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Latest & greatest articles for elderly
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on elderly or other clinical topics then use Trip today.
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of this study, papers, including original articles, theses, and conference proceedings on the prevalence of malnutrition among peopleaged 60 years and above, and have been published in national and international journals until September 2018 will be included without any language limitation. The following keywords along with their synonyms in Persian will be used in the literature search: malnutrition, elderly, and Iran. At first, the screening process will be conducted based on our inclusion and exclusion (...) Prevalence of Malnutrition Among ElderlyPeople in Iran: Protocol for a Systematic Review and Meta-Analysis. Malnutrition occurs following a decrease or an imbalance in the absorption of energy, protein, vitamins, and minerals because of numerous factors. Thus, it has serious and life-threatening consequences. To plan for this issue, we need information on the burden of this problem.The aim of this study is to determine the prevalence of malnutrition among elderlypeople in Iran.For the purpose
Effect of anticoagulation therapy in older patients with chronic kidney disease and atrial fibrillation: A meta-analysis. The role of anticoagulation therapy for stroke prevention in older atrial fibrillation (AF) patients with chronic kidney disease (CKD) remains unclear. Therefore, we conducted a meta-analysis to explore the efficacy and safety of anticoagulation therapy in this population.The Cochrane Library, PubMed, and Embase databases were systematically searched for studies reporting (...) the effect of anticoagulation therapy in older patients with AF and CKD. The risk ratios (RRs) and 95% confidence intervals (CIs) were regarded as the risk estimates. A random-effects model selected was to evaluate the treatment outcomes. The presentations were based on the Preferred Reporting Items for reporting systematic reviews and meta-analyses statement.A total of 7 studies with 24,794 older patients with AF and CKD were included. The follow-up of the included studies ranged from 0.9 to 9.0 years
Dental status of the Iranian elderly: A systematic review and meta-analysis. Tooth loss is an important health dilemma. The aim of the present study was to perform a systematic review and meta-analysis of dental status and edentulism in the elderly residing in Iran. An electronic search of the literature was carried out on Farsi and English databases using the following keywords: edentulism, dental caries, elderly, oral and dental health, edentulous, geriatric, caries, dentate, Iran (...) (48.7%) were completely edentulous (95% confidence interval [CI]: .49-.49). Of the 4423 participants evaluated in 12 studies, 2286 (51.7%) were dentate (95% CI: .52-.52). The mean number of remaining teeth was 5.73 (95% CI: 5.73-5.73) in six studies conducted on 2782 participants. Approximately 50% of the elderly in Iran are completely edentulous. Efforts should be made to improve dental care instruction, provision of dental care services in the public sector, and dental insurance coverage
reference standards without an explicit critical appraisal.The use of ubiquitous in-home monitoring and smart technologies for agedpeople's care will increase their independence and the health care services available to them as well as improve frail elderlypeople's health care outcomes. This review identified four different themes that require different conceptual approaches to solution development. Although the engineering teams were focused on prototype and algorithm development, the medical science (...) Innovative Assisted Living Tools, Remote Monitoring Technologies, Artificial Intelligence-Driven Solutions, and Robotic Systems for Aging Societies: Systematic Review. The increase in life expectancy and recent advancements in technology and medical science have changed the way we deliver health services to the aging societies. Evidence suggests that home telemonitoring can significantly decrease the number of readmissions, and continuous monitoring of older adults' daily activities and health
Outcomes of deprescribing interventions in older patients with life-limiting illness and limited life expectancy: A systematic review. Older patients with life-limiting illness (LLI) and limited life expectancy (LLE) continue to receive potentially inappropriate medicines, consequently deprescribing is often necessary. However, deprescribing in this population can be complex and challenging. Therefore, we aimed to investigate the evidence for outcomes of deprescribing interventions in older (...) patients with LLI and LLE.Studies on deprescribing intervention and their outcomes in age ≥65 years with LLI and LLE were searched using PubMed, EMBASE, Cumulative Index to Nursing and Allied Health Literature, PsycINFO and Google Scholar. Medication appropriateness was primary outcome, while clinical and cost-related outcomes were secondary. Eligibility, data extraction and quality assessment were followed by a narrative synthesis of data.Of 9 studies (1375 participants), 3 reported on primary outcome
Dexmedetomidine versus propofol sedation in reducing delirium among older adults in the ICU: A systematic review and meta-analysis. Delirium is common in the ICU, with incidence rates reported to be upwards of 70%. Due to the significant morbidity and mortality associated with delirium, it is hypothesised that a delirium-free sedative agent will improve outcomes in older adults admitted to the ICU.To assess if dexmedetomidine sedation is associated with a reduction in ICU delirium among older (...) as an outcome and had a mean/median sample age of at least 60. Studies that examined dexmedetomidine and propofol use intra-operatively or as part of general anaesthesia were excluded.Dexmedetomidine sedation was associated with a lower incidence of delirium when compared with propofol: seven studies, n=1249; risk ratio 0.70; 95% confidence interval (CI) 0.52 to 0.95; P = 0.02. There was no statistically significant difference in the incidence of bradycardia: three studies, n=278; risk ratio 1.52; 95% CI
The Relationship between Physical Frailty and Mild Cognitive Impairment in the Elderly: A Systematic Review. Physical frailty (PF) appears to be associated with low cognitive performance and mild cognitive impairment (MCI). This review evaluated and synthesized the evidence of studies investigating the association between PF and MCI, the prevalence of both conditions and the rate of conversion of healthy older adult to one of them during the follow-up.A systematic review was performed according
that CIT with exercise displayed greater improvements in walking speed than exercise alone.CIT supplementation seems to be able to improve muscular and physical factors in frail elderlypeople (malnourished, hypertensive, obese, dynapenic-obese) compared to placebo. More importantly, CIT combined to exercise is more efficient than exercise or CIT alone. However, because of the small number (six) and heterogeneity (dose, duration, population) of the studies realized in older adults, further studies (...) Effects of Citrulline alone or combined with exercise on muscle mass, muscle strength, and physical performance among older adults: a systematic review. To Establish the potential of Citrulline supplementation (CIT) combined or not with exercise on muscle function and physical performance via a systematic review of randomized controlled trials (RCTs) in human aged 50 years and older.Based on Preferred Reporting Items for Systematic Reviews and Meta-analysis guideline, 103 references have been
Melatonin for the prevention of postoperative delirium in older adults: a systematic review and meta-analysis. Older surgical patients are at high risk of developing postoperative delirium. Non-pharmacological strategies are recommended for delirium prevention, but no pharmacological agents have compelling evidence to decrease the incidence of delirium. The purpose of this study was to assess whether perioperative melatonin decreases the incidence of delirium in older adults undergoing surgical (...) procedures.A systematic search using PubMed/Medline, Embase, PsycINFO, CINAHL, and references of identified articles published in English between January 1990 and October 2017 was performed. Two independent reviewers screened titles and abstracts, and then extracted data following a full-text review of included articles with consensus generation and bias assessment. Studies reporting outcomes for melatonin or ramelteon use to prevent delirium in postoperative hospitalized patients (mean age ≥ 50 years
: Introduction Depression is the leading cause of mental illness amongst an ageing population and fewer than half of those who are affected receive treatment. There is an increased need for alternative ways of treating patients; the use of video consultations has been shown to be a viable option for delivering mental health care. However, none of the existing reviews have focused on satisfaction with the use of video consultations amongst olderpeople with depression and providers. Aim To conduct (...) Patients' and providers' experiences with video consultations used in the treatment of older patients with unipolar depression: A systematic review. WHAT IS KNOWN ON THE SUBJECT?: Depression is the most common cause of mental illness amongst olderpeople. As a result of the growth of the older population, it is expected that an increasing number of olderpeople will need treatment. Depression can be effectively treated-but fewer than half of those who are affected receive treatment. Barriers
MRAs in Elderly HF Patients: Individual Patient-Data Meta-Analysis of RALES, EMPAHSIS-HF, and TOPCAT. This study sought to assess the effect of MRA treatment (vs. placebo) in older patients (≥75 years of age) compared with younger patients (<75 years of age) with heart failure (HF).Mineralocorticoid receptor antagonists (MRAs) have been shown to reduce morbidity and mortality in patients with HF with reduced ejection fraction (HFrEF) and in a subset of patients with HF with preserved EF (HFpEF (...) [heterogeneity p = Cochran's Q p value of treatment effect by study interaction] was 0.52). Cardiovascular death and all-cause death were also reduced by MRAs without significant between-trial or age (younger vs. older) heterogeneity. Worsening renal function and hyperkalemia occurred more frequently in patients taking MRAs (vs. placebo). Compared to younger patients, worsening renal function (but not hyperkalemia) was found more frequently in the elderly.MRAs reduced morbidity and mortality in elderly
effects from the current HPV vaccination program.The current HPV vaccination program is predicted to be cost saving. Extending vaccination to olderages is predicted to produce small additional health benefits and result in substantially higher incremental cost-effectiveness ratios than the current recommendation.Centers for Disease Control and Prevention. (...) Effectiveness and Cost-Effectiveness of Human Papillomavirus Vaccination Through Age 45 Years in the United States. In the United States, the routine age for human papillomavirus (HPV) vaccination is 11 to 12 years, with catch-up vaccination through age 26 years for women and 21 years for men. U.S. vaccination policy on use of the 9-valent HPV vaccine in adult women and men is being reviewed.To evaluate the added population-level effectiveness and cost-effectiveness of extending the current U.S
study. (ClinicalTrials.gov: NCT01755052).94 hospitals throughout the United States.3006 persons aged 75 years or older who were hospitalized with AMI and discharged alive.Functional impairments were assessed during hospitalization via direct measurement (cognition, mobility, muscle strength) or self-report (vision, hearing). Clinical variables associated with mortality in prior risk models were ascertained by chart review. Seventy-two candidate variables were selected for inclusion, and backward (...) Predicting 6-Month Mortality for Older Adults Hospitalized With Acute Myocardial Infarction: A Cohort Study. Older adults with acute myocardial infarction (AMI) have higher prevalence of functional impairments, including deficits in cognition, strength, and sensory domains, than their younger counterparts.To develop and evaluate the prognostic utility of a risk model for 6-month post-AMI mortality in older adults that incorporates information about functional impairments.Prospective cohort
Experiences and effectiveness of canine-assisted interventions on the health and well-being of olderpeople residing in long-term care: a mixed methods systematic review protocol. To synthesize and integrate the best available evidence on the experiences and effectiveness of canine-assisted interventions (CAIs) on the health and well-being of olderpeople residing in long-term care.Canine-assisted interventions (CAIs) are commonly used as an adjunct therapy to enhance health and well-being (...) and are often implemented in long-term care facilities. The number of studies undertaken in this area has increased substantially over the last five years; therefore, an update of two previous systematic reviews is warranted.This review will consider olderpeople who reside in long-term care facilities and who receive CAIs. For the quantitative component, CAIs will be compared to usual care, alternative therapeutic interventions or no interventions, and outcomes will be grouped under the following headings
Water, sanitation and hygiene (WASH) in sub-Saharan Africa and associations with undernutrition, and governance in children under five years of age: a systematic review. Associations between different forms of malnutrition and environmental conditions, including water, sanitation and hygiene (WASH), may contribute towards persistently poor child health, growth and cognitive development. Experiencing poor nutrition in utero or during early childhood is furthermore associated with chronic (...) diseases later in life. The primary responsibility for provision of water and sanitation, as a basic service and human right, lies with the State; however, a number of stakeholders are involved. The situation is most critical in sub-Saharan Africa (SSA), where, in 2015, 311 million people lacked a safe water source, and >70% of SSA populations were living without adequate sanitation. The aim of this paper was to conduct a systematic review to investigate the state of literature concerned with WASH
Autologous stem cell transplant in older patients (ageâ€¯â‰¥â€¯65) with newly diagnosed multiple myeloma: A systematic review and meta-analysis. While autologous stem cell transplant (ASCT) is a standard of care for newly-diagnosed younger patients with multiple myeloma, its role in older patients remains controversial. We conducted a systematic review and meta-analysis of observational studies and randomized controlled trials (RCTs) assessing the efficacy and toxicity of ASCT in older patients (...) . For overall survival, pooled observational data favored ASCT (Hazard Ratio [HR] 0.44, 95% Confidence Interval [CI] 0.34-0.58, p < .0001), while the impact of the RCT data was uncertain (HR 0.94, 95% CI 0.25-3.54, p = .93). Observational data showed higher complete response rates with ASCT (odds ratio 5.06, 95% CI 2.60-9.88, p < .0001). Progression free survival benefit from the RCTs was uncertain (HR 1.05, 95% CI 0.36-3.12, p = .93). Data were insufficient to pool for toxicity.For older patients
Barriers to palliative and hospice care utilization in older adults with cancer: A systematic review. The number of older adults with cancer and the need for palliative care among this population is increasing in the United States. The objective of this systematic review was to synthesize the evidence on the barriers to palliative and hospice care utilization in older adults with cancer. A systematic literature search was conducted using PubMed, CINAHL, PsycINFO, Embase, and Cochrane Library (...) databases (from inception to 2018) in accordance to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Research articles that examined palliative or hospice care utilization in older adults with cancer were included in this review. Fineout-Overholt's Level of Evidence was used for quality appraisal. A total of 19 studies were synthesized in this review. Barriers to palliative and hospice care utilization were categorized into socio-demographic barriers, provider
Does age have an impact on acute mountain sickness? A systematic review. Acute mountain sickness (AMS) is the most common form of illness at high altitude; however, it is still unclear whether age is a protective factor or a risk factor for the development of AMS in travellers. In recent decades, the number of travellers aged 60 years or older is increasing. Thus, the care of older travellers is a longstanding issue in travel medicine. This study aims to systematically review the current state (...) of knowledge related to the effect of oldage on the risk of AMS. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used, and the following databases were consulted: PubMed/Medline, Embase, Europe PubMed Central (EuropePMC), World Health Organization Library Database (WHOLIS), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS). The search yielded a total of 532 articles, of which 25 met the inclusion criteria, corresponding to 26 reports
Dance intervention effects on physical function in healthy older adults: a systematic review and meta-analysis. Dancing is a form of physical exercise associated with health benefits in older adults. Regular dancing can prolong healthy aging, maintain or even improve physical function, and thus enhance their quality of life. The aim of this review was to evaluate the effects of dance intervention on physical function performance in healthy older adults in randomized-controlled trials (RCTs (...) ).Five electronic databases (Cochrane Library, PsycINFO, PubMed, Scopus, and Web of Science) were searched systematically until the end of June 2018 by two independent reviewers. These searches were limited to the English language and persons with average ageolder than 65. The tool from the Cochrane Collaboration was used to assess the risk of bias. A standard meta-analysis was performed using Review Manager Software version 5.3.Thirteen RCTs from a total of 1029 older participants were included
A systematic review of factors related to employment in transition-age youth with visual impairments. Individuals with visual impairments, including transition-age youth, have much lower employment rates than their peers without disabilities. We conducted a systematic review to examine the factors that predict employment in American youth with visual impairments. Research/Method: We used a three-pronged approach to identify articles via databases search, hand search, and ancestral search. We (...) employment. Conversely, demographic and disability characteristics generally were not significant predictors of employment.These results highlight the need to teach vocational skills, particularly job search skills, to youth with visual impairments and to support their completion of postsecondary education. Because most studies involved secondary analysis of older datasets, and five relied on the same dataset, additional research should be conducted using novel and current datasets in order to replicate