Latest & greatest articles for infants

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on infants or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on infants and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for infants

1. Evidence base for point-of-care ultrasound (POCUS) for diagnosis of skull fractures in children: a systematic review and meta-analysis Full Text available with Trip Pro

. doi: 10.1136/emermed-2020-209887. Online ahead of print. Evidence base for point-of-care ultrasound (POCUS) for diagnosis of skull fractures in children: a systematic review and meta-analysis , , , Affiliations Expand Affiliations 1 Emergency Medicine, Erasmus Medical Center, Rotterdam, Zuid-Holland, The Netherlands g.alexandridis@erasmusmc.nl. 2 Emergency Medicine, Franciscus Gasthuis en Vlietland, Rotterdam, Zuid-Holland, The Netherlands. 3 Pediatrics, Franciscus Gasthuis en Vlietland, Rotterdam (...) limitations. Overall, the evidence suggests that POCUS is a valid option for diagnosing skull fractures in children visiting the ED after blunt head injury. Keywords: CT/MRI; Trauma; head; imaging; paediatric emergency medicine; paediatric injury; paediatrics; ultrasound. © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. Conflict of interest statement Competing interests: None declared. Similar articles Parri N, Crosby BJ, Mills L, Soucy Z, Musolino AM, Da Dalt L

2021 EvidenceUpdates

2. Randomized Controlled Trial of High-Flow Nasal Cannula in Preterm Infants After Extubation

in Preterm Infants After Extubation , , , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Department of Pediatrics and uchiyama.atsushi@tsc.u-tokai.ac.jp. 2 Department of Neonatal Medicine, Maternal and Perinatal Center, Tokyo Women's Medical University, Tokyo, Japan. 3 Department of Neonatology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan. 4 Department of Pediatrics, Saitama Medical Center and Saitama Medical University, Saitama, Japan; uchiyama.atsushi@tsc.u-tokai.ac.jp (...) . 5 Department of Pediatrics, Saitama Medical Center and Saitama Medical University, Saitama, Japan. 6 Department of Pediatrics and Child Health, School of Medicine, Nihon University, Tokyo, Japan. 7 Department of Pediatrics, Iino Women's and Children's Hospital, Tokyo, Japan. 8 Department of Neonatology, Nagaoka Red Cross Hospital, Niigata, Japan. 9 Department of Pediatrics, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan; and. 10 Division of Neonatology, Center

2021 EvidenceUpdates

3. Family Integrated Care for Preterm Infants in China: A Cluster Randomized Controlled Trial

and Childcare Hospital, Lanzhou, Gansu, China. 10 Department of Pediatrics, Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China. 11 Department of Neonatology, Hunan Provincial People's Hospital, Changsha, Hunan, China. 12 Department of Neonatology, Kunming Maternal and Child Healthcare Hospital, Kunming, Yunnan, China. 13 Chinese Neonatal Network, Fudan Children's Hospital, Shanghai, China. 14 Maternal-Infant Care Research Centre, Mount Sinai Hospital, Toronto, Ontario, Canada. 15 Maternal (...) , Gansu Provincial Maternity and Childcare Hospital, Lanzhou, Gansu, China. 10 Department of Pediatrics, Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China. 11 Department of Neonatology, Hunan Provincial People's Hospital, Changsha, Hunan, China. 12 Department of Neonatology, Kunming Maternal and Child Healthcare Hospital, Kunming, Yunnan, China. 13 Chinese Neonatal Network, Fudan Children's Hospital, Shanghai, China. 14 Maternal-Infant Care Research Centre, Mount Sinai Hospital

2021 EvidenceUpdates

4. Effectiveness of onabotulinumtoxinA (BOTOX) in pediatric patients experiencing migraines: a randomized, double-blinded, placebo-controlled crossover study in the pediatric pain population

Effectiveness of onabotulinumtoxinA (BOTOX) in pediatric patients experiencing migraines: a randomized, double-blinded, placebo-controlled crossover study in the pediatric pain population Effectiveness of onabotulinumtoxinA (BOTOX) in pediatric patients experiencing migraines: a randomized, double-blinded, placebo-controlled crossover study in the pediatric pain population - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features (...) Format Share Permalink Copy Page navigation Reg Anesth Pain Med Actions . 2021 Jan;46(1):41-48. doi: 10.1136/rapm-2020-101605. Epub 2020 Oct 26. Effectiveness of onabotulinumtoxinA (BOTOX) in pediatric patients experiencing migraines: a randomized, double-blinded, placebo-controlled crossover study in the pediatric pain population , , , , Affiliations Expand Affiliations 1 Department of Anesthesiology & Perioperative Care, University of California Irvine Health, Orange, CA, 92868 ssshah1@hs.uci.edu

2021 EvidenceUpdates

5. Parent utilization of ImPACT intervention strategies is a mediator of proximal then distal social communication outcomes in younger siblings of children with ASD Full Text available with Trip Pro

Parent utilization of ImPACT intervention strategies is a mediator of proximal then distal social communication outcomes in younger siblings of children with ASD Parent utilization of ImPACT intervention strategies is a mediator of proximal then distal social communication outcomes in younger siblings of children with ASD - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced (...) Actions . 2021 Jan;25(1):44-57. doi: 10.1177/1362361320946883. Epub 2020 Aug 18. Parent utilization of ImPACT intervention strategies is a mediator of proximal then distal social communication outcomes in younger siblings of children with ASD , , Affiliations Expand Affiliations 1 Vanderbilt University, USA. 2 University of Washington, USA. 3 Harvard Medical School, USA. 4 Boston Children's Hospital, USA. PMID: 32811160 DOI: Item in Clipboard Parent utilization of ImPACT intervention strategies

2021 EvidenceUpdates

6. Effect of Parent Training on Health-Related Quality of Life in Preschool Children With Attention-Deficit/Hyperactivity Disorder: A Secondary Analysis of Data From a Randomized Controlled Trial

HRQoL in early childhood. PT for ADHD has the potential to improve HRQoL independently of its effects on ADHD symptoms. Clinical trial registration information: A Controlled Study of Parent Training in the Treatment of ADHD in Young Children (D'SNAPP); http://clinicaltrial.gov/; . Keywords: attention-deficit/hyperactivity disorder; health-related quality of life; parent training; preschool children. Copyright © 2020 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All (...) options Format Share Permalink Copy Page navigation J Am Acad Child Adolesc Psychiatry Actions . 2020 Jun 4;S0890-8567(20)30336-1. doi: 10.1016/j.jaac.2020.04.014. Online ahead of print. Effect of Parent Training on Health-Related Quality of Life in Preschool Children With Attention-Deficit/Hyperactivity Disorder: A Secondary Analysis of Data From a Randomized Controlled Trial , , , , , Affiliations Expand Affiliations 1 Aarhus University, Denmark. Electronic address: livlar@rm.dk. 2 University

2021 EvidenceUpdates

7. Group Sessions or Home Visits for Early Childhood Development in India: A Cluster RCT

. PMID: 33148771 PMCID: PMC7786825 (available on 2021-12-01 ) DOI: Item in Clipboard Randomized Controlled Trial Group Sessions or Home Visits for Early Childhood Development in India: A Cluster RCT Sally Grantham-McGregor et al. Pediatrics . 2020 Dec . Show details Display options Display options Format Pediatrics Actions . 2020 Dec;146(6):e2020002725. doi: 10.1542/peds.2020-002725. Epub 2020 Nov 4. Authors , , , , , , , , , , , , , Affiliations 1 Institute for Global Health, University College (...) : Poor early childhood development in low- and middle-income countries is a major public health problem. Efficacy trials have shown the potential of early childhood development interventions but scaling up is costly and challenging. Guidance on effective interventions' delivery is needed. In an open-label cluster-randomized control trial, we compared the effectiveness of weekly home visits and weekly mother-child group sessions. Both included nutritional education, whose effectiveness was tested

2021 EvidenceUpdates

8. The use of force and setting limits for children and youth in residential child care and foster care

The use of force and setting limits for children and youth in residential child care and foster care The use of force and setting limits for children and youth in residential child care and foster care - NIPH Search for: Søk Menu To top level Close Infectious diseases & Vaccines Mental & Physical health Environment & Lifestyle Health in Norway Quality & Knowledge Research & Access to data About NIPH Close The use of force and setting limits for children and youth in residential child care (...) and foster care Subscribe me! You have subscribed to alerts about: The use of force and setting limits for children and youth in residential child care and foster care Oops, something went wrong... ... contact nettredaksjon@fhi.no. ... reload the page and try again- Mapping review The use of force and setting limits for children and youth in residential child care and foster care: a systematic scoping review Published 25.09.2020 Bufdir commissioned a review of the research that exists on the use of force

2021 Norwegian Institute of Public Health

9. Children and youths’ involvement in child welfare services

Children and youths’ involvement in child welfare services Children and youths’ involvement in child welfare services - NIPH Search for: Søk Menu To top level Close Infectious diseases & Vaccines Mental & Physical health Environment & Lifestyle Health in Norway Quality & Knowledge Research & Access to data About NIPH Close Children and youths’ involvement in child welfare services Subscribe me! You have subscribed to alerts about: Children and youths’ involvement in child welfare services Oops (...) , something went wrong... ... contact nettredaksjon@fhi.no. ... reload the page and try again- Mapping review Children and youths’ involvement in child welfare services: a systematic mapping review Published 02.11.2020 The Norwegian Directorate for Children, Youth and Family Af-fairs (Bufdir) commissioned the Norwegian Institute of Public Health to map out research that has examined children and young people's user involvement within the child welfare services. The Norwegian Directorate for Children

2021 Norwegian Institute of Public Health

10. COVID-19 in children and the role of school settings in transmission - first update

understand infection and antibody dynamics. Investigations of cases identified in school settings suggest that child to child transmission in schools is uncommon and not the primary cause of SARS-CoV-2 infection in children whose onset of infection coincides with the period during which they are attending school, particularly in preschools and primary schools. If appropriate physical distancing and hygiene measures are applied, schools are unlikely to be more effective propagating environments than other (...) Technical report 6 Aug 2020 Cite: COVID-19 in children and the role of school settings in COVID-19 transmission, 6 August 2020. Stockholm: ECDC; 2020. The aim of this document is to provide an overview of the epidemiology and disease characteristics of COVID-19 in children (0-18 years) in EU/EEA countries and the United Kingdom (UK), and an assessment of the role of childcare (preschools; ages 0-<5 years) and educational (primary and secondary schools; ages 5-18 years) settings in COVID-19 transmission

2021 European Centre for Disease Prevention and Control - Covid-19 Guidance

11. COVID-19: paediatric surveillance

COVID-19: paediatric surveillance COVID-19: paediatric surveillance - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Coronavirus guidance is being updated. Read Stay alert. Control the virus. Save lives. Guidance COVID-19: paediatric surveillance Description and contact details of PHE (...) paediatric surveillance programmes for COVID-19. Published 27 April 2020 From: Paediatric surveillance for . If you would like more information about the surveillance, please contact Dr Shamez Ladhani at . 2. Clinical follow up of laboratory-confirmed cases in neonates up to 28 days of age . Paediatricians across the UK and Ireland will receive weekly emails from the . For more information about the . At the end of the surveillance, cases will be linked to a similar surveillance of . For more information

2021 Public Health England

12. Melatonin (Slenyto) - Treatment of insomnia in children and adolescents aged 2 to 18 years with autism spectrum disorder and / or Smith-Magenis syndrome

report. Melatonin prolonged- release (Slenyto). 26 July 2018, EMA/556280/2018 www.ema.europa.eu 3. Gringras P, Nir T, Breddy, J, et al. Efficacy and safety of pediatric prolonged-release melatonin for insomnia in children with autism spectrum disorder. J Am Acad Child Adolesc Psychiatry 2017; 56: 948-57. 4. Maras A, Schroder CM, Malow BA, et al. Long-Term Efficacy and Safety of Pediatric Prolonged- Release Melatonin for Insomnia in Children with Autism Spectrum Disorder. J Child Adoles (...) in the past two years. The Smith-Magenis Syndrome Foundation UK has received 1.9% pharmaceutical company funding in the past two years, including from the submitting company. ? Getting to sleep and staying asleep is a significant issue for many children with Autistic Spectrum Disorder (ASD), while a child with Smith-Magenis Syndrome (SMS) has a different sleeping pattern to the rest of their family and community. The impact on affected children includes anxiety and distress at night, and has a serious

2021 Scottish Medicines Consortium

13. The use of link workers in child welfare services

nettredaksjon@fhi.no. ... reload the page and try again- Mapping review The use of link workers in child welfare services: a systematic mapping review Published 18.11.2020 The purpose of this systematic mapping review is to classify and describe research about link workers working in the field of child welfare and related social services in cases related to children and families from an ethnic minority background. The purpose of this systematic mapping review is to classify and describe research about link (...) workers working in the field of child welfare and related social services in cases related to children and families from an ethnic minority background. Get alerts about changes Order Download: Key message The purpose of this systematic mapping review is to classify and describe research about link workers working in the field of child welfare and related social services in cases related to children and families from an ethnic minority background. Link workers aim to aid communication and understanding

2021 Norwegian Institute of Public Health

14. SSRI antidepressants and pregnancy: long-term neuropsychiatric disorders in exposed children?

 |   |   |   |  Spotlight SSRI antidepressants and pregnancy: long-term neuropsychiatric disorders in exposed children? FEATURED REVIEW Data available in 2017 suggested that in utero exposure to SSRI antidepressants increases the risk of autism. Do we have a clearer idea in 2020 of the long-term neuropsychiatric harms to the unborn child posed by the use of SSRI antidepressants during pregnancy? Full review (3 pages) available for download by subscribers. Abstract (...) SSRI antidepressants and pregnancy: long-term neuropsychiatric disorders in exposed children? Prescrire IN ENGLISH - Spotlight ''SSRI antidepressants and pregnancy: long-term neuropsychiatric disorders in exposed children?'', 1 January 2021 {1} {1} {1} | | > > > SSRI antidepressants and pregnancy: long-term neuropsychiatric disorders in exposed children? Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   | 

2021 Prescrire

15. Dasatinib (Sprycel and other brands) in children with acute lymphoblastic leukaemia

Dasatinib (Sprycel and other brands) in children with acute lymphoblastic leukaemia Prescrire IN ENGLISH - Spotlight ''In the January issue of Prescrire International: Dasatinib (Sprycel° and other brands) in children with acute lymphoblastic leukaemia'', 1 January 2021 {1} {1} {1} | | > > > In the January issue of Prescrire International: Dasatinib (Sprycel° and other brands) in children with acute lymphoblastic leukaemia Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most (...) recent :  |   |   |   |   |   |   |   |   |  Spotlight In the January issue of Prescrire International: Dasatinib (Sprycel° and other brands) in children with acute lymphoblastic leukaemia FREE DOWNLOAD Dasatinib has been granted marketing authorisation in the European Union as first-line therapy added to chemotherapy for children with Philadelphia chromosome-positive acute lymphoblastic leukaemia. Full text available for free

2021 Prescrire

16. Clinical Practice Guideline for the Management of Communication and Swallowing in Children Diagnosed with Childhood Brain Tumour or Leukaemia

injury Share The NeuroKids Research Laboratory aims to improve the quality of life and communication of children surviving major childhood cancer and acquired brain injury. About We bring together a team of speech pathology experts to conduct a range of clinical research into medical paediatric speech pathology, with the aim of improving the quality of life and communication of children surviving major childhood cancer and acquired brain injury. Our work Clinical Practice Guidelines (...) for the Management of Communication and Swallowing in Children diagnosed with Childhood Brain Tumour or Leukaemia (CBTL). Child survivors of brain cancer and leukaemia - the top two most common childhood cancers in Australia and developed countries worldwide - often face a new challenge during and after their cancer treatment is completed. The (pdf, 6.4mb) has been developed to assist health professionals and patient consumers (parents of children with CBTL, survivors of CBTL) to provide and advocate

2021 Clinical Practice Guidelines Portal

17. Reassessing the Use of Proton Pump Inhibitors and Histamine-2 Antagonists in Critically Ill Children: A Systematic Review and Meta-Analysis

and Children's Hospital, Singapore. 5 Duke-NUS Medical School, Singapore; Children's Intensive Care Unit, KK Women's and Children's Hospital, Singapore. PMID: 32916144 DOI: Item in Clipboard Reassessing the Use of Proton Pump Inhibitors and Histamine-2 Antagonists in Critically Ill Children: A Systematic Review and Meta-Analysis Dominic Wen Jie Yao et al. J Pediatr . 2021 Jan . Show details Display options Display options Format J Pediatr Actions . 2021 Jan;228:164-176.e7. doi: 10.1016/j.jpeds.2020.09.011 (...) Reassessing the Use of Proton Pump Inhibitors and Histamine-2 Antagonists in Critically Ill Children: A Systematic Review and Meta-Analysis Reassessing the Use of Proton Pump Inhibitors and Histamine-2 Antagonists in Critically Ill Children: A Systematic Review and Meta-Analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID

2021 EvidenceUpdates

18. The long-term effect of prenatal progesterone treatment on child development, behaviour and health: a systematic review Full Text available with Trip Pro

, The Netherlands. 4 Department of Paediatric Endocrinology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands. PMID: 33112462 DOI: Item in Clipboard Review The long-term effect of prenatal progesterone treatment on child development, behaviour and health: a systematic review N E Simons et al. BJOG . 2020 . Show details Display options Display options Format BJOG Actions . 2020 Oct 28. doi: 10.1111/1471-0528.16582. Online ahead of print. Authors , , , , , , , , Affiliations 1 Department (...) of Obstetrics, Amsterdam Reproduction and Development Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. 2 Medical Library, Research Support, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. 3 Department of Epidemiology and Data Science, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. 4 Department of Paediatric Endocrinology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands. PMID: 33112462 DOI: Item in Clipboard

2021 EvidenceUpdates

19. A clinical prediction score for transient versus persistent childhood immune thrombocytopenia Full Text available with Trip Pro

persistent childhood immune thrombocytopenia , , , , , , , , , , , Affiliations Expand Affiliations 1 Department of Experimental Immunohematology, Sanquin Research, Amsterdam, the Netherlands. 2 Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. 3 Pediatric and Adolescent Health, Division for Oncology and Hematology, Aarhus University Hospital, Aarhus, Denmark. 4 Department of Pediatric Hematology, University Medical Center Utrecht, Utrecht, the Netherlands. 5 (...) serve as a useful tool for clinicians to individualize patient care. ABSTRACT: Background Childhood immune thrombocytopenia (ITP) is an autoimmune bleeding disorder. The prognosis (transient, persistent, or chronic ITP) remains difficult to predict. The morbidity is most pronounced in children with persistent and chronic ITP. Clinical characteristics are associated with ITP outcomes, but there are no validated multivariate prediction models. Objective Development and external validatation

2021 EvidenceUpdates

20. AARC Clinical Practice Guideline: Management of Pediatric Patients with Tracheostomy in the Acute Care Setting

disease). There are several clinical considerations that impact outcomes of infants and children requiring a tracheostomy. Most are medically complex and have underlying medical conditions that require a variety of equipment such as a feeding pump, portable mechanical ventilator, and mobilization device used in the home or alternate care setting. Assessment of tracheostomy tube size, as well as airway patency and function, are required as the child grows to assure individualized goals for clinical use (...) developmental milestones, minimizing the length of stay (LOS) in intensive care, and reducing hospital readmissions in hospitalized infants and children requiring a tracheostomy. This clinical practice guideline was developed from a systematic review that centered on the following questions relevant to the management of pediatric patients hospitalized with the need for a surgical airway: Does the use of a cuffed tracheostomy tube compared to an uncuffed tube reduce device-associated complications

2021 American Association for Respiratory Care