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Latest & greatest articles for children
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on children or other clinical topics then use Trip today.
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in preschoolchildren and their families in Xi'an, China . PLoS ONE . 2013 ; 8 ( 10 ):e77273. 11 Tabbers MM , Dilorenzo C , Berger MY , et al. Evaluation and treatment of functional constipation in infants and children: evidence‐based recommendations from ESPGHAN and NASPGHAN . J Pediatr Gastroenterol Nutr . 2014 ; 58 ( 2 ): 265 – 281 . 12 Health NCC for W and C . Constipation in children and young people : Constipation Child young people diagnosis Manag idiopathic Child constipation Prim Second care (...) )—Motility Working Group (MWG) therefore has taken the opportunity to provide guidance on the use of ARM/HRAM in children with CC and/or FI. 2 METHODS The authors conducted structured literature search using PubMed between 2004 and 2018 for literature published in English using all possible combinations of the following keywords: (a) “anorectal,” “rectoanal,” “malformat*,” “Hirschsprung*,” “dyssynerg*,” “constipat*”; (b) “manometr*,” “physiolog*”; and (c) “paediatric*,” “pediatric*,” “child*,” “neonat
and biological products in pediatric patients–FDA. Final rule. Fed Regist. 1998;63(231):66631–66672. - American Academy of Pediatrics, American Pain Society. The assessment and management of acute pain in infants, children, and adolescents. Pediatrics. 2001;108(3):793–797. doi:10.1542/peds.108.3.793 - - Association of Paediatric Anaesthetists of Great Britain and Ireland. Good practice in postoperative and procedural pain management, 2nd edition. Paediatr Anaesth. 2012;22(suppl1):1–79. doi:10.1111/j.1460 (...) Grünenthal GmbH, Aachen, Germany. 2 Division of Paediatric Pharmacology and Pharmacometrics, University of Basel Children's Hospital, Basel, Switzerland. 3 Division of Clinical Pharmacology, Children's National Medical Center, Washington, DC, USA. PMID: 32009813 PMCID: DOI: Item in Clipboard Full-text links Cite Abstract Background: Well-controlled trials of analgesics in the pediatric population are scarce. Tapentadol is a strong centrally acting analgesic which has undergone a pediatric development
in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Int J Nurs Stud Actions . 2020 Apr;104:103532. doi: 10.1016/j.ijnurstu.2020.103532. Epub 2020 Jan 24. The Effect of Expressed Breast Milk, Swaddling and Facilitated Tucking Methods in Reducing the Pain Caused by Orogastric Tube Insertion in Preterm Infants: A Randomized Controlled Trial , Affiliations Expand Affiliations 1 Child Health Nursing Department (...) , Faculty of Health Sciences, Gumuşhane University, Gümüşhane 29000, Turkey. 2 Child Health Nursing Department, Nursing Faculty, Akdeniz University, Antalya 07058, Turkey. Electronic address: email@example.com. PMID: 32062050 DOI: Item in Clipboard The Effect of Expressed Breast Milk, Swaddling and Facilitated Tucking Methods in Reducing the Pain Caused by Orogastric Tube Insertion in Preterm Infants: A Randomized Controlled Trial Vildan Apaydin Cirik et al. Int J Nurs Stud . 2020 Apr . Show details
Med Actions . 2020 Feb 19;S0735-6757(20)30109-1. doi: 10.1016/j.ajem.2020.02.036. Online ahead of print. Emergency Physician Performed Ultrasound-Assisted Lumbar Puncture in Children: A Randomized Controlled Trial , , , , Affiliations Expand Affiliations 1 Department of Pediatric Emergency Medicine, CHU Sainte-Justine, Montreal, QC, Canada. Electronic address: firstname.lastname@example.org. 2 Department of Pediatric Emergency Medicine, CHU Sainte-Justine, Montreal, QC, Canada. 3 Department of Pediatric (...) Emergency Medicine, Montreal Children's Hospital, Montreal, QC, Canada. PMID: 32204980 DOI: Item in Clipboard Emergency Physician Performed Ultrasound-Assisted Lumbar Puncture in Children: A Randomized Controlled Trial Jaryd Zummer et al. Am J Emerg Med . 2020 . Show details Am J Emerg Med Actions . 2020 Feb 19;S0735-6757(20)30109-1. doi: 10.1016/j.ajem.2020.02.036. Online ahead of print. Authors , , , , Affiliations 1 Department of Pediatric Emergency Medicine, CHU Sainte-Justine, Montreal, QC, Canada
with patients and minimising Communicating with patients and minimising risk risk 1.1 Communicate with patients and their parents or carers, and support their mental wellbeing to help alleviate any anxiety and fear they may have about COVID-19. Signpost to charities, support groups (including NHS Volunteer Responders), UK government guidance on supporting children and young people's mental health and wellbeing and Royal College of Paediatrics and Child Health resources for parents and carers. 1.2 Reassure (...) College of Paediatrics and Child Health shielding guidance for children and young people • UK government advice on shielding and protecting people defined on medical grounds as extremely vulnerable from COVID-19 • UK government guidance on social distancing for everyone in the UK. 1.8 Be aware that babies and children cannot always be shielded in the same way as adults. Discuss this with patients (if appropriate), their parents or carers and specialist teams. Safeguarding Safeguarding 1.9 Be aware
Primary Care Interventions for Prevention and Cessation of Tobacco Use in Children and Adolescents: US Preventive Services Task Force Recommendation Statement. Tobacco use is the leading cause of preventable death in the US. An estimated annual 480 000 deaths are attributable to tobacco use in adults, including from secondhand smoke. It is estimated that every day about 1600 youth aged 12 to 17 years smoke their first cigarette and that about 5.6 million adolescents alive today will die (...) prematurely from a smoking-related illness. Although conventional cigarette use has gradually declined among children in the US since the late 1990s, tobacco use via electronic cigarettes (e-cigarettes) is quickly rising and is now more common among youth than cigarette smoking. e-Cigarette products usually contain nicotine, which is addictive, raising concerns about e-cigarette use and nicotine addiction in children. Exposure to nicotine during adolescence can harm the developing brain, which may affect
Prevalence of Continuous Pulse Oximetry Monitoring in Hospitalized Children With Bronchiolitis Not Requiring Supplemental Oxygen. US national guidelines discourage the use of continuous pulse oximetry monitoring in hospitalized children with bronchiolitis who do not require supplemental oxygen.Measure continuous pulse oximetry use in children with bronchiolitis.A multicenter cross-sectional study was performed in pediatric wards in 56 US and Canadian hospitals in the Pediatric Research (...) administration.The primary outcome, receipt of continuous pulse oximetry, was measured using direct observation. Continuous pulse oximetry use percentages were risk standardized using the following variables: nighttime (11 pm to 7 am), age combined with preterm birth, time after weaning from supplemental oxygen or flow, apnea or cyanosis during the present illness, neurologic impairment, and presence of an enteral feeding tube.The sample included 3612 patient observations in 33 freestanding children's hospitals
Selumetinib in Children with Inoperable Plexiform Neurofibromas. No approved therapies exist for inoperable plexiform neurofibromas in patients with neurofibromatosis type 1.We conducted an open-label, phase 2 trial of selumetinib to determine the objective response rate among patients with plexiform neurofibromas and to assess clinical benefit. Children with neurofibromatosis type 1 and symptomatic inoperable plexiform neurofibromas received oral selumetinib twice daily at a dose of 25 mg per (...) square meter of body-surface area on a continuous dosing schedule (28-day cycles). Volumetric magnetic resonance imaging and clinical outcome assessments (pain, quality of life, disfigurement, and function) were performed at least every four cycles. Children rated tumor pain intensity on a scale from 0 (no pain) to 10 (worst pain imaginable).A total of 50 children (median age, 10.2 years; range, 3.5 to 17.4) were enrolled from August 2015 through August 2016. The most frequent neurofibroma-related
Association between maternal and paternal mental illness and risk of injuries in children and adolescents: nationwide register based cohort study in Sweden. To determine the association between parental mental illness and the risk of injuries among offspring.Retrospective cohort study.Swedish population based registers.1 542 000 children born in 1996-2011 linked to 893 334 mothers and 873 935 fathers.Maternal or paternal mental illness (non-affective psychosis, affective psychosis, alcohol (...) or drug misuse, mood disorders, anxiety and stress related disorders, eating disorders, personality disorders) identified through linkage to inpatient or outpatient healthcare registers.Risk of injuries (transport injury, fall, burn, drowning and suffocation, poisoning, violence) at ages 0-1, 2-5, 6-9, 10-12, and 13-17 years, comparing children of parents with mental illness and children of parents without mental illness, calculated as the rate difference and rate ratio adjusted
Infectious diseases in children and adolescents in China: analysis of national surveillance data from 2008 to 2017. To outline which infectious diseases in the pre-covid-19 era persist in children and adolescents in China and to describe recent trends and variations by age, sex, season, and province.National surveillance studies, 2008-17.31 provinces in mainland China.4 959 790 Chinese students aged 6 to 22 years with a diagnosis of any of 44 notifiable infectious diseases. The diseases were (...) and tuberculosis to HIV/AIDS, particularly in males. Mortality from infectious diseases decreased steadily from 0.21 per 100 000 population in 2008 to 0.07 per 100 000 in 2017. Quarantinable conditions with high mortality have effectively disappeared. The incidence of notifiable infectious diseases in children and adolescents decreased from 280 per 100 000 in 2008 to 162 per 100 000 in 2015, but rose again to 242 per 100 000 in 2017, largely related to mumps and seasonal influenza. Excluding mumps
in sequencing technology, upper gastrointestinal series with small bowel follow-through study are being used less frequently in pediatric IBD. Ultrasound, MRE, and CT are now part of the management at most centers. In the young child, however, MRE can be difficult, therefore, ultrasound of the small bowel by an experienced radiologist can be used to delineate the extent of disease. THERAPEUTIC STRATEGIES FOR CHILDREN WITH VERY EARLY-ONSET INFLAMMATORY BOWEL DISEASE VEO-IBD has become a model for the change (...) of Immunology and Allergy, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA ‡ Division of Gastroenterology, Hepatology, and Nutrition, Cedar-Sinai Medical Center, Los Angeles, CA § Division of Gastroenterology, Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA || Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School
nebulisers note that salbutamol can only be bought in small quantities in pharmacies keep themselves informed as the situation changes. Key points The was updated in 2019 with specific guidelines for children aged 1–5 years and 6–11 years old. An asthma diagnosis should always be supported with spirometry, or a treatment trial for children unable to undergo spirometry. Asthma should not be diagnosed in infants aged less than 12 months old. Review short-acting beta 2 agonist (SABA) use regularly to avoid (...) and followed by parents and carers. Practice Review – Paediatric asthma: diagnosis and treatment Australian GPs recently received a Practice Review designed to help them reflect on reflect on spirometry referrals and their prescribing of asthma medicines for children with asthma. It was developed in collaboration with GPs and has been sent to approximately 30,000 prescribers nationally, including all GPs. Find COVID-19 updates for asthma Access a sample report Read FAQs about the PBS and MBS Practice
paediatrics Plos One Paediatric journals ADC JAMA Pediatrics Lancet Child and Adolescent medicine BMC Pediatrics Respiratory journals Lancet Res Med Thorax Chest BMC respiratory medicine https://ourworldindata.org/coronavirus https://www.arcgis.com/apps/opsdashboard/index.html - /bda7594740fd40299423467b48e9ecf6 Table 1: epidemiological, demographic, and clinical characterisation observational studies relevant to COVID-19 in children (and selected adult studies – the adult studies will not be routinely (...) paediatricians. Separate guidance has been produced by the Paediatric Intensive Care Society on Covid-19 infection relevant to the paediatric critical care community: https://picsociety.uk/covid19/ 1 Summary of the guidance: Reassure parents and involve them in caring for their child, keep up-to-date using the evidence in Appendix 1 of this guidance, and communicate well with colleagues Be extra-vigilant in children with pre-existing conditions but reassure parents that the risks of comorbidities is much
Pulmonary surfactant for respiratory distress syndrome in premature infants 1 Driving better decision-making in healthcare Pulmonary surfactant for treating respiratory distress syndrome in premature infants Technology Guidance from the MOH Drug Advisory Committee Published on 1 April 2020 Guidance recommendations The Ministry of Health’s Drug Advisory Committee has recommended: ? Calfactant 105 mg/3 ml and 210 mg/6 ml intratracheal suspension vials for treating respiratory distress syndrome (...) in premature infants. Subsidy status Calfactant 105 mg/3 ml and 210 mg/6 ml intratracheal suspension vials are recommended for inclusion on the MOH Standard Drug List (SDL) for the abovementioned indication. SDL does not apply to beractant 200 mg/8 ml vial and poractant alfa 120 mg/1.5 ml vial. 2 Driving better decision-making in healthcare Factors considered to inform the recommendations for subsidy Technology evaluation 1.1 1.2 1.3 The MOH Drug Advisory Committee (“the Committee”) considered the evidence
in children. Weiss SL, Peters MJ, Alhazzani W, et al. Intensive Care Med. 2020 Feb;46(Suppl 1):10-67. doi: 10.1007/s00134-019-05878-6. How to manage a paediatric cardiac arrest in suspected/confirmed cases • Do not use the hospital cardiac arrest team • Devise a modified protocol beforehand with identified members of senior paediatric team and ensure all are mask fit tested and able to don and doff PPE • If the child is intubated and ventilated – try not to disconnect from the ventilator when doing CPR (...) PICS Guidance on management of critically ill children with Covid-19 infection Sinha/Ramnarayan/Fraser v4.0 14.03.20 PAEDIATRIC CRITICAL CARE COVID-19 GUIDANCE Key points • Coronavirus (COVID-19) is an air-borne disease, characterized by its ability to spread rapidly among healthcare staff who are not properly protected. It can be difficult to rapidly diagnose and has a high case-fatality rate in adults but generally appears to be a mild illness in children. • The key considerations for all
for childhood depression, clinicians contend with sparse evidence and are concerned about harms associated with treatment. Methods. We conducted a systematic review to evaluate the efficacy, comparative effectiveness, and moderators of benefits and harms of available nonpharmacological and pharmacological treatments for children and adolescents with a confirmed diagnosis of a depressive disorder (DD)—major depressive disorder (MDD), persistent depressive disorder (previously termed dysthymia) or DD (...) to harm for interventions for childhood depression 137 Table 68. Evidence map for interventions for childhood depression Error! Bookmark not defined. Figures Figure A. Analytic framework for depression in children and adolescents ES-3 Figure B. Article flow diagram ES-6 Figure 1. Analytic framework for depression in children and adolescents 6 Figure 2. Article flow diagram 15 Appendixes Appendix A. Search Strategy Appendix B. Inclusion/Exclusion Criteria Appendix C. Excluded Studies Appendix D. Study
Committee, Canadian Paediatric Society, Public Health Agency of Canada References Le Saux N; Canadian PaediatricPaediatric Society, Infectious Diseases and Immunization Committee. Current epidemiology and guidance for COVOD-19 caused by SARS-CoV-2 virus in children: March 2020: https://www.cps.ca/en/documents/position/current-epidemiology-and-guidance-for-covid-19-march-2020 Xia W, Shao J, Guo Y, Peng X, Li Z, Hu D. Clinical and CT features in pediatric patients with COVID-19 infection: Different (...) Can NSAIDs be used in children when COVID-19 is suspected? Can NSAIDs be used in children when COVID-19 is suspected?Can NSAIDs be used in children when COVID-19 is suspected? | Canadian Paediatric Society A home for paediatricians. A voice for children and youth. Current: Can NSAIDs be used in… Practice Point Can NSAIDs be used in children when COVID-19 is suspected? Posted: Mar 24 2020 The Canadian Paediatric Society gives permission to print single copies of this document from our website
Consensus guidelines for managing the airway in children with COVID-19 1 Consensus guidelines for managing the airway in children with COVID-19; Highlighting differences in practice from adult guidelines Guidelines from the Association of Anaesthetists, the Difficult Airway Society, the Intensive Care Society, the Faculty of Intensive Care Medicine and the Royal College of Anaesthetists, Paediatric Intensive Care Society, Association of Paediatric Anaesthetists T. M. Cook, 1 K. El-Boghdadly, 2 (...) Lothian, Edinburgh, UK 5 Consultant, Department of Anaesthesia, Royal National Throat Nose and Ear Hospital and University College London Hospitals NHS Foundation Trust, London, UK 6 Consultant, Department of Anaesthesia and Intensive Care Medicine, Warrington and Halton NHS Foundation Trust, Warrington, UK 7 Consultant, Paediatric Intensive Care, Bristol Royal Hospital for Children, UK 8 Children’s Acute Transport Service (CATS), Great Ormond Street Hospital, UK 9 Consultant, Paediatric Intensive