Latest & greatest articles for dementia

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Top results for dementia

161. Statin withdrawal in people with dementia. Full Text available with Trip Pro

Statin withdrawal in people with dementia. There are approximately 24 million people worldwide with dementia; this is likely to increase to 81 million by 2040. Dementia is a progressive condition, and usually leads to death eight to ten years after first symptoms. End-of-life care should emphasise treatments that optimise quality of life and physicians should minimise unnecessary or non-beneficial interventions. Statins are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (...) ; they have become the cornerstone of pharmacotherapy for the management of hypercholesterolaemia but their ability to provide benefit is unclear in the last weeks or months of life. Withdrawal of statins may improve quality of life in people with advanced dementia, as they will not be subjected to unnecessary polypharmacy or side effects. However, they may help to prevent further vascular events in people of advanced age who are at high risk of such events.To evaluate the effects of withdrawal

2016 Cochrane

162. Improving care for people with dementia: development and initial feasibility study for evaluation of life story work in dementia care Full Text available with Trip Pro

Improving care for people with dementia: development and initial feasibility study for evaluation of life story work in dementia care Improving care for people with dementia: development and initial feasibility study for evaluation of life story work in dementia care Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try

2016 NIHR HTA programme

163. Calcium supplementation and risk of dementia in women with cerebrovascular disease Full Text available with Trip Pro

Calcium supplementation and risk of dementia in women with cerebrovascular disease To determine whether calcium supplementation is associated with the development of dementia in women after a 5-year follow-up.This was a longitudinal population-based study. The sample was derived from the Prospective Population Study of Women and H70 Birth Cohort Study in Gothenburg, Sweden, and included 700 dementia-free women aged 70-92 years. At baseline in 2000-2001, and at follow-up in 2005-2006, the women (...) underwent comprehensive neuropsychiatric and somatic examinations. A CT scan was performed in 447 participants at baseline. Information on the use and dosage of calcium supplements was collected. Dementia was diagnosed according to DSM-III-R criteria.Women treated with calcium supplements (n = 98) were at a higher risk of developing dementia (odds ratio [OR] 2.10, 95% confidence interval [CI] 1.01-4.37, p = 0.046) and the subtype stroke-related dementia (vascular dementia and mixed dementia) (OR 4.40

2016 EvidenceUpdates

164. Prestroke Vascular Pathology and the Risk of Recurrent Stroke and Poststroke Dementia Full Text available with Trip Pro

Prestroke Vascular Pathology and the Risk of Recurrent Stroke and Poststroke Dementia Improved short-term survival after stroke has necessitated quantifying risk and risk factors of long-term sequelae after stroke (ie, recurrent stroke and dementia). This risk may be influenced by exposure to cardiovascular risk factors before the initial stroke. Within the population-based Rotterdam Study, we determined the long-term risk of recurrent stroke and dementia, and the proportion of recurrent (...) strokes and poststroke dementia cases that are attributable to prestroke cardiovascular risk factors (ie, the population attributable risk).We followed up 1237 patients with first-ever stroke and 4928 stroke-free participants, matched on age, sex, examination round, and stroke date (index date), for the occurrence of stroke or dementia. We calculated incidence rates in both groups and estimated the individual and combined population attributable risk of prestroke cardiovascular risk factors for both

2016 EvidenceUpdates

165. The Prevalence of Visual Impairment in People with Dementia (the PrOVIDe study): a cross-sectional study of people aged 60-89 years with dementia and qualitative exploration of individual, carer and professional perspectives

The Prevalence of Visual Impairment in People with Dementia (the PrOVIDe study): a cross-sectional study of people aged 60-89 years with dementia and qualitative exploration of individual, carer and professional perspectives The Prevalence of Visual Impairment in People with Dementia (the PrOVIDe study): a cross-sectional study of people aged 60-89 years with dementia and qualitative exploration of individual, carer and professional perspectives The Prevalence of Visual Impairment in People (...) with Dementia (the PrOVIDe study): a cross-sectional study of people aged 60-89 years with dementia and qualitative exploration of individual, carer and professional perspectives Bowen M, Edgar DF, Hancock B, Haque S, Shah R, Buchanan S, Iliffe S, Maskell S, Pickett J, Taylor J-P, O'leary N Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Bowen M

2016 Health Technology Assessment (HTA) Database.

166. Improving care for people with dementia: development and initial feasibility study for evaluation of life story work in dementia care

Improving care for people with dementia: development and initial feasibility study for evaluation of life story work in dementia care Improving care for people with dementia: development and initial feasibility study for evaluation of life story work in dementia care Improving care for people with dementia: development and initial feasibility study for evaluation of life story work in dementia care Gridley K, Brooks J, Birks Y, Baxter K, Parker G. Record Status This is a bibliographic record (...) of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Gridley K, Brooks J, Birks Y, Baxter K, Parker G.. Improving care for people with dementia: development and initial feasibility study for evaluation of life story work in dementia care. Health Services and Delivery Research 2016; 4(23) Authors' objectives To establish whether or not full evaluation of Life story work (LSW) was feasible. Improving

2016 Health Technology Assessment (HTA) Database.

167. Tube-Feeding in US Nursing Home Residents with Advanced Dementia, 2000–2014 Full Text available with Trip Pro

Tube-Feeding in US Nursing Home Residents with Advanced Dementia, 2000–2014 27533163 2016 09 13 2018 12 02 1538-3598 316 7 2016 Aug 16 JAMA JAMA Tube Feeding in US Nursing Home Residents With Advanced Dementia, 2000-2014. 769-70 10.1001/jama.2016.9374 Mitchell Susan L SL Hebrew SeniorLife Institute for Aging Research, Harvard Medical School, Boston, Massachusetts. Mor Vincent V Center for Gerontology and Health Care Research, Brown University, Providence, Rhode Island. Gozalo Pedro L PL (...) , N.I.H., Extramural United States JAMA 7501160 0098-7484 AIM IM African Continental Ancestry Group statistics & numerical data Aged, 80 and over Dementia ethnology Enteral Nutrition statistics & numerical data trends Female Humans Male Nursing Homes statistics & numerical data Poisson Distribution Regression Analysis Time Factors United States 2016 8 18 6 0 2016 8 18 6 0 2016 9 14 6 0 ppublish 27533163 2544627 10.1001/jama.2016.9374 PMC4991625 NIHMS797122 J Am Geriatr Soc. 2012 Oct;60(10):1918-21

2016 JAMA

168. Training programmes for family caregivers of people with dementia living at home: integrative review (Abstract)

Training programmes for family caregivers of people with dementia living at home: integrative review To establish primary features of training programmes designed to assist family caregivers of people with dementia living at home and to propose a model programme based on literature findings.Due to dementia's distinctive progression, there is a widely felt need to train family members who undertake the responsibility of caring for relatives diagnosed with this condition to provide positive care (...) , particularly during the early and middle stages of the disease.Integrative review.Literature reviews were carried out in the Pubmed, CINAHL, Mediclatina and Medline databases, using the following describers: training programme, family caregivers, dementia and aged. Such searches encompassed publications between 2004-2014, together with eight articles for review due to their positive identification with the inclusion criteria. Relevant results were extracted, the subsequent analysis performed

2016 EvidenceUpdates

169. Predicting 2-Year Risk of Developing Pneumonia in Older Adults without Dementia Full Text available with Trip Pro

Predicting 2-Year Risk of Developing Pneumonia in Older Adults without Dementia To develop three prognostic indices of varying degree of required detail for 2-year pneumonia risk in older adults.Retrospective cohort study.Group Health (GH), an integrated healthcare delivery system.Community-dwelling dementia-free individuals aged 65 and older who had been GH members for at least 2 years before start of follow-up and were enrolled in the Adult Changes in Thought study (N = 3,375; development

2016 EvidenceUpdates

170. The Prevalence of Visual Impairment in People with Dementia (the PrOVIDe study): a cross-sectional study of people aged 60-89 years with dementia and qualitative exploration of individual, carer and professional perspectives Full Text available with Trip Pro

The Prevalence of Visual Impairment in People with Dementia (the PrOVIDe study): a cross-sectional study of people aged 60-89 years with dementia and qualitative exploration of individual, carer and professional perspectives The Prevalence of Visual Impairment in People with Dementia (the PrOVIDe study): a cross sectional study of 60-89 year old people with dementia and qualitative exploration of individual, carer and professional perspectives Journals Library An error occurred retrieving

2016 NIHR HTA programme

171. Effectiveness of a 6-year multidomain vascular care intervention to prevent dementia (preDIVA): a cluster-randomised controlled trial. Full Text available with Trip Pro

Effectiveness of a 6-year multidomain vascular care intervention to prevent dementia (preDIVA): a cluster-randomised controlled trial. Cardiovascular risk factors are associated with an increased risk of dementia. We assessed whether a multidomain intervention targeting these factors can prevent dementia in a population of community-dwelling older people.In this open-label, cluster-randomised controlled trial, we recruited individuals aged 70-78 years through participating general practices (...) in the Netherlands. General practices within each health-care centre were randomly assigned (1:1), via a computer-generated randomisation sequence, to either a 6-year nurse-led, multidomain cardiovascular intervention or control (usual care). The primary outcomes were cumulative incidence of dementia and disability score (Academic Medical Center Linear Disability Score [ALDS]) at 6 years of follow-up. The main secondary outcomes were incident cardiovascular disease and mortality. Outcome assessors were masked

2016 Lancet Controlled trial quality: predicted high

172. Incidence of Dementia over Three Decades in the Framingham Heart Study. Full Text available with Trip Pro

Incidence of Dementia over Three Decades in the Framingham Heart Study. 27406362 2016 07 14 2019 02 16 1533-4406 375 1 2016 07 07 The New England journal of medicine N. Engl. J. Med. Incidence of Dementia over Three Decades in the Framingham Heart Study. 93-4 10.1056/NEJMc1604823 Satizabal Claudia C Beiser Alexa S AS Seshadri Sudha S eng R01 NS017950 NS NINDS NIH HHS United States R01 AG049607 AG NIA NIH HHS United States R01 AG008122 AG NIA NIH HHS United States R01 AG033193 AG NIA NIH HHS (...) United States R01 AG033040 AG NIA NIH HHS United States U01 AG049505 AG NIA NIH HHS United States Letter Comment United States N Engl J Med 0255562 0028-4793 AIM IM N Engl J Med. 2016 Feb 11;374(6):523-32 26863354 N Engl J Med. 2016 Jul 7;375(1):92-3 27406363 N Engl J Med. 2016 Jul 7;375(1):93 27406364 Dementia epidemiology Female Humans Male 2016 7 14 6 0 2016 7 15 6 0 2016 7 15 6 1 ppublish 27406362 10.1056/NEJMc1604823 10.1056/NEJMc1604823#SA3 PMC6374770 NIHMS1005329

2016 NEJM

173. Incidence of Dementia over Three Decades in the Framingham Heart Study. Full Text available with Trip Pro

Incidence of Dementia over Three Decades in the Framingham Heart Study. 27406363 2016 07 14 2018 12 02 1533-4406 375 1 2016 07 07 The New England journal of medicine N. Engl. J. Med. Incidence of Dementia over Three Decades in the Framingham Heart Study. 92-3 10.1056/NEJMc1604823 Binder Nadine N University of Freiburg Medical Center, Freiburg, Germany nadine.binder@imbi.uni-freiburg.de. Schumacher Martin M University of Freiburg Medical Center, Freiburg, Germany nadine.binder@imbi.uni (...) -freiburg.de. eng Letter Comment United States N Engl J Med 0255562 0028-4793 AIM IM N Engl J Med. 2016 Feb 11;374(6):523-32 26863354 N Engl J Med. 2016 Jul 7;375(1):93-4 27406362 Dementia epidemiology Female Humans Male 2016 7 14 6 0 2016 7 15 6 0 2016 7 15 6 1 ppublish 27406363 10.1056/NEJMc1604823 10.1056/NEJMc1604823#SA1

2016 NEJM

174. Incidence of Dementia over Three Decades in the Framingham Heart Study. Full Text available with Trip Pro

Incidence of Dementia over Three Decades in the Framingham Heart Study. 27406364 2016 07 14 2018 12 02 1533-4406 375 1 2016 07 07 The New England journal of medicine N. Engl. J. Med. Incidence of Dementia over Three Decades in the Framingham Heart Study. 93 10.1056/NEJMc1604823 Hinterberger Margareta M Medical Research Society, Vienna, Austria margareta.hinterberger@utanet.at. Fischer Peter P Medical Research Society, Vienna, Austria margareta.hinterberger@utanet.at. Zehetmayer Sonja S Medical (...) University of Vienna, Vienna, Austria. eng Letter Comment United States N Engl J Med 0255562 0028-4793 AIM IM N Engl J Med. 2016 Feb 11;374(6):523-32 26863354 N Engl J Med. 2016 Jul 7;375(1):93-4 27406362 Dementia epidemiology Female Humans Male 2016 7 14 6 0 2016 7 15 6 0 2016 7 15 6 1 ppublish 27406364 10.1056/NEJMc1604823 10.1056/NEJMc1604823#SA2

2016 NEJM

175. The International Dementia Alliance Instrument for Feasible and Valid Staging of Individuals with Dementia by Informal Caregivers (Abstract)

The International Dementia Alliance Instrument for Feasible and Valid Staging of Individuals with Dementia by Informal Caregivers To assess the feasibility and validity of the International Dementia Alliance (IDEAL) instrument for Informal Caregivers (IDEAL-IC), which is based on the IDEAL instrument for professionals (IDEAL-P), for staging individuals with dementia.Cross-sectional.Memory clinic of a university hospital.Informal caregivers of 73 community-dwelling elderly adults referred (...) to a memory clinic and six geriatric registrars.Caregivers completed the IDEAL-IC; physicians completed the original IDEAL-P and the Clinical Dementia Rating sum of boxes (CDR-SB). Missing items and floor and ceiling effects were reviewed to assess feasibility. To test construct validity, a priori hypotheses were defined for expected correlations between IDEAL-IC, IDEAL-P, and CDR-SB scores.Seventy-three IDEAL-IC instruments were completed, 86% of which had no missing items. Three percent of all 730

2016 EvidenceUpdates

176. Treatment for Dementia: Learning from Breakthroughs for Other Conditions Full Text available with Trip Pro

Treatment for Dementia: Learning from Breakthroughs for Other Conditions The past few decades have seen a number of medical breakthroughs that enabled the effective treatment of a range of conditions, transforming them from fatal into manageable ones. Examples include certain cancers and HIV. Conversely, progress on dementia has been limited. There are currently no treatments that will cure or even alter the progressive course of dementia, despite ongoing research investigating new therapies (...) and care options. The UK Department of Health is interested in the potential to learn from other disease areas to better understand the particular social, economic, political, legislative and scientific contexts that have contributed to accelerating progress and breakthroughs in treatment. Such learning could helpfully inform dementia research and innovation efforts, and help identify levers for supportive policy development. This project analysed breakthroughs in the treatment of four selected

2016 Rand health quarterly

177. Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia Full Text available with Trip Pro

Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia The American Heart Association developed the ideal cardiovascular health (CVH) index as a simple tool to promote CVH; yet, its association with brain atrophy and dementia remains unexamined.Our aim was to investigate the prospective association of ideal CVH with vascular brain injury, including the 10-year risks of incident stroke and dementia, as well as cognitive decline and brain atrophy on magnetic (...) resonance imaging, measured for ≈7 years. We studied 2750 stroke- and dementia-free Framingham Heart Study Offspring cohort participants (mean age, 62±9 years; 45% men). Ideal CVH was quantified on a 7-point scale with 1 point awarded for each of the following: nonsmoking status, ideal body mass index, regular physical activity, healthy diet, as well as optimum blood pressure, cholesterol, and fasting blood glucose. Both recent (baseline) and remote (6.9 years earlier) ideal CVH scores were

2016 EvidenceUpdates

178. Persistence of Antipsychotic Treatment in Elderly Dementia Patients: A Retrospective, Population-Based Cohort Study Full Text available with Trip Pro

Persistence of Antipsychotic Treatment in Elderly Dementia Patients: A Retrospective, Population-Based Cohort Study Antipsychotics are commonly used to manage behavioral and psychological symptoms of dementia. Concerns over their safety and efficacy in this role have resulted in antipsychotics typically being recommended for short-term usage only when used among dementia patients. However, there is little work examining the duration of antipsychotic treatment in the elderly dementia patient (...) population.To determine the persistence of use of antipsychotics in elderly dementia patients and the role of dose on therapy duration.A retrospective, population-based cohort study using administrative data, including dispensing records from a provincial public drug program, from Ontario, Canada between 2009 and 2012. Elderly dementia patients newly initiated onto antipsychotics were followed until drug discontinuation, death, 2-year follow-up, or end of study. Competing risk analysis was performed

2016 Drugs - real world outcomes

179. Sensory stimulation for persons with dementia: a review of the literature Full Text available with Trip Pro

Sensory stimulation for persons with dementia: a review of the literature To provide an overview of available sensory stimulation interventions, and their effect on persons with dementia and to present theoretical and methodological characteristics of the studies included.Different sensory stimulation interventions are used for persons with dementia to increase alertness, reduce agitation and improve quality of life. However, the effect of these interventions is not clear, neither

2016 EvidenceUpdates

180. Nonpharmacologic interventions for agitation and aggression in dementia

Nonpharmacologic interventions for agitation and aggression in dementia Nonpharmacologic interventions for agitation and aggression in dementia Nonpharmacologic interventions for agitation and aggression in dementia Brasure M, Jutkowitz E, Fuchs E, Nelson VA, Kane RA, Shippee T, Fink HA, Sylvanus T, Ouellette J, Butler M, Kane RL Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has (...) been made for the HTA database. Citation Brasure M, Jutkowitz E, Fuchs E, Nelson VA, Kane RA, Shippee T, Fink HA, Sylvanus T, Ouellette J, Butler M, Kane RL. Nonpharmacologic interventions for agitation and aggression in dementia. Rockville: Agency for Healthcare Research and Quality (AHRQ). Comparative Effectiveness Review No. 177. 2016 Authors' objectives To assess the efficacy, comparative effectiveness, and adverse effects of nonpharmacologic interventions for agitation and aggression

2016 Health Technology Assessment (HTA) Database.