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The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on children or other clinical topics then use Trip today.
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childhood obesity in Asia: an overview of intervention programmes. Obes Rev. 2016;17:1103–15. 10.1111/obr.12435 - - Show all 36 references Publication types Randomized Controlled Trial Actions Research Support, Non-U.S. Gov't Actions MeSH terms Asian Continental Ancestry Group Actions Body Mass Index Actions Child Actions Child, Preschool Actions China Actions Cost-Benefit Analysis Actions Diet, Healthy Actions Exercise Actions Female Actions Health Promotion / methods * Actions Humans Actions Life (...) Technol Assess 21 (1), 1-180. Jan 2017. PMID 28059054. - Randomized Controlled Trial Families for Health was neither effective nor cost-effective for the management of obesity in children aged 6-11 years, in comparison with usual care. Further exploration … A Martin et al. Cochrane Database Syst Rev 3 (3), CD009728. 2018. PMID 29499084. - Review Despite the large number of childhood and adolescent obesity treatment trials, we were only able to partially assess the impact of obesity treatment
), NLR (negative LR = 0.1) and IMA/albumin ratio (negative LR = 0.1) can serve a … F Sarac et al. J PaediatrChild Health 55 (10), 1247-1250. Oct 2019. PMID 30723978. Our study shows that IMA, together with WBC and CRP, may be a biomarker capable of assisting the differential diagnosis of acute abdominal pain in children and distinguis … R Benabbas et al. Acad Emerg Med 24 (5), 523-551. May 2017. PMID 28214369. - Review Presence of AA is more likely in patients with undifferentiated abdominal pain (...) Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation World J Surg Actions 2019 Dec 9 [Online ahead of print] Is Ischemia-Modified Albumin a Reliable Marker in Accurate Diagnosis of Appendicitis in Children? , , , , , , , , Affiliations Expand Affiliations 1 Department of Pediatrics, Division of Pediatric Emergency Care, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey. 2 Department
Yield of a Public Health Screening of Children for Islet Autoantibodies in Bavaria, Germany. Public health screening for type 1 diabetes in its presymptomatic stages may reduce disease severity and burden on a population level.To determine the prevalence of presymptomatic type 1 diabetes in children participating in a public health screening program for islet autoantibodies and the risk for progression to clinical diabetes.Screening for islet autoantibodies was offered to children aged 1.75 (...) to 5.99 years in Bavaria, Germany, between 2015 and 2019 by primary care pediatricians during well-baby visits. Families of children with multiple islet autoantibodies (presymptomatic type 1 diabetes) were invited to participate in a program of diabetes education, metabolic staging, assessment of psychological stress associated with diagnosis, and prospective follow-up for progression to clinical diabetes until July 31, 2019.Measurement of islet autoantibodies.The primary outcome was presymptomatic
consistently high; data from the first 3 months of 2018 showed that 92.5% of children had completed the primary immunizations by their first birthday and 87.9% had received all three doses by 2 years. From September 2015 through August 2018, the incidence of meningococcal group B disease in England (average annual birth cohort, approximately 650,000 infants) was significantly lower in vaccine-eligible cohorts than the expected incidence (63 observed cases as compared with 253 expected cases; incidence rate (...) Vaccination of Infants with Meningococcal Group B Vaccine (4CMenB) in England. In September 2015, the United Kingdom introduced the multicomponent meningococcal group B vaccine (4CMenB, Bexsero) into its publicly funded national immunization program at a reduced two-dose priming schedule for infants, with a 12-month booster.Using data from enhanced national surveillance of invasive meningococcal disease in England, we evaluated the effect of vaccination on the incidence of meningococcal group B
A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants. High-dose erythropoietin has been shown to have a neuroprotective effect in preclinical models of neonatal brain injury, and phase 2 trials have suggested possible efficacy; however, the benefits and safety of this therapy in extremely preterm infants have not been established.In this multicenter, randomized, double-blind trial of high-dose erythropoietin, we assigned 941 infants who were born at 24 weeks 0 days to 27 (...) neurodevelopmental impairment at 22 to 26 months of postmenstrual age. Severe neurodevelopmental impairment was defined as severe cerebral palsy or a composite motor or composite cognitive score of less than 70 (which corresponds to 2 SD below the mean, with higher scores indicating better performance) on the Bayley Scales of Infant and Toddler Development, third edition.A total of 741 infants were included in the per-protocol efficacy analysis: 376 received erythropoietin and 365 received placebo
JAK Inhibitor Therapy in a Child with Inherited USP18 Deficiency. Deficiency of ubiquitin-specific peptidase 18 (USP18) is a severe type I interferonopathy. USP18 down-regulates type I interferon signaling by blocking the access of Janus-associated kinase 1 (JAK1) to the type I interferon receptor. The absence of USP18 results in unmitigated interferon-mediated inflammation and is lethal during the perinatal period. We describe a neonate who presented with hydrocephalus, necrotizing cellulitis
Major cardiac events for adult survivors of childhood cancer diagnosed between 1970 and 1999: report from the Childhood Cancer Survivor Study cohort. To investigate the impact of modifications to contemporary cancer protocols, which minimize exposures to cardiotoxic treatments and preserve long term health, on serious cardiac outcomes among adult survivors of childhood cancer.Retrospective cohort study.27 institutions participating in the Childhood Cancer Survivor Study.23 462 five year (...) associated with a reduced risk of coronary artery disease among adult survivors of childhood cancer. Additional follow-up is needed to investigate risk reductions for other cardiac outcomes.ClinicalTrials.gov NCT01120353.Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
Clinicians prescribe antibiotics for childhood respiratory tract infection based on assessment, rather than parental expectation. The studyCabral C, Horwood J, Symonds J, et al. Understanding the influence of parent-clinician communication on antibiotic prescribing for children with respiratory tract infections in primary care: a qualitative observational study using a conversation analysis approach. BMC Fam Pract 2019;20:102.This project was funded by the NIHR School for Primary Care Research
Infants born to hepatitis B-infected mothers: immunoglobulin policy Infants born to hepatitis B-infected mothers: immunoglobulin policy - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Infants born to hepatitis B-infected mothers: immunoglobulin policy Policy on the use (...) of passive immunisation with hepatitis B immunoglobulin (HBIG) for infants born to hepatitis B infected mothers. Published 12 August 2008 Last updated 17 January 2020 — From: Documents If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email . Please tell us what format you need. It will help us if you say what assistive technology you use. Details This document summarises the policy and evidence for passive immunisation
Dance Intervention for Mexican Family Caregivers of Children With Developmental Disability: A Pilot Study. Introduction: There are 7.1 million people living with a disability in Mexico. Of these individuals, 7% are children and adolescents with developmental disabilities. Mexican women caring for children with a developmental disability are at risk of psychological stress, which may be prevented with physical activity such as dance. Therefore, the purpose of this pilot study was to examine (...) (a) the feasibility of implementing the dance intervention, (b) the mothers' satisfaction with the intervention, and (c) the changes in stress level experienced by the mothers on completion of the intervention. Method: A one-group pretest-posttest design was used. The Salsa dance intervention was given in nine 60-minute sessions, twice a week in Veracruz, Mexico. The sample included 14 mothers of children with disabilities. The outcome, stress level, was measured with the validated Questionnaire of Perceived
Larotrectinib (Vitrakvi) - adult and pediatric patients with solid tumours Search Page - Drug and Health Product Register Language selection Search and menus Search Search website Search Topics menu You are here: Summary Basis of Decision - - Health Canada Expand all Summary Basis of Decision (SBD) for Contact: Summary Basis of Decision (SBD) documents provide information related to the original authorization of a product. The for is located below. Recent Activity for SBDs written for approved
and pregnancy: potential long-term effects in children FEATURED REVIEW Many women who could become pregnant are exposed to antiepileptic drugs. Yet most of the antiepileptic drugs taken by pregnant women expose the unborn child to the risk of malformations, fetotoxic effects and neonatal disorders. What are the long-term effects of the most widely used antieleptics on children exposed in utero, and how do they compare? Full review (8 pages) available for download by subscribers. Abstract What are the main (...) function, sometimes with maladaptive behaviour. The 2018 French study also showed a risk of learning disabilities in the 500 children exposed in utero to topiramate. With gabapentin, there are concerns over a potential risk of early mental, behavioural and developmental disorders. Data are available on too few pregnancies exposed to levetiracetam to determine its long-term consequences. In summary , as of mid-2019, no antiepileptic drugs are risk-free for the unborn child. Lamotrigine
as fear and mistrust of the health system. These individual and system-level factors result in delays in TB diagnoses, ongoing transmission, poorer outcomes, and lower treatment completion rates. Children are especially vulnerable, as they are more likely to develop disease once infected with TB bacteria and to experience life-threatening conditions such as TB meningitis. Paediatric health professionals can help to increase TB awareness and literacy, reduce stigma and discrimination, and ultimately (...) Tuberculosis among First Nations, Inuit and Métis children and youth in Canada: Beyond medical management First Nations, Inuit and Métis people in Canada continue to be disproportionately affected by tuberculosis (TB), a disparity rooted primarily in factors such as poverty, crowded and inadequate housing, food insecurity, and inequitable health care access. Historical TB control practices in Canada have contributed to stigma and discrimination toward those with the disease, as well
of Colorado, Aurora, CO; Section of Pediatric Emergency Medicine, Children's Hospital Colorado, Aurora, CO. Electronic address: Halden.email@example.com. 2 Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO. 3 Adult and Child Consortium for Health Outcomes Research and Delivery Science, University of Colorado, Aurora, CO. 4 Department of Pediatrics, University of Colorado, Aurora, CO; Section of Pediatric Emergency Medicine, Children's Hospital Colorado (...) , Aurora, CO; Center for Clinical Effectiveness, Children's Hospital Colorado, Aurora, CO. 5 Division of Critical Care, Department of Pediatrics, British Columbia Children's Hospital, Vancouver, British Columbia, Canada; Department of Pediatrics and Emergency Medicine, University of British Columbia, Vancouver, BC, Canada. 6 Research Informatics, Children's Hospital Colorado, Aurora, CO. 7 Department of Pediatrics, University of Colorado, Aurora, CO; Adult and Child Consortium for Health Outcomes
in visual attention/task switching. Nurse-visited children showed improved behavi … DL Olds et al. Pediatrics 120 (4), e832-45. Oct 2007. PMID 17908740. - Randomized Controlled Trial By child age 9, the program reduced women's rates of subsequent births, increased the intervals between the births of first and second children, increased the stability o … DL Olds et al. Pediatrics 114 (6), 1550-9. Dec 2004. PMID 15574614. - Clinical Trial This program of prenatal and infancy home-visiting by nurses (...) infants have a positive influence on cognitive and motor outcomes during infancy, with cognitive benefits persisting into presch … Show more similar articles Cited by 1 PubMed Central articles DL Olds et al. Pediatrics 144 (6). Dec 2019. PMID 31748253. Through child age 18, the program reduced public-benefit costs, an effect more pronounced for mothers with higher psychological resources and mediated by subsequent pregn … LinkOut - more resources Full Text Sources Full-text links [x] [x] Citation text
introduced new restrictions following continued reports of cardiac side effects (see later section). At the time, there were limited data to support paediatric use in the relief of the symptoms of nausea and vomiting, and studies were requested to provide further data to support efficacy. A multicentre, double-blind, randomised, placebo-controlled, parallel-group, prospective evaluated the safety and efficacy of domperidone in 292 children with acute gastroenteritis aged between 6 months and 12 years (...) , an estimated 5700–7500 children aged 0–11-years were prescribed domperidone in the UK in 2018 for any indication. Article citation: Drug Safety Update volume 13, issue 5: December 2019: 1. Leitz G, et al. Safety and efficacy of low-dose domperidone for treating nausea and vomiting due to acute gastroenteritis in children. J Pediatr Gastroenterol Nutr 2019; 69: 425–30. The information presented here is based in part on data from the Clinical Practice Research Datalink however, the interpretation
of Melbourne, Australia; Critical Sciences, Murdoch Children's Research Institute, Melbourne, Australia. Electronic address: firstname.lastname@example.org. 2 Department of Pediatrics, University of Alberta, Edmonton, Canada; Centre for the Studies of Asphyxia and Resuscitation, Royal Alexandra Hospital, Edmonton, Canada. Electronic address: email@example.com. 3 Newborn Services, The Royal Women's Hospital, Melbourne, Australia; Departments of Obstetrics and Gynecology, University of Melbourne (...) of Obstetrics and Gynecology, University of Melbourne, Australia; Critical Sciences, Murdoch Children's Research Institute, Melbourne, Australia. Electronic address: firstname.lastname@example.org. PMID: 31518615 DOI: Item in Clipboard A Randomized Trial of Oropharyngeal Airways to Assist Stabilization of Preterm Infants in the Delivery Room C Omar F Kamlin et al. Resuscitation . Nov 2019 Show details Resuscitation Actions , 144, 106-114 Authors , , , , , , , , Affiliations 1 Newborn Services, The Royal Women's
of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia. 3 Duke-NUS Medical School, Singapore, Singapore. 4 Paediatric Emergency Department, Imperial College Hospital NHS Healthcare Trust, London, UK. 5 Department of Emergency Medicine, KK Women's and Children's Hospital, Singapore, Singapore Chong.Shu-Ling@kkh.com.sg. PMID: 31653694 DOI: Item in Clipboard Analysis of Emergency Department Prediction Tools in Evaluating Febrile Young Infants at Risk for Serious Infections (...) your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Emerg Med J Actions , 36 (12), 729-735 Dec 2019 Analysis of Emergency Department Prediction Tools in Evaluating Febrile Young Infants at Risk for Serious Infections , , , , Affiliations Expand Affiliations 1 Department of Emergency Medicine, KK Women's and Children's Hospital, Singapore, Singapore. 2 Faculty
. In children with cerebral palsy, as many as 92% suffer from serious GI symptoms. Such conditions can lead to insufficient caloric intake, a broad spectrum of GI and nutritional complications and associated clinical conditions, including respiratory infections and chronic aspiration, as well as a significant impact on quality of life for the patient and carer . Oral feeding is preferred in children with NI. The duration of a trial of oral feeding though depends on the child’s age and severity (...) of malnutrition. This guide, produced by the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), provides recommendations and a systematic approach for the care of paediatric patients with NI and should be read in conjunction with the ESPGHAN Clinical Advice Guides on: Methods and Recommendations for Nutritional Management and Requirements for Children with Neurological Impairments Common Gastrointestinal Issues for Children with Neurological Impairments: Evaluation, Treatment