Latest & greatest articles for endometriosis

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Top results for endometriosis

1. Painful endometriosis: initial treatment options

Painful endometriosis: initial treatment options Prescrire IN ENGLISH - Spotlight ''Painful endometriosis: initial treatment options'', 1 March 2020 {1} {1} {1} | | > > > Painful endometriosis: initial treatment options Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Painful endometriosis: initial treatment options In the absence of urinary (...) or intestinal symptoms, and if the patient is not planning to become pregnant any time soon, first try analgesics such as NSAIDs or paracetamol. Hormonal contraception or a levonorgestrel intrauterine device are other options. Endometriosis, i.e. the abnormal presence of clumps of uterine mucous membrane cells outside the uterus, is a frequent cause of pelvic pain during menstruation. In some women, endometriosis is very painful and debilitating. Endometriosis does not appear to get worse over time

2020 Prescrire

2. Impact of haemostatic sealant versus electrocoagulation on ovarian reserve after laparoscopic ovarian cystectomy of ovarian endometriomas: a randomised controlled trial Full Text available with Trip Pro

Impact of haemostatic sealant versus electrocoagulation on ovarian reserve after laparoscopic ovarian cystectomy of ovarian endometriomas: a randomised controlled trial To evaluate the effect of haemostatic sealant compared with bipolar coagulation on ovarian reserve after laparoscopic cystectomy for ovarian endometriomas.Patient-blinded, randomised controlled trial.University-affiliated tertiary hospital.Women aged 18-40 years with 3-8 cm unilateral or bilateral endometriomas.Ninety-four (...)  ± 4.92 years underwent laparoscopic cystectomy for ovarian endometriomas. The average diameter of the endometrioma was 4.21 ± 1.38 cm. The increase in antral follicle count of the affected ovaries at 3 months in the intervention group (+2.36 ± 0.37) was significantly (P = 0.013) higher than that in the control group (+1.08 ± 0.36). Repeated measures analysis of variance revealed significant effect with time (P < 0.001) and of interaction of group × time (P = 0.029) for affected ovary antral follicle

2019 EvidenceUpdates

3. Elagolix (Orilissa) - for the treatment of moderate to severe pain associated with endometriosis

Elagolix (Orilissa) - for the treatment of moderate to severe pain associated with endometriosis Search Page - Drug and Health Product Register Language selection Search and menus Search Search website Search Topics menu You are here: Summary Basis of Decision - - Health Canada Expand all Summary Basis of Decision (SBD) for Contact: Summary Basis of Decision (SBD) documents provide information related to the original authorization of a product. The for is located below. Recent Activity for SBDs

2019 Health Canada - Drug and Health Product Register

4. Endometriosis

Endometriosis Endometriosis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Search Select language Endometriosis Last reviewed: December 2019 Last updated: March 2019 Summary Chronic inflammatory condition defined by endometrial stroma and glands found outside of the uterine cavity. The most common sites affected are the pelvic peritoneum and ovaries. May present incidentally in asymptomatic patients, or more (...) ), and surgical destruction of lesions. Controlled ovarian hyper-stimulation and IVF may be considered for patients with sub-fertility. Individualised care for patients with pelvic pain should incorporate a multi-disciplinary evaluation and treatment plan that focuses on limiting the risk of recurrence and improving quality of life. Definition Endometriosis is defined as the presence of endometrial glands and stroma outside the endometrial cavity and uterine musculature. Surgical appearance varies

2019 BMJ Best Practice

5. Baseline severe constipation negatively impacts functional outcomes of surgery for deep endometriosis infiltrating the rectum: Results of the ENDORE randomized trial. (Abstract)

Baseline severe constipation negatively impacts functional outcomes of surgery for deep endometriosis infiltrating the rectum: Results of the ENDORE randomized trial. Predictive factors of functional outcomes after the surgery of rectal endometriosis are not well identified. Our recent randomized trial did not find significant differences between functional outcomes in patients managed by radical or conservative rectal surgery.To identify preoperative factors which determine functional outcomes (...) measures was used to assess whether a trend could be observed over the follow-up period as regards gastrointestinal and quality of life scores.60 patients with deep endometriosis infiltrating the rectum were managed by conservative surgery (27 cases) and segmental colorectal resection (33 cases). The primary endpoint was recorded in 26 patients (48.1% for conservative surgery vs. 39.4% for radical surgery, OR = 0.70, 95% CI 0.22-2.21). There was a significant improvement in values of all

2019 Journal of gynecology obstetrics and human reproduction Controlled trial quality: predicted high

6. Dysmenorrhea and Endometriosis in the Adolescent

for endometriosis in adolescents is conservative surgical therapy for diagnosis and treatment combined with ongoing suppressive medical therapies to prevent endometrial proliferation. Patients with endometriosis who have pain refractory to conservative surgical therapy and suppressive hormonal therapy often benefit from at least 6 months of gonadotropin-releasing hormone (GnRH) agonist therapy with add-back medicine. Nonsteroidal antiinflammatory drugs should be the mainstay of pain relief for adolescents (...) in adolescents requiring the presence of endometrial glands and stroma in the biopsy specimen from a location outside of the endometrial cavity. Patients with persistent dysmenorrhea despite treatment and no other identified etiologies should be counseled about the high likelihood of endometriosis and the risks and benefits of diagnostic laparoscopy. The benefits of laparoscopy include confirmation of the presence or absence of endometriosis or other causes of chronic pain such as adhesive disease

2019 American College of Obstetricians and Gynecologists

7. Transversus abdominis plane block under laparoscopic guide versus port-site local anaesthetic infiltration in laparoscopic excision of endometriosis: a double-blind randomised placebo-controlled trial (Abstract)

Transversus abdominis plane block under laparoscopic guide versus port-site local anaesthetic infiltration in laparoscopic excision of endometriosis: a double-blind randomised placebo-controlled trial To compare the efficiency of laparoscopically guided transversus abdominis plane block (LTAP) versus port-site local anaesthetic infiltration (LAI) in reducing postoperative pain following laparoscopic excision of endometriosis.A prospective, double-blind randomised controlled trial.A tertiary (...) referral centre for endometriosis and minimally invasive gynaecological surgery.Women undergoing laparoscopic excision of endometriosis from December 2015 through July 2016.Participants were randomised to receive: port-site infiltration with bupivacaine and placebo LTAP (LAI group, n = 21); placebo port-site infiltration and LTAP with bupivacaine (LTAP group, n = 24); placebo port-site infiltration and placebo LTAP (placebo group, n = 25).Post-operative pain at 2-4, 6-8, 10-12 and 24 hours, analgesic

2019 EvidenceUpdates

8. Renal Endometriosis: The Case of an Endometrial Implant Mimicking a Renal Mass Full Text available with Trip Pro

Renal Endometriosis: The Case of an Endometrial Implant Mimicking a Renal Mass Background: Endometriosis is a multifactorial benign disorder characterized by the abnormal presence of endometrial tissue in an extraendometrial site. Although extrapelvic endometriosis is uncommon, symptomatic involvement of the kidney is exceedingly rare. This benign disease can mimic several urologic processes, but because of its scarcity in clinical practice, it is seldom considered in the differential. Case (...) Presentation: In this report, we describe the case of a 45-year-old woman with flank pain and hematuria, who was found to have a left renal mass on cross-sectional imaging. After robotic partial nephrectomy, pathologic analysis revealed an endometrial implant within the renal parenchyma. Conclusion: This case of renal endometriosis highlights how this benign disease process can mimic several more sinister urologic processes.

2018 Journal of endourology case reports

9. MRI-Ultrasound Fusion Imaging for Diagnosis of Deep Infiltrating Endometriosis – A Critical Appraisal Full Text available with Trip Pro

MRI-Ultrasound Fusion Imaging for Diagnosis of Deep Infiltrating Endometriosis – A Critical Appraisal It was the aim of our study to evaluate this procedure using pelvic anatomical landmarks in order to assess the accuracy of fusion imaging and to critically evaluate the applicability in daily practice.In a prospective, single center study, 10 patients with clinical signs of deep infiltrating endometriosis (DIE) were selected. We measured the distance between the landmark organ and the target

2018 Ultrasound international open

10. Elagolix sodium (Orilissa) - For the management of moderate to severe pain associated with endometriosis

Elagolix sodium (Orilissa) - For the management of moderate to severe pain associated with endometriosis Drug Approval Package: Orilissa (elagolix sodium) U.S. Department of Health and Human Services Search FDA Submit search Drug Approval Package: Orilissa (elagolix sodium) Company: AbbVie Inc. Application Number: 210450 Approval Date: 07/23/2018 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. FDA Approval Letter and Labeling (PDF

2018 FDA - Drug Approval Package

11. Endometriosis

/terms-and- conditions#notice-of-rights). Page 2 of 25Contents Contents Overview 4 Who is it for? 4 Recommendations 5 1.1 2017 2. Recommendations for surgical treatment of endometriosis . Part 1: Ovarian Endometrioma Recommendations for the Surgical Treatment of Endometriosis . Part 1: Ovarian Endometrioma †‡¶ | Human Reproduction Open | Oxford Academic We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change (...) your cookie settings at any time. Search Account Menu Menu Navbar Search Filter Mobile Microsite Search Term Close search filter (...) search input Article Navigation Close mobile search navigation Article navigation 2017 Article Contents Article Navigation Recommendations for the Surgical Treatment of Endometriosis . Part 1: Ovarian Endometrioma Working group of ESGE, ESHRE and WES Search for other works by this author on: Ertan Saridogan Institute for Women's Health , University College Hospital

2018 Trip Latest and Greatest

12. Elagolix for Treating Endometriosis

for Treating Endometriosis Return to Table of Contents Executive Summary Background Endometriosis is a chronic gynecological condition characterized by the attachment and proliferation of endometrial-like tissue outside of the uterus. 1 Endometriosis affects 6-10% of women of reproductive age, with peak prevalence between 25 to 35 years of age, and is estimated to affect four to 10 million women in the United States. 2-4 Common symptoms of endometriosis include painful menstrual periods, nonmenstrual (...) they should be in removing observed endometrial-like tissue. • Studies have shown that adding hormonal therapy after surgery results in better pain control than surgery alone, but have included newer, more aggressive approaches. 21 Elagolix is a novel agent, but enthusiasm is muted because it still works by lowering hormone levels. • Elagolix is the first new FDA approved drug for endometriosis in over 20 years, but it highlights a lack of research focused on a basic understanding of what causes

2018 California Technology Assessment Forum

13. Inhibitory effect of traditional Korean medicine on the recurrent endometriosis after laparoscopic excision: a case report Full Text available with Trip Pro

Inhibitory effect of traditional Korean medicine on the recurrent endometriosis after laparoscopic excision: a case report Endometriosis is a common benign gynecologic tumor, and it can destroy a patient's life. Surgery and hormone therapy are established therapies for endometriosis. However, there are many cases of recurrent endometriosis after conventional therapies. This report presents a case of a patient who has repetitive recurrence of endometriosis after laparoscopic excision and hormone (...) therapy. A 32-years-old female patient first had laparoscopic surgery to remove endometriosis in 2011. The disease recurred two more times after the first excision. Hormone therapy by dienogest and two more laparoscopic surgeries were done in 2012 and 2014. With acupuncture, moxibustion, fumigation therapy, and herbal medicine therapy, endometriosis didn't recur during treatment and observation period of 34 months. Menstrual pain numeric rating scales (NRS) decreased from 2 to none. Shortened

2018 Integrative medicine research

14. Elagolix for Treating Endometriosis

adverse event SRDR Systematic Review Data Repository VAS Visual Analogue Scale ©Institute for Clinical and Economic Review, 2018 Page ES 1 Evidence Report – Elagolix for Treating Endometriosis Return to Table of Contents Executive Summary Background Endometriosis is a chronic gynecological condition characterized by the attachment and proliferation of endometrial-like tissue outside of the uterus. 1 Endometriosis affects 6-10% of women of reproductive age, with peak prevalence between 25 to 35 years (...) uncertainty about the optimal surgical procedures, especially how aggressive they should be in removing observed endometrial-like tissue. • Studies have shown that adding hormonal therapy after surgery results in better pain control than surgery alone, but have included newer, more aggressive approaches. 20 Elagolix is a novel agent, but enthusiasm is muted because it still works by lowering hormone levels. • Elagolix may be the first new FDA approved drug for endometriosis in over 20 years

2018 California Technology Assessment Forum

15. Notch-1 Signaling Activation and Progesterone Receptor Expression in Ectopic Lesions of Women With Endometriosis Full Text available with Trip Pro

(United States, Taiwan).Women with endometriosis; human endometrial stromal cell line (HESC).Eutopic endometria (EU) and ectopic lesions (ECs) were collected from surgically diagnosed patients. Archived tissue sections of EU and ECs were identified. HESCs were treated with N-[N-(3,5-difluorophenacetyl)-l-alanyl]-S-phenylglycine t-butyl ester (DAPT) and valproic acid (VPA) to, respectively, suppress and induce Notch-1 activation.Tissues were analyzed for Notch Intra-Cellular Domain 1 (NICD1 (...) Notch-1 Signaling Activation and Progesterone Receptor Expression in Ectopic Lesions of Women With Endometriosis Progesterone (P) resistance is a hallmark of endometriosis, but the underlying mechanism(s) for loss of P sensitivity leading to lesion establishment remains poorly understood.To evaluate the association between Notch-1 signaling activation and P resistance in the progression of endometriosis.Case control study; archived formalin-fixed, paraffin-embedded tissues.University hospitals

2018 Journal of the Endocrine Society

16. Oral contraceptives for pain associated with endometriosis. Full Text available with Trip Pro

Oral contraceptives for pain associated with endometriosis. Endometriosis is a common gynaecological condition which affects many women of reproductive age worldwide and is a major cause of pain and infertility. The combined oral contraceptive pill (COCP) is widely used to treat pain occurring as a result of endometriosis, although the evidence for its efficacy is limited.To determine the effectiveness, safety and cost-effectiveness of oral contraceptive preparations in the treatment of painful (...) handsearched reference lists of relevant trials and systematic reviews retrieved by the search.We included randomised controlled trials (RCT) of the use of COCPs in the treatment of women of reproductive age with symptoms ascribed to the diagnosis of endometriosis that had been made visually at a surgical procedure.Two review authors independently assessed study quality and extracted data. One review author was an expert in the content matter. We contacted study authors for additional information

2018 Cochrane

17. Recommendations for surgical treatment of endometriosis. Part 1: Ovarian Endometrioma Full Text available with Trip Pro

. The endoscopic localization of endometrial implants in the ovarian chocolate cyst . Fertil Steril 1994 ; 61 : 1034 – 1038 . Burney RO , Giudice LC . Pathogenesis and pathophysiology of endometriosis . Fertil Steril 2012 ; 98 : 511 – 519 . Busacca M , Vignali M . Ovarian endometriosis: from pathogenesis to surgical treatment . Curr Opin Obstet Gynecol 2003 ; 15 : 321 – 326 . Chapron C , Pietin-Vialle C , Borghese B , Davy C , Foulot H , Chopin N . Associated ovarian endometrioma is a marker for greater (...) Recommendations for surgical treatment of endometriosis. Part 1: Ovarian Endometrioma We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. Recommendations for the Surgical Treatment of Endometriosis. Part 1: Ovarian Endometrioma†‡¶ | Human Reproduction Open | Oxford Academic Search Account Menu Menu Navbar Search Filter Mobile Microsite Search Term Close search filter

2018 European Society of Human Reproduction and Embryology

18. Management of endometriosis

guidelines was developed by the French National Authority for Health (HAS) and the French College of Gynaecologists and Obstetricians (CNGOF) to update the 2006 CNGOF guideline on the management of endometriosis. The purpose of this guide is to help hospital and community based healthcare professionals offer patients the best possible information and management. This guideline deals with the diagnosis and management of peritoneal, ovarian and deep endometriosis. The management of adenomyosis (...) Management of endometriosis Haute Autorité de Santé - Management of endometriosis Fermer Choose language Accessibility Change contrast : Standards Reinforced icone Chercher icone plus Chercher My account My account Please fill in your email address to retrieve your email alerts subscriptions. Please fill in your email address to retrieve your newsletter subscriptions. You do not have a saved search Sélection No element in selection Services Services Déclarer un événement indésirable grave

2018 HAS Guidelines

19. Endometriosis factsheet

diagnosed. Endometriosis can often be confused with or misdiagnosed as IBS (irritable bowel syndrome). It is important that women receive a early diagnosis, or working diagnosis, of endometriosis even if hormonal treatments appear to be working, as women need to understand that they have a long term, chronic condition and the impact this might have on their future and their fertility. What is endometriosis? Endometriosis is defined as the presence of endometrial-like tissue outside the uterus, which (...) arrangements and seek advice from an endometriosis clinical nurse specialist: • if there is uncertainty over the diagnosis • if a women requests referral • if the woman has fertility problems • if surgical and medical management of endometriosis is required6 • if complex/severe endometriosis is suspected – for example, endometriomas or where endometriosis is affecting the bowel (Quality Standard 2018) • if initial hormonal treatment for endometriosis is not effective, not tolerated or contraindicated (NICE

2018 Royal College of Nursing

20. Endometriosis

Endometriosis Endometriosis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Endometriosis Last reviewed: February 2019 Last updated: March 2019 Summary Chronic inflammatory condition defined by endometrial stroma and glands found outside of the uterine cavity. The most common sites affected are the pelvic peritoneum and ovaries. May present incidentally in asymptomatic patients, or more commonly in women (...) of lesions. Controlled ovarian hyper-stimulation and IVF may be considered for patients with sub-fertility. Individualised care for patients with pelvic pain should incorporate a multi-disciplinary evaluation and treatment plan that focuses on limiting the risk of recurrence and improving quality of life. Definition Endometriosis is defined as the presence of endometrial glands and stroma outside the endometrial cavity and uterine musculature. Surgical appearance varies significantly from superficial

2018 BMJ Best Practice