Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4)
Latest & greatest articles for children
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on children or other clinical topics then use Trip today.
This page lists the very latest high quality evidence on children and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.
What is Trip?
Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.
Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.
As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.
For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via email@example.com
Consensus guidelines for managing the airway in children with COVID-19 1 Consensus guidelines for managing the airway in children with COVID-19; Highlighting differences in practice from adult guidelines Guidelines from the Association of Anaesthetists, the Difficult Airway Society, the Intensive Care Society, the Faculty of Intensive Care Medicine and the Royal College of Anaesthetists, Paediatric Intensive Care Society, Association of Paediatric Anaesthetists T. M. Cook, 1 K. El-Boghdadly, 2 (...) Lothian, Edinburgh, UK 5 Consultant, Department of Anaesthesia, Royal National Throat Nose and Ear Hospital and University College London Hospitals NHS Foundation Trust, London, UK 6 Consultant, Department of Anaesthesia and Intensive Care Medicine, Warrington and Halton NHS Foundation Trust, Warrington, UK 7 Consultant, Paediatric Intensive Care, Bristol Royal Hospital for Children, UK 8 Children’s Acute Transport Service (CATS), Great Ormond Street Hospital, UK 9 Consultant, Paediatric Intensive
prone to severe disease compared with older children: 10.6% of infants less than a year old presented with severe or critical illness, compared with 7.3% of children aged 1 to 5, 4.2% (in children aged 6 to 10), 4.1% (in the 11 to 15 age group), and 3.0%, in adolescents 16 years and older. One 14-year-old child in this cohort died [ ] . Another cohort of 171 children from Wuhan with virologically confirmed infection reported that 15.8% had neither symptoms nor radiological abnormalities (...) features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395(10223):497-506. Li W, Cui H, Li K, Fang Y, Li S. Chest computed tomography in children with COVID-19 respiratory infection. Pediatr Radiol 2020: online ahead of print: DOI: 10.1007/s00247-020-04656-7. Rieder M, Jong G, Salvadori M; Canadian Paediatric Society, Drug Therapy and Hazardous Substances Committee. Can NSAIDS be used in children when COVID-19 is suspected?:www.cps.ca/en/documents/position/can-nsaids
the sedating doctor is satisfied that vital signs are within normal limits for that child 14. Recovery should be complete between 60 and 120 minutes, depending on the dose used. The child can be safely discharged once they are at pre- sedation levels: • Conscious and responding appropriately • Nystagmus resolved • Able to walk unassisted (older children) • Vital signs are within normal limits • Respiratory status not compromised • Pain and discomfort addressed 15. An advice sheet (see example, appendix 3 (...) ) should be given to the parent or guardian advising rest and quiet, supervised activity for the remainder of that day. The child should not eat or drink for two hours after discharge because of the risk of nausea and vomiting. The risk of ataxia may persist and lead to an increased risk of falls (in older children they should not drive for at least 24 hours). Ketamine Procedural Sedation for Children in The Emergency Department (Feb 2020) 15 16. The medical record and local audit documentation should
Paediatric Trauma: Stabilisation of the Cervical Spine Patron: HRH The Princess Royal 7-9 Bream’s Buildings Tel +44 (0)207 404 1999 London Fax +44 (0)207 067 1267 EC4A 1DT www.rcem.ac.uk Position Statement Paediatric Trauma - Stabilisation of the Cervical Spine 10 April 2019 The Royal College of Emergency Medicine (RCEM) recognises that there are nationwide discrepancies in how immobilisation of the cervical spine is achieved during the initial assessment of children who have suffered traumatic (...) and prolonged immobilisation. - Raising the intracranial pressure in children with traumatic brain injury (although the studies all involve small numbers of adults and show only small rises in pressure which may not be clinically significant). The lack of evidence of benefit and concerns surrounding potential harm have led the Advanced Paediatric Life Support Group , Resuscitation Council UK  and International Liaison Committee On Resuscitation (ILCOR)  to recommend that semi
– paediatric cubicle ** Parent – with child. Level 1 Level 1 Child – paediatric cubicle ** Parent – adult ward ** Note this may alter over time – local decisions to collocate parent and child may be necessary Level 1 Level 2/3 Child – paediatric cubicle ** If necessary need to plan locally for a child without available carer Parent - adult ward ** Escalate to HDU/ITU as per usual pathway Level 2/3 Well* Child – paeds ward cubicle ** Transfer to PICU as per usual pathway if deteriorates Parent – home (...) COVID-19 - Isolation plans for parent-child combinations COVID-19 - Isolation plans for parent-child combinations | RCPCH Quick links Quick links Search RCPCH Search X Search RCPCH Search Submenu membership Submenu education Submenu work we do Submenu resources Submenu key topics Submenu news and events Quick links Quick links Submenu membership Submenu education Submenu work we do Submenu resources Submenu key topics Submenu news and events X COVID-19 - Isolation plans for parent-child
groups of children as inpatients. It also advises on specific groups of children - those with febrile neutropenia, and those at increased risk of COVID-19. Last modified 8 April 2020 Post date 8 April 2020 Table of contents Contents Suspected child – mildly-moderately symptomatic requiring admission (level 0–1) Level 0 is a standard ward paediatric patient. Level 1 refers to level 1 paediatric critical care. Children with mild to moderate symptoms and are admitted for observation/feeding support (...) chlorine clean following discharge if screening results pending or confirmed positive. Suspected child – requiring PICU level 3 care The Paediatric Intensive Care Society (PICS) have put together specific to the management of critically ill children, including flow diagrams for suspected and confirmed cases of COVID-19 infection Details regarding the . Level 3 care includes intubation and ongoing ventilation. Management and referral pathways for level 2 and 3 patients are described in PICs guidance
Details This guidance covers children: supported by the child social care system with education, health and care ( 1 April 2020 Updated guidance on educational provision over the Easter holidays. 27 March 2020 Updated the following sections of the guidance: 13, 20, 21, 22, 24, 26, 27 and 30. 25 March 2020 Updated guidance to include additional information on children with education health and care (EHC) plans and children in alternative provision (AP) settings. 22 March 2020 First published. Related (...) Coronavirus (COVID-19): guidance on vulnerable children and young people Coronavirus (COVID-19): guidance on vulnerable children and young people - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Stay at home Only go outside for food, health reasons or work (but only if you cannot work
Paediatric emergency care during the COVID-19 pandemic Paediatric emergency care during the COVID-19 pandemic | CHQ Children’s Health Queensland Hospital and Health Service > > Paediatric emergency care during the COVID-19 pandemic Paediatric emergency care during the COVID-19 pandemic For the latest available information to assist Queensland clinicians to diagnose and/or treat patients with suspected or confirmed COVID-19 (novel coronavirus) refer to the website. This page contains information (...) specific to the emergency care of children during the COVID-19 outbreak: COVID-19 in children The following information has been developed based on emerging information and evidence around the clinical presentation and management of children with COVID-19. This information and advice will evolve rapidly. Nebulisers and high-flow use during COVID-19 pandemic Concerns around aerosolisation of respiratory viruses need to be considered when delivering respiratory support to paediatric patients. The has
processes in England, Wales and Northern Ireland Preparations Throughout these exceptional times, all professionals who look after children and young people, must continue to base their judgments on the best interests of the child or children that they are caring for. This fundamental of good paediatric practice is the constant that must not alter however much the circumstances change around us. Paediatricians and other colleagues involved in safeguarding children, looked after children (LAC), adoption (...) their judgements on the best interests of the child or children that they are caring for. This fundamental of good paediatric practice is the constant that must not alter, however much the circumstances change around us. Paediatricchild protection services should be seen as a critical service, that is adequately staffed and rotas maintained. This may mean that fewer child protection doctors cover the rotas in order to allow paediatricians with a range of skills to be deployed to other areas. Robust rotas
unilateral pneumonia and 30 myocardial damage. Of the four case reports, two describe infants, (1, 4) one a seven year old child, (2) , while the age of the fourth child is unclear. (3) The children’s presenting symptoms were largely consistent with the case series reported above. Of note is a ‘critically ill’ Evidence summary for natural history of COVID-19 in children Health Information and Quality Authority Page 3 of 13 child who rapidly progressed to acute respiratory distress syndrome, sepsis (...) that while a recovering infant’s pharyngeal swabs tested negative 10 days after admission, anal swabs were still positive, but were found to be negative when tested on day 26. (1) Xing et al. (6) found that clearance of viral RNA in respiratory tract occurred within two weeks after abatement of fever; however, it remained positive in stools of paediatric patients for longer than four weeks. In two children faecal swabs turned negative 20 days after throat swabs had tested negative, while that of another
contact transmission, one was a case series of patients admitted to a children’s hospital in China (n=10), (1) and one was an analysis of Local Heath Commissions' public disclosures in China (n=419 index patients, n=595 household secondary infections). (2) The case series confirmed transmission of COVID-19 from one child to family members. (1) This transmission was from an infant to both parents, who developed symptomatic COVID-19 seven days after looking after the infant. (1) The analysis of public (...) and that interviewees could not recall episodes of transmission from a child to an adult. (5) The emerging evidence in the included studies has highlighted child to adult and or family member transmission has the potential to occur, although at extremely low rates. The mathematical modelling study also concluded that COVID-19 has low transmissibility among children or people younger than 14 years. Some studies of familial transmission which describe presumed contact and transmission have not been included here
admission to hospital or HDU/ICU to maximise available resources Page 3 of 16 Paediatric Tracheostomy and Tracheostomy Long-Term Ventilated Care during the COVID Pandemic 07/04/2020 C. Doherty, R.Neal, S.Wilkinson, N.Bateman, I,Bruce, J.Russell, B.A.McGrath on behalf of the Paediatric working party NTSP www.tracheostomy.org.uk 2. Delivery of Established Care It is proposed that, for children who require Tracheostomy or Tracheostomy Long-Term Ventilation (Tracheostomy-LTV) care, the best approach (...) cleaning/changing of outer gloves/gown or apron between patients). High Risk Areas include: • Areas where COVID positive patients are managed • Areas where patients with an unknown but suspected COVID status are managed • Areas where Aerosol Generating Procedures occur frequently (ventilated children, including children with tracheostomies and tracheostomy-LTV) Page 5 of 16 Paediatric Tracheostomy and Tracheostomy Long-Term Ventilated Care during the COVID Pandemic 07/04/2020 C. Doherty, R.Neal
Nutritional evaluation of the neurologically impaired child Nutrition is of key importance in optimizing function and health in children with neurological impairment (NI). Challenges in quantifying individual needs and assessing nutritional status are barriers to determining the nutritional prescription. This practice point addresses common questions faced by clinicians caring for this population and uses available evidence to provide strategies to address these challenges. Keywords
in infants, children and adolescents. • Safe and effective pharmacological management of acute and procedural pain in children. • Safe and effective prescription of pharamacotherapy for complex pain conditions in childhood. GUIDANCE ON COMPETENCIES FOR PAEDIATRIC PAIN MEDICINE 5APPENDIX A: CURRICULUM 1. Basic sciences a. Development of nociception b. Mechanisms of hyperalgesia during development c. Age related changes in body composition, pharmacokinetics and pharmacodynamics 2. Pain assessment a. Acute (...) in children’s pain b. Level 2 training in safeguarding/child protection c. Transition of young people from paediatric to adult services GUIDANCE ON COMPETENCIES FOR PAEDIATRIC PAIN MEDICINE 6GUIDELINES B: COMPETENCIES FOR PRACTITIONERS IN PAIN MEDICINE WHO ARE INVOLVED IN A PAEDIATRIC PAIN SERVICE OR ARE THE LEAD FOR TRANSITION OF ADOLESCENTS TO ADULT SERVICES More detailed knowledge, particularly concerning neonates and premature infants, is required for practitioners specialising in paediatric pain
Renamed 2015 References 1. Murphy BP, Inder TE, Rooks V, et al. Posthaemorrhagic ventricu- lar dilatation in the premature infant: natural history and predictors of outcome. Arch Dis Child Fetal Neonatal Ed 2002; 87:F37–F41. 2. Rosenberg HK, Viswanathan V, Amodio J. Pediatric brain. In: McGahan JP, Goldberg BB (eds). Diagnostic Ultrasound. Vol 1. 2nd ed. New York, NY: Informa Healthcare; 2008:563–612. 3. Rumack CM, Levine D. Neonatal and infant brain imaging. In: Diagnostic Ultrasound. Vol 2. 5th ed (...) , Sanchez-Zaplana H, Ruiz JC, Jimenez-Cobo B. Rupture of intracranial arterial aneurysms in neonates: case report and review of the literature. J Child Neurol 2009; 24:208–214. 10. Wang HS, Kuo MF, Chang TC. Sonographic lenticulostriate vasculopathy in infants: some associations and a hypothesis. AJNR Am J Neuroradiol 1995; 16:97–102. 11. de Vries LS, Cowan FM. Evolving understanding of hypoxic- ischemic encephalopathy in the term infant. Semin Pediatr Neurol 2009; 16:216–225. 12. Govaert P. Prenatal
increased risk compared to middle aged 495 adults. 83 For a single CT examination of 200 mA, lifetime attributable cancer mortality risk is 1 in 496 1000-2500 for a 2.5-year-old child. 83 Thus, while chest CTs and to a much lesser extent sinus CTs 497 have a definite role in the evaluation of a child with cough, these should rarely be performed 498 unless other symptoms are present and ideally with prior consultation with a pediatric respiratory 499 specialist. 500 8. For children aged =14-years (...) . Published by Elsevier Inc. All rights reserved.Managing Chronic Cough as a Symptom in Children and Management 1 Algorithms: CHEST Guideline and Expert Panel Report 2 3 Anne B Chang, PhD; John J Oppenheimer, MD; FCCP; Richard S Irwin, MD, Master FCCP; on 4 behalf of the CHEST Expert Cough Panel* 5 6 Affiliations: Division of Child Health, Menzies School of Health Research (Dr Chang); Dept of 7 Respiratory and Sleep Medicine, Queensland Children’s Hospital, Qld Uni of Technology 8 Queensland, Australia
sequencing for infants in intensive care units: ascertainment of severe single-gene disorders and effect on medical management. JAMA Pediatr. 2017;171: e173438. 9. Clark MM, Stark Z, Farnaes L, et al. Meta-analysis of the diagnostic and clinical utility of genome and exome sequencing and chromosomal microarray in children with suspected genetic diseases. NPJ Genom Med. 2018;3:16. 10. Nambot S, Thevenon J, Kuentz P, et al. Clinical whole-exome sequencing for the diagnosis of rare disorders with congenital (...) . 2017;19:1055–1063. 19. Nair P, Sabbagh S, Mansour H, et al. Contribution of next generation sequencing in pediatric practice in Lebanon. A study on 213 cases. Mol Genet Genomic Med. 2018;6:1041–1052. 20. Farnaes L, Hildreth A, Sweeney NM, et al. Rapid whole-genome sequencing decreases infant morbidity and cost of hospitalization. NPJ Genom Med. 2018;3:10. 21. Kaye AJ, Rand EB, Munoz PS, Spinner NB, Flake AW, Kamath BM. Effect of Kasai procedure on hepatic outcome in Alagille syndrome. J Pediatr
Randomised Trial , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Department of General Paediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands. 2 Department of Paediatrics, HAGA-Juliana Children's Hospital, Den Haag, The Netherlands. 3 Department of Public Health, Erasmus MC, Rotterdam, The Netherlands. 4 Department of Paediatrics, Flevoziekenhuis, Almere, The Netherlands. 5 Department of Paediatrics, Maasstad Ziekenhuis, Rotterdam, The Netherlands. 6 Department (...) Prescription in Children With Suspected Lower Respiratory Tract Infection in The Netherlands: A Stepped-Wedge Cluster Randomised Trial Josephine S van de Maat et al. PLoS Med . 2020 . Show details PLoS Med Actions . 2020 Jan 31;17(1):e1003034. doi: 10.1371/journal.pmed.1003034. eCollection 2020 Jan. Authors , , , , , , , , , , , , , Affiliations 1 Department of General Paediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands. 2 Department of Paediatrics, HAGA-Juliana Children's
International Collaborative, Melbourne, Victoria, Australia. 3 Division of Paediatrics and Emergency Medicine, School of Medicine, University of Western Australia, Perth, WA, Australia. 4 Emergency Department, Perth Children's Hospital, Perth, Western Australia, Australia. 5 Emergency Department, Queensland Children's Hospital, South Brisbane, Queensland, Australia. 6 Child Health Research Centre, Faculty of Medicine, University of Queensland, South Brisbane, Queensland, Australia. 7 Department of Emergency (...) Emergency Research, Murdoch Childrens Research Institute, Parkville, Victoria, Australia. 14 Children's Emergency Department, Starship Children's Hospital, Auckland, New Zealand. 15 Departments of Surgery and Paediatrics;Child and Youth Health, University of Auckland, Auckland, New Zealand. 16 Department of Women's and Child's Health, University of Padova, Padova, Italy. PMID: 32051126 DOI: Item in Clipboard Association of Clinically Important Traumatic Brain Injury and Glasgow Coma Scale Scores