Latest & greatest articles for knee osteoarthritis

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Top results for knee osteoarthritis

141. 45-day mortality after 467 779 knee replacements for osteoarthritis from the National Joint Registry for England and Wales: an observational study. (Abstract)

45-day mortality after 467 779 knee replacements for osteoarthritis from the National Joint Registry for England and Wales: an observational study. Understanding the risk factors for early death after knee replacement could help to reduce the risk of mortality after this procedure. We assessed secular trends in death within 45 days of knee replacement for osteoarthritis in England and Wales, with the aim of investigating whether any change that we recorded could be explained by alterations (...) in modifiable perioperative factors.We took data for knee replacements done for osteoarthritis in England and Wales between April 1, 2003, and Dec 31, 2011, from the National Joint Registry for England and Wales. Patient identifiers were used to link these data to the national mortality database and the Hospital Episode Statistics database to obtain details of death, sociodemographics, and comorbidity. We assessed mortality within 45 days by Kaplan-Meier analysis and assessed the role of patient

2014 Lancet

142. Prolotherapy: A nontraditional approach to knee osteoarthritis

for patients with knee osteoarthritis (OA) that does not respond to conventional therapies. URI Part of Citation Journal of Family Practice, 63(4) 2014: 206-208 Rights OpenAccess. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. Collections hosted by hosted by (...) Prolotherapy: A nontraditional approach to knee osteoarthritis Prolotherapy: A nontraditional approach to knee osteoarthritis Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Prolotherapy: A nontraditional approach to knee osteoarthritis View/ Open Date 2014-04 Format Metadata Abstract Recommend prolotherapy

2014 PURLS

143. Osteoarthritis of the knee: avoid intra-articular hyaluronic acid injections

Osteoarthritis of the knee: avoid intra-articular hyaluronic acid injections Prescrire IN ENGLISH - Spotlight ''Osteoarthritis of the knee: avoid intra-articular hyaluronic acid injections '', 1 October 2013 {1} {1} {1} | | > > > Osteoarthritis of the knee: avoid intra-articular hyaluronic acid injections Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  (...) Spotlight Osteoarthritis of the knee: avoid intra-articular hyaluronic acid injections At best, intra-articular hyaluronic acid injections give modest relief to patients suffering knee osteoarthritis pain, at the price of local reactions and sometimes severe adverse effects. In patients suffering knee osteoarthritis pain, above all treatment involves physical exercises and analgesics, chiefly paracetamol. Intra-articular hyaluronic acid injections are sometimes offered, but there is no proof

2014 Prescrire

144. Viscosupplementation for the Treatment of Osteoarthritis of the Knee

trials were placed in the appendix and non- randomized studies were not included. OVERALL SUMMARY OF FINDINGS Of the nine systematic reviews (SR) identified, 1-9 five SRs 2,4-5,8-9 indicated some benefit regarding the use of intra-articular hyaluronic acid (IAHA) for the treatment of knee osteoarthritis (OA), whereas the other four SRs 1,3,6-7 did not identify any benefit. In the SRs identifying benefits, IAHA was noted to be most efficacious around eight weeks. 4,8 Prolonged effects of IAHA were (...) ? Includes evidence published from 2005-2007 ? Rec grades: A, B, C, D ? Algorithms provided ? There is some evidence that IAHA may provide some benefit for knee OA ? Algorithm: IAHA for knee OA for patients with moderate- severe persistent symptoms in whom mild- moderate strategies have ? Literature search not designed to identify safety trials; thus this guideline does not provide full safety or usage information on drug Viscosupplementation for the Treatment of Osteoarthritis of the Knee 4 Table 1

2014 Canadian Agency for Drugs and Technologies in Health - Rapid Review

145. Worsening of pain and function over 5 years in individuals with 'early' OA is related to structural damage: data from the Osteoarthritis Initiative and CHECK (Cohort Hip & Cohort Knee) study (Abstract)

Worsening of pain and function over 5 years in individuals with 'early' OA is related to structural damage: data from the Osteoarthritis Initiative and CHECK (Cohort Hip & Cohort Knee) study To analyse the relation of joint damage on evolution of pain and physical functioning in two different cohorts of early phase of osteoarthritis (OA): Osteoarthritis Initiative (OAI) and Cohort Hip & Cohort Knee study (CHECK).Longitudinal data of 4-5 years follow-up (= medium term) of CHECK study and OAI (...) were used. The Western Ontario and McMaster Universities of Osteoarthritis Index (WOMAC) was used to measure pain and physical functioning. For comparison with CHECK a subgroup of the OAI Incidence cohort was selected, Generalised estimating equations were used and all models were adjusted for gender, Body Mass Index, age, amount of working hours, racial background and hip pain at baseline. Finally, an interaction term was added to assess a possible differential effect of radiological progression

2014 EvidenceUpdates

146. Intra-articular use of hyaluronic acid in the treatment of knee osteoarthritis

the likelihood of requiring joint replacement. Most Clinical Practice Guidelines and Health Sponsors consulted agree to cover HA for knee OA which has not responded to non-pharmacological and pharmacological treatments. They do not mention if its use is covered as single or repeated doses. More studies assessing the evolution of single and repeated doses at a longer term are needed to reach better conclusions. Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Hyaluronic Acids (...) Intra-articular use of hyaluronic acid in the treatment of knee osteoarthritis Acido hialurónico intra-articular para artrosis de rodilla [Intra-articular use of hyaluronic acid in the treatment of knee osteoarthritis] Acido hialurónico intra-articular para artrosis de rodilla [Intra-articular use of hyaluronic acid in the treatment of knee osteoarthritis] Pichon Riviere A, Augustovski F, Garcia Marti S, Alcaraz A, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Ciapponi A Record Status

2014 Health Technology Assessment (HTA) Database.

147. Options for managing hips or knee osteoarthritis

version of this Decision Box by . Osteoarthritis (OA) is condition where joint tissue breaks down causing joint pain , stiffness and swelling . It is most common in the knee, hip and hand and it worsens over time. There is no cure for progressive joint damage caused by OA but its symptoms can be managed and quality of life improved. Individuals with clinical symptoms or a diagnosis of OA. When choosing treatment, one should consider treatment costs, the severity of symptoms and an individual’s risk (...) for potentially adverse events. The following treatment options are presented from least to most invasive: Less invasive More invasive Medially wedged insoles Muscle strengthening, aerobic exercises and weight loss for overweight individuals Glucosamine Acetaminophen Acupuncture Oral or topical NSAID therapy Opioid therapy Corticosteroid injection (knee OA) Referral for joint replacement surgery There are pros and cons to each option: PROS : Depending on the option, more or less people have a chance

2014 Cancer Council Australia

148. Systematic review: Review: exercise interventions improve pain and function in people with knee osteoarthritis compared with no exercise

nursing Systematic review Review: exercise interventions improve pain and function in people with knee osteoarthritis compared with no exercise Kim Bennell 1 , Fiona Dobson 2 Statistics from Altmetric.com Commentary on: Uthman OA , van der Windt DA , Jordan JL , et al . Exercise for lower limb osteoarthritis: systematic review incorporating trial sequential analysis and network meta-analysis . Implications for practice and research Conclusive evidence has established the overall benefits of exercise (...) Systematic review: Review: exercise interventions improve pain and function in people with knee osteoarthritis compared with no exercise Review: exercise interventions improve pain and function in people with knee osteoarthritis compared with no exercise | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log

2014 Evidence-Based Nursing

149. The Non-Surgical Management of Hip & Knee Osteoarthritis (OA)

Summary According to the Centers for Disease Control and Prevention (CDC), 13.9 percent of adults age 25 years and older and 33.6 percent of adults age 65 years and older are affected by osteoarthritis (OA). Arthritis appears to be a significant burden among Veterans of the United States (US) Armed Forces. [1] Research suggests that military service-related overuse and injuries may be a contributing factor for the increased risk of developing OA. One study examined the incidence of OA among active (...) of other joints outside the hip or knee expands the differential diagnosis beyond OA. A2. Plain Radiography Background Radiography can be useful in confirming a suspect diagnosis of OA and may eliminate other potential diagnoses from consideration. Recommendation 2. Clinicians may use plain radiography to confirm the clinical diagnosis of hip and knee osteoarthritis. [C] Discussion In adults with non-traumatic knee pain, the consensus of the working group is to obtain a weight- bearing anterior

2014 VA/DoD Clinical Practice Guidelines

150. No Difference Between Intra-Articular Injection of Hyaluronic Acid and Placebo for Mild to Moderate Knee Osteoarthritis: A Randomized, Controlled, Double-Blind Trial (Abstract)

No Difference Between Intra-Articular Injection of Hyaluronic Acid and Placebo for Mild to Moderate Knee Osteoarthritis: A Randomized, Controlled, Double-Blind Trial The main goal of our study was to examine the effectiveness and safety of Fermathron plus, a specific brand of hyaluronic acid (HA), in patients with mild to moderate knee osteoarthritis. In a randomized, controlled, double-blind trial, 196 patients with symptomatic knee osteoarthritis (mean age ± SD, 59.4 ± 9.9 years, Kellgren

2014 EvidenceUpdates Controlled trial quality: predicted high

151. Platelet-rich plasma injections for osteoarthritis of the knee (IPG491)

Platelet-rich plasma injections for osteoarthritis of the knee (IPG491) Platelet-rich plasma injections for osteoarthritis of the knee | Guidance | NICE Platelet-rich plasma injections for osteoarthritis of the knee Interventional procedures guidance [IPG491] Published date: May 2014 Guidance This guidance has been updated and replaced by . Explore © NICE [year]. All rights reserved. Subject to .

2014 National Institute for Health and Clinical Excellence - Interventional Procedures

152. Preoperative physical therapy for severe osteoarthritis of the knee

Publication. 2014 Authors' objectives Physical therapy may be beneficial both before and after joint replacement surgery in patients with severe osteoarthritis (OA). In general, the goal of physical therapy in patients with OA is to increase function and physical activity despite pain and stiffness. Perioperative goals include faster recovery time, shorter hospital length of stay (LOS), and increased range of motion (ROM) and function. Final publication URL The report may be purchased from: Indexing (...) Status Subject indexing assigned by CRD MeSH Activities of Daily Living; Adults; Arthroplasty, Replacement, Knee; Exercise Therapy; Knee Joint; Osteoarthritis, Knee; Pain; Physical Therapy Modalities; Preoperative Care; Range of Motion, Articular; Recovery of Function; Treatment Outcome Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence HAYES, Inc., 157 S. Broad Street, Suite 200, Lansdale, PA 19446

2014 Health Technology Assessment (HTA) Database.

153. Does Running Cause Knee Osteoarthritis?

of as a disease of “wear and tear” on the joints. Is running a risk factor for developing osteoarthritis? If so, is the damage worse for marathon runners? Maybe we should be advising our patients to stick to water aerobics. Approximately OA is a degenerative joint disease characterized by articular cartilage failure, although all structures of the joint are involved in the pathologic process. Risks for developing osteoarthritis include systemic factors (age, female gender, genetic susceptibility), intrinsic (...) on the development of knee osteoarthritis. Felson et al. published a longitudinal study of the Framinghmam Offspring cohort to evaluate the long-term A total of 1,279 subjects were included with a mean age at baseline of 53 years. Most reported walking for exercise. Subjects were asked about their knee pain and anteroposterior and lateral knee radiographs were obtained. Nine years later, subjects were reexamined for osteoarthritis. The primary outcomes of the study included incident radiographic OA, symptomatic

2013 Clinical Correlations

154. Efficacy and safety of tanezumab added on to diclofenac sustained release in patients with knee or hip osteoarthritis: a double-blind, placebo-controlled, parallel-group, multicentre phase III randomised clinical trial (Abstract)

with hip or knee osteoarthritis (OA) pain.Patients (N=604) with moderate to severe knee or hip OA tolerating stable DSR were randomised and treated with DSR 75 mg twice daily combined with intravenous tanezumab 10, 5 or 2.5 mg or placebo at weeks 0, 8 and 16. Co-primary efficacy endpoints (Western Ontario and McMaster Universities OA Index (WOMAC) Pain and Physical Function subscales and patient's global assessment of OA) were assessed at week 16.All co-primary endpoints were significantly improved (...) Efficacy and safety of tanezumab added on to diclofenac sustained release in patients with knee or hip osteoarthritis: a double-blind, placebo-controlled, parallel-group, multicentre phase III randomised clinical trial Tanezumab, a monoclonal antibody, inhibits nerve growth factor and reduces chronic pain. This randomised, double-blind, controlled multicentre study was conducted to evaluate the efficacy and safety of tanezumab added to oral diclofenac sustained release (DSR) in patients

2013 EvidenceUpdates Controlled trial quality: predicted high

155. Meniscectomy in Patients with Knee Osteoarthritis and a Meniscal Tear? (Abstract)

Meniscectomy in Patients with Knee Osteoarthritis and a Meniscal Tear? 23506467 2013 05 21 2018 12 02 1533-4406 368 18 2013 May 02 The New England journal of medicine N. Engl. J. Med. Meniscectomy in patients with knee osteoarthritis and a meniscal tear? 1740-1 10.1056/NEJMe1302696 Buchbinder Rachelle R eng Editorial Comment 2013 03 18 United States N Engl J Med 0255562 0028-4793 AIM IM N Engl J Med. 2013 May 2;368(18):1675-84 23506518 Female Humans Male Osteoarthritis, Knee surgery therapy

2013 NEJM

156. Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial Full Text available with Trip Pro

Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial Strontium ranelate is currently used for osteoporosis. The international, double-blind, randomised, placebo-controlled Strontium ranelate Efficacy in Knee OsteoarthrItis triAl evaluated its effect on radiological progression of knee osteoarthritis.Patients with knee osteoarthritis (Kellgren and Lawrence grade 2 or 3, and joint space width (JSW) 2.5-5 (...) mm) were randomly allocated to strontium ranelate 1 g/day (n=558), 2 g/day (n=566) or placebo (n=559). The primary endpoint was radiographical change in JSW (medial tibiofemoral compartment) over 3 years versus placebo. Secondary endpoints included radiological progression, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, and knee pain. The trial is registered (ISRCTN41323372).The intention-to-treat population included 1371 patients. Treatment with strontium ranelate

2013 EvidenceUpdates Controlled trial quality: predicted high

157. A randomized controlled trial on the efficacy of intermittent and continuous traction for patients with knee osteoarthritis (Abstract)

of motion values (P=0.300).Joint traction was found to be beneficial for the improvement of pain and physical function loss related to knee osteoarthritis. (...) A randomized controlled trial on the efficacy of intermittent and continuous traction for patients with knee osteoarthritis To investigate the efficacy of intermittent and continuous traction in the treatment of knee osteoarthritis.A randomized, controlled, observer-blind seven-week trial.Hospital-based outpatient practice.Ninety-eight patients with stage 3 knee osteoarthritis according to Kellgren-Lawrence radiological rating scale.All 98 patients were randomly assigned to three treatment

2013 EvidenceUpdates Controlled trial quality: uncertain

158. Osteoarthritis of the Knee

Osteoarthritis of the Knee TREATMENT OF OSTEOARTHRITIS OF THE KNEE EVIDENCE-BASED GUIDELINE 2 ND EDITION Adopted by the American Academy of Orthopaedic Surgeons Board of Directors May 18, 2013 i Disclaimer This clinical practice guideline was developed by an AAOS work group comprised of volunteer physicians and interdisciplinary clinicians as well as staff researchers with expertise in systematic reviews and statistical methods used to evaluate empirical evidence. It is an educational tool (...) Peer Review 26 Public Comment 27 The AAOS Guideline Approval Process 28 Revision Plans 28 Guideline Dissemination Plans 28 AAOS Clinical Guideline on Treating Osteoarthritis of the Knee 31 Guideline Recommendations 31 Recommendation 1 31 Rationale 31 Supporting Evidence 32 Quality 32 Applicability 34 Final Strength of Evidence 35 Results 46 Evidence Tables and Figures 61 Quality and Applicability 61 Findings 98 Recommendation 2 138 Rationale 138 Supporting Evidence 138 Quality 138 Applicability 139

2013 American Academy of Orthopaedic Surgeons

159. Aquatic exercise for knee and hip osteoarthritis

Media Releases 2015 Media Releases 2014 Media Releases 2013 Media Releases 2012 Media Releases Search Aquatic exercise for knee and hip osteoarthritis Aquatic exercise for knee and hip osteoarthritis Introduction Warm-water therapy is one of the oldest recorded treatments, with effects lasting well beyond the period of immersion. Intervention Physical exercise while immersed in water (typically 32–36°C). Indication People with osteoarthritis (OA) of the knee or hip with the aim of reducing pain (...) Aquatic exercise for knee and hip osteoarthritis RACGP - Aquatic exercise for knee and hip osteoarthritis Search Become a student member today for free and be part of the RACGP community A career in general practice Starting the GP journey Enrolments for the 2019.1 OSCE FRACGP exams closing 29 March 2019 Fellowship FRACGP exams Research Practice Experience Program is a self-directed education program designed to support non vocationally registered doctors on their pathway to RACGP Fellowship

2013 Handbook of Non-Drug interventions (HANDI)

160. Systematic review with meta-analysis: Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS Full Text available with Trip Pro

Systematic review with meta-analysis: Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie (...) relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS Article Text Therapeutics Systematic review with meta-analysis Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS Andrew Östör , Pippa A Watson Statistics from Altmetric.com Commentary on: Derry S , Moore RA , Rabbie R . Topical NSAIDs for chronic musculoskeletal pain in adults

2013 Evidence-Based Medicine