Latest & greatest articles for corticosteroids

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Top results for corticosteroids

361. Randomized trial of pulsed corticosteroid therapy for primary treatment of Kawasaki disease. (Abstract)

Randomized trial of pulsed corticosteroid therapy for primary treatment of Kawasaki disease. Treatment of acute Kawasaki disease with intravenous immune globulin and aspirin reduces the risk of coronary-artery abnormalities and systemic inflammation, but despite intravenous immune globulin therapy, coronary-artery abnormalities develop in some children. Studies have suggested that primary corticosteroid therapy might be beneficial and that adverse events are infrequent with short-term use.We

2007 NEJM Controlled trial quality: predicted high

362. Outcomes at 2 years of age after repeat doses of antenatal corticosteroids. Full Text available with Trip Pro

Outcomes at 2 years of age after repeat doses of antenatal corticosteroids. We previously reported the results of a randomized, controlled trial showing that repeat doses of antenatal corticosteroids reduced the risk of respiratory distress syndrome and serious neonatal morbidity. However, data have not been available regarding longer-term effects of this treatment.Women who had received an initial course of corticosteroid treatment 7 or more days previously were randomly assigned to receive (...) an intramuscular injection of corticosteroid (11.4 mg of betamethasone) or saline placebo; the dose was repeated weekly if the mother was still considered to be at risk for preterm delivery and the duration of gestation was less than 32 weeks. We assessed survival free of major neurosensory disability and body size of the children at 2 years of corrected age.Of the 1085 children who were alive at 2 years of age, 1047 (96.5%) were seen for assessment (521 exposed to repeat-corticosteroid treatment and 526

2007 NEJM Controlled trial quality: predicted high

363. Long-term outcomes after repeat doses of antenatal corticosteroids. (Abstract)

Long-term outcomes after repeat doses of antenatal corticosteroids. Previous trials have shown that repeat courses of antenatal corticosteroids improve some neonatal outcomes in preterm infants but reduce birth weight and increase the risk of intrauterine growth restriction. We report long-term follow-up results of children enrolled in a randomized trial comparing single and repeat courses of antenatal corticosteroids.Women at 23 through 31 weeks of gestation who remained pregnant 7 days after (...) an initial course of corticosteroids were randomly assigned to weekly courses of betamethasone, consisting of 12 mg given intramuscularly and repeated once at 24 hours, or an identical-appearing placebo. We studied the children who were born after these treatments when they were between 2 and 3 years of corrected age. Prespecified outcomes included scores on the Bayley Scales of Infant Development, anthropometric measurements, and the presence of cerebral palsy.A total of 556 infants were available

2007 NEJM Controlled trial quality: predicted high

364. Combination therapy with the single inhaler salmeterol/fluticasone propionate versus increased doses of inhaled corticosteroids in patients with asthma

Combination therapy with the single inhaler salmeterol/fluticasone propionate versus increased doses of inhaled corticosteroids in patients with asthma Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2007 DARE.

365. Corticosteroid injections in the treatment of trigger finger: a level I and II systematic review

. Funding Vanderbilt Sports Medicine Research Fund. Bibliographic details Fleisch S B, Spindler K P, Lee D H. Corticosteroid injections in the treatment of trigger finger: a level I and II systematic review. Journal of the American Academy of Orthopaedic Surgeons 2007; 15(3): 166-171 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Adrenal Cortex Hormones /administration & Evidence-Based Medicine; Humans; Randomized Controlled Trials as Topic; Trigger Finger Disorder /drug therapy; dosage (...) Corticosteroid injections in the treatment of trigger finger: a level I and II systematic review Corticosteroid injections in the treatment of trigger finger: a level I and II systematic review Corticosteroid injections in the treatment of trigger finger: a level I and II systematic review Fleisch S B, Spindler K P, Lee D H CRD summary The authors concluded that corticosteroid use was associated with an improvement in symptoms in 57% of patients. Limitations in the literature search, the poor

2007 DARE.

366. The efficacy of subacromial corticosteroid injection in the treatment of rotator cuff disease: a systematic review

. The efficacy of subacromial corticosteroid injection in the treatment of rotator cuff disease: a systematic review. Journal of the American Academy of Orthopaedic Surgeons 2007; 15(1): 3-11 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Adrenal Cortex Hormones /therapeutic use; Evidence-Based Medicine; Humans; Injections, Intra-Articular; Pain Measurement; Randomized Controlled Trials as Topic; Range of Motion, Articular; Rotator Cuff /physiopathology; Shoulder Pain /drug therapy (...) The efficacy of subacromial corticosteroid injection in the treatment of rotator cuff disease: a systematic review The efficacy of subacromial corticosteroid injection in the treatment of rotator cuff disease: a systematic review The efficacy of subacromial corticosteroid injection in the treatment of rotator cuff disease: a systematic review Koester M C, Dunn W R, Kuhn J E, Spindler K P CRD summary The authors of this review found that there was little reproducible evidence to support

2007 DARE.

367. Effects of corticosteroid on Henoch-Schonlein purpura: a systematic review

Effects of corticosteroid on Henoch-Schonlein purpura: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2007 DARE.

368. Shoulder adhesive capsulitis: systematic review of randomised trials using multiple corticosteroid injections

. Bibliographic details Shah N, Lewis M. Shoulder adhesive capsulitis: systematic review of randomised trials using multiple corticosteroid injections. British Journal of General Practice 2007; 57: 662-667 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Adrenal Cortex Hormones /administration & Adult; Bursitis /drug therapy /physiopathology; Humans; Injections, Intra-Articular; Randomized Controlled Trials as Topic; Range of Motion, Articular /physiology; Shoulder Joint /physiopathology (...) Shoulder adhesive capsulitis: systematic review of randomised trials using multiple corticosteroid injections Shoulder adhesive capsulitis: systematic review of randomised trials using multiple corticosteroid injections Shoulder adhesive capsulitis: systematic review of randomised trials using multiple corticosteroid injections Shah N, Lewis M CRD summary This review concluded that multiple corticosteroid injections for the treatment of adhesive capsulitis of the shoulder improved pain

2007 DARE.

369. Corticosteroid treatment of severe community-acquired pneumonia Full Text available with Trip Pro

treatment of severe community-acquired pneumonia. Research : The authors did not state any implications for research. Funding Not stated. Bibliographic details Gorman S K, Slavik R S, Marin J. Corticosteroid treatment of severe community-acquired pneumonia. Annals of Pharmacotherapy 2007; 41(7-8): 1233-1237 PubMedID DOI Original Paper URL Indexing Status Subject indexing assigned by NLM MeSH Adrenal Cortex Hormones /pharmacokinetics /therapeutic use; Community-Acquired Infections /blood /drug therapy (...) Corticosteroid treatment of severe community-acquired pneumonia Corticosteroid treatment of severe community-acquired pneumonia Corticosteroid treatment of severe community-acquired pneumonia Gorman S K, Slavik R S, Marin J CRD summary This review aimed to assess the evidence for adjunctive corticosteroids on the treatment of severe community-acquired pneumonia. The authors concluded that, given the paucity of information on their effects, systemic corticosteroids could not be recommended

2007 DARE.

370. Meta-analysis technique confirms the effectiveness of anti-TNF-alpha in the management of active ulcerative colitis when administered in combination with corticosteroids

of active ulcerative colitis when administered in combination with corticosteroids. Medical Science. Monitor 2007; 13(7): PI13-PI18 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Adrenal Cortex Hormones /therapeutic use; Adult; Anti-Inflammatory Agents /therapeutic use; Antibodies, Monoclonal /therapeutic use; Colitis, Ulcerative /therapy; Female; Humans; Infliximab; Male; Models, Biological; Odds Ratio; Placebos; Randomized Controlled Trials as Topic; Remission Induction; Treatment (...) Meta-analysis technique confirms the effectiveness of anti-TNF-alpha in the management of active ulcerative colitis when administered in combination with corticosteroids Meta-analysis technique confirms the effectiveness of anti-TNF-alpha in the management of active ulcerative colitis when administered in combination with corticosteroids Meta-analysis technique confirms the effectiveness of anti-TNF-alpha in the management of active ulcerative colitis when administered in combination

2007 DARE.

371. Impact of inhaled corticosteroid-induced oropharyngeal adverse events: results from a meta-analysis

. Cicutto L. Review: inhaled corticosteroids increase risk of oral candidiasis, dysphonia, and pharyngitis in persistent asthma. Evid Based Nurs 2007;10:109. Indexing Status Subject indexing assigned by NLM MeSH Administration, Inhalation; Adrenal Cortex Hormones /adverse effects /therapeutic use; Candidiasis, Oral /chemically induced /etiology; Double-Blind Method; Metered Dose Inhalers /adverse effects; Oropharynx /drug effects; Pharyngitis /chemically induced /etiology; Randomized Controlled Trials (...) Impact of inhaled corticosteroid-induced oropharyngeal adverse events: results from a meta-analysis Impact of inhaled corticosteroid-induced oropharyngeal adverse events: results from a meta-analysis Impact of inhaled corticosteroid-induced oropharyngeal adverse events: results from a meta-analysis Rachelefsky G S, Liao Y, Faruqi R CRD summary This review assessed oropharyngeal adverse events associated with corticosteroid inhalation in participants with persistent asthma. The authors concluded

2007 DARE.

372. Non-Hodgkin's lymphoma: meta-analyses of the effects of corticosteroids and non-steroidal anti-inflammatories

Non-Hodgkin's lymphoma: meta-analyses of the effects of corticosteroids and non-steroidal anti-inflammatories Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2007 DARE.

373. Response to corticosteroids in severe ulcerative colitis: a systematic review of the literature and a meta-regression

Response to corticosteroids in severe ulcerative colitis: a systematic review of the literature and a meta-regression Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2007 DARE.

374. Long-acting Beta2-agonists (LABA) plus corticosteroids versus LABA alone for chronic obstructive pulmonary disease

-effective by those who are prepared to pay up to 50,000 Canadian dollars for a QALY. : CT requires additional resources. Switching all patients who are >65 years old and only receive a LABA without an ICS to CT treatment would require, by extrapolation, an additional 3.3 million Canadian dollars in Alberta, and 43.7 million Canadian dollars nationally. Project page URL INAHTA brief and checklist Indexing Status Subject indexing assigned by CRD MeSH Adrenal Cortex Hormones /therapeutic use; Adrenergic (...) Long-acting Beta2-agonists (LABA) plus corticosteroids versus LABA alone for chronic obstructive pulmonary disease Long-acting Beta2-agonists (LABA) plus corticosteroids versus LABA alone for chronic obstructive pulmonary disease Long-acting Beta2-agonists (LABA) plus corticosteroids versus LABA alone for chronic obstructive pulmonary disease Brady B, Siebert U, Sroczynski G, Murphy G, Husereau D, Sherman M, Wong W, Mensinkai S Record Status This is a bibliographic record of a published health

2007 Health Technology Assessment (HTA) Database.

375. Overview of long-acting Beta2-agonists (LABA) plus corticosteroids versus LABA alone for chronic obstructive pulmonary disease

Status Subject indexing assigned by CRD MeSH Adrenal Cortex Hormones /therapeutic use; Adrenergic beta-Agonists /therapeutic use; Pulmonary Disease, Chronic Obstructive /drug therapy Language Published English Country of organisation Canada Province or state Ontario Address for correspondence 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392; Email: publications@cadth.ca AccessionNumber 32007000132 Date bibliographic record published 30/03/2007 Date (...) Overview of long-acting Beta2-agonists (LABA) plus corticosteroids versus LABA alone for chronic obstructive pulmonary disease Overview of long-acting Beta2-agonists (LABA) plus corticosteroids versus LABA alone for chronic obstructive pulmonary disease Overview of long-acting Beta2-agonists (LABA) plus corticosteroids versus LABA alone for chronic obstructive pulmonary disease Brady B, Siebert U, Sroczynski G, Murphy G, Husereau D, Sherman M, Wong W, Mensinkai S Record Status

2007 Health Technology Assessment (HTA) Database.

376. Fixed combinations of corticosteroids and long-acting beta-2-receptor agonists for inhaled use in patients with asthma

by separate inhalers in children. Project page URL Indexing Status Subject indexing assigned by CRD MeSH Adrenal Cortex Hormones /therapeutic use; Anti-Asthmatic Agents /therapeutic use; Asthma /drug therapy Language Published German Country of organisation Germany English Summary English summary available Address for correspondence Dillenburger Str. 27, DE-51105 Cologne, GERMANY, Tel: +49 221 356856, Fax: +49 221 35685 804 Email: info@iqwig.de AccessionNumber 32007000439 Date bibliographic record (...) Fixed combinations of corticosteroids and long-acting beta-2-receptor agonists for inhaled use in patients with asthma Fixed combinations of corticosteroids and long-acting beta-2-receptor agonists for inhaled use in patients with asthma Fixed combinations of corticosteroids and long-acting beta-2-receptor agonists for inhaled use in patients with asthma Institut fuer Qualitaet und Wirtschaftlichkeit im Gesundheitswesen Record Status This is a bibliographic record of a published health

2007 Health Technology Assessment (HTA) Database.

377. Corticosteroids for bacterial meningitis in adults in sub-Saharan Africa. Full Text available with Trip Pro

Corticosteroids for bacterial meningitis in adults in sub-Saharan Africa. In sub-Saharan Africa, bacterial meningitis is common and is associated with a high mortality. Adjuvant therapy with corticosteroids reduces mortality among adults in the developed world, but it has not been adequately tested in developing countries or in the context of advanced human immunodeficiency virus (HIV) infection.We conducted a randomized, double-blind, placebo-controlled trial of dexamethasone (16 mg twice (...) ). There was no significant difference in mortality at 40 days in the corticosteroid group (129 of 231 patients) as compared with the placebo group (120 of 228 patients) by intention-to-treat analysis (odds ratio, 1.14; 95% confidence interval [CI], 0.79 to 1.64) or when the analysis was restricted to patients with proven pneumococcal meningitis (68 of 129 patients receiving corticosteroids vs. 72 of 143 patients receiving placebo) (odds ratio, 1.10; 95% CI, 0.68 to 1.77). There were no significant differences between

2007 NEJM Controlled trial quality: predicted high

378. Cost-effectiveness and healthcare budget impact in Italy of inhaled corticosteroids and brochodilators for severe and very severe COPD patients

Suppl C:S43-S50. Lucioni C, Donner CF, De Benedetto F, et al. I costi della broncopneumopatia cronica ostruttiva : la fase prospettica dello studio ICE (Italian Costs for Exacerbations in COPD). Pharmacoeconomics 2005;7:119-34. Indexing Status Subject indexing assigned by NLM MeSH Administration, Inhalation; Adrenal Cortex Hormones /administration & Albuterol /analogs & Androstadienes /economics /therapeutic use; Bronchodilator Agents /administration & Budesonide /economics /therapeutic use; Budgets (...) Cost-effectiveness and healthcare budget impact in Italy of inhaled corticosteroids and brochodilators for severe and very severe COPD patients Cost-effectiveness and healthcare budget impact in Italy of inhaled corticosteroids and brochodilators for severe and very severe COPD patients Cost-effectiveness and healthcare budget impact in Italy of inhaled corticosteroids and brochodilators for severe and very severe COPD patients Dal Negro R, Eandi M, Pradelli L, Iannazzo S Record Status

2007 NHS Economic Evaluation Database.

379. Safety and effectiveness of long-acting inhaled beta-agonist bronchodilators when taken with inhaled corticosteroids. (Abstract)

Safety and effectiveness of long-acting inhaled beta-agonist bronchodilators when taken with inhaled corticosteroids. Long-acting beta-agonists are a pillar of therapy for many patients with asthma because they are the preferred add-on therapy to inhaled corticosteroids. However, a recent meta-analysis documented a substantial increase in severe exacerbations requiring hospital admission and life-threatening asthma exacerbations in patients treated with long-acting beta-agonists. A careful (...) evaluation of this meta-analysis raises several concerns about its applicability to current practice. Pivotal trials evaluating the benefit of adding long-acting beta-agonists to inhaled corticosteroids were not included. The authors of the current paper call for physicians to continue their usual practice of using long-acting beta-agonists as adjunctive therapy, as well as for an independent meta-analysis of individual patients using inhaled corticosteroids and long-acting beta-agonists concomitantly.

2006 Annals of Internal Medicine

380. Corticosteroids for viral myocarditis. (Abstract)

Corticosteroids for viral myocarditis. Myocarditis is an uncommon heart disease. There is experimental evidence showing that autoimmune mechanisms follow viral infection, resulting in inflammation and necrosis in myocardium. However, the use of corticosteroids as immunosuppressives in this condition remains controversial.To assess the beneficial and harmful effects of treating viral myocarditis with corticosteroids.Trials were identified by searching The Cochrane Heart Group Register (to April (...) 2004), the Cochrane Library (Issue 4, 2003), and MEDLINE, EMBASE, BIOSIS for meeting abstracts, LILACS, and Chinese Biomedical CD Database from their date of inception to April 20, 2004. Four Chinese medical journals were handsearched. A total of 507 articles were found but none of them was eligible to be included in our review.Randomised controlled trials of corticosteroids for viral myocarditis compared with no intervention, placebo, supportive therapy, antiviral agents therapy or conventional

2006 Cochrane