Latest & greatest articles for elderly

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Top results for elderly

941. Resection for hepatocellular cancer: overpassing old barriers Full Text available with Trip Pro

Resection for hepatocellular cancer: overpassing old barriers Several recent studies have shown that the selection limits commonly used for patients with hepatocellular cancer (HCC) potentially requiring a liver resection (LR) are too restrictive. The present review aims at investigating the studies showing that LR is no longer a treatment suitable only for highly selected patients, but also for patients selectively presenting one-to-more negative factors. Several specific variables have been (...) investigated, none of them showing to be an absolute contraindication for LR: age; single vs. multiple diseases; the dimension of the nodule; hyperbilirubinemia; clinically relevant portal hypertension; Child-Pugh status; macrovascular invasion. As a consequence, LR for the treatment of HCC-on-cirrhosis is a safe and effective procedure not only in "ideal cases", but also for selected patients presenting risk factors. The presence of only one of these factors does not represent an absolute contraindication

2018 Translational gastroenterology and hepatology

942. Effect of Aspirin on All-Cause Mortality in the Healthy Elderly. Full Text available with Trip Pro

Effect of Aspirin on All-Cause Mortality in the Healthy Elderly. In the primary analysis of the Aspirin in Reducing Events in the Elderly (ASPREE) trial, now published in the Journal, we report that the daily use of aspirin did not provide a benefit with regard to the primary end point of disability-free survival among older adults. A numerically higher rate of the secondary end point of death from any cause was observed with aspirin than with placebo.From 2010 through 2014, we enrolled (...) community-dwelling persons in Australia and the United States who were 70 years of age or older (or ≥65 years of age among blacks and Hispanics in the United States) and did not have cardiovascular disease, dementia, or disability. Participants were randomly assigned to receive 100 mg of enteric-coated aspirin or placebo. Deaths were classified according to the underlying cause by adjudicators who were unaware of trial-group assignments. Hazard ratios were calculated to compare mortality between

2018 NEJM Controlled trial quality: predicted high

943. Effect of Aspirin on Disability-free Survival in the Healthy Elderly. Full Text available with Trip Pro

Effect of Aspirin on Disability-free Survival in the Healthy Elderly. Information on the use of aspirin to increase healthy independent life span in older persons is limited. Whether 5 years of daily low-dose aspirin therapy would extend disability-free life in healthy seniors is unclear.From 2010 through 2014, we enrolled community-dwelling persons in Australia and the United States who were 70 years of age or older (or ≥65 years of age among blacks and Hispanics in the United States) and did (...) 1000 person-years in the placebo group), dementia, or persistent physical disability. The rate of major hemorrhage was higher in the aspirin group than in the placebo group (3.8% vs. 2.8%; hazard ratio, 1.38; 95% CI, 1.18 to 1.62; P<0.001).Aspirin use in healthy elderly persons did not prolong disability-free survival over a period of 5 years but led to a higher rate of major hemorrhage than placebo. (Funded by the National Institute on Aging and others; ASPREE ClinicalTrials.gov number

2018 NEJM Controlled trial quality: predicted high

944. Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly. Full Text available with Trip Pro

Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly. Aspirin is a well-established therapy for the secondary prevention of cardiovascular events. However, its role in the primary prevention of cardiovascular disease is unclear, especially in older persons, who have an increased risk.From 2010 through 2014, we enrolled community-dwelling men and women in Australia and the United States who were 70 years of age or older (or ≥65 years of age among blacks and Hispanics (...) and 6.2 events per 1000 person-years, respectively (hazard ratio, 1.38; 95% CI, 1.18 to 1.62; P<0.001).The use of low-dose aspirin as a primary prevention strategy in older adults resulted in a significantly higher risk of major hemorrhage and did not result in a significantly lower risk of cardiovascular disease than placebo. (Funded by the National Institute on Aging and others; ASPREE ClinicalTrials.gov number, NCT01038583 .).

2018 NEJM Controlled trial quality: predicted high

945. Prevalence of Elder Abuse and Neglect in Iran: A Systematic Review and Meta-Analysis Full Text available with Trip Pro

heightened with the realization that the elderly population will increase dramatically in the coming decades ( ). It is predicted that the proportion of the world’s population aged 60 years and older will nearly double from about 12% in 2015 to 22% in 2050 ( , ). Iran is no exception in this regard. In 2016, about 9.3% of Iran’s population was 60 years or over, and it is expected to rise to 30% by 2050 ( ). In recent years, several studies have investigated elder abuse in different cities of Iran (...) , but none has systematically summarized them. Hence, regarding the rapid growth of the aged people in this country and the importance of the elder abuse as a factor influencing older adults’ health and quality of life, this systematic review was conducted to assess the prevalence of elder abuse and its neglect in Iran. Understanding the magnitude of elder abuse is a crucial first step in the public health approach to prevent this type of violence ( ). On the other hand, awareness about the frequency

2018 Shiraz E-Medical Journal

946. Black-white mental status trajectories: What ages do differences emerge? Full Text available with Trip Pro

Black-white mental status trajectories: What ages do differences emerge? Studies of older U.S. adults have consistently found that African Americans perform worse on cognitive measures than whites, but there are inconsistencies as to whether these findings hold over time. Moreover, studies have focused on adults 51 and older, without considering younger ages; thus it is unclear the age at which these disparities surface. The present study examines black-white disparities in mental status (...) trajectories among adults as young as 25 years over a 25-year period.Data come from the Americans' Changing Lives Study (ACL) (n = 3,617). Participants, ranging from ages 25-100 years old at baseline, were followed from 1986 to 2011 over 5 waves. Mental status was assessed at each wave using a 5-item Short Portable Mental Status Questionnaire. Growth models were used to estimate the associations between age, race, baseline status, and longitudinal changes in mental status, controlling for sociodemographic

2018 SSM - population health

947. Intensification of older adults' outpatient blood pressure treatment at hospital discharge: national retrospective cohort study. Full Text available with Trip Pro

Intensification of older adults' outpatient blood pressure treatment at hospital discharge: national retrospective cohort study. To assess how often older adults admitted to hospital for common non-cardiac conditions were discharged with intensified antihypertensive treatment, and to identify markers of appropriateness for these intensifications.Retrospective cohort study.US Veterans Administration Health System.Patients aged 65 years or over with hypertension admitted to hospital with non (...) -cardiac conditions between 2011 and 2013.Intensification of antihypertensive treatment, defined as receiving a new or higher dose antihypertensive agent at discharge compared with drugs used before admission. Hierarchical logistic regression analyses were used to control for characteristics of patients and hospitals.Among 14 915 older adults (median age 76, interquartile range 69-84), 9636 (65%) had well controlled outpatient blood pressure before hospital admission. Overall, 2074 (14%) patients were

2018 BMJ

948. TEENAGE PREGNANCY- A SYSTEMATIC REVIEW OF FETAL AND MATERNAL OUTCOME WHEN COMPARED WITH NORMAL AGED PREGNANT WOMEN Full Text available with Trip Pro

TEENAGE PREGNANCY- A SYSTEMATIC REVIEW OF FETAL AND MATERNAL OUTCOME WHEN COMPARED WITH NORMAL AGED PREGNANT WOMEN Jebmh.com Original Research Article J. Evid. Based Med. Healthc., pISSN- 2349-2562, eISSN- 2349-2570/ Vol. 5/Issue 38/Sept. 17, 2018 Page 2719 TEENAGE PREGNANCY- A SYSTEMATIC REVIEW OF FETAL AND MATERNAL OUTCOME WHEN COMPARED WITH NORMAL AGED PREGNANT WOMEN Sharda 1 , Pallavi Vijay Ambade 2 , Meena Mehta 3 , Arshi Parween 4 1 Senior Resident, Department of Obstetrics (...) and Gynaecology, PMMMH, New Delhi. 2 Practitioner, Department of Obstetrics and Gynaecology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand. 3 Associate Professor, Department of Obstetrics and Gynaecology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand. 4 Senior Resident, Department of Obstetrics and Gynaecology, LHMC, New Delhi. ABSTRACT BACKGROUND Teenage pregnancy is emerging as a global public and health problems especially in developing country like ours. Maternal age has

2018 Journal of Evidence Based Medicine and Healthcare

949. Inter-rater and intra-raters’ variability in evaluating complete dentures insertion procedure in senior undergraduates’ prosthodontics clinics Full Text available with Trip Pro

Inter-rater and intra-raters’ variability in evaluating complete dentures insertion procedure in senior undergraduates’ prosthodontics clinics Direct clinical assessment is the mainstay of evaluation in dentistry education. An effective evaluation method in prosthodontics should be equally valid and consistent; however, this is not attained frequently. A limited number of studies have applied an analytic evaluation in prosthodontics.To compare the intra- and inter-raters' variability in two

2018 Electronic physician

950. The validation of the PRISMA-7 questionnaire in community-dwelling elderly people living in Antalya, Turkey Full Text available with Trip Pro

The validation of the PRISMA-7 questionnaire in community-dwelling elderly people living in Antalya, Turkey The screening of frailty in older adults is an important issue in the preventive approach in medicine. Frailty is one of the leading causes of morbidity and premature mortality in older adults.The aim of this study was to validate the PRISMA-7 questionnaire in community-dwelling elderly people living in Antalya, Turkey.This study was cross-sectional and observational in nature (...) was translated back by two translators to English. The translation was then compiled to one text and compared with the original text. After agreement on the translation, both translations were piloted in 10 elderly people. The final form has been applied in this study. Data of the ten piloted patients have not been included into the dataset. Data were analyzed by IBM-SPSS version 22, using descriptive statistics, Pearson product-moment correlation, and receiver operator characteristic (ROC) analysis

2018 Electronic physician

951. Aicardi syndrome in a 20-year-old female Full Text available with Trip Pro

in bilateral blindness. The case is notable for her age and longevity, as most patients with Aicardi Syndrome expire much younger, as well as the presence of intact nuclei under the posterior lens capsule.Aicardi Syndrome is a rare X-linked cerebro-retinal disorder typified by seizures, agenesis of the corpus callosum, and chorioretinal lacunae. Documenting alterations from and additions to this triad of symptoms is critical to better understanding both the syndrome itself, as well as the full breadth (...) Aicardi syndrome in a 20-year-old female To describe an unusual case of Aicardi Syndrome that both affirms hallmark characteristics of the condition and introduces new observations.We report the case of a 20-year-old woman with Aicardi Syndrome who presented in respiratory distress with bradycardia and died soon thereafter. She had a history of severe mental retardation, seizure disorder, advanced scoliosis and numerous contractures in addition to congenital ocular malformations resulting

2018 American journal of ophthalmology case reports

952. Statins for primary prevention of cardiovascular events and mortality in old and very old adults with and without type 2 diabetes: retrospective cohort study. Full Text available with Trip Pro

Statins for primary prevention of cardiovascular events and mortality in old and very old adults with and without type 2 diabetes: retrospective cohort study. To assess whether statin treatment is associated with a reduction in atherosclerotic cardiovascular disease (CVD) and mortality in old and very old adults with and without diabetes.Retrospective cohort study.Database of the Catalan primary care system (SIDIAP), Spain, 2006-15.46 864 people aged 75 years or more without clinically (...) , using an additive Cox proportional hazard model.The cohort included 46 864 participants (mean age 77 years; 63% women; median follow-up 5.6 years). In participants without diabetes, the hazard ratios for statin use in 75-84 year olds were 0.94 (95% confidence interval 0.86 to 1.04) for atherosclerotic CVD and 0.98 (0.91 to 1.05) for all cause mortality, and in those aged 85 and older were 0.93 (0.82 to 1.06) and 0.97 (0.90 to 1.05), respectively. In participants with diabetes, the hazard ratio

2018 BMJ

953. Association of age and colostrum discarding with breastfeeding in Ethiopia: systematic review and meta-analyses Full Text available with Trip Pro

Association of age and colostrum discarding with breastfeeding in Ethiopia: systematic review and meta-analyses Association of age and colostrum discarding with exclusive breastfeeding in Ethiopia: systematic review and meta-analyses | bioRxiv Search for this keyword New Results Association of age and colostrum discarding with exclusive breastfeeding in Ethiopia: systematic review and meta-analyses Sisay Mulugeta Alemu , Yihun Mulugeta Alemu , Tesfa Dejenie Habtewold doi: https://doi.org (...) exclusive breastfeeding for 6 months. The aim of this meta-analyses and systematic review was to investigate whether maternal/caregivers’ age, infant age (0-6 months) and discarding colostrum affects timely initiation of breastfeeding (TIBF) and exclusive breastfeeding (EBF) in Ethiopia. Methods A systematic search of PubMed, SCOPUS, EMBASE, CINHAL, Web of Science and WHO Global Health Library electronic databases was done for all English published articles from 2000 to January 2018, supplemented

2018 Cold Spring Harbor Laboratory

954. Gender differences in post-stroke aphasia rates are caused by age. A meta-analysis and database query Full Text available with Trip Pro

women. Another line of observations suggest that women are more severely affected by stroke, which could lead to a higher aphasia rate among women. An additional potential confounding variable could be age, given that women are typically older at the time of stroke. Methods & Procedures This study consists of two parts. First, a meta-analysis of the available reports of aphasia rates in the two sexes was conducted. A comprehensive literature search yielded 25 studies with sufficient information (...) Gender differences in post-stroke aphasia rates are caused by age. A meta-analysis and database query Sex differences in post-stroke aphasia rates are caused by age. A meta-analysis and database query | bioRxiv Search for this keyword New Results Sex differences in post-stroke aphasia rates are caused by age. A meta-analysis and database query Mikkel Wallentin doi: https://doi.org/10.1101/407296 Mikkel Wallentin 1 Department of Linguistics, Cognitive Science and Semiotics, Aarhus University

2018 Cold Spring Harbor Laboratory

955. THE EFFECT OF REGIONAL VERSUS GENERAL ANAESTHESIA ON POST-OPERATIVE DELIRIUM IN ELDERLY PATIENTS UNDERGOING SURGERY FOR HIP FRACTURE: A SYSTEMATIC REVIEW Full Text available with Trip Pro

THE EFFECT OF REGIONAL VERSUS GENERAL ANAESTHESIA ON POST-OPERATIVE DELIRIUM IN ELDERLY PATIENTS UNDERGOING SURGERY FOR HIP FRACTURE: A SYSTEMATIC REVIEW THE EFFECT OF REGIONAL VERSUS GENERAL ANAESTHESIA ON POST-OPERATIVE DELIRIUM IN ELDERLY PATIENTS UNDERGOING SURGERY FOR HIP FRACTURE: A SYSTEMATIC REVIEW | Morressier We use cookies to ensure that we give you the best experience on our website Got it Signup Login Home Saved research Copy DOI Download Submission THE EFFECT OF REGIONAL VERSUS (...) GENERAL ANAESTHESIA ON POST-OPERATIVE DELIRIUM IN ELDERLY PATIENTS UNDERGOING SURGERY FOR HIP FRACTURE: A SYSTEMATIC REVIEW Submitted Sep 4, 2018 and 1 other(s) 6 Views 0 Downloads 2 Saves Video PDF Abstract 0 Datasets Presented at Sep 12 - 15, 2018 Presentation Download Abstract Hip fracture surgery is associated with significant mortality and morbidity including post-operative delirium. It is unclear whether regional or general anaesthesia may reduce the incidence of postoperative delirium. The aim

2018 Morressier

956. The PATHS curriculum for promoting social and emotional well-being among children aged 7 9 years: a cluster RCT Full Text available with Trip Pro

The PATHS curriculum for promoting social and emotional well-being among children aged 7 9 years: a cluster RCT The PATHS curriculum for promoting social and emotional well-being among children aged 7 9 years: a cluster RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information

2018 NIHR HTA programme

957. Improving care for older people with long-term conditions and social care needs in Salford: the CLASSIC mixed-methods study, including RCT Full Text available with Trip Pro

Improving care for older people with long-term conditions and social care needs in Salford: the CLASSIC mixed-methods study, including RCT Improving care for older people with long-term conditions and social care needs in Salford: the CLASSIC mixed-methods study, including RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation

2018 NIHR HTA programme

958. Supporting shared decision-making for older people with multiple health and social care needs: a realist synthesis Full Text available with Trip Pro

Supporting shared decision-making for older people with multiple health and social care needs: a realist synthesis Supporting shared decision-making for older people with multiple health and social care needs: a realist synthesis Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find (...) the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} Models of shared decision-making for older people with complex health and care needs should be a series of conversations between patients, their families and different health and care professionals. {{author}} {{($index , , , , , , & . Frances Bunn 1, * , Claire Goodman 1 , Bridget Russell 1 , Patricia Wilson 2 , Jill Manthorpe 3 , Greta Rait 4 , Isabel Hodkinson 5 , Marie-Anne

2018 NIHR HTA programme

959. Stiripentol (Diacomit) - To treat seizures associated with Dravet syndrome in patients 2 years of age and older taking clobazam

Stiripentol (Diacomit) - To treat seizures associated with Dravet syndrome in patients 2 years of age and older taking clobazam Drug Approval Package: Diacomit (stiripentol) U.S. Department of Health and Human Services Search FDA Submit search Drug Approval Package: Diacomit (stiripentol) Company: Biocodex SA Application Number: 206709 & 207223 Approval Date: 08/20/2018 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. FDA Approval (...) Letter and Labeling (PDF) (PDF) FDA Application Review Files (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) Date created: September 7, 2018 Vision impaired people having problems accessing certain pages of a PDF file may call (301) 796-3634 for assistance. Note: Documents in PDF format require the . Note: If you need help accessing information in different file formats, see . Language Assistance Available: | | | | | | | | | | | | | | | FDA Popular Content Product Areas

2018 FDA - Drug Approval Package

960. Immunogenicity and safety of an F-genotype attenuated mumps vaccine in healthy 8- to 24-month-old children Full Text available with Trip Pro

Immunogenicity and safety of an F-genotype attenuated mumps vaccine in healthy 8- to 24-month-old children Mumps vaccine immunizations have reduced the incidence of this disease. With the variation of mumps circulating strain, novel vaccine strains are always important.A 2-center parallel, randomized, double-blind noninferiority trial was performed to compare an F-genotype attenuated mumps vaccine (SP strain) to the A-genotype vaccine (S-79, Jeryl-Lynn strain) in 1080 healthy children aged 8-24 (...) . Neutralizing and hemagglutination-inhibiting antibody assays with the F- or A-genotype strains showed similar trends in geometric mean titers in the high-dose SP and S79 groups. Increased cytotoxic T lymphocyte responses were observed in all groups.The F-genotype attenuated mumps vaccine is safe, offers immunogenicity against a homologous virus, and is noninferior to the A-genotype vaccine in 8- to 24-month-old children.

2018 EvidenceUpdates