellano | Euskara | Français | English Use the search tool! Search engine : : : : : : DTB Navarre. Vol 17, No 1. January - February 2009 DTB Navarre. Vol 17, No 1. January - February 2009 Content tools Share it The role of antileukotrienes in children The only therapeutic indication of antileukotrienes is in the management of asthma. In persistent asthma randomized controlled

2009 Drug and Therapeutics Bulletin of Navarre (Spain)

5719. Children?s views about obesity, body size, shape and weight: a systematic review

Children?s views about obesity, body size, shape and weight: a systematic review Obesity - children's views 09 April 2019 Links Download report (pdf) Children’s views about obesity, body size, shape and weight: a systematic review What do we want to know? There are high levels of concern about obesity in children in the UK. Children are likely to experience immediate physical and psychosocial problems as a result of being obese and are at a higher risk of obesity as they grow older. Children’s (...) attitudes to and beliefs about their bodies, which can include high levels of body dissatisfaction, have also raised concern. This systematic review examines recent research findings from the UK where children aged from four to eleven provide views about their own body sizes or about the body sizes of others. Who wants to know? This review will inform policy-makers, commissioners, practitioners, and researchers who have a remit to explore policy issues or to promote or conduct research on children

2009 EPPI Centre

5720. No evidence on best filling material for the treatment of caries in primary teeth in children

No studies were found that compared restorations versus extractions or no treatment as an intervention in children with childhood caries. The study periods ranged from 6 months to 3 years. Context Childhood caries (tooth decay) consists of a form of tooth decay that affects the milk teeth (also known as baby or primary teeth). This may range from tooth decay in a single tooth to rampant caries, affecting all the teeth in the mouth. Primary teeth in young children are vital to their development and every (...) No evidence on best filling material for the treatment of caries in primary teeth in children PEARLS Practical Evidence About Real Life Situations PEARLS are succinct summaries of Cochrane Systematic Reviews for primary care practitioners. They No evidence on best filling material for the treatment of caries in primary teeth in children Clinical question What are the most effective filling materials for the treatment of dental caries in primary teeth in children? Bottom line There were

2009 Cochrane PEARLS