Latest & greatest articles for corticosteroids

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Top results for corticosteroids

441. A systematic review of the adjunctive use of systemic corticosteroids for pulmonary tuberculosis

A systematic review of the adjunctive use of systemic corticosteroids for pulmonary tuberculosis A systematic review of the adjunctive use of systemic corticosteroids for pulmonary tuberculosis A systematic review of the adjunctive use of systemic corticosteroids for pulmonary tuberculosis Smego R A, Ahmed N CRD summary This review assessed adjunctive systemic corticosteroids in the treatment of pulmonary tuberculosis (PTB). The authors concluded that adjunctive systemic corticosteroids can (...) safely provide significant clinical and radiologic benefits for selected patients with advanced PTB. Since most of the included studies were conducted over 20 years ago, the relevance of the results to current practice is unknown. Authors' objectives To assess the safety and benefits of adjunctive systemic corticosteroids in the treatment of pulmonary tuberculosis (PTB). Searching MEDLINE, Index Medicus and Current Contents were searched to 2001 for studies published in English; the keywords were

2003 DARE.

442. Airway-stabilizing effect of long-acting beta2-agonists as add-on therapy to inhaled corticosteroids

University of Dundee. Bibliographic details Currie G P, Jackson C M, Ogston S A, Lipworth B J. Airway-stabilizing effect of long-acting beta2-agonists as add-on therapy to inhaled corticosteroids. QJM: an International Journal of Medicine 2003; 96(6): 435-440 Indexing Status Subject indexing assigned by NLM MeSH Adrenal Cortex Hormones /therapeutic use; Adrenergic beta-Agonists /therapeutic use; Albuterol /analogs & Asthma /prevention & Bronchodilator Agents /therapeutic use; Ethanolamines /therapeutic (...) Airway-stabilizing effect of long-acting beta2-agonists as add-on therapy to inhaled corticosteroids Airway-stabilizing effect of long-acting beta2-agonists as add-on therapy to inhaled corticosteroids Airway-stabilizing effect of long-acting beta2-agonists as add-on therapy to inhaled corticosteroids Currie G P, Jackson C M, Ogston S A, Lipworth B J CRD summary This review assessed the bronchoprotective effects of salmeterol or formeterol in patients with asthma who were using corticosteroid

2003 DARE.

443. Effects of a single course of corticosteroids given more than 7 days before birth: a systematic review

Effects of a single course of corticosteroids given more than 7 days before birth: a systematic review Effects of a single course of corticosteroids given more than 7 days before birth: a systematic review Effects of a single course of corticosteroids given more than 7 days before birth: a systematic review McLaughlin K J, Crowther C A, Walker N, Harding J E CRD summary This review concluded that exposure to a single course of prenatal corticosteroids administered more than 7 days before birth (...) does not reduce the incidence of respiratory distress syndrome, but can increase the risk of perinatal mortality, earlier birth and maternal infectious morbidity. The review was generally well-conducted and, despite a few methodological considerations, the conclusions are likely to be reliable. Authors' objectives To determine the effects of a single course of prenatal corticosteroids administered more than 7 days before birth on foetal, neonatal and maternal mortality and morbidity. Searching

2003 DARE.

444. Dose response of inhaled corticosteroids on bronchial hyperresponsiveness: a meta-analysis

Dose response of inhaled corticosteroids on bronchial hyperresponsiveness: a meta-analysis Dose response of inhaled corticosteroids on bronchial hyperresponsiveness: a meta-analysis Dose response of inhaled corticosteroids on bronchial hyperresponsiveness: a meta-analysis Currie G P, Fowler S J, Lipworth B J CRD summary This review assessed the relationship between inhaled corticosteroid dose and bronchial hyperresponsiveness in patients with asthma. The authors concluded that high doses (...) conferred greater improvements than low doses. The conclusions appear to follow from the evidence presented but it is difficult to comment on their reliability because of methodological and reporting limitations in the review. Authors' objectives To determine whether a dose-response effect exists between inhaled corticosteroids and bronchial hyper-responsiveness (BHR) in asthmatic patients. Searching MEDLINE, databases on BIDS, and the Cochrane Library were searched up to May 2001; the search terms were

2003 DARE.

445. Inhaled corticosteroids reduce the progression of airflow limitation in chronic obstructive pulmonary disease: a meta-analysis

by NLM MeSH Administration, Inhalation; Adrenal Cortex Hormones /administration & Dose-Response Relationship, Drug; Forced Expiratory Volume /drug effects; Humans; Pulmonary Disease, Chronic Obstructive /drug therapy /physiopathology; Treatment Outcome; dosage AccessionNumber 12003002293 Date bibliographic record published 31/05/2005 Date abstract record published 31/05/2005 Record Status This is a critical abstract of a systematic review that meets the criteria for inclusion on DARE. Each critical (...) Inhaled corticosteroids reduce the progression of airflow limitation in chronic obstructive pulmonary disease: a meta-analysis Inhaled corticosteroids reduce the progression of airflow limitation in chronic obstructive pulmonary disease: a meta-analysis Inhaled corticosteroids reduce the progression of airflow limitation in chronic obstructive pulmonary disease: a meta-analysis Sutherland E R, Allmers H, Ayas N T, Venn A J, Martin R J CRD summary This review assessed inhaled corticosteroids

2003 DARE.

446. The use of corticosteroids versus other treatments for Graves' ophthalmopathy: a quantitative evaluation

. Monitor 2003; 9(11): CR477-CR483 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Administration, Oral; Adrenal Cortex Hormones /therapeutic use; Cohort Studies; Graves Disease /drug therapy /radiotherapy; Humans; Radiotherapy; Random Allocation; Risk; Risk Factors AccessionNumber 12004009164 Date bibliographic record published 31/08/2005 Date abstract record published 31/08/2005 Record Status This is a critical abstract of a systematic review that meets the criteria for inclusion (...) The use of corticosteroids versus other treatments for Graves' ophthalmopathy: a quantitative evaluation The use of corticosteroids versus other treatments for Graves' ophthalmopathy: a quantitative evaluation The use of corticosteroids versus other treatments for Graves' ophthalmopathy: a quantitative evaluation Abalkhail S, Doi S A, Al-Shoumer K A CRD summary This review assessed the use of corticosteroids in the treatment of Graves' ophthalmopathy. The authors concluded that oral

2003 DARE.

447. Long-term effects of inhaled corticosteroids on FEV1 in patients with chronic obstructive pulmonary disease: a meta analysis

-term effects of inhaled corticosteroids on FEV1 in patients with chronic obstructive pulmonary disease: a meta analysis. Annals of Internal Medicine 2003; 138(12): 969-973 PubMedID Original Paper URL Other publications of related interest This additional published commentary may also be of interest. Inhaled corticosteroids in chronic obstructive pulmonary disease [letters]. Ann Intern Med 2003;139:864-5. Indexing Status Subject indexing assigned by NLM MeSH Administration, Inhalation; Adrenal (...) Cortex Hormones /administration & Forced Expiratory Volume /drug effects; Humans; Pulmonary Disease, Chronic Obstructive /drug therapy /physiopathology; Randomized Controlled Trials as Topic; Spirometry; dosage AccessionNumber 12003008328 Date bibliographic record published 31/01/2006 Date abstract record published 31/01/2006 Record Status This is a critical abstract of a systematic review that meets the criteria for inclusion on DARE. Each critical abstract contains a brief summary of the review

2003 DARE.

448. Treatment of atopic dermatitis and impact on quality of life: a review with emphasis on topical non-corticosteroids

in AD. Future research should therefore attempt to further assess this issue. Bibliographic details Schiffner R, Schiffner-Rohe J, Landthaler M, Stolz W. Treatment of atopic dermatitis and impact on quality of life: a review with emphasis on topical non-corticosteroids. PharmacoEconomics 2003; 21(3): 159-179 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Administration, Topical; Adrenal Cortex Hormones /administration & Adult; Balneology; Child; Dermatitis, Atopic /classification (...) Treatment of atopic dermatitis and impact on quality of life: a review with emphasis on topical non-corticosteroids Treatment of atopic dermatitis and impact on quality of life: a review with emphasis on topical non-corticosteroids Treatment of atopic dermatitis and impact on quality of life: a review with emphasis on topical non-corticosteroids Schiffner R, Schiffner-Rohe J, Landthaler M, Stolz W CRD summary This review assessed the impact on quality of life of different topically applicable

2003 DARE.

449. Cost-effectiveness analysis of tacrolimus ointment versus high-potency topical corticosteroids in adults with moderate to severe atopic dermatitis

Cost-effectiveness analysis of tacrolimus ointment versus high-potency topical corticosteroids in adults with moderate to severe atopic dermatitis Cost-effectiveness analysis of tacrolimus ointment versus high-potency topical corticosteroids in adults with moderate to severe atopic dermatitis Cost-effectiveness analysis of tacrolimus ointment versus high-potency topical corticosteroids in adults with moderate to severe atopic dermatitis Ellis C N, Drake L A, Prendergast M M, Abramovits W (...) , Boguniewicz M, Daniel C R, Lebwohl M, Paller A S, Stevens S R, Whitaker-Worth D L, Tong K B Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology High-potency topical corticosteroids (HPTCs) were compared with tacrolimus ointment

2003 NHS Economic Evaluation Database.

450. Inhaled corticosteroid effects on bone metabolism in asthma and mild chronic obstructive pulmonary disease. (Abstract)

using experimental doses of inhaled steroid in excess of the doses recommended by the British Thoracic Society SMD 0.97 (95% CI -1.61, -0.34). A statistically significant change in parathyroid hormone seen in one small short trial (n=10, 6 weeks) may have been due to the trial design and outcome measurements used.In patients with asthma or mild COPD, there is no evidence of an effect of inhaled corticosteroid at conventional doses given for two or three years on BMD or vertebral fracture. Higher (...) Inhaled corticosteroid effects on bone metabolism in asthma and mild chronic obstructive pulmonary disease. Inhaled corticosteroids form the main therapy for asthma, but there is increasing concern about the potential systematic effects of long-term inhaled corticosteroids including their effect on bone metabolism and bone loss.To determine the effect of inhaled corticosteroids use on biochemical markers of bone turnover, bone mineral density and the development of fractures.We searched

2002 Cochrane

451. Corticosteroids for Bell's palsy (idiopathic facial paralysis). (Abstract)

for randomised trials, as well as MEDLINE, EMBASE and LILACS (to December 2000). We contacted known experts in the field to identify additional published or unpublished trials.Randomised trials comparing different routes of administration and dosage schemes of corticosteroid or adrenocorticotrophic hormone therapy versus a control group where no therapy considered effective for this condition was administered, unless it was also given in a similar way to the experimental group.Two reviewers independently (...) Corticosteroids for Bell's palsy (idiopathic facial paralysis). Inflammation and oedema of the facial nerve are implicated in causing Bell's palsy. Corticosteroids have a potent anti-inflammatory action which should minimise nerve damage and thereby improve the outcome of patients suffering from this condition.The objective of this review was to assess the effect of steroid therapy in the recovery of patients with Bell's palsy.We searched the Cochrane Neuromuscular Disease Group register

2002 Cochrane

452. Dapsone as an oral corticosteroid sparing agent for asthma. (Abstract)

Dapsone as an oral corticosteroid sparing agent for asthma. Oral corticosteroids are used as a treatment for asthma, however they are often associated with serious side effects. Dapsone is a sulfone with anti-inflammatory properties, therefore it may have a beneficial effect in the treatment of asthma and act as a corticosteroid-sparing agent.The objective of this review is to assess the safety and efficacy of adding dapsone to oral corticosteroids in adults with stable asthma who are dependent (...) on oral corticosteroids with the intention of eventually minimizing or eliminating the use of these steroids.The Cochrane Airways group trials register and reference lists of potential articles were searched.Randomised controlled trials investigating the addition of dapsone compared to placebo in stable corticosteroid dependent asthmatics.No trials were found that met the selection criteria.No meta-analyses could be performed.No randomised controlled trials have been published, so there is no reliable

2002 Cochrane

453. A comparison of oral and topical corticosteroids in patients with bullous pemphigoid. (Abstract)

A comparison of oral and topical corticosteroids in patients with bullous pemphigoid. Bullous pemphigoid is the most common autoimmune blistering skin disease of the elderly. Because elderly people have low tolerance for standard regimens of oral corticosteroids, we studied whether highly potent topical corticosteroids could decrease mortality while controlling disease.A total of 341 patients with bullous pemphigoid were enrolled in a randomized, multicenter trial and stratified according (...) to the severity of their disease (moderate or extensive). Patients were randomly assigned to receive either topical clobetasol propionate cream (40 g per day) or oral prednisone (0.5 mg per kilogram of body weight per day for those with moderate disease and 1 mg per kilogram per day for those with extensive disease). The primary end point was overall survival.Among the 188 patients with extensive bullous pemphigoid, topical corticosteroids were superior to oral prednisone (P=0.02). The one-year survival rate

2002 NEJM Controlled trial quality: uncertain

454. Corticosteroid injections, physiotherapy, or a wait-and-see policy for lateral epicondylitis: a randomised controlled trial. Full Text available with Trip Pro

Corticosteroid injections, physiotherapy, or a wait-and-see policy for lateral epicondylitis: a randomised controlled trial. Lateral epicondylitis is generally treated with corticosteroid injections or physiotherapy. Dutch clinical guidelines recommend a wait-and-see policy. We compared the efficacy of these approaches.Patients with lateral epicondylitis of at least 6 weeks' duration were recruited by family doctors. We randomly allocated eligible patients to 6 weeks of treatment (...) with corticosteroid injections, physiotherapy, or a wait-and-see policy. Outcome measures included general improvement, severity of the main complaint, pain, elbow disability, and patient satisfaction. Severity of elbow complaints, grip strength, and pressure pain threshold were assessed by a research physiotherapist who was unaware of treatment allocation. We assessed all outcomes at 3, 6, 12, 26, and 52 weeks. The principal analysis was done on an intention-to-treat basis.We randomly assigned 185 patients. At 6

2002 Lancet Controlled trial quality: predicted high

455. Randomised controlled trial of short bursts of a potent topical corticosteroid versus prolonged use of a mild preparation for children with mild or moderate atopic eczema. Full Text available with Trip Pro

Randomised controlled trial of short bursts of a potent topical corticosteroid versus prolonged use of a mild preparation for children with mild or moderate atopic eczema. To determine whether a three day burst of a potent corticosteroid is more effective than a mild preparation used for seven days in children with mild or moderate atopic eczema.Randomised, double blind, parallel group study of 18 weeks' duration.13 general practices and a teaching hospital in the Nottingham area.174 children (...) improvements in disease severity and quality of life compared with baseline.A short burst of a potent topical corticosteroid is just as effective as prolonged use of a milder preparation for controlling mild or moderate atopic eczema in children.

2002 BMJ Controlled trial quality: predicted high

456. Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis

Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis Yanez A, Rodrigo G J Authors' objectives To compare (...) the effectiveness of intranasal corticosteroids with topical antihistamines for the treatment of allergic rhinitis. Searching MEDLINE (from 1966 to 2001), EMBASE (from 1980 to 2001), CINAHL (from 1982 to 2001) and the Cochrane Library (Cochrane Database of Systematic Reviews, DARE and the Cochrane Controlled Trials Register) were searched for studies in the English language; the search terms were given. Additional studies were identified by searching the bibliographies of retrieved articles and through contact

2002 DARE.

457. A meta-analysis of the dose-response relationship of inhaled corticosteroids in adolescents and adults with mild to moderate persistent asthma

with mild to moderate persistent asthma. Clinical Therapeutics 2002; 24(1): 1-20 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Administration, Inhalation; Adolescent; Adrenal Cortex Hormones /administration & Adult; Algorithms; Anti-Asthmatic Agents /administration & Asthma /drug therapy /pathology /physiopathology; Dose-Response Relationship, Drug; Humans; Randomized Controlled Trials as Topic; Respiratory Function Tests; Treatment Outcome; dosage /therapeutic use; dosage /therapeutic (...) A meta-analysis of the dose-response relationship of inhaled corticosteroids in adolescents and adults with mild to moderate persistent asthma A meta-analysis of the dose-response relationship of inhaled corticosteroids in adolescents and adults with mild to moderate persistent asthma A meta-analysis of the dose-response relationship of inhaled corticosteroids in adolescents and adults with mild to moderate persistent asthma Bousquet J, Ben-Joseph R, Messonnier M, Alemao E, Gould A L Authors

2002 DARE.

458. Corticosteroid therapy for patients with acute exacerbations of chronic obstructive pulmonary disease: a systematic review

Status Subject indexing assigned by NLM MeSH Acute Disease; Administration, Oral; Adrenal Cortex Hormones /administration & Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hydrocortisone /administration & Male; Methylprednisolone /administration & Middle Aged; Prednisolone /administration & Prednisone /administration & Prognosis; Pulmonary Disease, Chronic Obstructive /diagnosis /drug therapy /mortality; Randomized Controlled Trials as Topic; Recurrence; Severity (...) Corticosteroid therapy for patients with acute exacerbations of chronic obstructive pulmonary disease: a systematic review Corticosteroid therapy for patients with acute exacerbations of chronic obstructive pulmonary disease: a systematic review Corticosteroid therapy for patients with acute exacerbations of chronic obstructive pulmonary disease: a systematic review Singh J M, Palda V A, Stanbrook M B, Chapman K R Authors' objectives To determine whether corticosteroids are of demonstrable

2002 DARE.

459. Corticosteroids for herpes zoster: what do they accomplish?

Indexing Status Subject indexing assigned by NLM MeSH Administration, Oral; Administration, Topical; Adrenal Cortex Hormones /adverse effects /therapeutic use; Clinical Trials as Topic; Drug Administration Schedule; Herpes Zoster /complications /drug therapy; Humans; Injections /methods; Neuralgia /prevention & Pain /drug therapy /etiology; Treatment Outcome; control AccessionNumber 12002004474 Date bibliographic record published 31/07/2004 Date abstract record published 31/07/2004 Record Status (...) Corticosteroids for herpes zoster: what do they accomplish? Corticosteroids for herpes zoster: what do they accomplish? Corticosteroids for herpes zoster: what do they accomplish? Santee J A Authors' objectives To examine the effectiveness and safety of corticosteroids in the treatment of herpes zoster. Searching MEDLINE was searched from 1966 to March 2001 for articles published in the English language; the search terms were stated. The reference lists in identified studies were checked

2002 DARE.

460. The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review of randomized placebo-controlled trials

F A. The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review of randomized placebo-controlled trials. American Journal of Medicine 2002; 113(1): 59-65 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Administration, Inhalation; Adrenal Cortex Hormones /administration & Adult; Aged; Humans; Middle Aged; Multicenter Studies as Topic; Pulmonary Disease, Chronic Obstructive /drug therapy; Randomized Controlled Trials as Topic; Treatment (...) The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review of randomized placebo-controlled trials The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review of randomized placebo-controlled trials The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review of randomized placebo-controlled trials Alsaeedi A, Sin D D, McAlister F A Authors' objectives To determine whether

2002 DARE.