Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4)
Latest & greatest articles for low back pain
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on low back pain or other clinical topics then use Trip today.
This page lists the very latest high quality evidence on low back pain and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.
What is Trip?
Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.
Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.
As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.
For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via firstname.lastname@example.org
A systematic review of the role of inflammatory biomarkers in acute, subacute and chronic non-specific lowbackpain. Lowbackpain (LBP) is one of the greatest contributors to disability in the world and there is growing interest on the role of biomarkers in LBP. To purpose of this review was to analyze available evidence on the relationship between inflammatory biomarkers, clinical presentation, and outcomes in patients with acute, subacute and chronic non-specific lowbackpain (NSLBP (...) in this review. All results assessed using the modified GRADE demonstrated low to very low quality evidence given the small number of studies and small sample. Three studies examined C-reactive protein (CRP), one of which found significantly higher CRP levels in an acute NSLBP group than in controls and an association between high pain intensity and elevated CRP. Three studies examined tumor necrosis factor alpha (TNF-α), two of which found elevated TNF-α in chronic NSLBP participants compared to controls
Do patients with chronic low-backpain experience a loss of health-related quality of life? A protocol for a systematic review and meta-analysis. Health-related quality of life in chronic lowbackpain (LBP) is an important issue since various individual factors such as perceived loss of autonomy, inability to continue daily life and anxiety can contribute to maintenance or deterioration of this condition. Health-related quality of life is also important because it can predict the probability
On "Short-Term Effect of Kinesiotaping on Chronic Nonspecific LowBackPain and Disability: A Meta-Analysis of Randomized Controlled Trials." Lin S, Zhu, B. Phys Ther. 2020;100:238-254. 32157311 2020 03 11 1538-6724 2020 Mar 11 Physical therapy Phys Ther On "Short-Term Effect of Kinesiotaping on Chronic Nonspecific LowBackPain and Disability: A Meta-Analysis of Randomized Controlled Trials." Lin S, Zhu, B. Phys Ther. 2020;100:238-254. pzaa037 10.1093/ptj/pzaa037 Saueressig Tobias T
Systematic Review of Decision Analytic Modelling in Economic Evaluations of LowBackPain and Sciatica. Lowbackpain (LBP) and sciatica place significant burden on individuals and healthcare systems, with societal costs alone likely to be in excess of £15 billion. Two recent systematic reviews for LBP and sciatica identified a shortage of modelling studies in both conditions.The aim of this systematic review was to document existing model-based economic evaluations for the treatment
Expression of concern: Which specific modes of exercise training are most effective for treating lowbackpain? Network meta-analysis. 32139370 2020 03 09 1473-0480 2020 03 05 British journal of sports medicine Br J Sports Med Expression of concern: Which specific modes of exercise training are most effective for treating lowbackpain? Network meta-analysis. bjsports-2019-100886eoc1 10.1136/bjsports-2019-100886eoc1 eng Journal Article Expression of Concern 2020 03 05 England Br J Sports Med
The natural course of lowbackpain from childhood to young adulthood - a systematic review. Taking the natural course of recurrent and fluctuating lowbackpain (LBP) seen in longitudinal studies of adults into consideration, the aetiology and development of LBP in children and adolescents also needs to be reflected in a long-term course. Therefore, a systematic critical literature review was undertaken to assess the natural course of LBP in the general population from childhood through (...) adolescence to young adulthood.A systematic literature search was conducted in MEDLINE, EMBASE, CINAHL and PsycINFO with synonyms of search terms for 1) lowbackpain; 2) natural course; 3) cohort study and 4) children. Records in English, German, French, Danish, Swedish, and Norwegian were included. To assess the methodological quality of the studies, the NIH quality assessment checklist for cohort studies was adapted and risk of bias was assessed on a study level. Two authors independently reviewed
Can We Trust the Literature on Risk Factors and Triggers for LowBackPain? A Systematic Review of a Sample of Contemporary Literature. Risk factors (RFs) for the "disease" of lowbackpain (LBP) are probably different from the triggers of new episodes of LBP. Investigating RFs for the onset of the "disease" and the triggers of LBP is problematic if researchers fail to discern the different types of pain-free status of participants at and before baseline. There is a difference between never (...) having had LBP and having been pain-free for a certain period only. In this review, we assessed the dependability of contemporary literature on RFs and triggers of LBP, in relation to the "disease" and the episodes, respectively.A literature search from 2010 until 2017 was performed. Information on the definitions of LBP, potential RFs/triggers, and study design was extracted. Studies were reclassified based on the type of LBP concerning the "disease," episode, or mixed/unclear/chronic. RFs
The association between headache and lowbackpain: a systematic review. To systematically review studies quantifying the association between primary chronic headaches and persistent lowbackpain (LBP).We searched five electronic databases. We included case-control, cross-sectional and cohort studies that included a headache and backpain free group, reporting on any association between persistent LBP and primary headache disorders. Methodological quality was assessed using Newcastle-Ottawa
Letter in response to: 'Which specific modes of exercise training are most effective for treating lowbackpain? Network meta-analysis' by Owen 32024645 2020 03 09 1473-0480 2020 02 05 British journal of sports medicine Br J Sports Med Letter in response to: 'Which specific modes of exercise training are most effective for treating lowbackpain? Network meta-analysis' by Owen et al . bjsports-2019-101812 10.1136/bjsports-2019-101812 Maher Chris G CG 0000-0002-1628-7857 Sydney School of Public (...) exercise for lowbackpain (the topic of the review we comment upon in this letter) 2019 12 17 2020 2 7 6 0 2020 2 7 6 0 2020 2 7 6 0 aheadofprint 32024645 bjsports-2019-101812 10.1136/bjsports-2019-101812
Gluteus medius muscle function in people with and without lowbackpain: a systematic review. Globally, lowbackpain (LBP) is one of the greatest causes of disability. In people with LBP, dysfunction of muscles such as the gluteus medius have been demonstrated to increase spinal loading and reduce spinal stability. Differences in gluteus medius function have been reported in those with LBP compared to those without, although this has only been reported in individual studies. The aim
The effectiveness of McKenzie method compared to manual therapy for treating chronic lowbackpain: a systematic review. The aim of this study was to evaluate the effectiveness of the McKenzie method compared to manual therapy in the management of patients with chronic lowbackpain (CLBP). Randomised controlled trials evaluating the McKenzie method in treating CLBP in adults compared to manual therapy (MT) were searched in MEDLINE, CINAHL, Cochrane Library, and PEDro. The primary outcomes were (...) pain and disability. Five trials were eligible for inclusion in the review, of which, most had a score of 8 out of 11 on the PEDro scale. At 2-3 months, all studies reported significant improvement in the pain level in the McKenzie group, and more than that in the MT group. At 6 months, significant improvements had occurred in the disability index reported by two trials in the McKenzie group than the MT group. At 12 months follow-up, there were no significant differences in measures of LBP
To Flex or Not to Flex? Is There a Relationship Between Lumbar Spine Flexion During Lifting and LowBackPain? A Systematic Review With Meta-analysis. To evaluate whether lumbar spine flexion during lifting is a risk factor for lowbackpain (LBP) onset/persistence or a differentiator of people with and without LBP.Etiology systematic review with meta-analysis.Database search of ProQuest, CINAHL, MEDLINE, and Embase up to August 21, 2018.We included peer-reviewed articles that investigated (...) flexion than people without LBP (95% CI: -11.2°, -0.9°; P = .02). Most (9/11) studies reported no significant between-group differences in lumbar flexion during lifting. The included studies were of low quality.There was low-quality evidence that greater lumbar spine flexion during lifting was not a risk factor for LBP onset/persistence or a differentiator of people with and without LBP. J Orthop Sports Phys Ther 2020;50(3):121-130. Epub 28 Nov 2019. doi:10.2519/jospt.2020.9218.
Lower limb muscle strength in patients with lowbackpain: a systematic review and meta-analysis. To systematically review the published studies that compare lower limb muscle strength in patients with lowbackpain to matched healthy controls.We searched Medline, SciELO, Cumulative Index to Nursing and Allied Health (CINAHL), and Scopus up until December 2017. Studies comparing lower limb muscle strength in people diagnosed with lowbackpain to healthy control participants were included (...) in the systematic review.14 studies, which included 951 healthy controls and 919 patients with lowbackpain, fulfilled the inclusion criteria. Meta-analysis revealed a lower muscle strength of hip abductor/extensors and knee extensors in patients with lowbackpain in comparison to healthy controls. The average strength of hip abductors (Five studies, SMD=0.7 95% CI: 0.49 to 0.9) and hip extensors (Two studies, SMD=0.93, 95% CI: 0.62 to 1.23) was significantly lower in patients with lowbackpain compared
How Do Physical Therapists Measure Treatment Outcomes in Adults With Chronic LowBackPain? A Systematic Review. There is an increasing recognition of the importance of using a conceptual framework covering the full range of relevant health domains and outcome measures addressed by physical therapy modalities in patients with chronic lowbackpain (CLBP). However, little is known about what outcome domains have been measured and through what measures in physical therapy research.The purpose (...) for adults with CLBP were included.Study characteristics, outcome domains, instruments, and cutoff values were extracted by 2 reviewers. The PROMIS framework was used for domain categorization.One hundred ninety-five studies were included, with 52 outcome domains and 45 cutoff values identified from 182 instruments reported. Only 14 of 195 studies assessed all PROMIS health core areas, while the PROMIS physical health core area was assessed in all included studies. Pain intensity and disability were
The effect of an integrated multidisciplinary rehabilitation programme alternating inpatient interventions with home-based activities for patients with chronic lowbackpain: a randomized controlled trial To compare the effectiveness of an integrated rehabilitation programme with an existing rehabilitation programme in patients with chronic lowback pain.A single-centre, pragmatic, two-arm parallel, randomized controlled trial (1:1 ratio).A rheumatology inpatient rehabilitation centre (...) in Denmark.A total of 165 adults (aged ⩾ 18 years) with chronic lowback pain.An integrated rehabilitation programme comprising an alternation of three weeks of inpatient stay and 12 weeks of home-based activities was compared with an existing rehabilitation programme of four weeks of inpatient stay.Patient-reported outcomes were collected at baseline and at the 26-week follow-up. The primary outcome was back-specific disability (Oswestry Disability Index). Secondary outcomes included pain intensity
[Effectiveness of ozone therapy compared to other therapies for lowbackpain: a systematic review with meta-analysis of randomized clinical trials]. Lowbackpain is a prevalent disease in the adult population, whose quality of life is considerably affected. In order to solve this problem, several therapies have been developed, of which ozone therapy is an example. Our objective in this study was to determine the effectiveness of ozone therapy for lumbar pain relief in adult patients compared (...) to other therapies (steroid and placebo).We used randomized clinical trials to compare the effectiveness of ozone and other therapies for lumbar pain relief in adults (Prospero: CRD42018090807). Two independent reviewers searched the Medline (1966-April/2018), Scopus (2011-May/2018), Lilacs (1982-May/2018), and Embase (1974-March/2018) databases. We use the terms ozone and pain as descriptors. The primary variable was pain relief and the secondary ones were complication, degree of satisfaction, quality
The effect of mechanical traction on lowbackpain in patients with herniated intervertebral disks: a systemic review and meta-analysis. To evaluate the effectiveness of traction in improving lowbackpain, functional outcome, and disk morphology in patients with herniated intervertebral disks.PubMed, Scopus, Embase, and the Cochrane Library were searched from the earliest record to July 2019.We included randomized control trials which (1) involved adult patients with lowbackpain associated (...) with herniated disk confirmed by magnetic resonance imaging or computed tomography, (2) compared lumbar traction to sham or no traction, and (3) provided quantitative measurements of pain and function before and after intervention. Methodological quality was assessed using the physiotherapy evidence database (PEDro) scale and Cochrane risk of bias assessment.Initial searches for literature yielded 3015 non-duplicated records. After exclusion based on the title, abstract, and full-text review, 7 articles
A Meta-Epidemiological Appraisal of the Effects of Interdisciplinary Multimodal Pain Therapy Dosing for Chronic LowBackPain. Using a meta-analysis, meta-regression, and a meta-epidemiological approach, we conducted a systematic review to examine the influence of interdisciplinary multimodal pain therapy (IMPT) dosage on pain, disability, return to work, quality of life, depression, and anxiety in published randomised controlled trials (RCTs) in patients with non-specific chronic lowbackpain (...) . Heterogeneity was quantified with the I2 metric. A total of 47 RCTs were selected. Subgroup meta-analysis showed that there were larger ES for pain and disability in RCTs with long-length, non-daily contact, and low intensity of treatment. Larger ES were also observed for quality of life in RCTs with short-length, non-daily contact, and low intensity treatment. However, these findings were not confirmed by the meta-regression analysis. Likewise, the summary RORs were not significant, indicating
Treatment Efficacy, Clinical Utility, and Cost-Effectiveness of Multidisciplinary Biopsychosocial Rehabilitation Treatments for Persistent LowBackPain: A Systematic Review. Systematic review.To review the current literature on the treatment efficacy, clinical utility, and cost-effectiveness of multidisciplinary biopsychosocial rehabilitation (MBR) for patients suffering from persistent (nonspecific) lower backpain (LBP) in relation to pain intensity, disability, health-related quality (...) the remaining articles dealing with the efficacy, utility, or cost-effectiveness of intensive (more than 25 hours per week) MBR encompassing at least 3 health domains and cognitive behavioral therapy-based psychological education were included.The search retrieved 1199 publications of which 1116 were duplicates or met the exclusion criteria. Seventy of the remaining 83 articles did not meet the inclusion criteria; thus 13 studies were reviewed. All studies reporting changes in pain intensity or disability
Are movement-based classification systems more effective than therapeutic exercise or guideline based care in improving outcomes for patients with chronic lowbackpain? A systematic review. Objectives: The purpose of this systematic review was to determine if movement-based classification (MBC) systems are more effective than therapeutic exercise or guideline-based care (GBC) in improving outcomes in patients with lowbackpain (LBP) based upon randomized clinical trials (RCT) with moderate (...) to high methodological quality and low to moderate risk of bias. Methods: The search strategy was developed by a librarian experienced in systematic review methodology and peer reviewed by a second research librarian. The following databases were searched from their inception to May 17, 2018: PubMed, Embase, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, and the WHO International Clinical Trials Registry Platform. The identified RCTs with a PEDro score of ≥6 were screened