Latest & greatest articles for geriatrics

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Top results for geriatrics

81. Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial

Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features (...) a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation J Clin Oncol Actions , 38 (3), 248-256 2020 Jan 20 Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial , , , , , , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 University Medical Center Groningen

2020 EvidenceUpdates

82. Developing an all-age response to meet the age-specific needs of service users

Developing an all-age response to meet the age-specific needs of service users NHS England » Developing an all-age response to meet the age-specific needs of service users Search Search Menu Developing an all-age response to meet the age-specific needs of service users Document first published: 22 January 2020 Page updated: 22 January 2020 Topic: Publication type: Document PDF 476 KB 14 pages

2020 NHS England

83. Incident psychiatric comorbidity following stress disorder diagnoses in Danish school-aged children: prospective population-based study

Incident psychiatric comorbidity following stress disorder diagnoses in Danish school-aged children: prospective population-based study Incident Psychiatric Comorbidity Following Stress Disorder Diagnoses in Danish School-Aged Children: Prospective Population-Based Study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other (...) characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Br J Psychiatry Actions , 1-6 2019 Nov 22 [Online ahead of print] Incident Psychiatric Comorbidity Following Stress Disorder Diagnoses in Danish School-Aged Children: Prospective Population-Based Study , , , , , , Affiliations Expand Affiliations 1 Research Associate

2020 EvidenceUpdates

84. Physical Activity: Digital Health Interventions for Adults 55 Years and Older

Studies The number of studies and publications do not always correspond (e.g., a publication may include several studies or one study may be explained in several publications). . Bickmore TW, Silliman RA, Nelson K, Cheng DM, Winter M, et al.. A randomized controlled trial of an automated exercise coach for older adults. J Am Geriatr Soc 2013;61:1676–83. Freene N. Physiotherapist-led home-based physical activity program versus community group exercise for middle-aged adults: quasi-experimental (...) , Castro CM, et al. Promoting physical activity through hand-held computer technology. Am J Prev Med 2008;34:138–42. King AC, Bickmore TW, Campero MI, Pruitt LA, Yin JL. Employing virtual advisors in preventive care for underserved communities: results from the COMPASS study. J Health Commun 2013b;18:1449–64. Kolt GS, Schofield GM, Kerse N, Garrett N, Oliver M. Effect of telephone counseling on physical activity for low-active older people in primary care: a randomized, controlled trial. J Am Geriatr

2020 Community Preventive Services Task Force

85. Valproate and Retinoic Acid in Combination With Decitabine in Elderly Nonfit Patients With Acute Myeloid Leukemia: Results of a Multicenter, Randomized, 2 x 2, Phase II Trial (Abstract)

inhibitor valproate and all-trans retinoic acid (ATRA) in treatment-naive elderly patients with acute myeloid leukemia (AML).Two hundred patients (median age, 76 years; range, 61-92 years) ineligible for induction chemotherapy received decitabine (20 mg/m2 intravenously, days 1 to 5) alone (n = 47) or in combination with valproate (n = 57), ATRA (n = 46), or valproate + ATRA (n = 50). The primary endpoint was objective response, defined as complete and partial remission, tested at a one-sided (...) Valproate and Retinoic Acid in Combination With Decitabine in Elderly Nonfit Patients With Acute Myeloid Leukemia: Results of a Multicenter, Randomized, 2 x 2, Phase II Trial DNA-hypomethylating agents are studied in combination with other epigenetic drugs, such as histone deacetylase inhibitors or differentiation inducers (eg, retinoids), in myeloid neoplasias. A randomized, phase II trial with a 2 × 2 factorial design was conducted to investigate the effects of the histone deacetylase

2020 EvidenceUpdates

86. The CHIRPY DRAGON intervention in preventing obesity in Chinese primary-school--aged children: A cluster-randomised controlled trial Full Text available with Trip Pro

The CHIRPY DRAGON intervention in preventing obesity in Chinese primary-school--aged children: A cluster-randomised controlled trial The CHIRPY DRAGON Intervention in Preventing Obesity in Chinese Primary-School--Aged Children: A Cluster-Randomised Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced (...) characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Randomized Controlled Trial PLoS Med Actions , 16 (11), e1002971 2019 Nov 26 eCollection Nov 2019 The CHIRPY DRAGON Intervention in Preventing Obesity in Chinese Primary-School--Aged Children: A Cluster-Randomised Controlled Trial , , , , , , , , , , , Affiliations Expand

2020 EvidenceUpdates

87. Examining the relationship between triage acuity and frailty to inform the care of older emergency department patients: Findings from a large Canadian multisite cohort study (Abstract)

Examining the relationship between triage acuity and frailty to inform the care of older emergency department patients: Findings from a large Canadian multisite cohort study The 2016 Canadian Triage and Acuity Scale (CTAS) updates introduced frailty screening within triage to more accurately code frail patients who may deteriorate waiting for care. The relationship between triage acuity and frailty is not well understood, but may help inform which supplemental geriatric assessments (...) are beneficial to support care in the emergency department (ED). Our objectives were to investigate the relationship between triage acuity and frailty, and to compare their associations with a series of patient outcomes.We conducted a secondary analysis of the Canadian cohort from a multinational prospective study. Data were collected on ED patients 75 years of age and older from eight ED sites across Canada between November 2009 and April 2012. Triage acuity was assigned using the CTAS, whereas frailty

2020 EvidenceUpdates

88. Testosterone Treatment in Adult Men With Age-Related Low Testosterone: A Clinical Guideline From the American College of Physicians. (Abstract)

Testosterone Treatment in Adult Men With Age-Related Low Testosterone: A Clinical Guideline From the American College of Physicians. The American College of Physicians (ACP) developed this guideline to provide clinical recommendations based on the current evidence of the benefits and harms of testosterone treatment in adult men with age-related low testosterone. This guideline is endorsed by the American Academy of Family Physicians.The ACP Clinical Guidelines Committee based (...) these recommendations on a systematic review on the efficacy and safety of testosterone treatment in adult men with age-related low testosterone. Clinical outcomes were evaluated by using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) system and included sexual function, physical function, quality of life, energy and vitality, depression, cognition, serious adverse events, major adverse cardiovascular events, and other adverse events.The target audience includes all clinicians

2020 Annals of Internal Medicine

89. Effectiveness and Cost-Effectiveness of Human Papillomavirus Vaccination Through Age 45 Years in the United States. (Abstract)

effects from the current HPV vaccination program.The current HPV vaccination program is predicted to be cost saving. Extending vaccination to older ages is predicted to produce small additional health benefits and result in substantially higher incremental cost-effectiveness ratios than the current recommendation.Centers for Disease Control and Prevention. (...) Effectiveness and Cost-Effectiveness of Human Papillomavirus Vaccination Through Age 45 Years in the United States. In the United States, the routine age for human papillomavirus (HPV) vaccination is 11 to 12 years, with catch-up vaccination through age 26 years for women and 21 years for men. U.S. vaccination policy on use of the 9-valent HPV vaccine in adult women and men is being reviewed.To evaluate the added population-level effectiveness and cost-effectiveness of extending the current U.S

2020 Annals of Internal Medicine

90. Predicting 6-Month Mortality for Older Adults Hospitalized With Acute Myocardial Infarction: A Cohort Study. (Abstract)

study. (ClinicalTrials.gov: NCT01755052).94 hospitals throughout the United States.3006 persons aged 75 years or older who were hospitalized with AMI and discharged alive.Functional impairments were assessed during hospitalization via direct measurement (cognition, mobility, muscle strength) or self-report (vision, hearing). Clinical variables associated with mortality in prior risk models were ascertained by chart review. Seventy-two candidate variables were selected for inclusion, and backward (...) Predicting 6-Month Mortality for Older Adults Hospitalized With Acute Myocardial Infarction: A Cohort Study. Older adults with acute myocardial infarction (AMI) have higher prevalence of functional impairments, including deficits in cognition, strength, and sensory domains, than their younger counterparts.To develop and evaluate the prognostic utility of a risk model for 6-month post-AMI mortality in older adults that incorporates information about functional impairments.Prospective cohort

2020 Annals of Internal Medicine

91. Guidance for Providers Caring for Women and Men Of Reproductive Age with Possible Zika Virus Exposure

Guidance for Providers Caring for Women and Men Of Reproductive Age with Possible Zika Virus Exposure -1- Guidance for Providers Caring for Women and Men Of Reproductive Age with Possible Zika Virus Exposure (Modified from CDC a- i FDA j-l and WHO k Published Guidance) Updated July 2019 Planning Pregnancy for Infected, Exposed, or Possibly Exposed Individuals This is an update of the ASRM Zika virus guidance for providers that addresses the care of non-pregnant patients desiring pregnancy (...) taking into account any new available data and such variables as age of the female patient and other infertility factors with documentation of the conversation and decision. 4. Symptomatic women and men attempting pregnancy through ART with possible Zika virus exposure should have testing that includes the Zika virus nucleic acid test (NAT) to rule out active Zika infection, and serologic testing, as outlined in section #8 below, to identify Zika immunity, before proceeding on with infertility

2020 Society for Assisted Reproductive Technology

92. Best-practice prevention alone or with conventional or biological caries management for 3- to 7-year-olds: the FiCTION three-arm RCT

Best-practice prevention alone or with conventional or biological caries management for 3- to 7-year-olds: the FiCTION three-arm RCT Best-practice prevention alone or with conventional or biological caries management for 3- to 7-year-olds: the FiCTION three-arm RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try

2020 NIHR HTA programme

93. Combination non-pharmacologic intervention for orthostatic hypotension in older people: a phase 2 study Full Text available with Trip Pro

to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Age Ageing Actions 2019 Dec 23 [Online ahead of print] Combination Non-Pharmacologic Intervention for Orthostatic Hypotension in Older People: A Phase 2 Study , Affiliations Expand Affiliations 1 Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. 2 The Falls and Syncope Service, Newcastle upon Tyne (...) Hospitals NHS Foundation Trust, Newcastle upon Tyne NE1 4LP, UK. 3 NIHR Newcastle Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Trust and Newcastle University, Newcastle upon Tyne, UK. PMID: 31868889 DOI: Item in Clipboard Combination Non-Pharmacologic Intervention for Orthostatic Hypotension in Older People: A Phase 2 Study James Frith et al. Age Ageing . 2019 Show details Age Ageing Actions Authors , Affiliations 1 Institute of Cellular Medicine, Newcastle University, Newcastle upon

2020 EvidenceUpdates

94. Ageing and mobility: A grand challenge

as a barrier to use and improvement. This results in difficulties for individuals to navigate the systems and weakens system-wide incentives for integration and innovation. On average at least one-third of older people report unmet travel needs. It worsens with age, and women were reported to be more affected than men. (Luiu et al 2016). Mobility challenges faced in later life6 © Centre for Ageing Better 20197 © Centre for Ageing Better 2019 As we grow older, we are more likely to have health conditions (...) % of older people cannot reach a hospital within 30 minutes by public transport. (Future of Mobility: Evidence Review). Accessible and inclusive new technologies, services and business models Opportunities for innovation8 © Centre for Ageing Better 2019 Specific issues to address in their development include: - New vehicles, including Autonomous Vehicles, need to be designed to be accessible for people with limited mobility. - Addressing the door to vehicle portion of the journey, which can

2020 The Centre for Ageing Better

95. The State of Ageing in 2019: Adding life to our years

occupations. Pessimism about getting older is also linked to poorer health. People who worry about their health getting worse and those who expect to get lonely are around 30% more likely to have a negative experience of ageing than people who don’t. 31 8% 6% 5% 3% 3% 25 to 34 year olds 50 to 64 year olds 35 to 49 year olds 65 to 74 year olds 75 and over professional occupations routine occupations 7% 20% Later lives todayHow will future generations experience later life? In less than 20 years, the number (...) at risk. HealthHousing The majority of people continue to live in mainstream houses as they grow older, rather than moving into specialist accommodation, and increasing numbers of over 50s are renting. Yet UK housing stock is by and large unsuitable for people to grow old in.The State of Ageing in 2019 Adding life to our years 27 Housing With 38% of our homes dating from before 1946 (21% from before 1919), and just 7% from after 2000, the UK has the oldest housing stock in the EU. 69 Unsurprisingly

2020 The Centre for Ageing Better

96. Efficacy, safety, and tolerability of mirabegron in patients aged >/=65yr with overactive bladder wet: a phase IV, double-blind, randomised, placebo-controlled study (PILLAR)

. Safety and tolerability were consistent with the known mirabegron safety profile. Conclusions: Mirabegron efficacy, safety, and tolerability over 12 wk were confirmed in patients aged ≥65yr with OAB and incontinence. Patient summary: We examined the effect of mirabegron compared with placebo in people aged 65yr or older with overactive bladder and incontinence. Mirabegron improved the symptoms of overactive bladder compared with placebo. Side effects were similar to those already known for mirabegron (...) of Mirabegron in Patients Aged ≥65yr With Overactive Bladder Wet: A Phase IV, Double-Blind, Randomised, Placebo-Controlled Study (PILLAR) Adrian Wagg et al. Eur Urol . Feb 2020 Show details Eur Urol Actions , 77 (2), 211-220 Authors , , , , , Affiliations 1 Geriatric Medicine, University of Alberta, Edmonton, Alberta, Canada. Electronic address: adrian.wagg@ualberta.ca. 2 Division of Urology, St Elizabeth's Medical Center, Boston, MA, USA. 3 Bayview Research Group, LLC, Valley Village, CA, USA. 4 Sunnybrook

2020 EvidenceUpdates

97. State of Ageing 2019 infographics

and Chelsea Disability free life expectancy Total life expectancySource: +"CFMMBOE/"NJO4NJUIFUBM 5IF%ZOBNJDTPG"HF JOH &WJEFODFGSPNUIF&OHMJTI-POHJUVEJOBM4UVEZPG"HFJOH 8BWF 1 in 5 people aged 55-64 have a health problem that limits the kind of work they can doSource: +"CFMMBOE/"NJO4NJUIFUBM 5IF%ZOBNJDTPG"HF JOH &WJEFODFGSPNUIF&OHMJTI-POHJUVEJOBM4UVEZPG"HFJOH 8BWF More than a quarter of the poorest men aged 50 and over are smokers, compared to 5% of the wealthiest 27% 5% 5% 19% 1 oor FTURu J O UJMe 8 FB (...) &WJEFODFGSPNUIF&OHMJTI-POHJUVEJOBM4UVEZPG"HFJOH 8BWF Compared to the wealthiest quintile, the poorest quintile of men aged 50 and over are: 3x 2x 2x NPr FMJ L e M Z U o h B W e chronic heart disease N or FMJ L e M Z U o h B W e Type 2 diabetes N or FMJ L e M Z U o h BWe arthritis4PVSDF0tDFPG/BUJPOBM4UBUJTUJDT .FBTVSJOHOBUJPOBMXFMMCFJOH EPNBJOTBOENFBTVSFT CBTFE - POFMJOFTTB T FDUT QFPQMFP GBMMBHFT 8% 6% 5% 3% 3% 25 to 34 year olds 50 to 64 year olds 35 to 49 year olds 65 to 74 year olds 75 and over

2020 The Centre for Ageing Better

98. Measuring ageing: An introduction to the Ageing Better Measures Framework

Better 2019 Local monitoring and evaluation We are also making use of the ABMF at a local level. We are working with the Greater Manchester Combined Authority, Leeds City Council and Leeds Older People’s Forum, supporting them, as well as other members of the UK Network of Age-Friendly Communities, in their use of data and measures to understand local experiences of ageing and monitor progress. We look forward to continuing to work with these and other partners interested in measuring what matters (...) Measuring ageing: An introduction to the Ageing Better Measures Framework Measuring ageing: An introduction to the Ageing Better Measures Framework Centre for Ageing Better January 20193 © Centre for Ageing Better 2019 About the Centre for Ageing Better The Centre for Ageing Better is a charity, funded by an endowment from The National Lottery Community Fund, working to create a society where everyone enjoys a good later life. We want more people to be in fulfilling work, in good health, living

2020 The Centre for Ageing Better

99. Preventing respiratory illness in older adults aged 60 years and above living in long-term care

Preventing respiratory illness in older adults aged 60 years and above living in long-term care Preventing respiratory illness in older adults aged 60 years and above living in long-term care - CEBM CEBM The Centre for Evidence-Based Medicine develops, promotes and disseminates better evidence for healthcare. Navigate this website Preventing respiratory illness in older adults aged 60 years and above living in long-term care March 28, 2020 Patricia Rios, Amruta Radhakrishnan, Sonia M. Thomas (...) ) or mixed evidence of effectiveness (e.g., rimantadine, zanamivir, hand hygiene, personal protective equipment). The mixed evidence on hand hygiene and use of personal protective equipment does not imply these should not be used in outbreaks BACKGROUND The Infection Prevention & Control of the World Health Organization (WHO) Health Emergency Programme commissioned a review on preventing and managing COVID-19 in older adults aged 60 years and above living in long-term care facilities. The overall

2020 Oxford COVID-19 Evidence Service

100. Guidelines for preventing respiratory illness in older adults aged 60 years and above living in long-term care

Guidelines for preventing respiratory illness in older adults aged 60 years and above living in long-term care Guidelines for preventing respiratory illness in older adults aged 60 years and above living in long-term care - CEBM CEBM The Centre for Evidence-Based Medicine develops, promotes and disseminates better evidence for healthcare. Navigate this website Guidelines for preventing respiratory illness in older adults aged 60 years and above living in long-term care March 28, 2020 Patricia (...) , these recommendations should be viewed with caution as it is unclear how many of these guidelines are based on the best available evidence due to their poor overall quality. BACKGROUND The Infection Prevention & Control of the World Health Organization (WHO) Health Emergency Programme commissioned a review on preventing and managing COVID-19 in older adults aged 60 years and above living in long-term care facilities. The overall objective of this rapid review of clinical practice guidelines was to identify

2020 Oxford COVID-19 Evidence Service