Latest & greatest articles for constipation

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on constipation or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on constipation and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for constipation

41. Transcutaneous electrical stimulation (TES) for treatment of constipation in children. Full Text available with Trip Pro

Transcutaneous electrical stimulation (TES) for treatment of constipation in children. Childhood constipation is a common problem with substantial health, economic and emotional burdens. Existing therapeutic options, mainly pharmacological, are not consistently effective, and some are associated with adverse effects after prolonged use. Transcutaneous electrical stimulation (TES), a non-pharmacological approach, is postulated to facilitate bowel movement by modulating the nerves of the large (...) bowel via the application of electrical current transmitted through the abdominal wall.Our main objective was to evaluate the effectiveness and safety of TES when employed to improve bowel function and constipation-related symptoms in children with constipation.We searched MEDLINE (PubMed) (1950 to July 2015), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, Issue 7, 2015), EMBASE (1980 to July 2015), the Cochrane IBD Group Specialized Register, trial registries

2016 Cochrane

42. WITHDRAWN: Transcutaneous electrical stimulation (TES) for treatment of constipation in children. Full Text available with Trip Pro

WITHDRAWN: Transcutaneous electrical stimulation (TES) for treatment of constipation in children. Childhood constipation is a common problem with substantial health, economic and emotional burdens. Existing therapeutic options, mainly pharmacological, are not consistently effective, and some are associated with adverse effects after prolonged use. Transcutaneous electrical stimulation (TES), a non-pharmacological approach, is postulated to facilitate bowel movement by modulating the nerves (...) of the large bowel via the application of electrical current transmitted through the abdominal wall.Our main objective was to evaluate the effectiveness and safety of TES when employed to improve bowel function and constipation-related symptoms in children with constipation.We searched MEDLINE (PubMed) (1950 to July 2015), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, Issue 7, 2015), EMBASE (1980 to July 2015), the Cochrane IBD Group Specialized Register, trial

2016 Cochrane

43. Prucalopride (Resolor) and chronic constipation in men

Prucalopride (Resolor) and chronic constipation in men Prescrire IN ENGLISH - Spotlight ''In the October issue of Prescrire International: Prucalopride (Resolor°) and chronic constipation in men'', 1 October 2016 {1} {1} {1} | | > > > In the October issue of Prescrire International: Prucalopride (Resolor°) and chronic constipation in men Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |    (...) |   |   |  Spotlight In the October issue of Prescrire International: Prucalopride (Resolor°) and chronic constipation in men FREE DOWNLOAD For men presenting with constipation, a troublesome but usually benign disorder, prucalopride carries a disproportionate risk of cardiovascular disorders, depression and suicidal ideation. As in women, it is better to optimise the use of standard laxatives, and to avoid prucalopride altogether. Full text available for free download. Summary

2016 Prescrire

44. Acupuncture for Chronic Severe Functional Constipation: A Randomized, Controlled Trial. (Abstract)

Acupuncture for Chronic Severe Functional Constipation: A Randomized, Controlled Trial. Acupuncture has been used for chronic constipation, but evidence for its effectiveness remains scarce.To determine the efficacy of electroacupuncture (EA) for chronic severe functional constipation (CSFC).Randomized, parallel, sham-controlled trial. (ClinicalTrials.gov: NCT01726504).15 hospitals in China.Patients with CSFC and no serious underlying pathologic cause for constipation.28 sessions of EA

2016 Annals of Internal Medicine Controlled trial quality: predicted high

45. Transcutaneous electrical stimulation (TES) for treatment of constipation in children. Full Text available with Trip Pro

Transcutaneous electrical stimulation (TES) for treatment of constipation in children. Childhood constipation is a common problem with substantial health, economic and emotional burdens. Existing therapeutic options, mainly pharmacological, are not consistently effective, and some are associated with adverse effects after prolonged use. Transcutaneous electrical stimulation (TES), a non-pharmacological approach, is postulated to facilitate bowel movement by modulating the nerves of the large (...) bowel via the application of electrical current transmitted through the abdominal wall.Our main objective was to evaluate the effectiveness and safety of TES when employed to improve bowel function and constipation-related symptoms in children with constipation.We searched MEDLINE (PubMed) (1950 to July 2015), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, Issue 7, 2015), EMBASE (1980 to July 2015), the Cochrane IBD Group Specialized Register, trial registries

2016 Cochrane

46. Naldemedine for opioid-induced constipation in adults

Naldemedine for opioid-induced constipation in adults Naldemedine for opioid-induced constipation in adults Naldemedine for opioid-induced constipation in adults NIHR HSRIC Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation NIHR HSRIC. Naldemedine for opioid-induced constipation in adults. Birmingham: NIHR Horizon Scanning Research&Intelligence Centre. Horizon (...) Scanning Review. 2016 Authors' conclusions Opioids are a class of drugs that are commonly prescribed for pain. Constipation is a side effect that affects nearly all patients taking opioid treatment. There has been an increase in the use of opioids to treat chronic pain in recent years. Current treatment for opioid-induced constipation often involves laxatives. But, it has been estimated that 50–80% of people taking laxatives for opioid-induced constipation get only a limited improvement in symptoms

2016 Health Technology Assessment (HTA) Database.

47. Linaclotide for Constipation: Clinical and Cost-Effectiveness

Linaclotide for Constipation: Clinical and Cost-Effectiveness Linaclotide for Constipation: Clinical and Cost-Effectiveness | CADTH.ca Find the information you need Linaclotide for Constipation: Clinical and Cost-Effectiveness Linaclotide for Constipation: Clinical and Cost-Effectiveness Published on: June 21, 2016 Project Number: RA0852-000 Product Line: Research Type: Drug Report Type: Reference List Result type: Report Question What is the clinical effectiveness of linaclotide (...) for the treatment of patients with chronic idiopathic constipation? What is the clinical effectiveness of linaclotide for the treatment of patients with irritable bowel syndrome with constipation? What is the cost-effectiveness of linaclotide for the treatment of patients with chronic idiopathic constipation What is the cost-effectiveness of linaclotide for the treatment of patients with irritable bowel syndrome with constipation? Key Message Eight systematic reviews, three randomized controlled trials, six non

2016 Canadian Agency for Drugs and Technologies in Health - Rapid Review

48. Prucalopride (Resolor) - chronic constipation in men

Prucalopride (Resolor) - chronic constipation in men Final Appraisal Recommendation Advice No: 0816 – March 2016 Prucalopride (Resolor ® ) 1 mg and 2 mg film-coated tablets Limited submission by Shire Pharmaceutical Contracts Ltd Additional note(s): • Please refer to the recommended NICE Technology Appraisal 211 for prucalopride use in women. • Please refer to the Summary of Product Characteristics for the full licensed indication. In reaching the above recommendation AWMSG has taken account (...) . Statement of use: No part of this recommendation may be reproduced without the whole recommendation being quoted in full and cited as: All Wales Medicines Strategy Group. Final Appraisal Recommendation – 0816: Prucalopride (Resolor ® ) 1 mg and 2 mg film-coated tablets. March 2016. Recommendation of AWMSG Prucalopride (Resolor ® ) is recommended as an option for use within NHS Wales for the treatment of chronic constipation in men in whom laxatives fail to provide adequate relief.

2016 All Wales Medicines Strategy Group

49. Easing the strain: put your feet up for constipation

Easing the strain: put your feet up for constipation Easing the strain: put your feet up for constipation - Evidently Cochrane Search and hit Go By February 24, 2016 // In this guest blog, pelvic physiotherapist and comedian Elaine Miller tells us what we need to know to avoid constipation and when the going gets tough. This is the third blog in our new series Evidence for Everyday Health Choices. Constipation is a miserable condition which can worsen co-morbidities like low back pain, muscle (...) can cause constipation, particularly in children – it’s best to move your bowels when you feel the first urge. Poo position You can help reduce the stress on the tissues and reduce straining by squatting to pass a bowel movement. This position encourages the pelvic floor to relax. This can be mimicked on a Western style toilet by raising the feet on a low stool. A stool stool, if you will. Sitting with hips at 90 degrees means the puborectalis muscle is not relaxed, which means the kink

2016 Evidently Cochrane

50. Evaluation and Management of Constipation

Evaluation and Management of Constipation Copyright © The American Society of Colon & Rectal Surgeons, Inc. Unauthorized reproduction of this article is prohibited. 479 Diseases of the Colon & ReCtum Volume 59: 6 (2016) t he a merican s ociety of Colon and Rectal surgeons is dedicated to assuring high-quality patient care by advancing the science, prevention, and manage- ment of disorders and diseases of the colon, rectum, and anus. t he Clinical Practice Guidelines Committee is com- posed (...) specific procedure must be made by the physician in light of all of the cir- cumstances presented by the individual patient. STATEMENT OF THE PROBLEM Constipation is a benign condition that can have a signifi- cant impact on quality of life. t he prevalence has been es- timated to be as high as 30% in select populations and has been noted to be higher in women, nonwhites, those aged >65 years, and those with lower socioeconomic status. 1–6 Constipation is characterized by dysfunction of colonic

2016 American Society of Colon and Rectal Surgeons

51. Constipation in older adults: Stepwise approach to keep things moving

Constipation in older adults: Stepwise approach to keep things moving Constipation in older adults | The College of Family Physicians of Canada Main menu User menu Search Search for this keyword Search for this keyword Research Article Practice Constipation in older adults Stepwise approach to keep things moving Brenda G. Schuster , Lynette Kosar and Rejina Kamrul Canadian Family Physician February 2015, 61 (2) 152-158; Brenda G. Schuster Clinical Pharmacist in the Academic Family Medicine Unit (...) , Regina Division, at the University of Saskatchewan, and Academic Detailer for the RxFiles Academic Detailing Program. Lynette Kosar Clinical Pharmacist for the RxFiles Academic Detailing Program. Rejina Kamrul Assistant Professor in the Academic Family Medicine Unit, Regina Division. Constipation is a common complaint and challenge for older adults. The prevalence of constipation increases with age and differs among settings. In individuals 65 years of age or older in the community, the prevalence

2016 RxFiles

52. Constipation

Constipation Scottish Palliative Care Guidelines - Constipation Scottish Palliative Care Guidelines search / / / Constipation Constipation Introduction Constipation is the passage of small, hard faeces infrequently or with difficulty, and less often than is normal for that individual. Constipation can cause unpleasant symptoms such as abdominal and rectal pain, distension, and other negative effects on the patient’s wellbeing. As well as the physical suffering, constipation can cause (...) psychological distress and agitation in the terminally ill patient. There are many reasons why palliative care patients may develop constipation and these are discussed below. Constipation can be complex and may require specialist advice if the current treatment regime is not successful. Assessment A full assessment of the patient and their symptoms should be obtained looking at: normal and current bowel pattern (frequency, consistency, ease of passage, blood present, pain on passing stool) current

2016 Scottish Palliative Care Guidelines

53. Palliative care - constipation

Palliative care - constipation Palliative care - constipation - NICE CKS Share Palliative care - constipation: Summary Constipation is defecation that is unsatisfactory because of infrequent stools, difficult stool passage, or seemingly incomplete defecation. Stools are often dry and hard, and may be abnormally large or abnormally small. About 80% of people with cancer will require treatment with laxatives at some time. People receiving palliative care have multiple causes of constipation (...) , such as: Drugs, for example, opioid analgesics, antimuscarinic drugs, antacids. Secondary effects of disease, for example, dehydration, inadequate dietary fibre, inactivity, delirium, spinal cord compression, lack of privacy. Direct effects of malignant tumours, causing bowel obstruction, hypercalcaemia, nerve damage. When assessing a person with constipation in palliative care: The history should include information about the frequency and character of stools, discomfort, blood or mucus with the stool

2016 NICE Clinical Knowledge Summaries

54. Interventions for treating constipation in pregnancy. (Abstract)

Interventions for treating constipation in pregnancy. Constipation is a common symptom experienced during pregnancy. It has a range of consequences from reduced quality of life and perception of physical health to haemorrhoids. An understanding of the effectiveness and safety of treatments for constipation in pregnancy is important for the clinician managing pregnant women.To assess the effectiveness and safety of interventions (pharmacological and non-pharmacological) for treating constipation (...) in pregnancy.We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (30 April 2015), ClinicalTrials.gov and the WHO International Clinical Trials Registry Platform (ICTRP) (30 April 2015) and reference lists of retrieved studies.We considered all published, unpublished and ongoing randomised controlled trials (RCTs), cluster-RCTs and quasi-RCTs, evaluating interventions (pharmacological and non-pharmacological) for constipation in pregnancy. Cross-over studies were not eligible

2015 Cochrane

55. Linaclotide (Constella) in the symptomatic management of irritable bowel syndrome with constipation, The indication was granted...so what?

Linaclotide (Constella) in the symptomatic management of irritable bowel syndrome with constipation, The indication was granted...so what? 2015. DAR No 4: Linaclotide. Constella® in the symptomatic management of irritable bowel syndrome with constipation - navarra.es Castellano | Euskara | Français | English Use the search tool! Search engine : : : : : : DAR No 4: Linaclotide. Constella® in the symptomatic management of irritable bowel syndrome with constipation DAR No 4: Linaclotide. Constella (...) ® in the symptomatic management of irritable bowel syndrome with constipation Content tools Share it The indication was granted...so what? Although authorized for irritable bowel syndrome with constipation it offers only symptomatic relief. In the best of cases, one in five patients can benefit from treatment. On the other hand, one in five patients can suffer from diarrhea as a secondary effect which can last for more than 28 days in half the cases. There are no available studies evaluating

2015 Drug and Therapeutics Bulletin of Navarre (Spain)

56. Sacral nerve stimulation for faecal incontinence and constipation in adults. Full Text available with Trip Pro

Sacral nerve stimulation for faecal incontinence and constipation in adults. Faecal incontinence (FI) and constipation are both socially-embarrassing and physically-disabling conditions that impair quality of life. For both, surgery may be required in a minority of people when more conservative measures fail. However, the invasiveness and irreversible nature of direct surgery on bowel and sphincter muscles, poor long-term outcomes and well-established compIications makes such procedures (...) unappealing for these benign conditions. A less-invasive surgical option to treat faecal incontinence and constipation is direct, low-voltage stimulation of the sacral nerve roots, termed sacral nerve stimulation (SNS). SNS has become the first line surgical treatment for FI in people failing conservative therapies. Its value in the treatment of constipation is less clear.To assess the effects of sacral nerve stimulation using implanted electrodes for the treatment of faecal incontinence and constipation

2015 Cochrane

57. Constipation Associated with a Lipoma. (Abstract)

Constipation Associated with a Lipoma. 26267625 2015 08 20 2016 11 25 1533-4406 373 7 2015 Aug 13 The New England journal of medicine N. Engl. J. Med. IMAGES IN CLINICAL MEDICINE. Constipation Associated with a Lipoma. 656 10.1056/NEJMicm1413283 Hardy C Lamar CL Naval Medical Center Portsmouth, Portsmouth, VA curtis.hardy@me.com. Goliath Gilbert G eng Case Reports Journal Article United States N Engl J Med 0255562 0028-4793 AIM IM Adolescent Constipation etiology Female Humans Intestinal

2015 NEJM

58. Naloxegol for treating opioid-induced constipation

Naloxegol for treating opioid-induced constipation Nalo Nalox xegol for treating opioid-induced egol for treating opioid-induced constipation constipation T echnology appraisal guidance Published: 22 July 2015 nice.org.uk/guidance/ta345 © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guidance represent the view of NICE, arrived at after careful (...) a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Naloxegol for treating opioid-induced constipation (TA345) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 43Contents Contents 1 Guidance 4 2 The technology 5 3 The company's submission 6 Clinical effectiveness 6 Evidence Review

2015 National Institute for Health and Clinical Excellence - Technology Appraisals

59. Polyethylene Glycol for the Treatment of Constipation in Patients in Acute and Long-Term Care: Cost-Effectiveness and Guidelines

Polyethylene Glycol for the Treatment of Constipation in Patients in Acute and Long-Term Care: Cost-Effectiveness and Guidelines Polyethylene Glycol for the Treatment of Constipation in Patients in Acute and Long-Term Care: Cost-Effectiveness and Guidelines | CADTH.ca Find the information you need Polyethylene Glycol for the Treatment of Constipation in Patients in Acute and Long-Term Care: Cost-Effectiveness and Guidelines Polyethylene Glycol for the Treatment of Constipation in Patients (...) in Acute and Long-Term Care: Cost-Effectiveness and Guidelines Published on: July 14, 2015 Project Number: RA0785-000 Product Line: Report Type: Reference List Result type: Report Question What is the cost-effectiveness of polyethylene glycol for the treatment of constipation in adults in acute or long-term care? What is the cost-effectiveness of polyethylene glycol for the treatment of constipation in children in acute or long-term care? What are the evidence-based guidelines regarding the use

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

60. Peristeen Anal Irrigation System for the Management of Incontinence and Constipation in Patients with VACTERL Association: Clinical Effectiveness and Cost-Effectiveness

Peristeen Anal Irrigation System for the Management of Incontinence and Constipation in Patients with VACTERL Association: Clinical Effectiveness and Cost-Effectiveness Peristeen Anal Irrigation System for the Management of Incontinence and Constipation in Patients with VACTERL Association: Clinical Effectiveness and Cost-Effectiveness | CADTH.ca Find the information you need Peristeen Anal Irrigation System for the Management of Incontinence and Constipation in Patients with VACTERL (...) Association: Clinical Effectiveness and Cost-Effectiveness Peristeen Anal Irrigation System for the Management of Incontinence and Constipation in Patients with VACTERL Association: Clinical Effectiveness and Cost-Effectiveness Published on: July 7, 2015 Project Number: RA0779-000 Product Line: Research Type: Devices and Systems Report Type: Reference List Result type: Report Question What is the clinical effectiveness of the Peristeen anal irrigation system for the management of incontinence

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review