Latest & greatest articles for elderly

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Top results for elderly

161. Quality of life of empty-nest elderly in China: a systematic review and meta-analysis. (Abstract)

Quality of life of empty-nest elderly in China: a systematic review and meta-analysis. We performed a systematic review and meta-analysis to evaluate the quality of life (QoL) of the empty-nest elderly in China. We searched five databases up to 20 November 2018, to identify all studies on the QoL of empty-nest elderly in China. Twenty-nine were included in the final review. Compared with the control group, the physiological function, psychological function, social function and total score (...) of QoL of empty nests were lower than those of non-empty nests. In addition, meta-analysis showed that the empty nesters were lower than the non-empty nesters in General Health, Role Physical, Bodily Pain, Role Emotional and Vitality. The existing evidence showed that the QoL of the empty-nest elderly in China was to some extent lower than that of the non-empty nest elderly.

2020 Psychology, health & medicine

162. How does decisional capacity evolve with normal cognitive aging: systematic review of the literature. (Full text)

. In ambiguous decision-making situations, the alteration of the ventromedial system is associated with changes in motivation profiles. These changes can be compensated by experience. However, difficulties arise for older adults in the case of one-off decisions, which are very common in the medical or medico-social domains.Cognitive aging is associated with a slowdown in processing speed of decision-making, especially in ambiguous situations. However, decision-making processes which are based on experience (...) How does decisional capacity evolve with normal cognitive aging: systematic review of the literature. Aging is associated with increased needs related to complex decisions, particularly in medical and social issues. However, the complexity of decision-making involves many neurological functions and structures which are potentially altered by cognitive aging.A systematic review was conducted in accordance with PRISMA guidelines to examine changes in decision-making occurring in normal cognitive

2020 European Geriatric Medicine PubMed abstract

163. Medication adherence in the older adults with chronic multimorbidity: a systematic review of qualitative studies on patient's experience. (Abstract)

of qualitative studies on patients' experience.Two electronic databases were searched for qualitative studies on medication adherence in chronic diseases (hypertension, heart disease, COPD, asthma) involving people aged 65 + . The systematic review was performed according to the PRISMA statement guidelines, employing theoretical frameworks of the ABC Taxonomy of patient adherence and Three Factor model of determinants of behaviour.The initial database search identified 1234 records, of which 39 studies were (...) Medication adherence in the older adults with chronic multimorbidity: a systematic review of qualitative studies on patient's experience. Medication non-adherence represents a socially relevant challenge, particularly when interlinked to multiple chronic diseases and polypharmacy. Non-adherence rates affect treatment efficacy and increase health care costs. The aim of the study was to identify factors influencing medication adherence in the older adults through a systematic review

2020 European Geriatric Medicine

164. Corrigendum to "Effect of age of red cells for transfusion on patient outcomes: a systematic review and meta-analysis" [Transfus Med Rev 32/2 (2018) 77-88]. (Full text)

Corrigendum to "Effect of age of red cells for transfusion on patient outcomes: a systematic review and meta-analysis" [Transfus Med Rev 32/2 (2018) 77-88]. 32295729 2020 04 16 1532-9496 2020 Apr 12 Transfusion medicine reviews Transfus Med Rev Corrigendum to "Effect of age of red cells for transfusion on patient outcomes: a systematic review and meta-analysis" [Transfus Med Rev 32/2 (2018) 77-88]. S0887-7963(20)30017-1 10.1016/j.tmrv.2020.03.002 McQuilten Zoe K ZK Australian and New Zealand

2020 Transfusion medicine reviews PubMed abstract

165. Nutritional status and functionality in geriatric rehabilitation patients: a systematic review and meta-analysis. (Full text)

Nutritional status and functionality in geriatric rehabilitation patients: a systematic review and meta-analysis. Since there is only limited evidence available for geriatric rehabilitation patients, this systematic review and meta-analysis aims to characterize the nutritional status in this population and its relationship with functionality.Eight databases were searched for full-text articles reporting baseline nutritional intake and status of adults ≥ 60 years in rehabilitation settings (...) % in this population.Although geriatric rehabilitation populations and settings were heterogeneous, a relevant percentage of geriatric rehabilitation patients were affected by a reduced nutritional status. Nutritional status was associated with decreased functionality. This emphasizes the need for screening for malnutrition and targeted nutritional intervention.

2020 European Geriatric Medicine PubMed abstract

166. A systematic review of lifestyle patterns and their association with adiposity in children aged 5-12 years. (Abstract)

A systematic review of lifestyle patterns and their association with adiposity in children aged 5-12 years. Diet, physical activity, sedentary behaviour and sleep are typically examined independently with childhood adiposity; however, their combined influence remains uncertain. This review aims to systematically summarize evidence on the clustering of these behaviours through lifestyle patterns and evaluate associations with adiposity in children aged 5-12 years. Search strategies were run

2020 Obesity reviews : an official journal of the International Association for the Study of Obesity

167. Benefits of Exercise on Influenza or Pneumonia in Older Adults: A Systematic Review. (Full text)

Benefits of Exercise on Influenza or Pneumonia in Older Adults: A Systematic Review. A coronavirus pandemic has recently become one of the greatest threats the world is facing. Older adults are under a high risk of infection because of weaker immune systems. Therefore, the purpose of this review is to summarize the recent scientific evidence that outlines the effects of exercise on influenza or pneumonia in older adults. An electronic literature search was conducted using the WEB OF SCIENCE (...) , SCIENCEDIRECT and GOOGLE SCHOLAR databases using the following keywords, "Exercise," "Older adult," "Influenza," and "Pneumonia." Any randomized control trials, cross-sectional and observational studies that related to this topic were all included. Twenty studies met the eligibility criteria for this review. Thirteen randomized control trials investigated the effects of exercise on the immune responses to influenza or pneumonia vaccination: seven trials employed moderate aerobic exercise, three employed

2020 International journal of environmental research and public health PubMed abstract

168. Trace Mineral Intake and Deficiencies in Older Adults Living in the Community and Institutions: A Systematic Review. (Full text)

Trace Mineral Intake and Deficiencies in Older Adults Living in the Community and Institutions: A Systematic Review. The global population is ageing with many older adults suffering from age-related malnutrition, including micronutrient deficiencies. Adequate nutrient intake is vital to enable older adults to continue living independently and delay their institutionalisation, as well as to prevent deterioration of health status in those living in institutions. This systematic review (...) investigated the insufficiency of trace minerals in older adults living independently and in institutions. We examined 28 studies following a cross-sectional or cohort design, including 7203 older adults (≥60) living independently in 13 Western countries and 2036 living in institutions in seven Western countries. The estimated average requirement (EAR) cut-off point method was used to calculate percentage insufficiency for eight trace minerals using extracted mean and standard deviation values. Zinc

2020 Nutrients PubMed abstract

169. Interventions for increasing fruit and vegetable consumption in children aged five years and under. (Abstract)

Interventions for increasing fruit and vegetable consumption in children aged five years and under. Insufficient consumption of fruits and vegetables in childhood increases the risk of future non-communicable diseases, including cardiovascular disease. Interventions to increase consumption of fruit and vegetables, such as those focused on specific child-feeding strategies and parent nutrition education interventions in early childhood may therefore be an effective strategy in reducing (...) this disease burden.To assess the effectiveness, cost effectiveness and associated adverse events of interventions designed to increase the consumption of fruit, vegetables or both amongst children aged five years and under.We searched CENTRAL, MEDLINE, Embase and two clinical trials registries to identify eligible trials on 25 August 2019. We searched Proquest Dissertations and Theses in May 2019. We reviewed reference lists of included trials and handsearched three international nutrition journals. We

2020 The Cochrane database of systematic reviews

170. The incremental predictive value of frailty measures in elderly patients undergoing cardiac surgery: A systematic review. (Full text)

The incremental predictive value of frailty measures in elderly patients undergoing cardiac surgery: A systematic review. Emerging evidence demonstrates that frailty measures can predict adverse outcomes after cardiac procedures. Our objectives were to examine whether the inclusion of frailty measures adds incremental predictive value to existing surgical risk prediction models in patients undergoing cardiac surgery and to evaluate the reporting and methods of studies that investigated

2020 Clinical cardiology PubMed abstract

171. Relation between age and carotid artery intima-medial thickness: a systematic review. (Full text)

Relation between age and carotid artery intima-medial thickness: a systematic review. Carotid artery intima-medial thickness (cIMT) represents a popular measure of atherosclerosis and is predictive of future cardiovascular and cerebrovascular events. Although older age is associated with a higher cIMT, little is known about whether this increase in cIMT follows a linear relationship with age or it is affected under influence of cardiovascular diseases (CVD) or CVD risk factors. We hypothesize (...) that the relationship between cIMT and age is nonlinear and is affected by CVD or risk factors. A systematic review of studies that examined cIMT in the general population and human populations free from CVD/risk factors was undertaken. The literature search was conducted in PubMed, Scopus, and Web of Science. Seventeen studies with 32 unique study populations, involving 10,124 healthy individuals free from CVD risk factors, were included. Furthermore, 58 studies with 115 unique study populations were included

2020 Clinical cardiology PubMed abstract

172. The effectiveness of nurse-led interventions for preventing urinary tract infections in older adults in residential aged care facilities: A systematic review. (Abstract)

The effectiveness of nurse-led interventions for preventing urinary tract infections in older adults in residential aged care facilities: A systematic review. To explore the effectiveness of nurse-led interventions to prevent urinary tract infections in older adults living in residential aged care facilities.While most empirical studies focus on the treatment of urinary tract infections, few studies have examined the effectiveness of nurse-led interventions in preventing urinary tract (...) infections.Systematic review.Eight electronic databases were searched for relevant studies published between 2008-2018. The inclusion criteria were as follows: (a) a focus on older adults, (b) evaluation of nurse-led interventions, focusing on prevention of urinary tract infection, (c) implemented in residential aged care facilities, and (d) outcomes reported as incidence or prevalence of urinary tract infection. The selected papers were critically appraised using the Mixed Methods Appraisal Tool. The data were

2020 Journal of clinical nursing

173. Screening Tools Used by Clinical Pharmacists to Identify Elderly Patients at Risk of Drug-Related Problems on Hospital Admission: A Systematic Review. (Full text)

Screening Tools Used by Clinical Pharmacists to Identify Elderly Patients at Risk of Drug-Related Problems on Hospital Admission: A Systematic Review. None of the models met the four key stages required to create a quality risk prediction model. Further research is needed to either refine the tools developed to date or develop new ones that have good performance and have been externally validated before considering the potential impact and implementation of such tools.

2020 Pharmacy (Basel, Switzerland) PubMed abstract

174. Window of opportunity in rheumatoid arthritis - definitions and supporting evidence: from old to new perspectives. (Full text)

Window of opportunity in rheumatoid arthritis - definitions and supporting evidence: from old to new perspectives. The therapeutic window of opportunity in rheumatoid arthritis (RA) is often referred to. However, some have questioned whether such a period, in which the disease is more susceptible to disease-modifying treatment, really exists. Observational studies are most frequently referenced as supporting evidence, but results of such studies are subject to confounding. In addition formal (...) first description 25 years ago. There is an 'old definition' pointing to the first 2 years after diagnosis with increased potential for disease-modifying treatment to prevent severe radiographic damage and disability. Strong evidence supports this concept. A 'new definition' presumes a therapeutic window in a pre-RA phase in which the biologic processes could be halted and RA development prevented by very early treatment. This definition is not supported by evidence, although is less well studied

2020 RMD open PubMed abstract

175. Pedagogical principles and methods underpinning education of health and social care practitioners on experiences and needs of older LGBT+ people: Findings from a systematic review. (Abstract)

Pedagogical principles and methods underpinning education of health and social care practitioners on experiences and needs of older LGBT+ people: Findings from a systematic review. There is a growing awareness of the need for LGBT + competency training to ensure that the health and social care services offered to older LGBT + people is affirmative and gender sensitive.To conduct a synthesis of the literature that describes the pedagogical principles, curriculum content and methods (teaching (...) and experiences of older LGBT + people.The combined searches yielded 2214 papers of which 17 papers were eligible for inclusion, 10 discussion papers and 7 evaluation studies. Analysis identified the following themes: i) Acknowledging the wider historical context of older LGBT + people's lives; ii) Recognising that older LGBT + people are not a homogenous group; iii) Incorporating a multitude of theories and models from different perspectives; iv) Alerting practitioners to the health issues and disparities

2020 Nurse education in practice

176. Association between Vitamins and Minerals with Antioxidant Effects and Coronary Artery Calcification in Adults and Older Adults: A Systematic Review. (Abstract)

, its association with antioxidants remains unclear.This study aimed to systematically review the association between vitamins and minerals with antioxidant effects and CAC in adults and older adults.We conducted a systematic review using PubMed for articles published until October 2018. We included studies conducted in subjects aged 18 years and older with no previous cardiovascular disease. Studies involving animal or in vitro experiments and the ones that did not use reference methods to assess (...) Association between Vitamins and Minerals with Antioxidant Effects and Coronary Artery Calcification in Adults and Older Adults: A Systematic Review. Coronary Artery Calcification (CAC) is considered an important cardiovascular risk factor. There is evidence that CAC is associated with an increased risk of atherosclerosis, coronary events and cardiovascular mortality. Inflammation is one of the factors associated with CAC and despite the interest in antioxidant compounds that can prevent CAC

2020 Current pharmaceutical design

177. Geriatric Assessment and Frailty Scores Predict Mortality in Myeloma: Systematic Review and Meta-analysis. (Abstract)

Geriatric Assessment and Frailty Scores Predict Mortality in Myeloma: Systematic Review and Meta-analysis. The incidence of multiple myeloma is increasing as the proportion of older adults is growing rapidly. A critical evaluation of the evidence available is needed to guide the management of older patients with myeloma. A systematic review was conducted to report the prognostic value of geriatric assessment and frailty scores in older patients with multiple myeloma. We conducted a literature (...) search in February and August 2018. Two researchers extracted the data and assessed the quality of the studies. Geriatric assessment and frailty scores were defined as those evaluating at least 2 geriatric domains. Main outcomes were mortality or toxicity. We estimated the pooled hazard ratios (HR) with 95% confidence intervals (CIs) using a random-effects model. We screened titles and abstracts of 1672 citations for eligibility. Seven studies were included in the qualitative analysis, of which 3

2020 Clinical lymphoma, myeloma & leukemia

178. Association of age at menopause and type 2 diabetes: A systematic review and dose-response meta-analysis of cohort studies. (Abstract)

Association of age at menopause and type 2 diabetes: A systematic review and dose-response meta-analysis of cohort studies. Early age at menopause has been associated with increased incidence of type 2 diabetes mellitus (T2DM), but the quantitative association between age at menopause and T2DM was unclear. We performed a meta-analysis to assess the dose-response association between age at menopause and T2DM.PubMed, Embase and Web of Science were searched up to January 5, 2019 for cohort studies (...) that evaluated the association of age at menopause and risk of T2DM. Relative risks (RRs) and 95% confidence intervals (95% CIs) were pooled by using the random-effects models. Restricted cubic spline model was used to evaluate the liner or nonlinear relation.We identified 6 studies for the meta-analysis (267,284 women and 19,654 cases of T2DM). The pooled RR was 0.64 (95% CI 0.44-0.94) comparing the latest with the earliest category of age at menopause. The risk of T2DM was reduced by 10% (RR=0.90, 95% CI

2020 Primary care diabetes

179. Novel Targeted Therapies for Chronic Lymphocytic Leukemia in Elderly Patients: A Systematic Review. (Abstract)

Novel Targeted Therapies for Chronic Lymphocytic Leukemia in Elderly Patients: A Systematic Review. Chronic lymphocytic leukemia (CLL) typically affects older patients; administration of traditional cytotoxic therapies in old patients has very modest benefit with no survival improvement. With better understanding of CLL biology, trends are shifting towards the use of targeted therapies. The objective of this article is to review the safety and efficacy of various novel agents that specifically (...) target the dysregulated pathways, with particular attention to elderly patients. Agents like B-cell receptor (BCR) inhibitors (Bruton's tyrosine kinase inhibitors [ibrutinib]), phosphatidylinositol 3-kinase inhibitors (idelalisib), spleen tyrosine kinase inhibitors (entospletinib), Bcl-2 inhibitors (venetoclax), immunomodulators (lenalidomide), and monoclonal antibodies (obinutuzumab, ofatumumab) have shown activity in CLL with a very favorable toxicity profile. Newer agents have improved clinical

2020 Clinical lymphoma, myeloma & leukemia

180. Shared decision making in older patients with symptomatic severe aortic stenosis: a systematic review. (Abstract)

Shared decision making in older patients with symptomatic severe aortic stenosis: a systematic review. This review provides an overview of the status of shared decision making (SDM) in older patients regarding treatment of symptomatic severe aortic stenosis (SSAS). The databases Embase, Medline Ovid, Cinahl and Cochrane Dare were searched for relevant studies from January 2002 to May 2018 regarding perspectives of professionals, patients and caregivers; aspects of decision making; type (...) analysis, personalised treatment aims, use of decision aids and integrating patient goals in decisions lacked in all studies. Barriers to and facilitators of SDM were 'individualised formal and informal information support' and 'patients' opportunity to use their own knowledge about their health condition and preferences for SDM'. In conclusion, SDM is not yet common practice in the decision making process of older patients with SSAS. Moreover, the six domains of SDM are not often applied

2020 Heart (British Cardiac Society)