Latest & greatest articles for fatigue

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This page lists the very latest high quality evidence on fatigue and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for fatigue

201. Assessment and management of cancer-related fatigue in adults. (Abstract)

Assessment and management of cancer-related fatigue in adults. Fatigue is one of the most prevalent and distressing symptoms of cancer, and is a common side-effect of many of the treatments available for the management of malignant disease. We critically assess the evidence for cancer-related fatigue and its treatment in adults. Little is known about the cause and mechanisms of fatigue, and research into methods of alleviating the condition has focused on treatment for anaemia and behavioural (...) interventions, such as exercise, both of which are effective in reducing fatigue. Although research into the condition has increased considerably in the past decade, important gaps in knowledge remain.

2003 Lancet

202. Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial. Full Text available with Trip Pro

Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial. To determine the subjective response to iron therapy in non-anaemic women with unexplained fatigue.Double blind randomised placebo controlled trial.Academic primary care centre and eight general practices in western Switzerland.144 women aged 18 to 55, assigned to either oral ferrous sulphate (80 mg/day of elemental iron daily; n=75) or placebo (n=69) for four weeks.Level (...) of fatigue, measured by a 10 point visual analogue scale.136 (94%) women completed the study. Most had a low serum ferritin concentration; fatigue, depression, and anxiety were similar in both groups at baseline. Both groups were also similar for compliance and dropout rates. The level of fatigue after one month decreased by -1.82/6.37 points (29%) in the iron group compared with -0.85/6.46

2003 BMJ Controlled trial quality: predicted high

203. Psychological treatment of patients with chronic toxic encephalopathy: lessons from studies of chronic fatigue and whiplash

Psychological treatment of patients with chronic toxic encephalopathy: lessons from studies of chronic fatigue and whiplash Psychological treatment of patients with chronic toxic encephalopathy: lessons from studies of chronic fatigue and whiplash Psychological treatment of patients with chronic toxic encephalopathy: lessons from studies of chronic fatigue and whiplash van Hout M S, Wekking E M, Berg I J, Deelman B G CRD summary This review assessed the effectiveness of psychologically based (...) treatments for 'chronic toxic encephalopathy' (CTE), chronic whiplash-associated disorder and chronic fatigue syndrome. The authors concluded that cognitive-behaviour therapy plus graded activity may improve symptoms of CTE. The conclusions were based on a small number of studies and study quality was not systematically assessed, so the conclusions may not be reliable. Authors' objectives To assess the effect of (neuro)psychological treatments for chronic toxic encephalopathy (CTE) and the comparable

2003 DARE.

204. Sleep loss and fatigue in residency training: a reappraisal. (Abstract)

Sleep loss and fatigue in residency training: a reappraisal. Reduced sleep time is commonplace for many interns and residents. Recent studies, however, suggest that sleep loss and fatigue result in significant neurobehavioral impairments in healthy young adults. We reviewed studies addressing the effects of sleep loss on cognition, performance, and health in surgical and nonsurgical residents. We describe the effectiveness of countermeasures for sleepiness, including recent work-hour (...) restrictions. A more complete understanding of the issues of sleep loss during residency training can inform innovative strategies to minimize the effects of sleepiness and fatigue on patient care and resident safety.

2002 JAMA

205. Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction. (Abstract)

Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction. beta-Blocker therapy remains substantially underused in cardiac patients despite its proven mortality benefits. Reluctance to prescribe these agents may derive from concerns about their association with symptoms of depression, fatigue, and sexual dysfunction.To determine the association of beta-blockers with depressive symptoms, fatigue, and sexual dysfunction by performing a quantitative review of randomized (...) treatments, placebo control, noncrossover design, enrollment of at least 100 patients, and a minimum of 6 months of follow-up. The initial search produced 475 articles, 42 of which met these criteria. Fifteen of these trials reported on depressive symptoms, fatigue, or sexual dysfunction and were selected for inclusion.For each trial, 1 author abstracted the frequency of adverse events in the beta-blocker and placebo groups and the numbers of patients randomized to the treatment groups. Two other authors

2002 JAMA

206. Symptom Management in Cancer: Pain, Depression, and Fatigue

Symptom Management in Cancer: Pain, Depression, and Fatigue NIH State-of-the-Science Statement on Symptom Management in Cancer: Pain, Depression, and Fatigue NIH Consensus and State-of-the-Science Statements Volume 19, Number 4 July 15–17, 2002 NATIONAL INSTITUTES OF HEALTH Office of the Director About the NIH Consensus Development Program NIH Consensus Development and State-of-the-Science Conferences are convened to evaluate the available scientific evidence on a given biomedi­ cal or public (...) , and fatigue. NIH Consens State Sci Statements. 2002 Jul 15–17; 19(4) 1—29. Publications Ordering Information NIH Consensus Statements, State-of-the-Science Statements, and Technol­ ogy Assessment Statements and related materials are available by writing to the NIH Consensus Development Program Information Center, P.O. Box 2577, Kensington, MD 20891; by calling toll free 1-888-NIH-CONSENSUS (888-644-2667); or by visiting the NIH Consensus Development Program home page at http://consensus.nih.gov

2002 NIH Consensus Statements

207. Management of cancer symptoms: pain, depression and fatigue

Management of cancer symptoms: pain, depression and fatigue Management of cancer symptoms: pain, depression and fatigue Management of cancer symptoms: pain, depression and fatigue Carr D, Goudas L, Lawrence D Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Carr D, Goudas L, Lawrence D. Management of cancer symptoms: pain, depression (...) and fatigue. Rockville: Agency for Healthcare Research and Quality (AHRQ). Evidence Report/Technology Assessment No. 61. 2002 Authors' objectives Despite dramatic advances in cancer biology and a widening array of treatment options, cancer continues to cause devastating suffering not only in the hundreds of thousands of patients who die of it each year in the United States, but also in some patients who are successfully treated and become cancer survivors. This report was produced on request from

2002 Health Technology Assessment (HTA) Database.

208. Systematic review of the current literature related to disability and chronic fatigue syndrome

Systematic review of the current literature related to disability and chronic fatigue syndrome Systematic review of the current literature related to disability and chronic fatigue syndrome Systematic review of the current literature related to disability and chronic fatigue syndrome Ross S D, Levine C, Ganz N, Frame D, Estok R, Stone L, Ludensky V Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality (...) of this assessment has been made for the HTA database. Citation Ross S D, Levine C, Ganz N, Frame D, Estok R, Stone L, Ludensky V. Systematic review of the current literature related to disability and chronic fatigue syndrome. Rockville: Agency for Healthcare Research and Quality (AHRQ). Evidence Report/Technology Assessment No. 66. 2002 Authors' objectives The objective of this evidence report was to perform a systematic review of the published literature to provide the Social Security Administration (SSA

2002 Health Technology Assessment (HTA) Database.

209. The effectiveness of interventions used in the treatment/management of chronic fatigue syndrome and/or myalgic encephalomyelitis in adults and children

The effectiveness of interventions used in the treatment/management of chronic fatigue syndrome and/or myalgic encephalomyelitis in adults and children The effectiveness of interventions used in the treatment/management of chronic fatigue syndrome and/or myalgic encephalomyelitis in adults and children The effectiveness of interventions used in the treatment/management of chronic fatigue syndrome and/or myalgic encephalomyelitis in adults and children NHS Centre for Reviews and Dissemination (...) Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation NHS Centre for Reviews and Dissemination. The effectiveness of interventions used in the treatment/management of chronic fatigue syndrome and/or myalgic encephalomyelitis in adults and children. University of York. CRD Report 22. 2002 Authors' objectives The aim of this study was to assess

2002 Health Technology Assessment (HTA) Database.

210. Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction

Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction Ko D T, Hebert P R, Coffey C S, Sedrakyan A, Curtis J P, Krumholz H M Authors' objectives To determine the association of beta-blockers with depressive symptoms, fatigue and sexual dysfunction by performing a quantitative review of randomised trials (...) and had a diagnosis of myocardial infarction, hypertension or congestive heart failure. Outcomes assessed in the review The outcomes to be assessed were the frequency of depressive symptoms, fatigue or sexual dysfunction. The withdrawal of medication for depressive symptoms, fatigue or sexual dysfunction was also assessed. How were decisions on the relevance of primary studies made? The authors do not state how the papers were selected for the review, or how many of the reviewers performed

2002 DARE.

211. Systematic review of the current literature related to disability and chronic fatigue syndrome

Systematic review of the current literature related to disability and chronic fatigue syndrome Systematic review of the current literature related to disability and chronic fatigue syndrome Systematic review of the current literature related to disability and chronic fatigue syndrome Ganz N, Frame D, Estok R, Stone L, Ludensky V Authors' objectives The overall review objective was to assess how best to measure, monitor and treat disability in patients with chronic fatigue syndrome (CFS (...) , contract number 290-97-0016. Bibliographic details Ganz N, Frame D, Estok R, Stone L, Ludensky V. Systematic review of the current literature related to disability and chronic fatigue syndrome. Rockville, MD, USA: Agency for Healthcare Research and Quality. Evidence Report/Technology Assessment; 66. 2002 Original Paper URL Other publications of related interest Ross SD, Estok RP, Frame D, Stone LR, Ludensky V, Levine CB. Disability and chronic fatigue syndrome: a focus on function. Arch Intern Med

2002 DARE.

212. Management of cancer symptoms: pain, depression, and fatigue

Management of cancer symptoms: pain, depression, and fatigue Management of cancer symptoms: pain, depression, and fatigue Management of cancer symptoms: pain, depression, and fatigue Carr D, Goudas L, Lawrence D, Pirl W, Lau J, DeVine D, Kupelnick B, Miller K Authors' objectives The objective was to determine the prevalence, method of assessment and the effectiveness of treatment for cancer-related pain, depression and fatigue in patients with cancer. This abstract will focus only (...) pharmacological and non-pharmacological cytotoxic or cytostatic therapy. 4. To determine the relative efficacy of current adjuvant physical or psychological treatments. 5. To determine the relative efficacy of current invasive surgical and nonsurgical treatments. 6. To evaluate the effectiveness of treatments for cancer-related pain associated with oral mucositis post-herpetic neuralgia. Searching Separate searches were performed for each area: cancer-related pain, depression and fatigue. For cancer-related

2002 DARE.

213. Systematic review and meta-analysis of interventions for postoperative fatigue

Systematic review and meta-analysis of interventions for postoperative fatigue Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2002 DARE.

214. Fatigue in cancer patients during and after treatment: prevalence, correlates and interventions

Fatigue in cancer patients during and after treatment: prevalence, correlates and interventions Fatigue in cancer patients during and after treatment: prevalence, correlates and interventions Fatigue in cancer patients during and after treatment: prevalence, correlates and interventions Servaes P, Verhagen C, Bleijenberg G Authors' objectives To review the literature concerning interventions to reduce fatigue in cancer patients. Searching MEDLINE, Current Contents and PsycLIT were searched from (...) 1980 to July 2001. The search terms combined the words 'cancer' (or 'Hodgkin's' or 'tumor' or 'tumour' or 'malign*' or 'haematolog*') and ('intervention' or 'exercise' or 'psychotherapy' or 'group' or 'counsel*') in the title and the word 'fatigue' in the title, keyword or abstract. Only studies published in English or Dutch were included. Study selection Study designs of evaluations included in the review Controlled intervention studies of adult cancer patients, with a sample size of 15 or greater

2002 DARE.

215. Predictions and associations of fatigue syndromes and mood disorders that occur after infectious mononucleosis. (Abstract)

Predictions and associations of fatigue syndromes and mood disorders that occur after infectious mononucleosis. Certain infections can trigger chronic fatigue syndromes (CFS) in a minority of people infected, but the reason is unknown. We describe some factors that predict or are associated with prolonged fatigue after infectious mononucleosis and contrast these factors with those that predicted mood disorders after the same infection.We prospectively studied a cohort of 250 primary-care (...) patients with infectious mononucleosis or ordinary upper-respiratory-tract infections until 6 months after clinical onset. We sought predictors of both acute and chronic fatigue syndromes and mood disorders from clinical, laboratory, and psychosocial measures.An empirically defined fatigue syndrome 6 months after onset, which excluded comorbid psychiatric disorders, was most reliably predicted by a positive Monospot test at onset (odds ratio 2.1 [95% CI 1.4-3.3]) and lower physical fitness (0.35 [0.15

2001 Lancet

216. Randomised controlled trial of patient education to encourage graded exercise in chronic fatigue syndrome. Full Text available with Trip Pro

Randomised controlled trial of patient education to encourage graded exercise in chronic fatigue syndrome. To assess the efficacy of an educational intervention explaining symptoms to encourage graded exercise in patients with chronic fatigue syndrome.Randomised controlled trial.Chronic fatigue clinic and infectious diseases outpatient clinic.148 consecutively referred patients fulfilling Oxford criteria for chronic fatigue syndrome.Patients randomised to the control group received standardised (...) medical care. Patients randomised to intervention received two individual treatment sessions and two telephone follow up calls, supported by a comprehensive educational pack, describing the role of disrupted physiological regulation in fatigue symptoms and encouraging home based graded exercise. The minimum intervention group had no further treatment, but the telephone intervention group received an additional seven follow up calls and the maximum intervention group an additional seven face to face

2001 BMJ Controlled trial quality: uncertain

217. Fludrocortisone acetate to treat neurally mediated hypotension in chronic fatigue syndrome: a randomized controlled trial. (Abstract)

Fludrocortisone acetate to treat neurally mediated hypotension in chronic fatigue syndrome: a randomized controlled trial. Patients with chronic fatigue syndrome (CFS) are more likely than healthy persons to develop neurally mediated hypotension (NMH) in response to prolonged orthostatic stress.To examine the efficacy of fludrocortisone acetate as monotherapy for adults with both CFS and NMH.Randomized, double-blind, placebo-controlled trial conducted between March 1996 and February 1999.Two

2001 JAMA Controlled trial quality: predicted high

218. Cognitive behaviour therapy for chronic fatigue syndrome: a multicentre randomised controlled trial. (Abstract)

Cognitive behaviour therapy for chronic fatigue syndrome: a multicentre randomised controlled trial. Cognitive behaviour therapy (CBT) seems a promising treatment for chronic fatigue syndrome (CFS), but the applicability of this treatment outside specialised settings has been questioned. We compared CBT with guided support groups and the natural course in a randomised trial at three centres.Of 476 patients diagnosed with CFS, 278 were eligible and willing to take part. 93 were randomly assigned (...) CBT (administered by 13 therapists recently trained in this technique for CFS), 94 were assigned the support-group approach, and 91 the control natural course. Multidimensional assessments were done at baseline, 8 months, and 14 months. The primary outcome variables were fatigue severity (on the checklist individual strength) and functional impairment (on the sickness impact profile) at 8 and 14 months. Data were analysed by intention to treat.241 patients had complete data (83 CBT, 80 support

2001 Lancet Controlled trial quality: predicted high

219. Chronic fatigue syndrome

Chronic fatigue syndrome Chronic fatigue syndrome Chronic fatigue syndrome Dolors Estrada M Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Dolors Estrada M. Chronic fatigue syndrome. Barcelona: Catalan Agency for Health Information, Assessment and Quality (CAHIAQ -formerly CAHTA). IN01/2001. 2001 Authors' objectives To assess (...) the available evidence on the effectiveness of treatments for chronic fatigue syndrome (CFS). Authors' conclusions Based on evidence from randomised controlled trials, only cognitive behavioural therapy has been shown to benefit (improve) physical function in adults with CFS in ambulatory regimen, and on an individualised basis when compared to routine medical treatment. The lack of studies or the contradictory results in other treatments considered (antiviral, immunological, active agents on the central

2001 Health Technology Assessment (HTA) Database.

220. Defining and managing chronic fatigue syndrome

Defining and managing chronic fatigue syndrome Defining and managing chronic fatigue syndrome Defining and managing chronic fatigue syndrome Agency for Healthcare Research and Quality Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Agency for Healthcare Research and Quality. Defining and managing chronic fatigue syndrome. Rockville (...) : Agency for Healthcare Research and Quality (AHRQ). Evidence Report/Technology Assessment No. 42. 2001 Authors' objectives Objectives of this evidence report are to summarize research evidence regarding the case definitions, prevalence, natural history and therapy of chronic fatigue syndrome (CFS). Authors' conclusions Existing case definitions for CFS appear to characterize a group of people with prolonged fatigue and impaired ability to function. The validity and superiority of any particular case

2001 Health Technology Assessment (HTA) Database.