Latest & greatest articles for endometriosis

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Top results for endometriosis

61. Guideline on the management of women with endometriosis

value of markers retrieved from endometrial tissue, menstrual fluid or uterine fluid to diagnose endometriosis in a non-invasive way. All 182 studies had visual and/or histological confirmation of endometriosis after laparoscopy or laparotomy, defined as the presence of peritoneal endometriotic lesions, endometrioma and/or rectovaginal endometriotic nodules (May, et al., 2011). The overall conclusions of the authors were: 1) nine studies of high quality were identified, 2) in 32 studies sensitivity (...) versus excision of endometriosis 40 2.4.3 Surgical interruption of pelvic nerve pathways 41 2.4.4 Surgery for treatment of pain associated with ovarian endometrioma 42 2.4.5 Surgery for treatment of pain associated with deep endometriosis 43 2.4.6 Hysterectomy for endometriosis-associated pain 45 2.4.7 Adhesion prevention after endometriosis surgery 46 2.5 Preoperative hormonal therapies for treatment of endometriosis-associated pain 48 2.6 Postoperative hormonal therapies for treatment

2013 European Society of Human Reproduction and Embryology

62. Uterine artery embolisation for treating adenomyosis (IPG473)

, in December, 2013. Description Adenomyosis is a benign condition characterised by the presence of ectopic endometrial glands and stroma within the myometrium. It frequently occurs coincidentally with fibroids. Adenomyosis may cause no symptoms but some women with adenomyosis experience heavy, prolonged menstrual bleeding with severe cramps, pelvic pain and discomfort. Treatment for symptomatic adenomyosis includes anti-inflammatory medications, hormone therapy and endometrial ablation. For severe symptoms (...) Uterine artery embolisation for treating adenomyosis (IPG473) Overview | Uterine artery embolisation for treating adenomyosis | Guidance | NICE Uterine artery embolisation for treating adenomyosis Interventional procedures guidance [IPG473] Published date: December 2013 Share Save Guidance The National Institute for Health and Care Excellence (NICE) issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on Uterine Artery Embolisation for treating adenomyosis

2013 National Institute for Health and Clinical Excellence - Interventional Procedures

63. Dienogest - Pain (pelvic) associated with endometriosis

Dienogest - Pain (pelvic) associated with endometriosis Common Drug Review CDEC Meeting – March 21, 2012 Notice of CDEC Final Recommendation – April 19, 2012 Page 1 of 4 © 2012 CADTH CDEC FINAL RECOMMENDATION DIENOGEST (Visanne – Bayer Inc.) Indication: Management of Pelvic Pain Associated With Endometriosis Recommendation: The Canadian Drug Expert Committee (CDEC) recommends that dienogest be listed for the management of pelvic pain associated with endometriosis in patients for whom one (...) or more less costly hormonal options are either ineffective or cannot be used. Reasons for the Recommendation: 1. In two randomized controlled trials (RCTs) included in the systematic review, dienogest was superior to placebo (study A32473), and non-inferior to leuprolide (study AU19), in reducing pelvic pain in patients with endometriosis. 2. At the submitted price, the daily drug cost of dienogest ($1.96) is less than all alternatives with a Health Canada indication for the treatment or hormonal

2012 Canadian Agency for Drugs and Technologies in Health - Common Drug Review

64. Postoperative levonorgestrel-releasing intrauterine system for pelvic endometriosis-related pain: a randomized controlled trial Full Text available with Trip Pro

Postoperative levonorgestrel-releasing intrauterine system for pelvic endometriosis-related pain: a randomized controlled trial To estimate the effectiveness of a postoperative levonorgestrel-releasing intrauterine system for relieving pelvic pain in patients with endometriosis.A double-blind randomized controlled trial was conducted in 55 patients with endometriosis and moderate-to-severe dysmenorrhea (visual analog scale, greater than 50 mm) undergoing laparoscopic conservative surgery. After (...) accepted for long-term therapy after conservative surgery for patients with moderate to severe pain related to endometriosis. It can improve the patient's quality of life, including physical and mental health.

2012 EvidenceUpdates Controlled trial quality: predicted high

65. Endometriosis and infertility: a committee opinion

to awomanundergoingIVFforanotherindication,forexample, tubal factor infertility. For infertile women with ASRM stage III/IV endometri- osis and no other identi?able infertility factor, conservative surgery with laparoscopy and/or possible laparotomy or IVF are recommended (28). Although not evaluated with RCTs, observational studies suggest that surgical therapy increases fertility in women with advanced endometriosis, thus discouraging expectant management. For women who are found to have an asymptomatic endometrioma and who (...) % of infertile women have endo- metriosis and that 30% to 50% of women with endometriosis are infertile (1).Thetrueprevalenceofendometriosis is dif?cult to quantify as very wide ranges have been reported in the litera- ture. One study suggested the preva- lence of endometriosis in women who undergo tubal sterilization is 1% to 7%, while the prevalence of endometri- osisinwomenundergoingalaparoscopy forevaluationofinfertilityis9%to50% (1, 2). Among women with pelvic pain the prevalence of endometriosis ranges

2012 Society for Assisted Reproductive Technology

66. [Effectiveness and safety of the HELICA technique in the treatment of endometriosis. Systematic review of the literature]

[Effectiveness and safety of the HELICA technique in the treatment of endometriosis. Systematic review of the literature] Efectividad y seguridad de la tecnica HELICA en el tratamiento de la endometriosis [Effectiveness and safety of the HELICA technique in the treatment of endometriosis. Systematic review of the literature] Efectividad y seguridad de la tecnica HELICA en el tratamiento de la endometriosis [Effectiveness and safety of the HELICA technique in the treatment of endometriosis (...) . Systematic review of the literature] Llanos Mendez A Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Llanos Mendez A. Efectividad y seguridad de la tecnica HELICA en el tratamiento de la endometriosis. [Effectiveness and safety of the HELICA technique in the treatment of endometriosis. Systematic review of the literature] Seville: Andalusian Agency

2011 Health Technology Assessment (HTA) Database.

67. Bowel resection for deep endometriosis: a systematic review

Bowel resection for deep endometriosis: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2011 DARE.

68. Acupuncture for pain in endometriosis. Full Text available with Trip Pro

Acupuncture for pain in endometriosis. Endometriosis is a prevalent gynaecological condition, significantly affecting women's lives. Clinical presentations may vary from absence of symptoms to complaints of chronic pelvic pain, most notably dysmenorrhoea. The management of pain in endometriosis is currently inadequate. Acupuncture has been studied in gynaecological disorders but its effectiveness for pain in endometriosis is uncertain.To determine the effectiveness and safety of acupuncture (...) for pain in endometriosis. We searched the Cochrane Menstrual Disorders and Subfertility Group (MSDG) Specialised Register of controlled trials, Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library), MEDLINE, EMBASE, CINAHL, AMED, PsycINFO, CNKI and TCMDS (from inception to 2010) and reference lists of retrieved articles.Randomised single or double-blind controlled trials enrolling women of reproductive age with a laparoscopically confirmed diagnosis of endometriosis

2011 Cochrane

69. Urinary dysfunction after colorectal resection for endometriosis: results of a prospective randomized trial comparing laparoscopy to open surgery (Abstract)

Urinary dysfunction after colorectal resection for endometriosis: results of a prospective randomized trial comparing laparoscopy to open surgery To evaluate urinary symptoms before and after colorectal resection for endometriosis using validated questionnaires.We randomly assigned 52 patients with colorectal endometriosis to undergo laparoscopically assisted or open colorectal resection. The median follow-up was 19 months. Urinary symptoms were evaluated using the International Prostate Score (...) not undergo nerve sparing surgery (P = .048). An alteration of the International Prostate Score Symptom voiding symptoms was observed for patients who underwent vaginal resection (P = .01) and parametrial resection (P = .02).Our findings confirm that colorectal resection for endometriosis is a source of urinary dysfunction whatever the surgical route.Copyright © 2011 Mosby, Inc. All rights reserved.

2011 EvidenceUpdates Controlled trial quality: uncertain

70. Chinese herbal medicine may be beneficial in endometriosis

Chinese herbal medicine may be beneficial in endometriosis PEARLS Practical Evidence About Real Life Situations PEARLS are succinct summaries of Cochrane Systematic Reviews for primary care practitioners. They Chinese herbal medicine may be beneficial in endometriosis Clinical question How effective is Chinese herbal medicine (CHM) in alleviating endometriosis-related pain and infertility? Bottom line Following laparoscopic surgery, combined oral and enema administration of CHM has a comparable (...) beneficial effect to gestrinone but with fewer adverse effects. Oral and enema administration of CHM may be more effective than danazol in providing extended relief of endometriosis symptoms (NNT* 2) and in shrinking adnexal masses, with fewer adverse effects. For lumbosacral pain, rectal discomfort, or vaginal nodules tenderness, there was no significant difference either between CHM and danazol. *NNT = number needed to treat to benefit 1 individual. Note that no range is given as there were only 2

2011 Cochrane PEARLS

71. Endometriosis-associated ovarian carcinomas. Full Text available with Trip Pro

Endometriosis-associated ovarian carcinomas. 21288104 2011 02 10 2018 05 10 1533-4406 364 5 2011 02 03 The New England journal of medicine N. Engl. J. Med. Endometriosis-associated ovarian carcinomas. 483-4; author reply 484-5 10.1056/NEJMc1012780 Birnbaum David J DJ Birnbaum Daniel D Bertucci François F eng Letter Comment United States N Engl J Med 0255562 0028-4793 0 ARID1A protein, human 0 ARID1B protein, human 0 DNA-Binding Proteins 0 Nuclear Proteins 0 Transcription Factors AIM IM N Engl J (...) Med. 2010 Oct 14;363(16):1532-43 20942669 DNA-Binding Proteins genetics Endometriosis complications Female Humans Mutation Nuclear Proteins genetics Ovarian Neoplasms genetics Pancreatic Neoplasms genetics Transcription Factors genetics 2011 2 4 6 0 2011 2 4 6 0 2011 2 11 6 0 ppublish 21288104 10.1056/NEJMc1012780 10.1056/NEJMc1012780#SA2

2011 NEJM

72. Endometriosis-associated ovarian carcinomas. Full Text available with Trip Pro

Endometriosis-associated ovarian carcinomas. 21288105 2011 02 10 2018 05 10 1533-4406 364 5 2011 02 03 The New England journal of medicine N. Engl. J. Med. Endometriosis-associated ovarian carcinomas. 482-3; author reply 484-5 10.1056/NEJMc1012780 Nissenblatt Michael M eng Letter Comment United States N Engl J Med 0255562 0028-4793 0 ARID1A protein, human 0 Nuclear Proteins 0 Transcription Factors AIM IM N Engl J Med. 2010 Oct 14;363(16):1532-43 20942669 Adenocarcinoma, Clear Cell genetics (...) Carcinoma, Endometrioid genetics Endometriosis complications Fallopian Tubes cytology Female Humans Mullerian Ducts embryology Mutation Nuclear Proteins genetics Ovarian Neoplasms genetics pathology Ovary embryology Transcription Factors genetics 2011 2 4 6 0 2011 2 4 6 0 2011 2 11 6 0 ppublish 21288105 10.1056/NEJMc1012780 10.1056/NEJMc1012780#SA1

2011 NEJM

74. Oral contraceptives and risk of endometriosis: a systematic review and meta-analysis

Oral contraceptives and risk of endometriosis: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2011 DARE.

75. Hormonal treatment for endometriosis associated pelvic pain

Hormonal treatment for endometriosis associated pelvic pain Hormonal treatment for endometriosis associated pelvic pain Hormonal treatment for endometriosis associated pelvic pain Wong WS, Lim CE CRD summary The review concluded that it appeared that combined oral contraceptive pills, gonadotrophin-releasing hormone analogues and progestogens were all effective and well tolerated by patients in treating endometriosis-associated pain, but side effects had to be considered. The review had some (...) methodological problems and data limitations that limit the reliability of the authors’ conclusions. Authors' objectives To evaluate the effectiveness of hormonal treatments of endometriosis associated pain in women of reproductive age. Searching MEDLINE and Cochrane Database of systematic reviews were searched from 1995 to 2009 for articles in English. Search terms were reported. Study selection Randomised controlled trials (RCTs) of medical treatments aimed at improving symptomatic endometriosis-associated

2011 DARE.

76. Interventions for women with endometrioma prior to assisted reproductive technology. (Abstract)

Interventions for women with endometrioma prior to assisted reproductive technology. Endometriomata are cysts of endometriosis in the ovaries. As artificial reproductive technology (ART) cycles involve oocyte pickup from the ovaries, endometriomata may interfere with the outcome of ART.To determine the effectiveness and safety of surgery, medical treatment, combination therapy or no treatment for improving reproductive outcomes among women with endometriomata, prior to undergoing ART cycles.The (...) or the NMOR.There was no evidence of an effect on reproductive outcomes in any of the four included trials. Further RCTs of management of endometrioma in women undergoing ART are required.

2010 Cochrane

77. ARID1A mutations in endometriosis-associated ovarian carcinomas. Full Text available with Trip Pro

ARID1A mutations in endometriosis-associated ovarian carcinomas. Ovarian clear-cell and endometrioid carcinomas may arise from endometriosis, but the molecular events involved in this transformation have not been described.We sequenced the whole transcriptomes of 18 ovarian clear-cell carcinomas and 1 ovarian clear-cell carcinoma cell line and found somatic mutations in ARID1A (the AT-rich interactive domain 1A [SWI-like] gene) in 6 of the samples. ARID1A encodes BAF250a, a key component (...) of the BAF250a protein correlated strongly with the ovarian clear-cell carcinoma and endometrioid carcinoma subtypes and the presence of ARID1A mutations. In two patients, ARID1A mutations and loss of BAF250a expression were evident in the tumor and contiguous atypical endometriosis but not in distant endometriotic lesions.These data implicate ARID1A as a tumor-suppressor gene frequently disrupted in ovarian clear-cell and endometrioid carcinomas. Since ARID1A mutation and loss of BAF250a can be seen

2010 NEJM

79. Anti-TNF-alpha treatment for pelvic pain associated with endometriosis. (Abstract)

Anti-TNF-alpha treatment for pelvic pain associated with endometriosis. Endometriosis is a chronic, recurring condition that can develop during the reproductive years. It is characterized by the development of endometrial tissue outside the uterine cavity. It is the most common cause of pelvic pain in women. This endometrial tissue development is dependent on estrogen produced primarily by the ovaries and, therefore, traditional management has focused on suppression of ovarian function (...) . The mounting evidence shows that altered immune function plays a crucial role in the genesis and development of endometriosis. In this review we considered modulating the inflammation as an alternative approach.To determine the effectiveness and safety of anti-tumour necrosis factor-alpha (anti-TNF-alpha) drugs in the management of pelvic pain associated with endometriosis.We searched for trials in the following databases (from their inception to August 2009): Cochrane Menstrual Disorders and Subfertility

2010 Cochrane

80. Endometriosis: Diagnosis and Management

Endometriosis: Diagnosis and Management Endometriosis: Diagnosis and Management - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 32, Issue 7, Supplement 2, Pages S1–S3 Endometriosis: Diagnosis and Management PRINCIPAL AUTHORS, x Nicholas Leyland , MD Toronto ON x Robert Casper , MD Toronto ON x Philippe Laberge , MD Quebec QC x Sukhbir S. Singh , MD Ottawa ON SPECIAL CONTRIBUTORS, x Lisa Allen , MD Toronto ON x (...) Lynn Wolfman , MD Toronto ON x Vyta Senikas , MD Ottawa, ON DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. Abstract Objective To improve the understanding of endometriosis and to provide evidence-based guidelines for the diagnosis and management of endometriosis. Outcomes Outcomes evaluated include the impact of the medical and surgical management of endometriosis on women’s experience of morbidity and infertility. Methods Members

2010 Society of Obstetricians and Gynaecologists of Canada