Latest & greatest articles for ibuprofen

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Top results for ibuprofen

21. Ibuprofen plus paracetamol versus ibuprofen in acute low back pain: a randomized open label multicenter clinical study. (Abstract)

Ibuprofen plus paracetamol versus ibuprofen in acute low back pain: a randomized open label multicenter clinical study. to estimate whether combination of ibuprofen and paracetamol is more effective than ibuprofen in monotherapy, in the treatment of acute low back pain.80 adult patients with acute low back pain were randomized into two subgroups. In the first subgroup, 40 patients were treated with ibuprofen 400mg three times a day (TID), whilst patients in the second subgroup (n=40) were (...) treated with a fixed-dose combination tablet of ibuprofen 200mg plus paracetamol 325mg TID, for three consecutive days. Patients were followed for another 7 days. Efficacy and tolerability of both treatment options was assessed.A statistically significant decrease in pain intensity, assessed using a visual analogue scale (p<0.001), as well as the 5-point Likert scale, was noticed in both subgroups of patients. However, intensity of pain on Day 4 was significantly lower in patients treated

2016 Acta reumatologica portuguesa Controlled trial quality: uncertain

22. Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis. Full Text available with Trip Pro

Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis. The cardiovascular safety of celecoxib, as compared with nonselective nonsteroidal antiinflammatory drugs (NSAIDs), remains uncertain.Patients who required NSAIDs for osteoarthritis or rheumatoid arthritis and were at increased cardiovascular risk were randomly assigned to receive celecoxib, ibuprofen, or naproxen. The goal of the trial was to assess the noninferiority of celecoxib with regard to the primary composite (...) group (852±103 mg), or the ibuprofen group (2045±246 mg) for a mean treatment duration of 20.3±16.0 months and a mean follow-up period of 34.1±13.4 months. During the trial, 68.8% of the patients stopped taking the study drug, and 27.4% of the patients discontinued follow-up. In the intention-to-treat analyses, a primary outcome event occurred in 188 patients in the celecoxib group (2.3%), 201 patients in the naproxen group (2.5%), and 218 patients in the ibuprofen group (2.7%) (hazard ratio

2016 NEJM Controlled trial quality: predicted high

23. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. Full Text available with Trip Pro

Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. Studies have suggested an association between frequent acetaminophen use and asthma-related complications among children, leading some physicians to recommend that acetaminophen be avoided in children with asthma; however, appropriately designed trials evaluating this association in children are lacking.In a multicenter, prospective, randomized, double-blind, parallel-group trial, we enrolled 300 children (age range (...) , 12 to 59 months) with mild persistent asthma and assigned them to receive either acetaminophen or ibuprofen when needed for the alleviation of fever or pain over the course of 48 weeks. The primary outcome was the number of asthma exacerbations that led to treatment with systemic glucocorticoids. Children in both groups received standardized asthma-controller therapies that were used in a simultaneous, factorially linked trial.Participants received a median of 5.5 doses (interquartile range, 1.0

2016 NEJM Controlled trial quality: predicted high

24. 400 mg Ibuprofen/1000 mg Acetaminophen (Paracetamol) Is Suggested Effective Dosage for Ibuprofen/Acetaminophen Combination Therapy in Postoperative Pain Reduction

400 mg Ibuprofen/1000 mg Acetaminophen (Paracetamol) Is Suggested Effective Dosage for Ibuprofen/Acetaminophen Combination Therapy in Postoperative Pain Reduction UTCAT2994, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title 400 mg Ibuprofen/1000 mg Acetaminophen (Paracetamol) Is Suggested Effective Dosage for Ibuprofen/Acetaminophen Combination Therapy in Postoperative Pain Reduction Clinical Question In patients (...) receiving acetaminophen (paracetamol) and ibuprofen combination therapy, what is the effective dosage to relieve postoperative pain? Clinical Bottom Line For patients with postoperative pain, 400 mg ibuprofen/1000 mg acetaminophen (paracetamol) is the suggested effective dosage for short-term pain management. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Mehlisch/2010 234 patients post extraction

2016 UTHSCSA Dental School CAT Library

25. Esophageal ulcer induced by ibuprofen tablets Full Text available with Trip Pro

Esophageal ulcer induced by ibuprofen tablets 29063015 2018 11 13 2095-882X 1 4 2015 Dec Chronic diseases and translational medicine Chronic Dis Transl Med Esophageal ulcer induced by ibuprofen tablets. 245-246 10.1016/j.cdtm.2015.11.004 Xu Xiao-Ling XL Department of Gastroenterology, Subei People's Hospital, Clinical Medical School, Yangzhou University Affiliated Hospital, Yangzhou, Jiangsu, China. Zhu Hai-Hang HH Department of Gastroenterology, Subei People's Hospital, Clinical Medical School (...) , Yangzhou University Affiliated Hospital, Yangzhou, Jiangsu, China. Yin Jian J Department of Gastroenterology, Subei People's Hospital, Clinical Medical School, Yangzhou University Affiliated Hospital, Yangzhou, Jiangsu, China. eng Journal Article 2016 01 21 China Chronic Dis Transl Med 101679934 2095-882X Esophageal ulcer Ibuprofen Non-steroidal antiinflammatory drugs 2015 09 01 2017 10 25 6 0 2016 1 21 0 0 2016 1 21 0 1 epublish 29063015 10.1016/j.cdtm.2015.11.004 S2095-882X(15)00070-5 PMC5643597

2016 Chronic diseases and translational medicine

26. Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen

Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen Prescrire IN ENGLISH - Spotlight ''Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen'', 1 January 2016 {1} {1} {1} | | > > > Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |  (...)  |   |   |   |   |   |   |  Spotlight Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen When pain medication is required, paracetamol (alias acetaminophen) is the reference drug. Among the nonsteroidal anti-inflammatories (NSAIDs), naproxen or ibuprofen (not exceeding 1200 mg a day) are the drugs that carry the least exposure to cardiac disorders. When pain medication is needed

2016 Prescrire

27. Systematic review: Ibuprofen for the treatment of TTH

Systematic review: Ibuprofen for the treatment of TTH Ibuprofen for the treatment of TTH | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search (...) for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Ibuprofen for the treatment of TTH Article Text Therapeutics/Prevention Systematic review Ibuprofen for the treatment of TTH Roy G Beran Statistics from Altmetric.com Commentary on: Derry S , Wiffen PJ , Moore RA , et al . Ibuprofen for acute treatment of episodic tension-type headache in adults

2016 Evidence-Based Medicine

28. High-dose ibuprofen (?2400mg/day): small increase in cardiovascular risk

High-dose ibuprofen (?2400mg/day): small increase in cardiovascular risk High-dose ibuprofen (≥2400mg/day): small increase in cardiovascular risk - GOV.UK GOV.UK uses cookies to make the site simpler. or Search High-dose ibuprofen (≥2400mg/day): small increase in cardiovascular risk EU review confirms that the cardiovascular risk of high-dose ibuprofen (≥2400mg/day) is similar to COX 2 inhibitors and diclofenac. Published 26 June 2015 From: Therapeutic area: , , , Contents When prescribing (...) or dispensing ibuprofen: avoid use of high-dose ibuprofen (≥2400 mg per day) in patients with established: ischaemic heart disease peripheral arterial disease cerebrovascular disease congestive heart failure (New York Heart Association [NYHA] classification II-III) uncontrolled hypertension review the treatment of patients with the above conditions who are taking high-dose ibuprofen at their next routine appointment carefully consider the benefits and risks before starting long-term ibuprofen treatment

2015 MHRA Drug Safety Update

29. Fracture pain relief for kids? Ibuprofen does it better

Fracture pain relief for kids? Ibuprofen does it better Fracture pain relief for kids? Ibuprofen does it better Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Fracture pain relief for kids? Ibuprofen does it better View/ Open Date 2010-05 Format Metadata Abstract Use ibuprofen instead of acetaminophen with codeine

2015 PURLS

30. Randomised controlled trial: Postfracture pain in children can be adequately managed with ibuprofen

Randomised controlled trial: Postfracture pain in children can be adequately managed with ibuprofen Postfracture pain in children can be adequately managed with ibuprofen | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers (...) of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Postfracture pain in children can be adequately managed with ibuprofen Article Text Therapeutics/Prevention Randomised controlled trial Postfracture pain in children can be adequately managed with ibuprofen Kevin B L

2015 Evidence-Based Medicine

31. For Post-Dental Extraction Pain, Co-therapy with Acetaminophen and Ibuprofen is More Effective in Pain Management than Acetaminophen or Ibuprofen Alone

For Post-Dental Extraction Pain, Co-therapy with Acetaminophen and Ibuprofen is More Effective in Pain Management than Acetaminophen or Ibuprofen Alone UTCAT2734, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title For Post-Dental Extraction Pain, Co-therapy with Acetaminophen and Ibuprofen is More Effective in Pain Management than Acetaminophen or Ibuprofen Alone Clinical Question In patients following a dental extraction (...) is the post-operative administration of combined acetaminophen and ibuprofen better than therapy with acetaminophen or ibuprofen alone for pain management? Clinical Bottom Line The post-operative use combined acetaminophen and ibuprofen provides superior pain relief compared to acetaminophen or ibuprofen alone. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Bailey/2013 Patient Group 2,241 patients ages 16-65

2014 UTHSCSA Dental School CAT Library

32. Ibuprofen

Ibuprofen USE OF IBUPROFEN IN PREGNANCY 0344 892 0909 USE OF IBUPROFEN IN PREGNANCY (Date of issue: December 2013 , Version: 1.1 ) This is a UKTIS monograph for use by health care professionals. For case-specific advice please contact UKTIS on 0344 892 0909. To report an exposure please download and complete a . Please encourage all women to complete an . A corresponding patient information leaflet on is available at . Summary Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) used (...) to treat acute and chronic pain, and in the management of rheumatoid arthritis. Studies of NSAIDs as a group have identified an association between use in pregnancy and congenital malformation, specifically cardiovascular defects. However, the available data are conflicting and limited, and firm associations are yet to be concluded. Data specifically relating to maternal ibuprofen use in pregnancy are confounded and conflicting. Studies which have investigated overall rates of malformation have

2014 UK Teratology Information Service

33. Randomised controlled trial: Neither ibuprofen nor steam improves symptom control compared with paracetamol in patients with acute respiratory tract infections in primary care

Randomised controlled trial: Neither ibuprofen nor steam improves symptom control compared with paracetamol in patients with acute respiratory tract infections in primary care Neither ibuprofen nor steam improves symptom control compared with paracetamol in patients with acute respiratory tract infections in primary care | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser (...) at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Neither ibuprofen nor steam improves symptom control compared

2014 Evidence-Based Medicine

34. Systematic review and meta-analysis: Limited evidence that single-dose oral ibuprofen plus codeine is more effective for postoperative pain than either drug alone Full Text available with Trip Pro

Systematic review and meta-analysis: Limited evidence that single-dose oral ibuprofen plus codeine is more effective for postoperative pain than either drug alone Limited evidence that single-dose oral ibuprofen plus codeine is more effective for postoperative pain than either drug alone | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use (...) cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Limited evidence that single-dose oral ibuprofen plus codeine is more effective for postoperative pain than

2014 Evidence-Based Nursing

35. Cohort study: Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern

Cohort study: Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern Article Text Aetiology Cohort study

2014 Evidence-Based Medicine

36. A Prophylactic Single Dose of 200mg Ibuprofen or 20mg Tenoxicam Administration Before Endodontic Treatment reduces Postoperative Pain at 6 hours after Treatment

A Prophylactic Single Dose of 200mg Ibuprofen or 20mg Tenoxicam Administration Before Endodontic Treatment reduces Postoperative Pain at 6 hours after Treatment UTCAT2593, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title A Prophylactic Single Dose of 200mg Ibuprofen or 20mg Tenoxicam Administration Before Endodontic Treatment Reduces Postoperative Pain at 6 Hours After Treatment Clinical Question Do preoperative pain (...) medications reduce pain in patients with endodontic treatment compared with patients with no postoperative pain? Clinical Bottom Line 200mg Ibuprofen or 20mg of tenoxicam reduces postoperative pain at 6 hours after Endodontic treatment but no significant difference at 12,24,48 and 72 hours. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Arslan/2011 48 Randomized double-blinded clinical trail Key results 48

2013 UTHSCSA Dental School CAT Library

37. Prophylactic Compared With Therapeutic Ibuprofen Analgesia in First-Trimester Medical Abortion: A Randomized Controlled Trial (Abstract)

Prophylactic Compared With Therapeutic Ibuprofen Analgesia in First-Trimester Medical Abortion: A Randomized Controlled Trial To compare the effectiveness of two oral analgesic regimens in first-trimester medical abortion.We randomly assigned 250 participants undergoing first-trimester abortion with mifepristone and misoprostol at three clinics to two ibuprofen regimens: therapeutic (800 mg every 4-6 hours as needed for pain) or prophylactic (800 mg starting 1 hour before the misoprostol dose (...) , then every 4-6 hours for 48 hours regardless of pain, then as needed). We asked each participant to record her maximum pain on a scale of 0-10 daily thereafter.Of participants assigned to the prophylactic and therapeutic regimens, 111 of 123 (90%) and 117 of 127 (92%), respectively, provided follow-up data. More than 80% of the participants in each group complied with their assigned treatment. Participants in the prophylactic group used substantially more ibuprofen than those in the therapeutic group

2013 EvidenceUpdates Controlled trial quality: predicted high

38. Enteral Feeding during Indomethacin and Ibuprofen Treatment of a Patent Ductus Arteriosus Full Text available with Trip Pro

Enteral Feeding during Indomethacin and Ibuprofen Treatment of a Patent Ductus Arteriosus To test the hypothesis that infants who are just being introduced to enteral feedings will advance to full enteral nutrition at a faster rate if they receive "trophic" (15 mL/kg/d) enteral feedings while receiving indomethacin or ibuprofen treatment for patent ductus arteriosus.Infants were eligible for the study if they were 23(1/7)-30(6/7) weeks' gestation, weighed 401-1250 g at birth, received maximum (...) enteral volumes ≤60 mL/kg/d, and were about to be treated with indomethacin or ibuprofen. A standardized "feeding advance regimen" and guidelines for managing feeding intolerance were followed at each site (N = 13).Infants (N = 177, 26.3 ± 1.9 weeks' mean ± SD gestation) were randomized at 6.5 ± 3.9 days to receive "trophic" feeds ("feeding" group, n = 81: indomethacin 80%, ibuprofen 20%) or no feeds ("fasting [nil per os]" group, n = 96: indomethacin 75%, ibuprofen 25%) during the drug administration

2013 EvidenceUpdates Controlled trial quality: uncertain

39. For Patients With Dental Pain, Combination Therapy With Ibuprofen And Acetaminophen Is More Effective In Producing Analgesia Than Monotherapy With Ibuprofen Alone

For Patients With Dental Pain, Combination Therapy With Ibuprofen And Acetaminophen Is More Effective In Producing Analgesia Than Monotherapy With Ibuprofen Alone UTCAT2379, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title For Patients With Dental Pain, Combination Therapy With Ibuprofen And Acetaminophen Is More Effective In Producing Analgesia Than Monotherapy With Ibuprofen Alone Clinical Question In patients (...) with inflammatory pain, does the combination of ibuprofen and acetaminophen compared to ibuprofen alone produce greater analgesia? Clinical Bottom Line Combination therapy with ibuprofen and acetaminophen produces greater analgesia than ibuprofen alone in patients with inflammatory pain. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Daniels/2011 678 patients at least 16 years old with at least 3 impacted 3rd

2013 UTHSCSA Dental School CAT Library

40. Does Combination Treatment With Ibuprofen and Acetaminophen Improve Fever Control?

Does Combination Treatment With Ibuprofen and Acetaminophen Improve Fever Control? SystematicReviewSnapshot TAKE-HOME MESSAGE Combination treatment with ibuprofen and acetaminophen is bene?cial over either agent alone for sustained fever reduction in children older than 6 months. METHODS DATA SOURCES The author searched MEDLINE (1948 to May 2011) and EMBASE (1980 to May 2011). Additional hand searches of references from the UK National Institute for Health and Clinical Excellence guidelines (...) Standards of Re- porting Trials (CONSORT) crite- ria to score the quality of the included trials and abstract the data. Does Combination Treatment With Ibuprofen and Acetaminophen Improve Fever Control? EBEM Commentator Rohith R. Malya, MD, MSc Department of Emergency Medicine University of Texas at Houston Houston, TX Results Seventrialswereretrievedandallmet the inclusion criteria and most of the itemsontheCONSORTchecklist.Dif- ferences in dosing interval limited di- rect comparison between any 2

2013 Annals of Emergency Medicine Systematic Review Snapshots