Latest & greatest articles for geriatrics

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on geriatrics or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on geriatrics and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for geriatrics

1. Managing Frailty and Associated Comorbidities in Older Adults with Diabetes

and associated comorbidities in older adults with diabetes: Position Statement on behalf of the Association of British Clinical Diabetologists (ABCD) ALAN SINCLAIR, 1 ALISON GALLAGHER 2 1 Foundation for Diabetes Research in Older People (FDROP), Diabetes Frail Ltd, Luton, UK 2 University Hospitals Leicester NHS Trust, Leicester, UK This Position Statement on the management of frailty in diabetes mellitus represents a timely initiative by the Association of British Clinical Diabetologists (ABCD) to address (...) Managing Frailty and Associated Comorbidities in Older Adults with Diabetes Managing frailty and associated comorbidities in older adults with diabetes: Position Statement on behalf of the Association of British Clinical Diabetologists (ABCD) | ABCD (Diabetes Care) Ltd Search form Search Search You are here » » Managing frailty and associated comorbidities in older adults with diabetes: Position Statement on behalf of the Association of British Clinical Diabetologists (ABCD) Managing frailty

2021 Association of British Clinical Diabetologists

2. Long-Term (Up to 27 Years) Prospective, Randomized Study of Mobile-Bearing and Fixed-Bearing Total Knee Arthroplasties in Patients <60 Years of Age With Osteoarthritis

Long-Term (Up to 27 Years) Prospective, Randomized Study of Mobile-Bearing and Fixed-Bearing Total Knee Arthroplasties in Patients <60 Years of Age With Osteoarthritis Long-Term (Up to 27 Years) Prospective, Randomized Study of Mobile-Bearing and Fixed-Bearing Total Knee Arthroplasties in Patients - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily (...) , Republic of Korea. PMID: 33223412 DOI: Item in Clipboard Full-text links Cite Display options Display options Format Abstract Background: Our study determined long-term (up to 27 years) results of fixed-bearing vs mobile-bearing total knee arthroplasties (TKAs) in patients <60 years with osteoarthritis. Methods: This study included 291 patients (582 knees; mean age 58 ± 5 years), who received a mobile-bearing TKA in one knee and a fixed-bearing TKA in the other. The mean duration of follow-up was 26.3

2021 EvidenceUpdates

3. The effectiveness of reminiscence-based intervention on improving psychological well-being in cognitively intact older adults: A systematic review and meta-analysis

Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. 4 Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address: nurwux@nus.edu.sg. PMID: 33352435 DOI: Item in Clipboard Full-text links Cite Display options Display options Format Abstract Background: Aging is one of the most important public health issues. The World Health Organization (WHO) expects the number of older adults aged 65 (...) and above to triple from 2010 to 2050. A major challenge would be to consider how functional ability and quality of life could be enhanced in older age. Reminiscence-based interventions are widely reported as having positive effects on psychological outcomes among older adults with dementia, but its effects on cognitively intact older adults have not been clearly evaluated. Objectives: The aim of the current systematic review is to evaluate the existing evidence on the effects of reminiscence-based

2021 EvidenceUpdates

4. Distal Femur Replacement Versus Surgical Fixation for the Treatment of Geriatric Distal Femur Fractures: A Systematic Review

options. The purpose of this study was to compare patient outcomes after these treatment strategies. Data sources: PubMed, Embase, and Cochrane databases were searched for English language articles up to April 24, 2020, identifying 2129 papers. Study selection: Studies evaluating complications in elderly patients treated for distal femur fractures with either immediate DFR or SF were included. Studies with mean patient age <55 years, nontraumatic indications for DFR, or SF with nonlocking plates were (...) Distal Femur Replacement Versus Surgical Fixation for the Treatment of Geriatric Distal Femur Fractures: A Systematic Review Distal Femur Replacement Versus Surgical Fixation for the Treatment of Geriatric Distal Femur Fractures: A Systematic Review - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly

2021 EvidenceUpdates

5. Abdominal aorta aneurysm (AAA) screening of men aged 65

Abdominal aorta aneurysm (AAA) screening of men aged 65 Abdominal aorta aneurysm (AAA) screening of men aged 65 - NIPH Search for: Søk Menu To top level Close Infectious diseases & Vaccines Mental & Physical health Environment & Lifestyle Health in Norway Quality & Knowledge Research & Access to data About NIPH Close Abdominal aorta aneurysm (AAA) screening of men aged 65 Order Download: Key message Abdominal aortic aneurysm (AAA) is a weakening of the aortic wall resulting in an abnormal (...) dilatation of the abdominal aortic artery. AAAs bears the risk of rupture, which is a dramatic emergency condition with a high risk of death. In Norway, about 1% of all deaths among men older than 65 years are caused by AAA rupture. The mortality rate due to AAA rupture is approximately 75%, with about half of the deaths occurring before the patient reaches the hospital. The larger the AAA, the higher is the risk of rupture. Prevalence of AAA among men varies across countries from approx. 1.5-3

2021 Norwegian Institute of Public Health

6. Melatonin (Slenyto) - Treatment of insomnia in children and adolescents aged 2 to 18 years with autism spectrum disorder and / or Smith-Magenis syndrome

at the melatonin receptors (MT1, MT2 and MT3) is believed to contribute to its sleep-promoting properties, as these receptors (mainly MT1 and MT2) are involved in the regulation of circadian rhythms and sleep regulation. 1 A double-blind phase III study recruited children and young people aged 2 to 17.5 years with an autism spectrum disorder diagnosed by the International Classification of Diseases 10 th revision (ICD-10), Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) or DSM-4 criteria (...) Melatonin (Slenyto) - Treatment of insomnia in children and adolescents aged 2 to 18 years with autism spectrum disorder and / or Smith-Magenis syndrome 1 Published 18 January 2021 1 SMC2306 melatonin 1mg and 5mg prolonged-release tablets (Slenyto®) Flynn Pharma Ltd 4 December 2020 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and Area Drug and Therapeutic Committees (ADTCs) on its use in NHS Scotland. The advice is summarised

2021 Scottish Medicines Consortium

7. The covid-19 messenger RNA vaccine tozinameran (Comirnaty, from Pfizer and BioNTech) in elderly patients: limited data, many uncertainties

increases with age. Vaccines are generally less immunogenic in older adults than in young adults, which may make vaccination less effective in elderly patients (5). The vaccine did not appear any less effective in preventing covid-19 (all severities combined) from day 7 after the second injection in vaccinees aged 55 years or older than in the younger vaccinees. Its calculated efficacy in vaccinees aged between 65 and 74 years was about 93%, but with a greater margin of uncertainty (95CI: 53% to 100 (...) also contain polyethylene glycol (PEG) 2000 (3). This vaccine contains no adjuvants or preservatives. In the short term, marked reduction in the number of cases of symptomatic, laboratory-confirmed covid-19 in one clinical trial. The clinical evaluation data available on the tozinameran vaccine as of December 2020 centre on a randomised trial in which the participants, aged 16 years or older, received two injections, 21 days apart, of either the vaccine or placebo. 42% of recipients were over 55

2021 Prescrire

8. Non-benzodiazepine hypnotic use for sleep disturbance in people aged over 55 years living with dementia: a series of cohort studies Full Text available with Trip Pro

Non-benzodiazepine hypnotic use for sleep disturbance in people aged over 55 years living with dementia: a series of cohort studies Non-benzodiazepine hypnotic use for sleep disturbance in people aged over 55 years living with dementia: a series of cohort studies Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try (...) a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} Z-drugs may increase fracture risk in people with dementia, but future research is needed to confirm these findings and to explore sleep management strategies for people with dementia. {{author}} {{($index , , , , , , , , , , & . Kathryn Richardson 1 , George M Savva 1, 2 , Penelope J Boyd 1, 3 , Clare Aldus 1 , Ian Maidment 4 , Eduwin Pakpahan 5

2021 NIHR HTA programme

9. COVID-19 vaccination: women of childbearing age, currently pregnant or breastfeeding

COVID-19 vaccination: women of childbearing age, currently pregnant or breastfeeding COVID-19 vaccination: women of childbearing age, currently pregnant, planning a pregnancy or breastfeeding - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Show or hide search Search on GOV.UK Search Menu (...) Guidance and support Take action now for new rules in 2021 Guidance COVID-19 vaccination: women of childbearing age, currently pregnant, planning a pregnancy or breastfeeding Information for all women of childbearing age, those currently pregnant, planning a pregnancy or breastfeeding on coronavirus (COVID-19) vaccination. Published 6 December 2020 From: Documents HTML Ref: PHE gateway number 2020374 PDF , 167KB , 2 pages This file may not be suitable for users of assistive technology. Request

2021 Public Health England

10. Lonafarnib (Zokinvy) - premature aging

Lonafarnib (Zokinvy) - premature aging Drug Approval Package: ZOKINVY U.S. Department of Health and Human Services Search FDA Submit search Drug Approval Package: ZOKINVY Company: Eiger BioPharmaceuticals, Inc. Application Number: 213969 Approval Date: 11/20/2020 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. FDA Approval Letter and Labeling (PDF) (PDF) FDA Application Review Files (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) Date (...) created: December 18, 2020 Vision impaired people having problems accessing certain pages of a PDF file may call (301) 796-3634 for assistance. Note: Documents in PDF format require the . Note: If you need help accessing information in different file formats, see . Language Assistance Available: | | | | | | | | | | | | | | | FDA Popular Content Product Areas

2021 FDA - Drug Approval Package

11. Improving outcomes for older people in the emergency department: a review of reviews Full Text available with Trip Pro

Improving outcomes for older people in the emergency department: a review of reviews Improving outcomes for older people in the emergency department: a review of reviews - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health information from CDC: Get (...) at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Review Emerg Med J Actions . 2020 Oct 26;emermed-2020-209514. doi: 10.1136/emermed-2020-209514. Online ahead of print. Improving outcomes for older people

2021 EvidenceUpdates

12. Cardiovascular outcomes and safety with linagliptin, a dipeptidyl peptidase-4 inhibitor, compared with the sulphonylurea glimepiride in older people with type 2 diabetes: A subgroup analysis of the randomized CAROLINA trial Full Text available with Trip Pro

with linagliptin, a dipeptidyl peptidase-4 inhibitor, compared with the sulphonylurea glimepiride in older people with type 2 diabetes: A subgroup analysis of the randomized CAROLINA trial Mark A Espeland et al. Diabetes Obes Metab . 2021 Feb . Show details Display options Display options Format Diabetes Obes Metab Actions . 2021 Feb;23(2):569-580. doi: 10.1111/dom.14254. Epub 2020 Dec 6. Authors , , , , , , , , , , , , Affiliations 1 Division of Gerontology and Geriatric Medicine, Wake Forest School (...) the cardiovascular (CV) safety of linagliptin with glimepiride in older and younger participants in the CAROLINA trial in both prespecified and post hoc analyses. Materials and methods: People aged 40 to 85 years with relatively early type 2 diabetes, inadequate glycaemic control and elevated CV risk were randomly assigned to linagliptin 5 mg or glimepiride 1 to 4 mg. The primary endpoint was time to first occurrence of three-point major adverse CV events (MACE: CV death, non-fatal myocardial infarction, or non

2021 EvidenceUpdates

13. Effects of a simple reminiscence intervention program on the reminiscence functions in older adults

Sep 6;54(2):515-23. doi: 10.3233/JAD-160497. J Alzheimers Dis. 2016. PMID: 27567866 O'Rourke N, Cappeliez P, Claxton A. O'Rourke N, et al. Aging Ment Health. 2011 Mar;15(2):272-81. doi: 10.1080/13607861003713281. Epub 2010 Dec 6. Aging Ment Health. 2011. PMID: 21140308 Bohlmeijer ET, Steunenberg B, Westerhof GJ. Bohlmeijer ET, et al. Tijdschr Gerontol Geriatr. 2011 Feb;42(1):7-16. doi: 10.1007/s12439-011-0002-9. Tijdschr Gerontol Geriatr. 2011. PMID: 21400958 Review. Dutch. Yen HY, Lin LJ. Yen HY (...) Effects of a simple reminiscence intervention program on the reminiscence functions in older adults Effects of a simple reminiscence intervention program on the reminiscence functions in older adults - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health

2021 EvidenceUpdates

14. Supporting wellbeing of older people when shielding/isolating

able to pay their telephone/broadband bills. Telephone communication providers should consider whether they are able to cap call and internet charges and provide unlimited use for elderly people during this period. What the evidence says We based these suggestions on the following research findings On quality of life older people report value in: ? Being able to manage on their own retaining dignity and not feeling like a burden ? Spending time doing activities that bring a sense of value, joy (...) comfortable and independent 2 This review looked at qualitative research, in people aged 65 or over who were still living independently, that investigated their views about occupations that enhanced their wellbeing. Authors found that: Solitary occupations are described as positive and highly important to older people’s wellbeing. ? Older people described the need for autonomy in deciding what to do and when to do it; occupations needed to be of their own choice ? They accepted the need for help

2020 Public Health Wales Observatory Evidence Service

15. COVID-19: Managing the COVID-19 pandemic in care homes for older people

COVID-19: Managing the COVID-19 pandemic in care homes for older people COVID-19: Managing the COVID-19 pandemic in care homes | British Geriatrics Society Toggle main menu visibility Search Search Search COVID-19: Managing the COVID-19 pandemic in care homes tool to recognise deterioration in residents, measure vital signs and communicate concerns to healthcare professionals. Care homes should have standard operating procedures for isolating residents who ‘walk with purpose’ (often referred (...) 2013;:afs174-. . Public Health England. COVID: Guidance for Health Professionals: . . . . . . Public Health England. COVID: Hospital Service Discharge Requirements: . . . NICE Guidance on ICU admission for people with COVID: Acknowledgements With very many thanks to the expert author group who assembled this guidance with the British Geriatrics Society: Prof Adam Gordon Professor of Care of Older People, University of Nottingham; Consultant Geriatrician, University Hospitals of Derby and Burton NHS

2020 British Geriatrics Society

16. Cognitive Impairment in Older Adults: Screening

population: prevalence and associated factors: results of the LIFE-Adult-Study. BMC Psychol . 2018;6:23. 19. Ginó S, Mendes T, Maroco J, et al. Memory complaints are frequent but qualitatively different in young and elderly healthy people. Gerontology . 2010;56(3):272-277. 20. Stites SD, Karlawish J, Harkins K, Rubright JD, Wolk D. Awareness of mild cognitive impairment and mild Alzheimer"s disease dementia diagnoses associated with lower self-ratings of quality of life in older adults. J Gerontol B (...) in the DSM-5 are complex attention, executive function, learning and memory, language, perceptual motor function, and social cognition. Dementia affects an estimated 2.4 to 5.5 million persons in the United States, and its prevalence increases with age. Dementia affects an estimated 3.2% of persons aged 65 to 74 years, 9.9% of those aged 75 to 84 years, and 29.3% of those 85 years or older. Mild cognitive impairment (MCI) differs from dementia in that the impairment is not severe enough to interfere

2020 U.S. Preventive Services Task Force

17. Activities of daily living at hospital admission and estimated survival time of older patients

Department, Holbæk Hospital, Holbæk, Denmark. 6 Department of Geriatric Medicine, Aalborg University Hospital, Aalborg, Denmark. 7 Medical Department, Kolding Hospital, Kolding, Denmark. 8 Medical Department, Odense University Hospital, Svendborg, Denmark. 9 Department of Geriatric Medicine, Nottingham University Hospital, Nottingham, UK. PMID: 33247584 DOI: Item in Clipboard Activities of daily living at hospital admission and estimated survival time of older patients Jesper Ryg et al. Age Ageing . 2020 (...) options Format Abstract Background: Predicting expected survival time in acutely hospitalised older patients is a clinical challenge. Objective: To examine if activities of daily living (ADL) assessed by Barthel-Index-100 (Barthel-Index) at hospital admission adds useful information to clinicians on expected survival time in older patients. Methods: A nationwide population-based cohort study was used. All patients aged ≥65 years in the National Danish Geriatric Database from 2005 to 2014 were followed

2020 EvidenceUpdates

18. Vitamin C to Pregnant Smokers Persistently Improves Infant Airway Function to 12 Months of Age: A Randomised Trial

Vitamin C to Pregnant Smokers Persistently Improves Infant Airway Function to 12 Months of Age: A Randomised Trial Vitamin C to Pregnant Smokers Persistently Improves Infant Airway Function to 12 Months of Age: A Randomised Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation (...) to Pregnant Smokers Persistently Improves Infant Airway Function to 12 Months of Age: A Randomised Trial , , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA mcevoyc@ohsu.edu. 2 Division of Neuroscience, Oregon National Primate Research Center, Beaverton, OR, USA. 3 Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA. 4 Department of Pediatrics, Indiana University School of Medicine

2020 EvidenceUpdates

19. Evaluation of Time to Benefit of Statins for the Primary Prevention of Cardiovascular Events in Adults Aged 50 to 75 Years: A Meta-analysis

: 10.1001/jamainternmed.2020.6084. Online ahead of print. Evaluation of Time to Benefit of Statins for the Primary Prevention of Cardiovascular Events in Adults Aged 50 to 75 Years: A Meta-analysis , , , , , , , , , , Affiliations Expand Affiliations 1 Division of Geriatrics and Gerontology, School of Medicine, University of California, San Diego. 2 Geriatrics, Palliative and Extended Care Service Line, San Francisco VA (Veterans Affairs) Health Care System, San Francisco, California. 3 Division (...) and Education, San Francisco. 5 Department of Medicine, Harvard Medical School, Cambridge, Massachusetts. 6 Department of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts. 7 Division of Geriatric Medicine and Gerontology, School of Medicine, John Hopkins University, Baltimore, Maryland. 8 New England GRECC (Geriatrics Research, Education and Clinical Center), VA Boston Healthcare System, Boston, Massachusetts. 9 Division of Aging, Brigham & Women's Hospital

2020 EvidenceUpdates

20. Gabapentin to reduce pain in women aged between 18 and 50 years with chronic pelvic pain: the GaPP2 RCT Full Text available with Trip Pro

Gabapentin to reduce pain in women aged between 18 and 50 years with chronic pelvic pain: the GaPP2 RCT Gabapentin to reduce pain in women aged between 18 and 50 years with chronic pelvic pain: the GaPP2 RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you need

2020 NIHR HTA programme