Latest & greatest articles for corticosteroids

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Top results for corticosteroids

381. Corticosteroids for treating dengue shock syndrome. (Abstract)

Corticosteroids for treating dengue shock syndrome. Dengue shock syndrome is the most severe from of dengue haemorrhagic fever, one of the leading causes of death in children. Observational studies have suggested corticosteroids may benefit people with dengue shock syndrome.To compare corticosteroids with placebo or no corticosteroids for treating dengue shock syndrome.We searched the Cochrane Infectious Disease Group Specialized Register (January 2006), CENTRAL (The Cochrane Library 2005 (...) , Issue 4), MEDLINE (1966 to January 2006), EMBASE, (1974 to January 2006), LILACS (1982 to January 2006), and reference lists. We also contacted researchers.Randomized and quasi-randomized controlled trials comparing corticosteroids with no corticosteroids or placebo in people diagnosed with dengue shock syndrome.Two authors independently applied the inclusion criteria, extracted data, and assessed methodological quality. We calculated the relative risk (RR) for dichotomous data and weighted mean

2006 Cochrane

382. Parent-initiated oral corticosteroid therapy for intermittent wheezing illnesses in children. (Abstract)

Parent-initiated oral corticosteroid therapy for intermittent wheezing illnesses in children. Intermittent wheezing illnesses, which include viral associated wheeze and asthma, are amongst the most common reasons for children to present urgently to a doctor. Whether parents should commence oral corticosteroids (OCS) for an episode of acute wheeze in their child without waiting for a medical review is an important question, as the potential benefits of early oral corticosteroid intervention have

2006 Cochrane

383. Corticosteroids for cervical ripening and induction of labour. (Abstract)

Corticosteroids for cervical ripening and induction of labour. The role of corticosteroids in the process of labour is not well understood. Animal studies have shown the importance of cortisol secretion by the fetal adrenal gland in initiating labour in sheep. Infusion of glucocorticosteroids into the fetus has also shown to induce premature labour in sheep. Given these studies it has been postulated that corticosteroids will promote the induction of labour in women. This is one of a series (...) of reviews of methods of cervical ripening and labour induction using standardised methodology.To determine the effects of corticosteroids for third trimester cervical ripening or induction of labour in comparison with other methods of cervical priming or induction of labour.We searched the Cochrane Pregnancy and Childbirth Group Trials Register (December 2005) and bibliographies of relevant papers.Clinical trials of corticosteroids for third trimester cervical ripening or labour induction.A strategy

2006 Cochrane

384. Review: intra-articular corticosteroid injections are better than placebo for improving symptoms of knee osteoarthritis Full Text available with Trip Pro

Review: intra-articular corticosteroid injections are better than placebo for improving symptoms of knee osteoarthritis Review: intra-articular corticosteroid injections are better than placebo for improving symptoms of knee osteoarthritis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: intra-articular corticosteroid injections are better than placebo for improving symptoms of knee osteoarthritis Article Text Therapeutics Review

2006 Evidence-Based Medicine

385. Review: corticosteroids do not reduce hospital length of stay or respiratory distress in infantile acute viral bronchiolitis Full Text available with Trip Pro

Review: corticosteroids do not reduce hospital length of stay or respiratory distress in infantile acute viral bronchiolitis Review: corticosteroids do not reduce hospital length of stay or respiratory distress in infantile acute viral bronchiolitis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log (...) in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: corticosteroids do not reduce hospital length of stay or respiratory distress in infantile acute viral bronchiolitis Article Text

2006 Evidence-Based Medicine

386. Long-term inhaled corticosteroids in preschool children at high risk for asthma. Full Text available with Trip Pro

Long-term inhaled corticosteroids in preschool children at high risk for asthma. It is unknown whether inhaled corticosteroids can modify the subsequent development of asthma in preschool children at high risk for asthma.We randomly assigned 285 participants two or three years of age with a positive asthma predictive index to treatment with fluticasone propionate (at a dose of 88 mug twice daily) or masked placebo for two years, followed by a one-year period without study medication (...) . The primary outcome was the proportion of episode-free days during the observation year.During the observation year, no significant differences were seen between the two groups in the proportion of episode-free days, the number of exacerbations, or lung function. During the treatment period, as compared with placebo use, use of the inhaled corticosteroid was associated with a greater proportion of episode-free days (P=0.006) and a lower rate of exacerbations (P<0.001) and of supplementary use

2006 NEJM Controlled trial quality: predicted high

387. Intermittent inhaled corticosteroids in infants with episodic wheezing. Full Text available with Trip Pro

Intermittent inhaled corticosteroids in infants with episodic wheezing. We hypothesized that asthma is preceded by a stage of recurrent episodes of wheezing during the first years of life and that inhaled corticosteroid therapy during symptomatic episodes in this early phase may delay progression to persistent wheezing.We assigned one-month-old infants to treatment with two-week courses of inhaled budesonide (400 mug per day) or placebo, initiated after a three-day episode of wheezing (...) and bone mineral density were not affected by treatment.Intermittent inhaled corticosteroid therapy had no effect on the progression from episodic to persistent wheezing and no short-term benefit during episodes of wheezing in the first three years of life. (ClinicalTrials.gov number, NCT00234390.).Copyright 2006 Massachusetts Medical Society.

2006 NEJM Controlled trial quality: predicted high

388. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. (Abstract)

Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. Persistent acute respiratory distress syndrome (ARDS) is characterized by excessive fibroproliferation, ongoing inflammation, prolonged mechanical ventilation, and a substantial risk of death. Because previous reports suggested that corticosteroids may improve survival, we performed a multicenter, randomized controlled trial of corticosteroids in patients with persistent ARDS.We randomly assigned 180

2006 NEJM Controlled trial quality: predicted high

389. Neonatal respiratory distress syndrome after repeat exposure to antenatal corticosteroids: a randomised controlled trial. (Abstract)

Neonatal respiratory distress syndrome after repeat exposure to antenatal corticosteroids: a randomised controlled trial. The efficacy and safety of repeat doses of prenatal corticosteroids remains uncertain. Our aim was to establish whether repeat prenatal corticosteroids given to women at risk of preterm birth can reduce neonatal morbidity without harm.In this hospital-based study, 982 women who remained at risk of preterm birth at less than 32 weeks' gestation, 7 or more days after receiving (...) a first course of prenatal corticosteroids, were randomly assigned to receive a repeat intramuscular dose of either 11.4 mg betamethasone (as Celestone Chronodose), or saline placebo. This was repeated every week the woman remained undelivered, at less than 32 weeks' gestation, and at risk of preterm birth. Primary outcomes were occurrence and severity of neonatal respiratory distress syndrome, use and duration of oxygen and mechanical ventilation, and weight, length, and head circumference at birth

2006 Lancet Controlled trial quality: predicted high

390. Mobilisation with movement and exercise, corticosteroid injection, or wait and see for tennis elbow: randomised trial. Full Text available with Trip Pro

Mobilisation with movement and exercise, corticosteroid injection, or wait and see for tennis elbow: randomised trial. To investigate the efficacy of physiotherapy compared with a wait and see approach or corticosteroid injections over 52 weeks in tennis elbow.Single blind randomised controlled trial.Community setting, Brisbane, Australia.198 participants aged 18 to 65 years with a clinical diagnosis of tennis elbow of a minimum six weeks' duration, who had not received any other active (...) treatment by a health practitioner in the previous six months.Eight sessions of physiotherapy; corticosteroid injections; or wait and see.Global improvement, grip force, and assessor's rating of severity measured at baseline, six weeks, and 52 weeks.Corticosteroid injection showed significantly better effects at six weeks but with high recurrence rates thereafter (47/65 of successes subsequently regressed) and significantly poorer outcomes in the long term compared with physiotherapy. Physiotherapy

2006 BMJ Controlled trial quality: predicted high

391. Rapid effects of inhaled corticosteroids in acute asthma: an evidence-based evaluation Full Text available with Trip Pro

Disease; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones /administration & Adult; Aged; Asthma /drug therapy /physiopathology; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Infant; Middle Aged; Randomized Controlled Trials as Topic; Reproducibility of Results; Time Factors; Treatment Outcome; dosage /therapeutic use AccessionNumber 12006009239 Date bibliographic record published 07/11/2007 Date abstract record published 30/09/2008 (...) Rapid effects of inhaled corticosteroids in acute asthma: an evidence-based evaluation Rapid effects of inhaled corticosteroids in acute asthma: an evidence-based evaluation Rapid effects of inhaled corticosteroids in acute asthma: an evidence-based evaluation Rodrigo G J CRD summary The author concluded that inhaled corticosteroids, in addition to standard treatment, may be beneficial for acute exacerbations of asthma among adults and children. Multiple doses should be administered at least

2006 DARE.

392. Clinical safety of inhaled corticosteroids for asthma in children: an update of long-term trials

MeSH Administration, Inhalation; Adrenal Cortex Hormones /administration & Anti-Asthmatic Agents /administration & Asthma /drug therapy; Body Height /drug effects; Bone Density /drug effects; Child; Clinical Trials as Topic; Humans; Hydrocortisone /metabolism; dosage /adverse effects; dosage /adverse effects AccessionNumber 12006004552 Date bibliographic record published 03/09/2007 Date abstract record published 22/04/2009 Record Status This is a critical abstract of a systematic review that meets (...) studies, n=unclear): All four RCTs reported that inhaled corticosteroid therapy had no effect on BMD. Cortisol levels (10 studies, n=unclear): In general, studies of recommended doses of inhaled corticosteroids found little or no effect on measures of hypothalamic-pituitary-adrenal (HPA) axis function over 12 to 36 months follow-up. Two RCTs compared fluticasone propionate (200 micrograms) against different doses of beclometasone. One study found no difference between fluticasone propionate

2006 DARE.

393. A cost-utility analysis of pimecrolimus vs. topical corticosteroids and emollients for the treatment of mild and moderate atopic eczema

A cost-utility analysis of pimecrolimus vs. topical corticosteroids and emollients for the treatment of mild and moderate atopic eczema A cost-utility analysis of pimecrolimus vs. topical corticosteroids and emollients for the treatment of mild and moderate atopic eczema A cost-utility analysis of pimecrolimus vs. topical corticosteroids and emollients for the treatment of mild and moderate atopic eczema Pitt M, Garside R, Stein K Record Status This is a critical abstract of an economic (...) evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of topical corticosteroids (TCS) as a first-line treatment followed by pimecrolimus as a second-line treatment, and pimecrolimus as a first-line treatment followed by TCS, in the treatment of mild and moderate atopic eczema. Type

2006 NHS Economic Evaluation Database.

394. 2 year inhaled corticosteroid therapy did not prevent asthma in high risk preschool children after treatment was discontinued

2 year inhaled corticosteroid therapy did not prevent asthma in high risk preschool children after treatment was discontinued 2 year inhaled corticosteroid therapy did not prevent asthma in high risk preschool children after treatment was discontinued | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log (...) in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here 2 year inhaled corticosteroid therapy did not prevent asthma in high risk preschool children after treatment was discontinued Article Text

2006 Evidence-Based Medicine

395. Review: adults who require inhaled corticosteroids benefit from a moderate starting dose Full Text available with Trip Pro

Review: adults who require inhaled corticosteroids benefit from a moderate starting dose Review: adults who require inhaled corticosteroids benefit from a moderate starting dose | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers (...) of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: adults who require inhaled corticosteroids benefit from a moderate starting dose Article Text Therapeutics Review: adults who require inhaled corticosteroids benefit from a moderate starting dose Free Frank

2005 Evidence-Based Medicine

396. Doubling the dose of inhaled corticosteroids during asthma deterioration did not improve asthma control Full Text available with Trip Pro

Doubling the dose of inhaled corticosteroids during asthma deterioration did not improve asthma control Doubling the dose of inhaled corticosteroids during asthma deterioration did not improve asthma control | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Doubling the dose of inhaled corticosteroids during asthma deterioration did not improve asthma control Article Text Therapeutics Doubling the dose of inhaled corticosteroids

2005 Evidence-Based Medicine

397. Oral corticosteroids for stable chronic obstructive pulmonary disease. (Abstract)

Oral corticosteroids for stable chronic obstructive pulmonary disease. Chronic obstructive pulmonary disease (COPD) is a common chronic lung disorder, usually related to cigarette smoking, representing a major and increasing cause of morbidity and mortality. It is defined "as a disease state characterized by airflow limitation that is not fully reversible. The airflow limitation is usually both progressive and associated with an abnormal inflammatory response of the lungs to noxious particles (...) or gases". The use of corticosteroids for their anti-inflammatory effects has been suggested.To assess the effects of oral corticosteroids on the health status of patients with stable COPD.Searches of the Cochrane Airways Group Specialised Register and MEDLINE were carried out in December 2003 and 2004. Review articles and bibliographies were searched.Randomised controlled prospective studies in adults with stable COPD ( post-bronchodilator FEV1 <80% of predicted, FEV1/FVC <70%) and a history

2005 Cochrane

398. Smokers and ex-smokers with chronic stable asthma did not respond to high dose oral corticosteroids Full Text available with Trip Pro

Smokers and ex-smokers with chronic stable asthma did not respond to high dose oral corticosteroids Smokers and ex-smokers with chronic stable asthma did not respond to high dose oral corticosteroids | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Smokers and ex-smokers with chronic stable asthma did not respond to high dose oral corticosteroids Article Text Therapeutics Smokers and ex-smokers with chronic stable asthma did

2005 Evidence-Based Medicine

399. Review: long acting B2 agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease Full Text available with Trip Pro

Review: long acting B2 agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease Review: long acting β2 agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: long acting β2 agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease Article Text Treatment Review

2005 Evidence-Based Nursing

400. Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months. (Abstract)

Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months. MRC CRASH is a randomised controlled trial (ISRCTN74459797) of the effect of corticosteroids on death and disability after head injury. We randomly allocated 10,008 adults with head injury and a Glasgow Coma Scale score of 14 or less, within 8 h of injury, to a 48-h infusion of corticosteroid (methylprednisolone) or placebo. Data at 6 months were (...) obtained for 9673 (96.7%) patients. The risk of death was higher in the corticosteroid group than in the placebo group (1248 [25.7%] vs 1075 [22.3%] deaths; relative risk 1.15, 95% CI 1.07-1.24; p=0.0001), as was the risk of death or severe disability (1828 [38.1%] vs 1728 [36.3%] dead or severely disabled; 1.05, 0.99-1.10; p=0.079). There was no evidence that the effect of corticosteroids differed by injury severity or time since injury. These results lend support to our earlier conclusion

2005 Lancet Controlled trial quality: predicted high