Latest & greatest articles for gestational diabetes

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Top results for gestational diabetes

21. Gestational diabetes mellitus

Gestational diabetes mellitus Gestational diabetes mellitus - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Gestational diabetes mellitus Last reviewed: February 2019 Last updated: April 2018 Summary Develops during pregnancy and is usually diagnosed at 24 to 28 weeks of gestation on the basis of elevated plasma glucose levels on glucose tolerance testing. Goal of therapy is to achieve maternal glucose levels (...) that are as close to normal as possible in order to avoid fetal macrosomia and complications. Initial therapy for gestational diabetes is usually dietary modification. Insulin is started when acceptable glucose levels cannot be maintained with diet alone. Maternal postnatal testing for diabetes or impaired glucose tolerance is performed at least 6 weeks following delivery. The risk for recurrence of GDM in subsequent pregnancies or progression to type 2 diabetes is high. Definition Gestational diabetes mellitus

2018 BMJ Best Practice

22. Gestational diabetes mellitus — an update on screening, diagnosis, and follow-up

Gestational diabetes mellitus — an update on screening, diagnosis, and follow-up '); } else { document.write(' '); } ACE | Gestational diabetes mellitus — an update on screening, diagnosis, and follow-up Search > > Gestational diabetes mellitus — an update on screening, diagnosis, and follow-up - Gestational diabetes mellitus — an update on screening, diagnosis, and follow-up Published on 28 May 2018 This Appropriate Care Guide (ACG) features new recommendations for screening and diagnosing (...) gestational diabetes mellitus. It highlights the shift from risk-based to universal screening for all women at 24 to 28 weeks of gestation, and WHO 1999 to IADPSG 2010 glucose thresholds for GDM. It also highlights the importance of long-term care for women with GDM history. Download the PDF below to access the full ACG. Key Messages 1. During their first trimester, screen high-risk women for pre-existing diabetes using non-pregnancy glucose thresholds. If results are normal, re-evaluate women for GDM

2018 Appropriate Care Guides, Agency for Care Effectiveness (Singapore)

23. Comparison of umbilical artery Doppler and non-stress test in assessment of fetal well-being in gestational diabetes mellitus: A prospective cohort study Full Text available with Trip Pro

Comparison of umbilical artery Doppler and non-stress test in assessment of fetal well-being in gestational diabetes mellitus: A prospective cohort study Gestational diabetes mellitus (GDM) is one of the most common medical complications of pregnancy and is related to poor perinatal outcomes. Reduction of neonatal complications of GDM is feasible by assessment of fetal well-being. Both fetal Doppler and NST are used for the screening of high-risk pregnancies.We aimed to compare the non-stress (...) test (NST) and umbilical artery (UA) Doppler assessments for evaluation of the adverse perinatal outcomes in GDM.We conducted a prospective cohort study on 50 pregnant women with GDM in Jame Zanan Hospital, Tehran, Iran, from Oct 2014 to Sep 2015. A convenient sampling method was used for patient recruitment. Inclusion criteria were women with GDM, singleton pregnancies, and gestational age>32 weeks who had neither medical conditions nor fetal anomalies. Adverse perinatal outcomes were defined

2017 Electronic physician

24. miR-494 protects pancreatic β-cell function by targeting PTEN in gestational diabetes mellitus Full Text available with Trip Pro

miR-494 protects pancreatic β-cell function by targeting PTEN in gestational diabetes mellitus Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications characterized by insulin resistance and pancreatic β-cell dysfunction. Increasing evidence suggests that microRNAs (miRNAs) play key roles in the diverse types of diabetes, including GDM. However, the underlying mechanisms remain largely unknown. The purpose of this study is to investigate the role of microRNAs (...) in GDM. The microarray data of dysregulated miRNAs in blood and placenta was retrieved in the GEO dataset under the accession number GSE19649. Quantitative reverse transcription PCR (qRT-PCR) was performed to analyze the expression levels of miR-494 in peripheral blood from twenty pairs of gestational diabetes (GDM) women and healthy women. Then, we investigated the effects of miR-494 on the insulin secretion of pancreatic β-cells. Moreover, the role of this miR-494 in regulating the proliferation

2017 EXCLI journal

25. Health app: GDm-Health for people with gestational diabetes

Health app: GDm-Health for people with gestational diabetes Health app: GDm-Health for people with Health app: GDm-Health for people with gestational diabetes gestational diabetes Medtech innovation briefing Published: 13 November 2017 nice.org.uk/guidance/mib131 pathways Summary Summary About this app GDm-Health is a health application designed for people with gestational diabetes to allow for remote monitoring of blood glucose levels and communication with healthcare professionals. The mobile (...) a positive impact for people with gestational diabetes. There is some evidence that the app is a reliable method to communicate blood glucose levels and improves patient satisfaction with their care. However, there is currently no evidence comparing GDm-Health with standard care and so the impact on clinical outcomes is uncertain. Cost and resource impact Cost and resource impact: Cost savings may arise from reducing the need for face-to-face appointments but the overall resource impact has not been

2017 National Institute for Health and Clinical Excellence - Advice

26. microRNA-503 contribute to pancreatic beta cell dysfunction by targeting the mTOR pathway in gestational diabetes mellitus Full Text available with Trip Pro

microRNA-503 contribute to pancreatic beta cell dysfunction by targeting the mTOR pathway in gestational diabetes mellitus Loss of pancreatic β cells is involved in pathogenesis of gestational diabetes mellitus (GDM). Recently, several studies have elucidated the connection between microRNAs (miRNAs) and diabetes mellitus (DM), but the role of miRNAs in GDM remains unclear. The aim of this study was to evaluate the potential functions of miRNAs in GDM and to investigate the underlying

2017 EXCLI journal

27. Gestational diabetes mellitus: The prevalence, associated factors and foeto-maternal outcome of women attending antenatal care Full Text available with Trip Pro

Gestational diabetes mellitus: The prevalence, associated factors and foeto-maternal outcome of women attending antenatal care The aim of the study is to determine the prevalence of gestational diabetes mellitus (GDM), its associated risk factors, foeto-maternal outcomes and prevalence of postnatal diabetes mellitus (DM).This is a cross-sectional study using retrospective data from existing antenatal records of new antenatal women who registered at 72 public health clinics in Selangor (...) in January 2014.A total of 745 antenatal records were reviewed. The prevalence of GDM women was 27.9% (n = 184). GDM risks were higher in women aged 35 years old and above and in those with maternal obesity. GDM women had a higher risk of having a non-spontaneous vaginal delivery compared to non-GDM women. The prevalence of postnatal DM among GDM mother was 12.1%. Working GDM mothers were at higher risk of developing postnatal DM.The prevalence of GDM among newly registered women attending antenatal

2017 Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia

28. Interconception care for women with a history of gestational diabetes for improving maternal and infant outcomes. Full Text available with Trip Pro

Interconception care for women with a history of gestational diabetes for improving maternal and infant outcomes. Gestational diabetes mellitus (GDM) is associated with adverse health outcomes for mothers and their infants both perinatally and long term. Women with a history of GDM are at risk of recurrence in subsequent pregnancies and may benefit from intervention in the interconception period to improve maternal and infant health outcomes.To assess the effects of interconception care

2017 Cochrane

29. Gestational Diabetes Mellitus and Frequency of Blood Glucose Monitoring: A Randomized Controlled Trial (Abstract)

Gestational Diabetes Mellitus and Frequency of Blood Glucose Monitoring: A Randomized Controlled Trial To assess whether testing blood glucose four times daily compared with four times every other day would lead to similar birth weights among patients with gestational diabetes mellitus (GDM).This noninferiority randomized controlled trial was conducted at five centers. After receiving a diagnosis of GDM, women tested their blood glucose every day for 7 days. After that period, compliant women (...) were randomized, 149 (51%) were tested four times a day and 144 (49%) were tested every other day. Between the two groups, there were no significant differences with regard to need for medical treatment, induction, gestational age at delivery, mode of delivery, rate of preeclampsia, or shoulder dystocia. Birth weight was similar between both groups and the upper bound of the 90% confidence interval (CI) was less than 165 g, establishing noninferiority with a mean difference of -41 g (90% CI -137

2017 EvidenceUpdates

30. Sensitivity of postnatal fasting plasma glucose in identifying impaired glucose tolerance in women with gestational diabetes – 25 Years’ data Full Text available with Trip Pro

Sensitivity of postnatal fasting plasma glucose in identifying impaired glucose tolerance in women with gestational diabetes – 25 Years’ data To assess the uptake of postnatal oral glucose tolerance test and to determine the sensitivity of fasting postnatal blood sugar in predicting 2-h impaired glucose tolerance.Retrospective study of 1961 women diagnosed with gestational diabetes mellitus. All women were offered oral glucose tolerance test six weeks post-delivery.Of 1961 women, 1090 (56

2017 Obstetric medicine

31. Childhood maltreatment and inflammation among pregnant women with gestational diabetes mellitus: A pilot study Full Text available with Trip Pro

Childhood maltreatment and inflammation among pregnant women with gestational diabetes mellitus: A pilot study Women with childhood maltreatment histories are at increased risk for adverse birth outcomes. Mechanisms explaining this link are poorly understood. Past research is limited by sampling pregnant women at low risk for adverse maternal and neonatal outcomes.This pilot study was a secondary data analysis of 24 women with gestational diabetes mellitus; 17% of the sample also reported (...) in pregnant women diagnosed with gestational diabetes mellitus.

2017 Obstetric medicine

32. Periodontal Disease is a Risk Factor for the Development of Gestational Diabetes Mellitus

Periodontal Disease is a Risk Factor for the Development of Gestational Diabetes Mellitus UTCAT3223, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Periodontal Disease is a Risk Factor for the Development of Gestational Diabetes Mellitus Clinical Question In pregnant women, does having periodontal disease increase the risk of gestational diabetes mellitus (GDM)? Clinical Bottom Line Studies have shown that periodontal (...) disease and its inflammatory mediators are associated with an increased risk for the development of gestational diabetes. This is based on a meta-analysis of 5,724 pregnant patients including 624 cases of GDM. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Abariga/2016 Females with periodontal disease Meta-Analysis Key results Forty-four articles were reviewed, and 10 studies met the eligibility criteria

2017 UTHSCSA Dental School CAT Library

33. High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus Full Text available with Trip Pro

High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus Gestational diabetes mellitus (GDM), defined as any degree of glucose intolerance with first recognition during pregnancy, is a heterogeneous form of diabetes characterized by various degrees of β-cell dysfunction.We aimed to estimate the prevalence of possibly pathogenic variants in the maturity-onset diabetes of the young genes GCK, HNF1A, HNF4A, HNF1B, and INS among women (...) in anthropometric traits, high-sensitivity C-Reactive Protein (CRP), and glucose metabolism were measured.At baseline, 17 possibly disease-causing variants were found in 21 women, revealing a combined GCK, HNF1A, HNF4A, HNF1B, and INS variant prevalence of 5.9% (95% confidence interval: 3.5% to 8.4%). At follow-up, 15 out of 135 women with diabetes (11%) were carriers of variants in GCK, HNF1A, HNF4A, HNF1B, or INS.Almost 6% of Danish women with diet-treated GDM have possibly pathogenic variants in GCK, HNF1A

2017 Journal of the Endocrine Society

34. Correlation of the plasma sphingoid base profile with results from oral glucose tolerance tests in gestational diabetes mellitus Full Text available with Trip Pro

Correlation of the plasma sphingoid base profile with results from oral glucose tolerance tests in gestational diabetes mellitus Oral glucose tolerance test (OGTT) is usually insufficient to accurately predict the risk for type 2 diabetes mellitus (T2DM), it is therefore necessary to identify an additional biomarker that would most likely improve the accuracy of OGTT. The current OGTT was performed in 53 volunteers after ingestion of 75 g glucose in 250 ml water to each volunteer. Similarly (...) with gestational diabetes in comparison with normal subjects. These findings underlined that 1-deoxysphingolipids (1-deoxySLs) and their ratios with C18SAdiene could be significantly correlated with the glucose load of OGTT and might be used as predictive biomarkers along with OGTT for the risk assessment of diabetes.

2017 EXCLI journal

35. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial Full Text available with Trip Pro

The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial This study investigated if inositol in a combination of myo-inositol and D-chiro-inositol would prevent gestational diabetes mellitus (GDM) in women with a family history of diabetes.This was a randomized controlled trial that examined whether inositol from the first antenatal visit prevents GDM. The trial was carried out in a single-center tertiary referral center. Women (...) with a family history of diabetes were enrolled at the first antenatal visit. They were randomized to the intervention group, which received a combination of 1,100 mg myo-inositol, 27.6 mg D-chiro-inositol, and 400 μg folic acid, or to the control group, which received 400 μg folic acid only. All women had an oral glucose tolerance test between 24 and 28 weeks' gestation. The primary end point was the incidence of GDM. Statistical analysis was carried out using SPSS Statistical Package version 20.Two

2017 EvidenceUpdates

36. Pregnancy Health: Lifestyle Interventions to Reduce the Risk of Gestational Diabetes

Pregnancy Health: Lifestyle Interventions to Reduce the Risk of Gestational Diabetes Pregnancy Health: Gestational Diabetes | The Community Guide Welcome to The Community Guide! Let us know what you think of the website by completing this . Open Navigation or Search form Search Search The Community Guide You are here » Systematic Review Topic Recommended (strong evidence) December 2017 Audience Adults Parents/Caregivers Setting Clinical/Health Systems Community Strategy Counseling Health (...) Education Pregnancy Health: Lifestyle Interventions to Reduce the Risk of Gestational Diabetes Tabs Snapshot Summary of CPSTF Finding The lifestyle interventions delivered during the first two trimesters of pregnancy to reduce the risk of gestational diabetes. The CPSTF finds Strong evidence of effectiveness for lifestyle interventions that provide supervised exercise classes, either alone or in combination with other components Sufficient evidence of effectiveness for lifestyle interventions

2017 Community Preventive Services Task Force

38. Perceived needs in women with gestational diabetes: A qualitative study Full Text available with Trip Pro

Perceived needs in women with gestational diabetes: A qualitative study Diabetes is the most common medical complication of pregnancy. It can be associated with many complications for mother and fetus. Gestational diabetes is also one of the main health issues in Iran. Therefore, the present study is aimed at a deeper understanding of women's experiences of gestational diabetes and their perceived needs to inform future lifestyle interventions.This qualitative content analysis study was carried (...) out in 2015. Participants were pregnant women diagnosed with gestational diabetes in the 24th to 36th week of pregnancy, who were referred to the clinics affiliated with Shahid Beheshti Medical Science University in Tehran, Iran. In-depth interviews were conducted with participants, using semi-structured questions. Interviews were audio taped and transcribed verbatim. Conventional content analysis was carried out for data analysis. Interviews continued until data saturation was obtained. Data were

2016 Electronic physician

39. Exercise and its role in gestational diabetes mellitus Full Text available with Trip Pro

Exercise and its role in gestational diabetes mellitus Gestational diabetes mellitus (GDM) refers to diabetes diagnosed in the second or third trimester of pregnancy that is not clearly either type 1 or type 2 diabetes. GDM is a common medical complication in pregnancy that has been rapidly increasing worldwide. GDM is associated with both short- and long-term health issues for both mothers and offspring. Consistent with type 2 diabetes, peripheral insulin resistance contributes

2016 Chronic diseases and translational medicine

40. Diagnosis, prevention and management of gestational diabetes mellitus Full Text available with Trip Pro

Diagnosis, prevention and management of gestational diabetes mellitus 29063042 2019 01 16 2095-882X 2 4 2016 Dec Chronic diseases and translational medicine Chronic Dis Transl Med Diagnosis, prevention and management of gestational diabetes mellitus. 199-203 10.1016/j.cdtm.2016.11.004 Wang Chen C Department of Obstetrics and Gynecology of Peking University First Hospital, Beijing 100034, China. Yang Hui-Xia HX Department of Obstetrics and Gynecology of Peking University First Hospital, Beijing (...) 100034, China. eng Editorial 2016 12 04 China Chronic Dis Transl Med 101679934 2095-882X Diagnosis Gestational diabetes mellitus Management Postpartum follow-up Prevention 2016 08 10 2017 10 25 6 0 2017 10 25 6 0 2017 10 25 6 1 epublish 29063042 10.1016/j.cdtm.2016.11.004 S2095-882X(16)30062-7 PMC5643832 Int J Gynaecol Obstet. 2010 Oct;111(1):37-40 20542272 Diabetes Care. 2003 Aug;26(8):2261-7 12882846 BMC Pregnancy Childbirth. 2014 Jan 22;14:41 24450389 Obstet Gynecol Clin North Am. 2007 Jun;34(2

2016 Chronic diseases and translational medicine