Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4)
Latest & greatest articles for folic acid
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on folic acid or other clinical topics then use Trip today.
This page lists the very latest high quality evidence on folic acid and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.
What is Trip?
Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.
Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.
As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.
For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via email@example.com
Reduction of plasma homocyst(e)ine levels by breakfast cereal fortified with folicacid in patients with coronary heart disease. The Food and Drug Administration (FDA) has recommended that cereal-grain products be fortified with folicacid to prevent congenital neural-tube defects. Since folicacid supplementation reduces levels of plasma homocyst(e)ine, or plasma total homocysteine, which are frequently elevated in arterial occlusive disease, we hypothesized that folicacid fortification might (...) reduce plasma homocyst(e)ine levels.To test this hypothesis, we assessed the effects of breakfast cereals fortified with three levels of folicacid, and also containing the recommended dietary allowances of vitamins B6 and B12, in a randomized, double-blind, placebo-controlled, crossover trial in 75 men and women with coronary artery disease.Plasma folicacid increased and plasma homocyst(e)ine decreased proportionately with the folicacid content of the breakfast cereal. Cereal providing 127 microg
Lowering blood homocysteine with folicacid-based supplements: meta-analysis of randomised trials Lowering blood homocysteine with folicacid-based supplements: meta-analysis of randomised trials Lowering blood homocysteine with folicacid-based supplements: meta-analysis of randomised trials Homocysteine Lowering Trialists' Collaboration Authors' objectives To determine the size of reduction in homocysteine concentrations produced by dietary supplementation with folicacid and with vitamins (...) B12 or B6. Searching English and non-English language studies were sought in MEDLINE. The reference lists were scanned and personal contact was made with relevant investigators. Study selection Study designs of evaluations included in the review Published and unpublished randomised controlled trials (RCTs) were included if they had assessed the effects on blood homocysteine concentrations of folicacid supplements with or without the addition of vitamins B6 or B12. Excluded were studies which did
Minimum effective dose of folicacid for food fortification to prevent neural-tube defects. Although a daily supplement of 400 micrograms folicacid has been shown to prevent neural-tube defects (NTD), most women do not take the recommended supplement. Thus, food fortification is to be introduced in the USA and is being considered in the UK. Because of safety concerns, the USA has chosen a level of fortification that will increase the average woman's intake by only 100 micrograms (...) . Such an increase, although safe, may be ineffective; but a trial to assess its efficacy would be unethical. Because women with red-cell folate concentrations above 400 micrograms/L have a very low risk of NTD, we undertook a randomised trial of several folicacid doses to find out how much is needed to reach this protective concentration.We screened 323 women. 172 with red-cell folate between 150 micrograms/L and 400 micrograms/L were invited to take part in the trial. 121 women were randomly assigned placebo
Folicacid fortification of grain: an economic analysis Folicacid fortification of grain: an economic analysis Folicacid fortification of grain: an economic analysis Romano P S, Waitzman N J, Scheffler R M, Pi R D Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study (...) and the conclusions drawn. Health technology Fortification of grain with folicacid to prevent neural tube defects (spina bifida and anencephaly). Type of intervention Primary prevention. Economic study type Cost-effectiveness analysis. Study population Women of child-bearing age (11 to 50 years). Setting Community. The economic study was carried out in California, USA. Dates to which data relate Data on the effectiveness of folicacid fortification was taken from two studies published in 1989 and 1991. The data