Latest & greatest articles for colorectal cancer

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Top results for colorectal cancer

1. Role of gastrointestinal endoscopy in the screening of digestive tract cancers in Europ

because of palliative treatment and new biological treatments for advanced disease. BetterunderstandingofthenaturalhistoryofGIcancershas shown that most of them are preceded by slowly progressing precancerous conditions or lesions, as well as by early invasive stages, therefore providing opportunities for effective inter- ventions. Beyond the classic adenoma–carcinoma sequence for colorectal carcinogenesis, similar pathways based on metaplasia–dysplasia–cancer progression have been shown for upper GI (...) leadtounderuseorpoorresourcingofhealthfacilities involved inprovidingscreeningservices, with consequent failuretofully realizethe potential benefits to patients. Methods In 2017, the European Society of Gastrointestinal Endoscopy (ESGE) Governing Board established a task force (Public Affairs Working Group led by A.S.) to produce a Position Statement concerning the value of endoscopy for screening purposes in GI cancers. The most prevalent digestive cancers (esophageal squamous cellcarcinoma,esophagealadenocarcinoma,gastric carcinoma

2020 European Society of Gastrointestinal Endoscopy

2. Incidence of Incisional Hernia Repair After Laparoscopic Compared to Open Resection of Colonic Cancer: A Nationwide Analysis of 17,717 Patients (Abstract)

comprised of patients undergoing resection for colonic cancer between January 2007 and March 2016 according to the Danish Colorectal Cancer Group database. Patients who subsequently underwent IHR were identified in the Danish Ventral Hernia Database, from which information about the priority of the hernia repair and the size of the fascial defect was retrieved.The study included 17,717 patients, of whom 482 (2.7%) underwent subsequent IHR during a median follow-up of 4.7 (interquartile range 2.8-6.9 (...) Incidence of Incisional Hernia Repair After Laparoscopic Compared to Open Resection of Colonic Cancer: A Nationwide Analysis of 17,717 Patients It remains unknown whether laparoscopic compared to open surgery translates into fewer incisional hernia repairs (IHR). The objectives of the current study were to compare the long-term incidence of IHR and the size of repaired hernias between patients subjected to laparoscopic or open resection of colonic cancer.This was a nationwide cohort study

2020 EvidenceUpdates

3. Avapritinib (Ayvakit) - adults with unresectable or metastatic gastrointestinal stromal tumor (GIST)

Avapritinib (Ayvakit) - adults with unresectable or metastatic gastrointestinal stromal tumor (GIST) Drug Approval Package: AYVAKIT AYVAKIT " /> U.S. Department of Health and Human Services Search FDA Submit search Drug Approval Package: AYVAKIT Company: Blueprint Medicines Corporation Application Number: 212608 Approval Date: 01/09/2020 trong> Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. FDA Approval Letter and Labeling (PDF

2020 FDA - Drug Approval Package

4. Colorectal cancer

with early rectal cancer 23 Preoperative treatment for people with rectal cancer 24 Surgery for people with rectal cancer 26 Surgical technique for people with rectal cancer 27 People with locally advanced or recurrent rectal cancer 28 Surgical volumes for rectal cancer operations 29 Preoperative treatment for people with colon cancer 30 Duration of adjuvant chemotherapy for people with colorectal cancer 30 Colonic stents in acute large bowel obstruction 32 Molecular biomarkers to guide systemic anti (...) , and pT4 and/or pN2), performance status, any comorbidities, age and personal preferences. T o find out why the committee made the recommendation on duration of adjuvant chemotherapy for people with colorectal cancer and how it might affect practice, see rationale and impact. Colonic stents in acute large bowel obstruction Colonic stents in acute large bowel obstruction 1.3.15 Consider stenting for people presenting with acute left-sided large bowel obstruction who are to be treated with palliative

2020 National Institute for Health and Clinical Excellence - Clinical Guidelines

5. Dataset for histopathological reporting of gastrointestinal stromal tumours

infiltrates are prognostic factors in localized gastrointestinal stromal tumors. Cancer Res 2013;73:3499–3510. 29. Brierley J, Gospodarowicz MK, Wittekind C. TNM classification of malignant tumours (8th edition). Oxford, UK: Wiley-Blackwell, 2017. CEff 090120 16 V3 Final Appendix A SNOMED coding Topography Tumour site SNOMED 2/3 code SNOMED CT terminology SNOMED CT code Oesophagus T-62000/T-56000 Entire oesophagus (body structure) 181245004 Stomach T-63000/T-57000 Entire stomach (body structure) 181246003 (...) allows formulation of a definitive management plan but also is used to: • provide accurate and complete data for cancer registration • provide feedback to other clinical specialties, including surgery, radiology and oncology • allow for high-quality clinical audit and research. GISTs are now considered the most common connective tissue tumour of the gastrointestinal (GI) tract. They have been the subject of great interest over the past decade as a much deeper understanding of the underlying molecular

2020 British Society of Gastroenterology

6. Cancer Screening: Interventions Engaging Community Health Workers – Colorectal Cancer

or cancer* or neoplasm* or tumo?r* or carcinoma* or adenocarcinoma*) and (breast or cervical or cervix or colon or colorectal or crc)).ti,ab. 4. 2 or 3 5. 1 and 4 6. colonography, computed tomographic/ or colonoscopy/ or endoscopy, gastrointestinal/ or sigmoidoscopy/ or ((occult blood.ti,ab. or occult blood/) and (feces/ or (faeces or fecal or faecal or colorectal).ti,ab.)) or (enema/ and barium sulfate/) 7. mammography/ or mammogra*.ti,ab. 8. (colonography or colonoscop* or fobt or sigmoidoscop*).ti,ab (...) or screening or "early detection of cancer").mp. 2. ((neoplasm* or ductal breast carcinoma* or "hereditary breast and ovarian cancer syndrome") and (diagnosis or prevention)).mp. [mp=title, abstract, heading word, table of contents, key concepts, original title, tests & measures] 3. ((adenoma* or neoplasia or cancer* or neoplasm* or tumo?r* or carcinoma* or adenocarcinoma*) and (breast or cervical or cervix or colon or colorectal or crc)).mp. 4. 2 or 3 5. 1 and 4 6. ((colonography or colonoscopy

2020 Community Preventive Services Task Force

7. Advanced imaging for detection and differentiation of colorectal neoplasia: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

; 51Introduction Colonoscopy is the key examination technique in colorectal cancer (CRC) screening programs for detection and treatment of early precursor lesions and timely diagnosis of colorectal cancer [1,2]. The quality of colonoscopy, which depends on both bowel preparation and examination technique, is the main determining factor that drives the protective effect of this invasive examination in decreasing the societal disease burden [3–5]. Over the last 15 years, several new techniques to improve polyp (...) in the surveillance of SPS patients. However, its routine use must bebalanced against practical considerations. Bisschops Raf et al. Advanced imaging for detection and differentiation of colorectal neoplasia: ESGE Guideline – Update 2019 … Endoscopy 2019; 51Detection and differentiation ofcolorectal neoplasia in inflammatory bowel disease (IBD) Patients with long-standing or extensive ulcerative colitis (UC) or Crohn’s disease are at an increased risk of developing CRC compared to the average risk population

2020 European Society of Gastrointestinal Endoscopy

8. British Society of Gastroenterology/Association of Coloproctology of Great Britain and Ireland/Public Health England post-polypectomy and post-colorectal cancer resection surveillance guidelines Full Text available with Trip Pro

Sussex Hospitals NHS Foundation Trust, Chichester, UK. 6 Colorectal surgery, Raigmore Hospital, Inverness, UK. 7 Gastroenterology, Cardiff and Vale NHS Trust, Cardiff, UK. 8 Histopathology, Nottingham University Hospitals, Nottingham, UK. 9 Family History of Bowel Cancer Clinic, West Middlesex University Hospital, London, UK. 10 Imperial College, London, UK. 11 Histopathology, University College London, London, UK. 12 Centre for Medical Imaging, UCL, London, UK. 13 Endoscopy, St Marks Hospital (...) Abstract These consensus guidelines were jointly commissioned by the British Society of Gastroenterology (BSG), the Association of Coloproctology of Great Britain and Ireland (ACPGBI) and Public Health England (PHE). They provide an evidence-based framework for the use of surveillance colonoscopy and non-colonoscopic colorectal imaging in people aged 18 years and over. They are the first guidelines that take into account the introduction of national bowel cancer screening. For the first time, they also

2020 EvidenceUpdates

9. FOLFOXIRI Plus Panitumumab As First-Line Treatment of RAS Wild-Type Metastatic Colorectal Cancer: The Randomized, Open-Label, Phase II VOLFI Study (AIO KRK0109)

FOLFOXIRI Plus Panitumumab As First-Line Treatment of RAS Wild-Type Metastatic Colorectal Cancer: The Randomized, Open-Label, Phase II VOLFI Study (AIO KRK0109) FOLFOXIRI Plus Panitumumab As First-Line Treatment of RAS Wild-Type Metastatic Colorectal Cancer: The Randomized, Open-Label, Phase II VOLFI Study (AIO KRK0109) - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go (...) your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation J Clin Oncol Actions , 37 (35), 3401-3411 2019 Dec 10 FOLFOXIRI Plus Panitumumab As First-Line Treatment of RAS Wild-Type Metastatic Colorectal Cancer: The Randomized, Open-Label, Phase II VOLFI Study (AIO KRK0109

2020 EvidenceUpdates

10. Endoscopic management of Lynch syndrome and of familial risk of colorectal cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

repair genes in hereditary nonpolyposis colorectal cancer patients with small bowel cancer: International Society for Gastrointestinal Hereditary Tumours Collaborative Study. Clinical Cancer Res 2006; 12: 3389–3393 [80] Rodriguez-Bigas MA, Vasen HF, Lynch HT et al. Characteristics of small bowel carcinoma in hereditary nonpolyposis colorectal carci- noma. International Collaborative Group on HNPCC. Cancer 1998; 83: 240–244 [81] SchulmannK,BraschFE,KunstmannEetal.HNPCC-associatedsmall bowel cancer (...) cancer mortality in first- degree relatives ofearly-onset colorectal cancer cases. Dis Colon Rectum 2002; 45: 681–686 [107] Kune GA, Kune S, Watson LF. The role of heredity in the etiologyof large bowel cancer: data from the Melbourne Colorectal Cancer Study. World J Surg 1989; 13: 124–129 ; discussion 9–31 [108] Samadder NJ, Smith KR, Hanson H et al. Increased riskofcolorectal canceramongfamilymembersofallages,regardlessofageofindex case at diagnosis. Clin Gastroenterol Hepatol 2015; 13: 2305–2311

2020 European Society of Gastrointestinal Endoscopy

11. Investigating the Effect of Self-Care Training on Life Expectancy and Quality of Life in Patients with Gastrointestinal Cancer under Radiotherapy. Full Text available with Trip Pro

Investigating the Effect of Self-Care Training on Life Expectancy and Quality of Life in Patients with Gastrointestinal Cancer under Radiotherapy. A huge amount of the efforts made by health teams is dedicated to caring for cancer patients. This study has aimed to investigate the effect of self-care training on life expectancy and quality of life (QOL) in patients with gastrointestinal cancer who were under radiotherapy.In this clinical trial, 50 patients were selected using the block (...) training improved the QOL and life expectancy of patients with gastrointestinal cancer who were under radiotherapy. Therefore, self-care training is recommended to improve the QOL and the life expectancy of cancer patients.

2019 Asia-Pacific journal of oncology nursing Controlled trial quality: uncertain

12. Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy Full Text available with Trip Pro

Have inflammatory bowel disease Have hereditary syndromes that increase the risk of colorectal cancer, such as Lynch syndrome and familial adenomatous polyposis. Several factors influence individuals’ decisions whether to be screened, even when they are presented with the same information: Variation in an individual’s values and preferences A close balance of benefits versus harms and burdens (for example, for a baseline risk of 3%, FIT every two years results in five fewer deaths from colorectal (...) recommendations: an international comparison of high income countries . NHS. Bowel scope screening. . Navarro M , Nicolas A , Ferrandez A , Lanas A . Colorectal cancer population screening programs worldwide in 2016: An update . Levin TR , Corley DA , Jensen CD , et al . Effects of organized colorectal cancer screening on cancer incidence and mortality in a large community-based population . Cancer Research UK. Bowel cancer incidence statistics. . Danckert B FJ, Engholm G, Hansen HL, et al. NORDCAN: Cancer

2019 BMJ Rapid Recommendations

13. Bevacizumab (Zirabev) - colorectal cancer, non-small cell lung cancer, peritoneal cancer, glioblastoma

Bevacizumab (Zirabev) - colorectal cancer, non-small cell lung cancer, peritoneal cancer, glioblastoma Search Page - Drug and Health Product Register Language selection Search and menus Search Search website Search Topics menu You are here: Summary Basis of Decision - - Health Canada Expand all Summary Basis of Decision (SBD) for Contact: Summary Basis of Decision (SBD) documents provide information related to the original authorization of a product. The for is located below. Recent Activity

2019 Health Canada - Drug and Health Product Register

14. Colorectal Cancer

of Colorectal Liver Metastases 111 7.4.3. Tumor Markers 113 7.4.4. Specific Diagnostics for Rectal Cancer 114 7.5. Surgical Therapy with Curative Intention 117 7.5.1. Intraoperative Staging 117 7.5.1.1. Intra-Operative Pathological Examination 117 7.5.2. Radical Surgical Therapy of Colon Cancer 118 7.5.2.1. Extent of Lymph Node Dissection: 118 7.5.2.2. Complete Mesocolic Excision (CME) 120 7.5.2.3. Local Ablative Therapies for Liver Metastases 121 7.5.2.3.1. Radio-Frequency Ablation (RFA) 121 7.5.2.3.2 (...) (Hereditary Non-Polyposis Colorectal Cancer) 135 7.7.8. Cancers in Familial Adenomatous Polyposis (FAP) 136 1.1 Editors © German Guideline Program in Oncology | Evidenced-based Guideline for Colorectal Cancer | Version 2.1 | Januar 2019 6 7.7.9. Cancers in Ulcerative Colitis 136 7.8. Postoperative Histopathological Examination 137 7.8.1. Cancer-Grading Based on MSI-H 137 7.8.2. Number of LN to be Removed 138 7.8.3. Relevance of Distance Between the Tumor Margin and Resection Area of the Mesocolon in Colon

2019 German Guideline Program in Oncology

15. Endoscopic surveillance after surgical or endoscopic resection for colorectal cancer

Endoscopic surveillance after surgical or endoscopic resection for colorectal cancer Endoscopic surveillance after surgical or endoscopic resection for colorectal cancer: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Digestive Oncology (ESDO) Guideline – European Society of Gastrointestinal Endoscopy (ESGE) +49-89-9077936-11 Menu DOI https://doi.org/10.1055/a-0831-2522 Endoscopy 2019; 51: 266–277 © Georg Thieme Verlag KG Stuttgart· New York Explore the ESGE (...) website Menu Contact us +49-89-9077936-0 Follow us © 2004 - 2019 European Society of Gastrointestinal Endoscopy (ESGE). All Rights Reserved. |

2019 European Society of Gastrointestinal Endoscopy

16. Endoscopic management of Lynch syndrome and of familial risk of colorectal cancer

Endoscopic management of Lynch syndrome and of familial risk of colorectal cancer Endoscopic management of Lynch syndrome and of familial risk of colorectal cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – European Society of Gastrointestinal Endoscopy (ESGE) +49-89-9077936-11 Menu DOI https://doi.org/10.1055/a-1016-4977 | Endoscopy 2019; 51:1082–1093 Published online: 9.10.2019 © Georg Thieme Verlag KG Stuttgart · New York Explore the ESGE website Menu Contact us +49 (...) -89-9077936-0 Follow us © 2004 - 2019 European Society of Gastrointestinal Endoscopy (ESGE). All Rights Reserved. |

2019 European Society of Gastrointestinal Endoscopy

17. Advanced imaging for detection and differentiation of colorectal neoplasia

Advanced imaging for detection and differentiation of colorectal neoplasia Advanced imaging for detection and differentiation of colorectal neoplasia: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2019 – European Society of Gastrointestinal Endoscopy (ESGE) +49-89-9077936-11 Menu DOI https://doi.org/10.1055/a-1031-7657 | Endoscopy 2019; 51: 1155–1179 Published online: 11.11.2019 © Georg Thieme Verlag KG Stuttgart · New York Explore the ESGE website Menu Contact us +49 (...) -89-9077936-0 Follow us © 2004 - 2019 European Society of Gastrointestinal Endoscopy (ESGE). All Rights Reserved. |

2019 European Society of Gastrointestinal Endoscopy

18. Bowel cancer screening: imaging use

screening: imaging use Information about imaging practice standards for bowel cancer screening of individuals unsuitable for a colonoscopy. Published 1 November 2012 Last updated 14 October 2019 — From: Documents Ref: PHE publications gateway number: GW-810 HTML Details This publication explains the use of whole colon imaging as an alternative to a colonoscopy as part of the NHS Bowel Cancer Screening Programme ( 14 October 2019 Added new guidelines on CTC imaging in NHS bowel cancer screening. 1 (...) Bowel cancer screening: imaging use Bowel cancer screening: imaging use - GOV.UK GOV.UK uses cookies which are essential for the site to work. We also use non-essential cookies to help us improve government digital services. Any data collected is anonymised. By continuing to use this site, you agree to our use of cookies. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Register by 26 November to vote in the General Election on 12 December. Guidance Bowel cancer

2019 Public Health England

19. Colorectal cancer screening with faecal testing, sigmoidoscopy or colonoscopy: a systematic review and network meta-analysis Full Text available with Trip Pro

Colorectal cancer screening with faecal testing, sigmoidoscopy or colonoscopy: a systematic review and network meta-analysis Evaluate effectiveness, harms and burdens of faecal blood testing, sigmoidoscopy and colonoscopy screening for colorectal cancer over 15 years.We performed an update of a Cochrane systematic review, and performed network meta-analysis comparing randomised trials evaluating colorectal cancer screening with guaiac faecal occult blood test (gFOBT) (annual, biennial), faecal (...) immunochemical test (FIT) (annual, biennial), sigmoidoscopy (once-only) or colonoscopy (once-only) in a healthy population, aged 50-79 years. We conducted subgroup analysis on sex. Follow-up >5 years was required for analysis of colorectal cancer incidence and mortality.12 randomised trials proved eligible. Compared with no-screening, we found high certainty evidence for sigmoidoscopy screening slightly reducing colorectal cancer incidence (relative risk (RR) 0.76; 95% confidence interval (CI 0.70 to 0.83

2019 EvidenceUpdates

20. Phase II randomized clinical trial of endosonography and PET/CT versus clinical assessment only for follow-up after surgery for upper gastrointestinal cancer (EUFURO study) (Abstract)

Phase II randomized clinical trial of endosonography and PET/CT versus clinical assessment only for follow-up after surgery for upper gastrointestinal cancer (EUFURO study) Upper gastrointestinal malignancies have a poor prognosis. There is no consensus on how patients should be followed after surgery. The authors hypothesized that a structured follow-up programme including endoscopic ultrasonography (EUS) and [18 F]fluorodeoxyglucose (FDG) PET/CT would detect cancer recurrences, leading (...) chemotherapy (P = 0·028). Although survival after detection of recurrence in asymptomatic patients was significantly longer than that for symptomatic patients (P < 0·001), overall survival from date of surgery in the two treatment groups was comparable.Follow-up after surgery for upper gastrointestinal cancer with EUS and PET/CT leads to detection of more asymptomatic cancer recurrences and patients referred for treatment without prolonging overall survival. Registration number: NCT02209415 ( http

2019 EvidenceUpdates