Latest & greatest articles for hydroxychloroquine

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Top results for hydroxychloroquine

1. Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: a randomized trial Full Text available with Trip Pro

Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: a randomized trial Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: a randomized trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health (...) ? Report format: Send at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Clin Infect Dis Actions . 2020 Oct 17;ciaa1571. doi: 10.1093/cid/ciaa1571. Online ahead of print. Hydroxychloroquine as pre-exposure

2021 EvidenceUpdates

2. Safety of Hydroxychloroquine Among Outpatient Clinical Trial Participants for COVID-19 Full Text available with Trip Pro

Safety of Hydroxychloroquine Among Outpatient Clinical Trial Participants for COVID-19 Safety of Hydroxychloroquine Among Outpatient Clinical Trial Participants for COVID-19 - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health information from CDC: Get (...) at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Open Forum Infect Dis Actions . 2020 Oct 19;7(11):ofaa500. doi: 10.1093/ofid/ofaa500. eCollection 2020 Nov. Safety of Hydroxychloroquine Among Outpatient Clinical

2021 EvidenceUpdates

3. A cluster-randomized trial of hydroxychloroquine for prevention of covid-19 Full Text available with Trip Pro

A cluster-randomized trial of hydroxychloroquine for prevention of covid-19 CDEI - A cluster-randomized trial of hydroxychloroquine for prevention of covid-19 — CDEI Open Menu Close Menu Open Menu Close Menu Dec 30 Written By Citation: Mitjà, O. , Corbacho-Monné, M., Ubals, M., Alemany, A., Suñer, C., & Tebé, C. et al. (2020). A cluster-randomized trial of hydroxychloroquine for prevention of covid-19. New England Journal Of Medicine . doi: 10.1056/nejmoa2021801 DOI: Journal impact factor (...) : 74.699 (New England Journal of Medicine) Full PICO and Limitations in text: Population: 2314 asymptomatic adults ≥18 years old with a recent history of close-contact exposure to a PCR-confirmed case patient with COVID-19, and an increased risk of infection (health care worker, household contact, a nursing home worker, or a nursing home resident). Intervention and Comparator Intervention: 1116 patients. Hydroxychloroquine (800mg once, followed by 400mg daily for 6 days). Comparator: 1198 patients

2021 Covid-19 Drug Evidence Initiative

4. A multicenter, randomized, open-label, controlled trial to evaluate the efficacy and tolerability of hydroxychloroquine and a retrospective study in adult patients with mild to moderate COVID-19

A multicenter, randomized, open-label, controlled trial to evaluate the efficacy and tolerability of hydroxychloroquine and a retrospective study in adult patients with mild to moderate COVID-19 CDEI - A multicenter, randomized, open-label, controlled trial to evaluate the efficacy and tolerability of hydroxychloroquine and a retrospective study in adult patients with mild to moderate coronavirus disease 2019 (COVID-19) — CDEI Open Menu Close Menu Open Menu Close Menu Dec 15 Written By Citation (...) : Chen, C. P. , Lin, Y. C., Chen, T. C., Tseng, T. Y., Wong, H. L., Kuo, C. Y., ... & Liao, C. S. (2020). A multicenter, randomized, open-label, controlled trial to evaluate the efficacy and tolerability of hydroxychloroquine and a retrospective study in adult patients with mild to moderate coronavirus disease 2019 (COVID-19). PloS one , 15 (12), e0242763. DOI: Journal Impact Factor: 2.740 (PloS one) Full PICO and Limitations in text: Population: 33 adult (20-79 years) patients diagnosed SARS-CoV-2

2021 Covid-19 Drug Evidence Initiative

5. Do zinc supplements enhance the clinical efficacy of hydroxychloroquine?: A randomized, multicenter trial Full Text available with Trip Pro

Do zinc supplements enhance the clinical efficacy of hydroxychloroquine?: A randomized, multicenter trial CDEI - Do zinc supplements enhance the clinical efficacy of hydroxychloroquine?: A randomized, multicenter trial — CDEI Open Menu Close Menu Open Menu Close Menu Dec 12 Written By Citation: Abd-Elsalam, S. , Soliman, S., Esmail, E. S., Khalaf, M., Mostafa, E. F., Medhat, M. A., . . . Hassany, S. M. (2020). Do zinc supplements enhance the clinical efficacy of hydroxychloroquine (...) ?: A randomized, multicenter trial. Biological Trace Element Research. DOI: Journal impact factor: 2.639 (Biological Trace Element Research) Clinical trial registry link : Full PICO and Limitations in text: Population: 191 hospitalized adult (≥18) patients with PCR confirmed COVID-19 infection. Intervention and Comparator Intervention: 96 patients. Zinc Sulfate (220mg/50mg elemental zinc orally twice daily) plus Hydroxychloroquine (400mg orally twice daily on day 1, then 200mg orally twice daily for 5 days

2020 Covid-19 Drug Evidence Initiative

6. Randomized double-blinded placebo-controlled trial of hydroxychloroquine with or without azithromycin for virologic cure of non-severe Covid-19 Full Text available with Trip Pro

Randomized double-blinded placebo-controlled trial of hydroxychloroquine with or without azithromycin for virologic cure of non-severe Covid-19 CDEI - Randomized double-blinded placebo-controlled trial of hydroxychloroquine with or without azithromycin for virologic cure of non-severe Covid-19 — CDEI Open Menu Close Menu Open Menu Close Menu Dec 13 Written By Citation: Omrani, A. S. , Pathan, S. A., Thomas, S. A., Harris, T. R., Coyle, P. V., Thomas, C. E., ... & Elmalik, A. (2020). Randomized (...) double-blinded placebo-controlled trial of hydroxychloroquine with or without azithromycin for virologic cure of non-severe Covid-19. EClinicalMedicine , 29 , 100645. DOI: Clinical trial registry link : Full PICO and Limitations in text: Population: 456 non-hospitalized adult (>18 years) patients diagnosed with PCR-confirmed SARS-CoV-2 infection and with no to mild symptoms. Interventions and Comparator Intervention: 152 patients. Hydroxychloroquine (HCQ) with placebo - Hydroxychloroquine 200mg q8h

2020 Covid-19 Drug Evidence Initiative

7. Hydroxychloroquine vs. azithromycin for hospitalized patients with COVID-19 (HAHPS): results of a randomized, active comparator trial Full Text available with Trip Pro

Hydroxychloroquine vs. azithromycin for hospitalized patients with COVID-19 (HAHPS): results of a randomized, active comparator trial CDEI - Hydroxychloroquine vs. azithromycin for hospitalized patients with COVID-19 (HAHPS): results of a randomized, active comparator trial — CDEI Open Menu Close Menu Open Menu Close Menu Nov 17 Written By Citation: Brown, S. M. , Peltan, I., Kumar, N., Leither, L., Webb, B. J., Starr, N., . . . Greene, T. (2020). Hydroxychloroquine vs. azithromycin (...) for hospitalized patients with COVID-19 (HAHPS): results of a randomized, active comparator trial. Annals of the American Thoracic Society . DOI: Journal impact factor: 4.836 (Annals of the American Thoracic Society) Clinical trial registry link : Full PICO and Limitations in text: Population: 85 hospitalized patients with laboratory-confirmed COVID-19 and active symptoms. Intervention and Comparator Intervention: 42 patients. Hydroxychloroquine 400mg BID on day 1, then 200mg BID for 4 days. Comparator: 43

2020 Covid-19 Drug Evidence Initiative

8. Effect of hydroxychloroquine on clinical status at 14 days in hospitalized patients with COVID-19 Full Text available with Trip Pro

Effect of hydroxychloroquine on clinical status at 14 days in hospitalized patients with COVID-19 CDEI - Effect of hydroxychloroquine on clinical status at 14 days in hospitalized patients with COVID-19 — CDEI Open Menu Close Menu Open Menu Close Menu Nov 22 Written By Citation: Self, W. , Semler, M., Leither, L., Casey, J., Angus, D., & Brower, R. et al. (2020). Effect of hydroxychloroquine on clinical status at 14 days in hospitalized patients with COVID-19. JAMA . DOI: Journal impact factor (...) : 45.540 (JAMA) Clinical trial registry link : Full PICO and Limitations in text: Population: 479 Patients > 18 years old, with laboratory confirmed SARS-CoV-2, with symptoms of respiratory illness for < 10 days and hospitalized for under 48 hours. Intervention and Comparator Intervention: 242 patients. Hydroxychloroquine (400 mg po BID x 1 day, then 200 mg BID x 4 days). Comparator: 237 patients. Placebo (same dosing regimen as above). Outcomes: Primary outcomes: Clinical status 14 days after

2020 Covid-19 Drug Evidence Initiative

9. Hydroxychloroquine and QTc prolongation in patients with COVID-19: A systematic review and meta-analysis Full Text available with Trip Pro

Hydroxychloroquine and QTc prolongation in patients with COVID-19: A systematic review and meta-analysis Hydroxychloroquine and QTc prolongation in patients with COVID-19: A systematic review and meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public (...) of print. Hydroxychloroquine and QTc prolongation in patients with COVID-19: A systematic review and meta-analysis , , , Affiliations Expand Affiliations 1 Department of Cardiology, VMMC & Safdarjung Hospital, New Delhi, India. 2 Department of Cardiology, Fortis Hospital, Mohali, Punjab, India. 3 Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India. 4 Department of Cardiology, Advanced Cardiac Centre, Post Graduate Institute of Medical Education

2020 EvidenceUpdates

10. Chloroquine and Hydroxychloroquine for the Treatment of COVID-19: a Systematic Review and Meta-analysis Full Text available with Trip Pro

Chloroquine and Hydroxychloroquine for the Treatment of COVID-19: a Systematic Review and Meta-analysis Chloroquine and Hydroxychloroquine for the Treatment of COVID-19: a Systematic Review and Meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public (...) and Hydroxychloroquine for the Treatment of COVID-19: a Systematic Review and Meta-analysis , , , , , , , , , , Affiliations Expand Affiliations 1 Department of Neurology, All India Institute of Medical Sciences, New Delhi, 110029, India. 2 Department of Community Medicine, NDMC Medical College, New Delhi, India. 3 Clinical Hematology, All India Institute of Medical Sciences, New Delhi, 110029, India. 4 Medical Oncology, All India Institute of Medical Sciences, New Delhi, 110029, India. 5 Pulmonary Medicine

2020 EvidenceUpdates

11. Hydroxychloroquine: did COVID-19 change GP prescribing?

Hydroxychloroquine: did COVID-19 change GP prescribing? Hydroxychloroquine: did COVID-19 change GP prescribing? - NPS MedicineWise Log In Menu During the COVID-19 pandemic, you need to continue to take your usual medicines and stay as healthy as possible. Health professionals also need to stay up to date with the latest evidence as it emerges. Our information hub has important information for everyone. Featured topics 02 Sep 2020 06 Aug 2020 03 Aug 2020 24 Jun 2020 09 Jun 2020 Featured article (...) address* Password* Log in Rate us How likely is it that you would recommend our site to a friend? Please help us to improve our services by answering the following question How likely is it that you would recommend our site to a friend? 0 1 2 3 4 5 6 7 8 9 10 0 = Not likely at all 10 = Extremely likely Please feel free to tell us why SUBMIT Hydroxychloroquine: did COVID-19 change GP prescribing? A study looking at prescribing patterns for hydroxychloroquine during the first months of the COVID-19

2020 National Prescribing Service Limited (Australia)

12. Treating COVID-19 with hydroxychloroquine (TEACH): A multicenter, double-blind randomized controlled trial in hospitalized patients Full Text available with Trip Pro

Treating COVID-19 with hydroxychloroquine (TEACH): A multicenter, double-blind randomized controlled trial in hospitalized patients CDEI - Treating COVID-19 with hydroxychloroquine (TEACH): A multicenter, double-blind randomized controlled trial in hospitalized patients — CDEI Open Menu Close Menu Open Menu Close Menu Nov 11 Written By Citation: Ulrich, R. J. , Troxel, A. B., Carmody, E., Eapen, J., Bäcker, M., DeHovitz, J. A., ... & Robbins, G. A. (2020, October). Treating COVID-19 (...) with hydroxychloroquine (TEACH): A multicenter, double-blind randomized controlled trial in hospitalized patients. In Open Forum Infectious Diseases (Vol. 7, No. 10, p. ofaa446). US: Oxford University Press. DOI: Journal impact factor: 3.656 (Open Forum Infectious Diseases) Clinical trial registry link : Full PICO and Limitations in text: Population: 128 hospitalized patients, ages 19 and older, with RT-PCR confirmed SARS-CoV-2 infection and at least one COVID-19 symptom. Intervention and Comparator Intervention: 67

2020 Covid-19 Drug Evidence Initiative

13. Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: a randomized trial Full Text available with Trip Pro

Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: a randomized trial CDEI - Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: A randomized trial — CDEI Open Menu Close Menu Open Menu Close Menu Sep 28 Written By Note: Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media (...) as established information (medRxiv). Citation: Rajasingham, R. , Bangdiwala, A. S., Nicol, M. R., … Lofgren, S. M. (2020). Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: A randomized trial. MedRxiv DOI: Full PICO and Limitations in text: Population: 1483 healthcare workers aged 18 years or older with ongoing exposure to persons with COVID-19. InterventionS and Comparator Intervention 1: 494 patients. Hydroxychloroquine 400mg divided into two 200mg doses separated by 6-8

2020 Covid-19 Drug Evidence Initiative

14. Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19. Full Text available with Trip Pro

Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19. Hydroxychloroquine and chloroquine have been proposed as treatments for coronavirus disease 2019 (Covid-19) on the basis of in vitro activity and data from uncontrolled studies and small, randomized trials.In this randomized, controlled, open-label platform trial comparing a range of possible treatments with usual care in patients hospitalized with Covid-19, we randomly assigned 1561 patients to receive hydroxychloroquine (...) and 3155 to receive usual care. The primary outcome was 28-day mortality.The enrollment of patients in the hydroxychloroquine group was closed on June 5, 2020, after an interim analysis determined that there was a lack of efficacy. Death within 28 days occurred in 421 patients (27.0%) in the hydroxychloroquine group and in 790 (25.0%) in the usual-care group (rate ratio, 1.09; 95% confidence interval [CI], 0.97 to 1.23; P = 0.15). Consistent results were seen in all prespecified subgroups of patients

2020 NEJM

15. Effect of hydroxychloroquine with or without azithromycin on the mortality of coronavirus disease 2019 (COVID-19) patients: a systematic review and meta-analysis Full Text available with Trip Pro

Effect of hydroxychloroquine with or without azithromycin on the mortality of coronavirus disease 2019 (COVID-19) patients: a systematic review and meta-analysis Effect of hydroxychloroquine with or without azithromycin on the mortality of coronavirus disease 2019 (COVID-19) patients: a systematic review and meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced (...) . 2020 Aug 26;S1198-743X(20)30505-X. doi: 10.1016/j.cmi.2020.08.022. Online ahead of print. Effect of hydroxychloroquine with or without azithromycin on the mortality of coronavirus disease 2019 (COVID-19) patients: a systematic review and meta-analysis , , , , , Affiliations Expand Affiliations 1 CESP (Centre for Research in Epidemiology and Population Health), Faculté de Médecine-Université Paris-Sud, Faculté de Médecine-UVSQ, INSERM, Université Paris Saclay, Villejuif, France; Gustave Roussy

2020 EvidenceUpdates

16. Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial Full Text available with Trip Pro

Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial CDEI - Hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial — CDEI Open Menu Close Menu Open Menu Close Menu Apr 21 Written By Note: Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information (...) (medRxiv). Citation: Chen, Z., Hu, J., Zhang, Z., Jiang, S., Han, S., Yan, D., ... & Zhang, Z. (2020). Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial. medRxiv. DOI: Full PICO and Limitations in text: Population: 62 adult (age ≥ 18), hospitalized patients with confirmed RT-PCR of SARS-CoV-2, chest CT with pneumonia, and mild illness (i.e. SaO2/SPO2 ratio > 93% or PaO2/FIO2 ratio > 300 mmHg on room air). Intervention: 31 patients received

2020 Covid-19 Drug Evidence Initiative

17. Efficacy and safety of chloroquine or hydroxychloroquine in moderate type of COVID-19: a prospective open-label randomized controlled study Full Text available with Trip Pro

Efficacy and safety of chloroquine or hydroxychloroquine in moderate type of COVID-19: a prospective open-label randomized controlled study CDEI - Efficacy and safety of chloroquine or hydroxychloroquine in moderate type of COVID-19 — CDEI Open Menu Close Menu Open Menu Close Menu Jun 26 Written By Note: Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should (...) not be reported in news media as established information (medRxiv). Citation: Chen, L. , Zhang, Z., Fu, J., Feng, Z., Zhang, S., ... Yin, Z. (2020). Efficacy and safety of chloroquine or hydroxychloroquine in moderate type of COVID-19: a prospective open-label randomized controlled study. medRxiv. DOI: Full PICO and Limitations in text: Population: 48 patients aged 18 to 75 years with moderate COVID-19, diagnosed by positive RT-PCR or with CT scan of the chest for lung changes characteristic of COVID-19

2020 Covid-19 Drug Evidence Initiative

18. Hydroxychloroquine in nonhospitalized adults with early COVID-19: a randomized trial

Hydroxychloroquine in nonhospitalized adults with early COVID-19: a randomized trial CDEI - Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19: A Randomized Trial — CDEI Open Menu Close Menu Open Menu Close Menu Jul 18 Written By Citation: Skipper CP , Pastick KA, Engen NW, et al. (2020). Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19: A Randomized Trial. Ann Intern Med. DOI: Full PICO and Limitations in text: Population: 491 nonhospitalized adults (≥18 years (...) ) with ≤4 days of symptoms and either confirmed SARS-CoV-2 infection or compatible symptoms after high-risk exposure to a person with confirmed COVID-19 within the past 14 days. Interventions and Comparator Intervention: 244 patients were randomized to receive hydroxychloroquine 800 mg PO once, then 600 mg PO 6 to 8 hours later, then 600 mg PO once daily for 4 more days (5 days in total). Comparator: 247 patients were randomized to receive placebo (folic acid 400 mcg at US sites, lactose at Canadian

2020 Covid-19 Drug Evidence Initiative

19. Hydroxychloroquine in the treatment of COVID-19: a multicenter randomized controlled study Full Text available with Trip Pro

Hydroxychloroquine in the treatment of COVID-19: a multicenter randomized controlled study CDEI - Hydroxychloroquine in the treatment of COVID-19: a multicenter randomized controlled study — CDEI Open Menu Close Menu Open Menu Close Menu Aug 31 Written By Citation: Abd-Elsalam, S. , Esmail, E. S., Khalaf, M., Abdo, E. F., Medhat, M. A., Abd El Ghafar, M. S., ... & Alboraie, M. (2020). Hydroxychloroquine in the treatment of COVID-19: a multicenter randomized controlled study. The American (...) Journal of Tropical Medicine and Hygiene , tpmd200873. DOI: Full PICO and Limitations in text: Population: 194 hospitalized patients with suspected or confirmed COVID-19 infection. Intervention and Comparator Intervention: 97 patients were randomized to receive standard of care plus hydroxychloroquine 400mg twice daily on day 1, followed by 200mg twice daily for 15 days. Comparator: 97 patients were randomized to receive standard of care for 15 days. Outcomes: Primary outcomes: (1) Recovery within 28

2020 Covid-19 Drug Evidence Initiative

20. Safety and Efficacy of Hydroxychloroquine in COVID-19: A Systematic Review and Meta-Analysis Full Text available with Trip Pro

Safety and Efficacy of Hydroxychloroquine in COVID-19: A Systematic Review and Meta-Analysis Safety and Efficacy of Hydroxychloroquine in COVID-19: A Systematic Review and Meta-Analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health information from (...) : Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation J Clin Med Res Actions . 2020 Aug;12(8):483-491. doi: 10.14740/jocmr4233. Epub 2020 Jul 4. Safety and Efficacy of Hydroxychloroquine in COVID-19: A Systematic Review

2020 EvidenceUpdates