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Latest & greatest articles for elderly
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on elderly or other clinical topics then use Trip today.
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Functional brain changes associated with cognitive training in healthy older adults: A preliminary ALE meta-analysis. Accumulating evidence suggests that cognitive training (CT) programs may provide healthy older adults (OAs) with cognitive benefits that are accompanied by alterations in neural activity. The current review offers the first quantitative synthesis of the available literature on the neural effects of CT in healthy aging. It was hypothesized that OAs would evidence increased
Comment to: Ventral hernia recurrence in women of childbearing age: a systematic review and meta-analysis. T. Nouh, F. S. Ali, K. J. Krause, I. Zaimi. 30671897 2019 11 20 1248-9204 2019 Jan 22 Hernia : the journal of hernias and abdominal wall surgery Hernia Comment to: Ventral hernia recurrence in women of childbearing age: a systematic review and meta-analysis. T. Nouh, F. S. Ali, K. J. Krause, I. Zaimi. 10.1007/s10029-019-01887-y Oma E E http://orcid.org/0000-0003-0273-8992 Digestive Disease
; psychiatric disorders; stroke; cranial trauma; inclusion of participants with MCI in groups with healthy elderly or those with dementia.Fifty-five studies were selected, namely: Stroop Task (N = 30), WCST (N = 14), Go/No-Go (N = 9), Flanker Task (N = 2). Results have shown in people with MCI deficits in all the EFs considered.The results of this review support the applicability of the four experimental tasks examined for the study of EFs in people with MCI. These paradigms are useful in research (...) Executive functions in the elderly with mild cognitive impairment: a systematic review on motor and cognitive inhibition, conflict control and cognitive flexibility. Mild Cognitive Impairment (MCI) is a syndrome characterised by mild cognitive decline, on one or more domains, but which does not compromise daily functions. Several studies have investigated the relationship between MCI and deficit in executive functions (EFs) but, unlike robust evidence in the mnestic domain, the nature
Systematic Review of the Effects of Cognitive and Behavioural Interventions on Fall-Related Psychological Concerns in Older Adults. This systematic review aims to evaluate the efficacy of cognitive and behavioural interventions for improving falls-related psychological concerns. A systematic search yielded 8 randomised controlled trials eligible for inclusion. All studies compared a cognitive and behavioural intervention to a control. Meta-analysis showed that cognitive and behavioural
Barriers and Motivators of Physical Activity Participation in Middle-aged and Older-adults - A Systematic Review. Identifying the difference in barriers and motivators between middle-age and older adults could contribute toward the development of age-specific health promotion interventions. The aim of this review was to synthesize the literature on barriers and motivators for physical activity in middle-aged (50-64 years) and older adults (65-70 years). The review examined qualitative (...) and quantitative studies using the theoretical domain framework as the guiding theory. The search generated 9400 results from seven databases. A total of fifty-five articles meeting the inclusion criteria. Results indicate that barriers are comparable across the two age groups with environmental factors and resources being the most commonly identified barriers. In older adults, social influences, reinforcement and assistance in managing change were the most identified motivators. Middle-aged identified goals
Methods to evaluate perspectives of safety, independence, activity, and participation in older persons using welfare technology. A systematic review. To conduct a systematic review of existing methods to evaluate the individual aspects of welfare technology from the perspectives of independence, safety, activity, and participation. Furthermore, the study aimed to describe outcomes that have been the focus of previous research to evaluate individual aspects of welfare technology in older persons (...) living in ordinary housing.A systematic literature review in PubMed, CINAHL Plus, PsycINFO, Scopus, and Web of Science. Studies selected were those that explored the use of assistive and welfare technology devices from older persons' perspectives, and which considered the concepts of independence, safety, activity and participation, and quality of life.A broad spectrum of instruments was applied in the studies. For independence, three questionnaires were used in the identified studies. For safety
A systematic review of interventions for older adults living in jails and prisons. The population of older adults in prison is the fastest growing demographic. Older inmates are more likely to have chronic medical conditions and cognitive decline, but these conditions occur earlier and may be more complex for older inmates. Specialized interventions to manage the unique health and mental health needs of older inmates are important to improve health and reduce burden on criminal justice systems (...) . The aim of this research is to conduct a systematic review of empirically-tested interventions to improve the health or mental health of older adults living in jail or prison.We conducted a systematic review of the literature to answer two research questions: (1) what interventions designed to improve the health or mental health of older adults living in jail or prison have been empirically tested? and (2) what are the effects of the interventions on inmates' physical or mental health?Twenty-four
ratio = 0.68; 95% confidence interval = 0.48-0.96). There was also a tendency that pharmacist interventions decreased risk of hospitalizations (risk ratio = 0.88; 95% CI = 0.78-1.00), although no statistical significant.The current evidence demonstrates that clinical medication reviews for olderpeople with polypharmacy reduces the risk of ED visits. Medication reviews can be considered as another area where community pharmacists can contribute to improve patient safety. (...) Impact of Medication Reviews Delivered by Community Pharmacist to Elderly Patients on Polypharmacy: A Meta-analysis of Randomized Controlled Trials. The aim of the study was to assess the impact of medication reviews delivered by community pharmacists to elderly patients on polypharmacy.A systematic literature search was performed in four bibliographic databases/search engine (PubMed, Embase, CENTRAL, and IPA) and three gray literature sources (OpenGrey, ClinicalTrials.gov, and Digital Access
Quantifying Dynamic Balance in Young, Elderly and Parkinson's Individuals: A Systematic Review. Introduction: Falling is one of the primary concerns for people with Parkinson's Disease and occurs predominately during dynamic movements, such as walking. Several methods have been proposed to quantify dynamic balance and to assess fall risk. However, no consensus has been reached concerning which method is most appropriate for examining walking balance during unperturbed and perturbed conditions (...) , particularly in Parkinson's Disease individuals. Therefore, this systematic review aimed to assess the current literature on quantifying dynamic balance in healthy young, elderly and Parkinson's individuals during unperturbed and perturbed walking. Methods: The PubMed database was searched by title and abstract for publications quantifying dynamic balance during unperturbed and mechanically perturbed walking conditions in elderly adults and PD. Inclusion criteria required publications to be published
Natural History of Geographic Atrophy in Untreated Eyes with Nonexudative Age-Related Macular Degeneration: A Systematic Review and Meta-analysis. Systematic review and meta-analysis of the natural history of geographic atrophy (GA).Several different models have been used to describe the natural history of GA in untreated eyes, and the reported progression rates vary widely across clinical trials.We searched in MEDLINE, EMBASE, Cochrane Library, Clinicaltrials.gov, and PubMed for studies (...) for the differences in participant entry time into the studies. The model that best fit data was determined by performing residual analyses, determining the dependence of growth rate on time, and the predicted age of GA onset. The risk of bias was assessed using the Newcastle-Ottawa scale.We included 25 studies with data from 2942 eyes. The RLM yielded the best goodness of fit and predictive performance of GA progression. Cumulative data for untreated eyes fit a straight line in the RLM (r2 = 0.986
of older SSA women.Studies with primary analysis of health, wellbeing and/or healthcare utilization outcomes for women over the age of 50 from SSA countries were included. Databases searched include EMBASE, Scopus and Psycinfo.About 26 studies from six SSA countries met inclusion criteria. Studies regarding NCDs predominated (n = 12), followed by healthcare utilization (n = 4), disability (n = 4), wellbeing (n = 2), depression (n = 2) and HIV (n = 2). Every study indicated significantly lower self (...) A systematic review of physical and psychological health and wellbeing of older women in Sub-Saharan Africa. Sub-Saharan Africa (SSA) has the fastest growing proportion of older adults in the world, the majority of whom are women. Global health agendas, however, continue to deprioritise older women's health issues, including the incidence of and mortality from non-communicable disease (NCDs). This is the first systematic review to address the health, wellbeing and healthcare utilization
Complement factor B gene polymorphisms and risk of age-related macular degeneration: A meta-analysis. To investigate the potential correlation between complement factor B polymorphisms and age-related macular degeneration.We retrieved relevant articles systematically by searching PubMed and Web of Science databases. The pooled odds ratios and 95% confidence intervals were calculated for five complement factor B polymorphism rs641153, rs4151667, rs1048709, rs2072633, and rs12614 using data from (...) included articles in both random effects and fixed effect models. Subgroup meta-analysis based on age-related macular degeneration type, choroidal neovascular disease (rs641153 and rs4151667), geographic atrophy (rs641153 and rs4151667), and races was also performed.In the overall comparison, we observed that the distribution of rs641153 and the risk of age-related macular degeneration were significantly correlated (p < 0.00001). Similar results were obtained in subgroup analysis based on race
Outcomes in different age groups with primary Ewing sarcoma of the spine: a systematic review of the literature. OBJECTIVEEwing sarcoma (ES) is among the most prevalent of bone sarcomas in young people. Less often, it presents as a primary lesion of the spine (5%-15% of patients with ES).METHODSA systematic literature search was performed, querying several scientific databases per PRISMA guidelines. Inclusion criteria specified all studies of patients with surgically treated ES located (...) in the spine. Patient age was categorized into three groups: 0-13 years (age group 1), 14-20 years (age group 2), and > 21 (age group 3).RESULTSEighteen studies were included, yielding 28 patients with ES of the spine. Sixty-seven percent of patients experienced a favorable outcome, with laminectomies representing the most common (46%) of surgical interventions. One-, 2-, and 5-year survival rates were 82% (n = 23), 75% (n = 21), and 57% (n = 16), respectively. Patients in age group 2 experienced
OSC18: A Systematic Review and Meta-Analysis on Weathering and Aging Effect of Maxillofacial Silicone's Physical Properties. 30532410 2019 11 20 0972-4052 18 Suppl 1 2018 Oct Journal of Indian Prosthodontic Society J Indian Prosthodont Soc OSC18: A Systematic Review and Meta-Analysis on Weathering and Aging Effect of Maxillofacial Silicone's Physical Properties. S14-S15 10.4103/0972-4052.244608 Rahman Ahmed Mushfiqur AM Maxillofacial Prosthetic Service, School of Dental Sciences, Universiti
Efficacy of light therapy on nonseasonal depression among elderly adults: a systematic review and meta-analysis. The aim of this study was to examine the effectiveness of light therapy in the treatment of geriatric depression.A systematic review and meta-analysis were carried out. Data sources for the literature search were PubMed, Cochrane Collaboration's Central Register of Controlled Clinical Trials, Cochrane Systematic Reviews, and ClinicalTrials.gov. Controlled trials of light therapy (...) on older patients with nonseasonal depression and depression rating scales were eligible. Studies were pooled using a random-effect model for comparisons with light therapy. We used effect size (ES), which expresses changes in depression severity, in each selected meta-analysis to calculate the standardized mean difference on the basis of Hedges' adjusted g; positive values indicated that the depression severity improved after light therapy. All results were presented with 95% CIs. Statistical
of death without increasing adverse events in patients aged 70 years or older. These findings support the benefit of intensive treatment targeting SBP to ≤140 mmHg in the elderly. (...) for RCTs comparing intensive and less intensive treatments or placebo and active treatments reported until May 2017 and identified 11 RCTs in which the target or on-treatment SBP in the intensive or active treatment was less than 140 mmHg. Among the RCTs, 6 RCTs with primary or subanalysis results for patients aged 70 years or older were finally chosen for the meta-analysis. We found that intensive lowering of BP did not reduce the risk ratio (RR) of composite cardiovascular outcomes (95% CI: 0.67-1.05
Effects of Eccentric-Focused Versus Conventional Training on Lower Limb Muscular Strength in OlderPeople: A Systematic Review With Meta-Analysis. Eccentric-focused training promotes greater gains in muscle strength compared to other types of training in adults. However, for olderpeople, these findings are still not well understood. A systematic review and meta-analysis were performed using manuscripts that performed eccentric-focused (ET) and conventional resistance training (CT) at least (...) four weeks and evaluated maximum muscle strength through tests of maximum repetitions in weight machine exercises (knee extension and leg press exercises). Five studies were included (n=138). Increases in muscle strength were found in both resistance training groups, without difference between them through meta-analysis. However, a large effect size has been observed only in ET. The findings suggest that resistance training protocols are similar to improve maximal strength in olderpeople, despite
Corrigendum to "Non-vitamin K antagonist oral anticoagulants in elderly patients with atrial fibrillation: A systematic review with meta-analysis and trial sequential analysis" [Arch. Gerontol. Geriatr. 81 (March-April) (2019) 209-214]. 31036372 2019 11 20 1872-6976 83 2019 Jul - Aug Archives of gerontology and geriatrics Arch Gerontol Geriatr Corrigendum to "Non-vitamin K antagonist oral anticoagulants in elderly patients with atrial fibrillation: A systematic review with meta-analysis (...) and trial sequential analysis" [Arch. Gerontol. Geriatr. 81 (March-April) (2019) 209-214]. 338 S0167-4943(19)30102-5 10.1016/j.archger.2019.04.008 Caldeira Daniel D Laboratório de Farmacologia Clínica e Terapêutica, Faculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moniz, 1649-028, Lisboa, Portugal; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moniz, 1649-028, Lisboa, Portugal; Serviço de Cardiologia, Hospital Universitário de
) signified a 3.2 higher mortality hazard (95% confidence interval 3.1 to 3.2) over three years. Mortality varied noticeably with age, with a hazard ratio of 10.6 (8.5 to 13.3) in 18-29 year olds and 1.5 (1.4 to 1.6) in those older than 90. A positive troponin result was associated with an approximately 15 percentage points higher absolute three year mortality across all age groups. The excess mortality with a positive troponin result was heavily concentrated in the first few weeks. Results were analysed (...) Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres. To determine the relation between age and troponin level and its prognostic implication.Retrospective cohort study.Five cardiovascular centres in the UK National Institute for Health Research Health Informatics Collaborative (UK-NIHR HIC).257 948 consecutive patients undergoing troponin testing for any clinical reason between 2010 and 2017.All cause mortality.257 948
A systematic review protocol of educational programs for nursing staff on management of resident-to-resident elder mistreatment in residential aged care homes. To review evidence concerning educational programs for nursing staff on management of resident-to-resident elder mistreatment with the aim of preventing and reducing this abuse in residential aged care homes.Although elder abuse has received considerable attention, very little is known regarding resident-to-resident elder mistreatment (...) in residential aged care homes and about interventions/programs to prevent and reduce this harm. Nurses play an essential role in identifying and managing aggressive interactions. However, many nurses may not recognize these behaviours as forms of abuse. Thus, it is important to ascertain if educational programs for nursing staff have been developed and implemented.Quantitative systematic review registered on PROSPERO (CRD42017080925).A systematic search of English published studies between 1980 - 2017