Latest & greatest articles for corticosteroids

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Top results for corticosteroids

401. Review: adjuvant corticosteroid therapy reduces death, hearing loss, and neurological sequelae in bacterial meningitis Full Text available with Trip Pro

Review: adjuvant corticosteroid therapy reduces death, hearing loss, and neurological sequelae in bacterial meningitis Review: adjuvant corticosteroid therapy reduces death, hearing loss, and neurological sequelae in bacterial meningitis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: adjuvant corticosteroid therapy reduces death, hearing loss, and neurological sequelae in bacterial meningitis Article Text Therapeutics Review

2005 Evidence-Based Medicine

402. Review: long acting ß2-agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease Full Text available with Trip Pro

Review: long acting ß2-agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease Review: long acting β2-agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using (...) your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: long acting β2-agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease Article Text

2005 Evidence-Based Medicine

403. Review: inhaled corticosteroids slow the progression of airflow limitation in COPD Full Text available with Trip Pro

Review: inhaled corticosteroids slow the progression of airflow limitation in COPD Review: inhaled corticosteroids slow the progression of airflow limitation in COPD | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional (...) accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: inhaled corticosteroids slow the progression of airflow limitation in COPD Article Text Therapeutics Review: inhaled corticosteroids slow the progression of airflow limitation in COPD Free Michael Greenstone , MD, FRCP

2005 Evidence-Based Medicine

404. Use of inhaled corticosteroids during pregnancy and risk of pregnancy induced hypertension: nested case-control study. Full Text available with Trip Pro

Use of inhaled corticosteroids during pregnancy and risk of pregnancy induced hypertension: nested case-control study. To determine whether the use of inhaled corticosteroids during pregnancy increases the risk of pregnancy induced hypertension and pre-eclampsia among asthmatic women.Nested case-control study.Three administrative health databases from Quebec: RAMQ, MED-ECHO, and Fichier des evenements demographiques.3505 women with asthma, totalling 4593 pregnancies, between 1990 and 2000 (...) .Pregnancy induced hypertension and pre-eclampsia.302 cases of pregnancy induced hypertension and 165 cases of pre-eclampsia were identified. Use of inhaled corticosteroids from conception until date of outcome was not associated with an increased risk of pregnancy induced hypertension (adjusted odds ratio 1.02, 95% confidence interval 0.77 to 1.34) or pre-eclampsia (1.06, 0.74 to 1.53). No significant dose-response relation was observed between inhaled corticosteroids and pregnancy induced hypertension

2005 BMJ

405. Corticosteroids for acute traumatic brain injury. Full Text available with Trip Pro

Corticosteroids for acute traumatic brain injury. Traumatic brain injury is a leading cause of death and disability. Corticosteroids have been widely used in treating people with traumatic brain injury.To quantify the effectiveness and safety of corticosteroids in the treatment of acute traumatic brain injury.Electronic sources: MEDLINE, EMBASE, Cochrane Library and specialised database searches. Additional hand searching and contact with trialists. Date of the most recent search October 2004 (...) .All randomised controlled trials of corticosteroid use in acute traumatic brain injury with adequate or unclear allocation concealment.Quality of allocation concealment was scored. Data on numbers of participants randomised, numbers lost to follow up, length of follow up, case fatality rates, disablement, infections and gastrointestinal bleeds were extracted independently and checked.We identified 20 trials with 12303 randomised participants. The effect of corticosteroids on the risk of death

2005 Cochrane

406. Inhaled corticosteroids were safely stepped down in chronic, stable asthma Full Text available with Trip Pro

Inhaled corticosteroids were safely stepped down in chronic, stable asthma Inhaled corticosteroids were safely stepped down in chronic, stable asthma | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username (...) * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Inhaled corticosteroids were safely stepped down in chronic, stable asthma Article Text Therapeutics Inhaled corticosteroids were safely stepped down in chronic, stable asthma Free Jay I Peters , MD Statistics from Altmetric.com Hawkins G, McMahon

2005 Evidence-Based Medicine

407. Role of combination inhaled corticosteroids and long acting beta agonists in the treatment of adult asthma

Status Subject indexing assigned by CRD MeSH Adrenal Cortex Hormones; Adrenergic beta-Agonists; Asthma /drug therapy; Costs and Cost Analysis Language Published English, French Country of organisation Canada Address for correspondence 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392; Email: jills@ccohta.ca AccessionNumber 32005000353 Date bibliographic record published 20/07/2005 Date abstract record published 20/07/2005 Health Technology Assessment (HTA (...) Role of combination inhaled corticosteroids and long acting beta agonists in the treatment of adult asthma Role of combination inhaled corticosteroids and long acting beta agonists in the treatment of adult asthma Role of combination inhaled corticosteroids and long acting beta agonists in the treatment of adult asthma Mayers I, Damant R Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality

2005 Health Technology Assessment (HTA) Database.

408. Daily versus as-needed corticosteroids for mild persistent asthma. Full Text available with Trip Pro

Daily versus as-needed corticosteroids for mild persistent asthma. Although guidelines recommend daily therapy for patients with mild persistent asthma, prescription patterns suggest that most such patients use these so-called controller therapies intermittently. In patients with mild persistent asthma, we evaluated the efficacy of intermittent short-course corticosteroid treatment guided by a symptom-based action plan alone or in addition to daily treatment with either inhaled budesonide (...) ), and the number of symptom-free days (P=0.03), but not in post-bronchodilator FEV1 (P=0.29) or in the quality of life (P=0.18). Daily zafirlukast therapy did not differ significantly from intermittent treatment in any outcome measured.It may be possible to treat mild persistent asthma with short, intermittent courses of inhaled or oral corticosteroids taken when symptoms worsen. Further studies are required to determine whether this novel approach to treatment should be recommended.Copyright 2005

2005 NEJM Controlled trial quality: predicted high

409. Effect of initial corticosteroid therapy on coronary artery aneurysm formation in Kawasaki disease: a meta-analysis of 862 children

Effect of initial corticosteroid therapy on coronary artery aneurysm formation in Kawasaki disease: a meta-analysis of 862 children Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2005 DARE.

410. Effects of inhaled corticosteroids on mortality and hospitalisation in elderly asthma and chronic obstructive pulmonary disease patients: appraising the evidence

end points in order to evaluate the overall value to the patient of ICS treatment. Bibliographic details Schmier J K, Halpern M T, Jones M L. Effects of inhaled corticosteroids on mortality and hospitalisation in elderly asthma and chronic obstructive pulmonary disease patients: appraising the evidence. Drugs and Aging 2005; 22(9): 717-729 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Administration, Inhalation; Adrenal Cortex Hormones /economics /therapeutic use; Adrenergic beta (...) Effects of inhaled corticosteroids on mortality and hospitalisation in elderly asthma and chronic obstructive pulmonary disease patients: appraising the evidence Effects of inhaled corticosteroids on mortality and hospitalisation in elderly asthma and chronic obstructive pulmonary disease patients: appraising the evidence Effects of inhaled corticosteroids on mortality and hospitalisation in elderly asthma and chronic obstructive pulmonary disease patients: appraising the evidence Schmier J K

2005 DARE.

411. Moderate dose inhaled corticosteroids plus salmeterol versus higher doses of inhaled corticosteroids in symptomatic asthma

Moderate dose inhaled corticosteroids plus salmeterol versus higher doses of inhaled corticosteroids in symptomatic asthma Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2005 DARE.

412. Practice parameter: corticosteroid treatment of Duchenne dystrophy. Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society Full Text available with Trip Pro

Practice parameter: corticosteroid treatment of Duchenne dystrophy. Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society Practice parameter: corticosteroid treatment of Duchenne dystrophy. Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society Practice parameter: corticosteroid treatment of Duchenne dystrophy. Report (...) of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society Moxley R T, Ashwal S, Pandya S, Connolly A, Florence J, Mathews K, Baumbach L, McDonald C, Sussman M, Wade C CRD summary This review assessed the effects of corticosteroids in boys with Duchenne dystrophy. It concluded that prednisone can improve muscle strength and function and pulmonary function, and that deflazacort also provides similar benefits. This conclusion

2005 DARE.

413. Hay fever and a single intramuscular injection of corticosteroid: a systematic review

Hay fever and a single intramuscular injection of corticosteroid: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2005 DARE.

414. Economic evaluation of treating chronic obstructive pulmonary disease with inhaled corticosteroids and long-acting beta 2-agonists in a health maintenance organization Full Text available with Trip Pro

: examining systematic biases that affect the relationship between inhaled corticosteroids and survival in COPD. Eur Resp J 2003;22 Suppl 43:26s-32s. Sin DD, Golmohammadi K, Jacobs P. Cost-effectiveness of inhaled corticosteroids for chronic obstructive pulmonary disease according to disease severity. Am J Med 2004;116:325-31. Indexing Status Subject indexing assigned by NLM MeSH Administration, Inhalation; Adrenal Cortex Hormones /administration & Adrenergic beta-Agonists /administration & Aged; Cohort (...) Economic evaluation of treating chronic obstructive pulmonary disease with inhaled corticosteroids and long-acting beta 2-agonists in a health maintenance organization Economic evaluation of treating chronic obstructive pulmonary disease with inhaled corticosteroids and long-acting beta 2-agonists in a health maintenance organization Economic evaluation of treating chronic obstructive pulmonary disease with inhaled corticosteroids and long-acting beta 2-agonists in a health maintenance

2005 NHS Economic Evaluation Database.

415. A cost consequences analysis of local corticosteroid injection and physiotherapy for the treatment of new episodes of unilateral shoulder pain in primary care

A cost consequences analysis of local corticosteroid injection and physiotherapy for the treatment of new episodes of unilateral shoulder pain in primary care Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2005 NHS Economic Evaluation Database.

416. Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial. (Abstract)

Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial. Corticosteroids have been used to treat head injuries for more than 30 years. In 1997, findings of a systematic review suggested that these drugs reduce risk of death by 1-2%. The CRASH trial--a multicentre international collaboration--aimed to confirm or refute such an effect by recruiting 20000 patients. In May, 2004 (...) , the data monitoring committee disclosed the unmasked results to the steering committee, which stopped recruitment.10008 adults with head injury and a Glasgow coma score (GCS) of 14 or less within 8 h of injury were randomly allocated 48 h infusion of corticosteroids (methylprednisolone) or placebo. Primary outcomes were death within 2 weeks of injury and death or disability at 6 months. Prespecified subgroup analyses were based on injury severity (GCS) at randomisation and on time from injury

2004 Lancet Controlled trial quality: predicted high

417. Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase. (Abstract)

Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase. By contrast with patients with asthma, those with chronic obstructive pulmonary disease (COPD) are poorly responsive to the anti-inflammatory actions of corticosteroids, and these drugs provide little clinical benefit. In both diseases, multiple inflammatory genes are activated, which results from acetylation of core histones around which DNA is wound. This acetylation opens up the chromatin (...) structure allowing gene transcription and synthesis of inflammatory proteins to proceed. Corticosteroids recruit histone deacetylase 2 (HDAC2) to the actively transcribing gene, which reverses this process and switches off inflammatory gene transcription. We propose that in patients with COPD, HDAC2 function is impaired by cigarette smoking and oxidative stress, leading to a pronounced reduction in responsiveness to corticosteroids. Oxidative stress could generate peroxynitrite, which impairs HDAC2

2004 Lancet

418. Corticosteroids for treating severe sepsis and septic shock. (Abstract)

Corticosteroids for treating severe sepsis and septic shock. Sepsis may be complicated by impaired corticosteroid production. Giving corticosteroids could potentially benefit patients.To examine the effects of corticosteroids on death at one month in patients with severe sepsis and septic shock.We searched the Cochrane Infectious Diseases Group's trial register (August 2003), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library Issue 3, 2003), MEDLINE (August 2003 (...) ), EMBASE (August 2003), LILACS (August 2003), reference lists of articles, and also contacted trial authors.Randomized and quasi-randomized controlled trials of corticosteroids versus placebo or supportive treatment in severe sepsis and septic shock.Two pairs of reviewers agreed the eligibility of trials. One reviewer extracted data, which was checked by the other reviewers and the primary author of the paper whenever possible. We obtained some missing data from the trial authors. We assessed trial

2004 Cochrane

419. Corticosteroids for HELLP syndrome in pregnancy. (Abstract)

Corticosteroids for HELLP syndrome in pregnancy. Hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a severe form of pre-eclampsia. Pre-eclampsia is a multi-system disease of pregnancy associated with an increase in blood pressure and increased perinatal and maternal morbidity and mortality. Eighty per cent of women with HELLP syndrome present before term. There are suggestions from observational studies that steroid treatment in HELLP syndrome may improve disordered (...) maternal hematological and biochemical features and perhaps perinatal mortality and morbidity.To summarise the evidence on the effects of corticosteroids on maternal and neonatal mortality and morbidity in women with HELLP syndrome.We searched the Cochrane Pregnancy and Childbirth Group trials register (October 2003). We scanned lists of references from review articles and primary studies.Randomised and quasi-randomised trials evaluating the effects of adjunctive corticosteroids in patients diagnosed

2004 Cochrane

420. Azathioprine as an oral corticosteroid sparing agent for asthma. (Abstract)

Azathioprine as an oral corticosteroid sparing agent for asthma. For the majority of chronic asthmatics, symptoms are best controlled by using inhaled steroids. However, for a small group of asthmatics, symptoms can only be controlled by high doses of oral steroids. Continuous use of oral steroid is associated with severe side-effects, but it has been suggested that azathioprine, an immunosuppressive anti-metabolite, often used to reduce the immune response in chronic active hepatitis (...) and severe rheumatoid arthritis, could be useful as an oral steroid sparing agent. There is a need to systematically evaluate the evidence regarding its use to reduce or eliminate oral corticosteroid usage.The objective of this review is to assess the efficacy of adding azathioprine in patients with stable asthma who are dependent on oral corticosteroids with the intention of eventually minimizing or eliminating the use of these steroids.Searches of the Cochrane Airways Group asthma and wheeze trials

2004 Cochrane