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Latest & greatest articles for osteoarthritis
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on osteoarthritis or other clinical topics then use Trip today.
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Horizon Scanning Research&Intelligence Centre. Horizon Scanning Review. 2016 Authors' conclusions Osteoarthritis is the most common type of arthritis in the UK and leads to painful and stiff joints. Osteoarthritis can affect any joint, but commonly affects knee joints. Daily routine activities can become difficult for patients with osteoarthritis of the knee. There is no cure for osteoarthritis of the knee but there are treatments which help to reduce the pain. In cases where treatment does not work (...) , knee surgery may be offered. Ampion is a new drug for the treatment of osteoarthritis of the knee given as an injection into the affected joint. Some studies have suggested that Ampion may help in reducing knee pain in patients who have osteoarthritis of the knee. If Ampion is licensed for use in the UK, it could be a new treatment option for patients with osteoarthritis of the knee which may improve patient quality of life better than existing treatments. Final publication URL Indexing Status
Feasibility of a Randomized Controlled Trial of Self-Administered Acupressure for Symptom Management in Older Adults with Knee Osteoarthritis. To assess the feasibility of a study to evaluate the efficacy of self-administered acupressure in pain and related symptom management for older people with symptomatic knee osteoarthritis. Feasibility with regard to (1) sample recruitment and retention, (2) treatment fidelity and adherence, and (3) tolerability and adverse events was examined.The study (...) from performing the acupressure. Thirty adverse events were reported; most were related to pre-existing health conditions.It is feasible to conduct a study of self-administered acupressure for symptom management in community-living older adults with knee osteoarthritis, although sample recruitment may be challenging.
Hallux valgus, ankle osteoarthrosis and adult acquired flatfoot deformity: a review of three common foot and ankle pathologies and their treatments The pathogenesis of hallux valgus deformity is multifactorial. Conservative treatment can alleviate pain but is unable to correct the deformity. Surgical treatment must be adapted to the type and severity of the deformity. Success of surgical treatment ranges from 80% to 95%, and complication rates range from 10% to 30%.Ankle osteoarthrosis most (...) commonly occurs as a consequence of trauma. Ankle arthrodesis and total ankle replacement are the most common surgical treatments of end stage ankle osteoarthrosis. Both types of surgery result in similar clinical improvement at midterm; however, gait analysis has demonstrated the superiority of total ankle replacement over arthrodesis. More recently, conservative surgery (extraarticular alignment osteotomies) around the ankle has gained popularity in treating early- to mid-stage ankle
Patient-reported quality indicators for osteoarthritis: a patient and public generated self-report measure for primary care People with osteoarthritis desire high quality care, support and information. However, the quality of care for people with OA in general practice is not routinely collected. Quality Indicators can be used to benefit patients by measuring whether minimum standards of quality care are being met from a patient perspective. The aim of this study was to describe how a Research (...) User Group (RUG) worked alongside researchers to co-produce a set of self-reported quality indicators for people with osteoarthritis when visiting their general practitioner or practice nurse (primary care). These were required in the MOSAICS study, which developed and evaluated a new model of supported self-management of OA to implement the NICE quality standards for OA. This article describes the public involvement in the MOSAICS study. This was 1) the co-development by RUG members
Effect of Vitamin D Supplementation on Tibial Cartilage Volume and Knee Pain Among Patients With Symptomatic Knee Osteoarthritis: A Randomized Clinical Trial. Observational studies suggest that vitamin D supplementation is associated with benefits for knee osteoarthritis, but current trial evidence is contradictory.To compare the effects of vitamin D supplementation vs placebo on knee pain and knee cartilage volume in patients with symptomatic knee osteoarthritis and low vitamin D levels.A (...) multicenter randomized, double-blind, placebo-controlled clinical trial in Tasmania and Victoria, Australia. Participants with symptomatic knee osteoarthritis and low 25-hydroxyvitamin D (12.5-60 nmol/L) were enrolled from June 2010 to December 2011. The trial was completed in December 2013.Participants were randomly assigned to receive monthly treatment with oral vitamin D3 (50,000 IU; n = 209) or an identical placebo (n = 204) for 2 years.Primary outcomes were change in tibial cartilage volume (assessed
function was evaluated in patients with osteoarthritis (OA).Using a randomized study design, 48 sedentary middle-aged and older adults with OA underwent 3 months of either swimming or cycling exercise training. Supervised exercise training was performed for 45 min/day, 3 days/week at 60-70% heart rate reserve for 12 weeks. The Western Ontario and McMaster Universities Arthritis Index was used to measure joint pain, stiffness, and physical limitation.After the exercise interventions, there were (...) Improved Function and Reduced Pain after Swimming and Cycling Training in Patients with OsteoarthritisArthritis and its associated joint pain act as significant barriers for adults attempting to perform land-based physical activity. Swimming can be an ideal form of exercise for patients with arthritis. Yet there is no information on the efficacy of regular swimming exercise involving patients with arthritis. The effect of a swimming exercise intervention on joint pain, stiffness, and physical
Joint sparing treatments in early ankle osteoarthritis: current procedures and future perspectives Ankle osteoarthritis (AOA) is a severe pathology, mostly affecting a post-traumatic young population. Arthroscopic debridement, arthrodiastasis, osteotomy are the current joint sparing procedures, but, in the available studies, controversial results were achieved, with better outcomes in case of limited degeneration. Only osteotomy in case of malalignment is universally accepted as a joint sparing (...) procedure in case of partial AOA. Recently, the biological mechanism of osteoarthritis has been intensively studied: it is a whole joint pathology, affecting cartilage, bone and synovial membrane. In particular, the first stage is characterized by a reversible catabolic activity with a state of chondropenia. Thus, biological procedures for early AOA were proposed in order to delay or to avoid end stage procedures. Mesenchymal stem cells (MSCs) may be a good solution to prevent or reverse degeneration
The Incremental Effects of Manual Therapy or Booster Sessions in Addition to Exercise Therapy for Knee Osteoarthritis: A Randomized Clinical Trial A factorial randomized controlled trial.To investigate the addition of manual therapy to exercise therapy for the reduction of pain and increase of physical function in people with knee osteoarthritis (OA), and whether "booster sessions" compared to consecutive sessions may improve outcomes.The benefits of providing manual therapy in addition (...) to exercise therapy, or of distributing treatment sessions over time using periodic booster sessions, in people with knee OA are not well established.All participants had knee OA and were provided 12 sessions of multimodal exercise therapy supervised by a physical therapist. Participants were randomly allocated to 1 of 4 groups: exercise therapy in consecutive sessions, exercise therapy distributed over a year using booster sessions, exercise therapy plus manual therapy without booster sessions
is limited by adverse effects such as increased cardiovascular events, gastrointestinal (GI) perforation, ulceration, and bleeding, and renal impairment. The risks of these complications increase with age, drug-drug and drug-disease interactions, and probably duration of use. These risks are especially important concerning the typically older population affected by osteoarthritis (OA) who often have comorbidities and take multiple medications. Alternative therapies to reduce these risks are limited. All (...) and Quality (AHRQ); 2016 Jun. [cited YYYY Mon DD]. Available: http://www.guideline.gov. A direct comparison of recommendations presented in the above guidelines for nonsurgical management of osteoarthritis (OA) of the knee is provided. The AAOS guideline provides recommendations for surgical interventions that are less invasive than knee replacement, which are beyond the scope of this synthesis. The VA/DoD guideline addresses OA of the hip, which is also beyond the scope of this synthesis (recommendations
Media Releases 2013 Media Releases 2012 Media Releases Search Knee taping for osteoarthritis Knee taping for osteoarthritis Introduction Knee osteoarthritis is the most common cause of knee pain in people older than 50. Intervention Application of strong, adhesive tape or strapping aiming to unload painful soft tissues. Indication Chronic pain related to knee osteoarthritis (OA). Malalignment of the patella, with abnormal distribution of force on the lateral facet, is thought to contribute to pain (...) in knee osteoarthritis. Taping increases patellofemoral contact area, decreasing joint stress and thereby reducing pain. Taping is a very effective pain-relieving strategy and can assist participation in other strongly recommended therapies for knee osteoarthritis, such as cardiovascular and resistance land-based and aquatic exercises. Precautions A physiotherapist experienced in assessment and taping techniques should show the patient how to apply the tape: Precise placement of tape is needed
Releases 2016 Media Releases 2015 Media Releases 2014 Media Releases 2013 Media Releases 2012 Media Releases Search Splints for the reduction of pain from hand osteoarthritis Splints for the reduction of pain from hand osteoarthritis Introduction Hand OA mainly affects women and often starts around the time of menopause. Intervention Prefabricated or custom-made splints. Indication Patients with mild to moderate pain from OA of the first carpometacarpal joint (CMC-1) at the base of the thumb. Other (...) hand joints commonly affected by OA are the distal interphalangeal joints and the proximal interphalangeal joints; however, the majority of evidence relates to splints for OA at the base of the thumb. Availability Neoprene prefabricated splints are available from pharmacies, sports stores, mobility equipment centres and online. Neoprene hand splints are priced from around $50. Custom-made splints, usually constructed from thermoplastic material, can be fabricated by hand therapists (occupational
Media Releases 2013 Media Releases 2012 Media Releases Search Walking cane for knee osteoarthritis Walking cane for knee osteoarthritis Introduction Use of a cane is one of a number of non-drug treatments for knee osteoarthritis; which include weight reduction, exercise and taping. Intervention Daily use of a walking cane or stick to decrease the load transmitted through the affected knee(s) and improve pain and function. Indication People with knee osteoarthritis (OA) who have pain and difficulty (...) Walking cane: knee osteoarthritis RACGP - Walking cane for knee osteoarthritis Search Become a student member today for free and be part of the RACGP community A career in general practice Starting the GP journey Enrolments for the 2019.1 OSCE FRACGP exams closing 29 March 2019 Fellowship FRACGP exams Research Practice Experience Program is a self-directed education program designed to support non vocationally registered doctors on their pathway to RACGP Fellowship Fellowship International
Exercise for knee osteoarthritis RACGP - Handbook of Non-Drug Interventions (HANDI) Search Become a student member today for free and be part of the RACGP community A career in general practice Starting the GP journey Enrolments for the 2019.1 OSCE FRACGP exams closing 29 March 2019 Fellowship FRACGP exams Research Practice Experience Program is a self-directed education program designed to support non vocationally registered doctors on their pathway to RACGP Fellowship Fellowship International
of included study First Author, year and type of study Population and setting Intervention or exposure tested Study results Assessment of quality and comments Sibbitt RCT 2009 Undertaken in Finland, 148 subjects 100 had Rheumatoid arthritis (RA) 48 Osteoarthritis (OA) 95% large joints 5% small joints (n=7 patients) Randomised into 2 groups 1.Injection with palpation 2. Ultrasound guided needle placement Outcome = Visual analogue scale. Taken at baseline, during procedure and after 2 weeks Palpation guided (...) Is a clinically guided steroid injection as effective in terms of pain relief and improved function as an ultrasound guided injection for patient with first CMC jointosteoarthritis (OA) Getting Evidence into Clinical Practice: Musculoskeletal Research Facilitation Group (CAT Group) Date: September 2016 CAT Lead: Kay Stevenson and Kirsty Thomson Date CAT completed: Email: firstname.lastname@example.org Date CAT to be reviewed: September 2018 Specific Question: Is a clinically guided steroid
In adult patients immediately post primary total knee replacement (TKR) for osteoarthritis (OA) is group therapy more clinically effective than an individual programme for pain and function? Musculoskeletal Research Facilitation Group (Cat Group) Critically appraised topic and clinical bottom line Date: April 2016 CAT Lead: Mark Buckley Date CAT completed: April 2016 Email: email@example.com Date CAT to be reviewed: April 2018 Specific Question: In adult patients immediately post primary (...) total knee replacement (TKR) for osteoarthritis (OA) is group therapy more clinically effective than an individual programme for pain and function? Clinical bottom line After TKR, group rehabilitation is not more effective than individual rehabilitation. Individual rehabilitation appears similarly effective if undertaken as a package of 2 initial individual face-to-face treatment sessions followed by telephone support for a home exercise programme or as a package of 12 individual treatment sessions
A Combined Patient and Provider Intervention for Management of Osteoarthritis in Veterans: A Randomized Clinical Trial. Management of osteoarthritis requires both medical and behavioral strategies, but some recommended therapies are underused.To examine the effectiveness of a combined patient and provider intervention for improving osteoarthritis outcomes.Cluster randomized clinical trial with assignment to osteoarthritis intervention and usual care groups. (ClinicalTrials.gov: NCT01130740 (...) ).Department of Veterans Affairs Medical Center in Durham, North Carolina.30 providers (clusters) and 300 outpatients with symptomatic hip or knee osteoarthritis.The telephone-based patient intervention focused on weight management, physical activity, and cognitive behavioral pain management. The provider intervention involved delivery of patient-specific osteoarthritis treatment recommendations to primary care providers through the electronic medical record.The primary outcome was total score
of the hip joint, participants reported whether they had hip pain on most days and the location of the pain: anterior, groin, lateral, buttocks, or low back. In the Framingham study, participants with hip pain were also examined for hip pain with internal rotation. The authors analysed the agreement between radiographic hip osteoarthritis and hip pain, and for those with hip pain suggestive of hip osteoarthritis they calculated the sensitivity, specificity, positive predictive value, and negative (...) Association of hip pain with radiographic evidence of hip osteoarthritis: diagnostic test study. Is there concordance between hip pain and radiographic hip osteoarthritis?In this diagnostic test study, pelvic radiographs were assessed for hip osteoarthritis in two cohorts: the Framingham Osteoarthritis Study (community of Framingham, Massachusetts) and the Osteoarthritis Initiative (a multicenter longitudinal cohort study of osteoarthritis in the United States). Using visual representation