Latest & greatest articles for osteoarthritis

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Top results for osteoarthritis

321. Efficacy of Triamcinolone Hexacetonide versus Methylprednisolone Acetate Intraarticular Injections in Knee Osteoarthritis: A Randomized, Double-blinded, 24-week Study (Abstract)

OA and Kellgren-Lawrence grade II or III were randomized to receive 40 mg of IA TH or MA. Evaluations were performed at 4, 12, and 24 weeks. The primary outcome was a change in the patient's assessment of pain by visual analog scale from baseline to Week 4. Secondary outcomes included a global assessment of the disease by patients and physicians, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Lequesne index (LI), and Outcome Measures in Rheumatology Clinical Trials (...) Efficacy of Triamcinolone Hexacetonide versus Methylprednisolone Acetate Intraarticular Injections in Knee Osteoarthritis: A Randomized, Double-blinded, 24-week Study Intraarticular (IA) corticosteroid injections are broadly used in knee osteoarthritis (OA); however, the best corticosteroid agent is not well defined. The aim of the present study was to compare the efficacy of triamcinolone hexacetonide (TH) and methylprednisolone acetate (MA) injections in knee OA.Patients with symptomatic knee

2015 EvidenceUpdates Controlled trial quality: predicted high

322. Joint distraction for knee osteoarthritis without alignment correction

information on the evidence, see the interventional procedure overview. 4.1 A case series of 20 patients with end-stage knee osteoarthritis treated by joint distraction reported significant improvements in Western Ontario and McMaster Universities Arthritis Index (WOMAC) scores (normalised to a 100-point scale for total and subscales; 100 being the best score) of 70% at 1-year follow-up and of 74% at 2-year follow-up (p<0.001 for both improvements from baseline). The individual components of the WOMAC (...) Joint distraction for knee osteoarthritis without alignment correction Joint distr Joint distraction for knee osteoarthritis without action for knee osteoarthritis without alignment correction alignment correction Interventional procedures guidance Published: 23 July 2015 nice.org.uk/guidance/ipg529 Y Y our responsibility our responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare

2015 National Institute for Health and Clinical Excellence - Interventional Procedures

323. Does topical diclofenac relieve osteoarthritis pain?

pain? Evidence-based answer: Yes, at least in the short term. Topical diclofenac, with and without dimethyl sulfoxide (DMSO), modestly improves pain and function scores (by 4%-8%) for as long as 12 weeks in patients with osteoarthritis (OA) of the knee (strength of recommendation [SOR]: A, meta-analyses of multiple randomized controlled trials [RCTs]). Topical diclofenac modestly decreases pain scores in patients with OA of the hand in the short term (by 9% at 6 weeks) but no more than placebo at 8 (...) Does topical diclofenac relieve osteoarthritis pain? Does topical diclofenac relieve osteoarthritis pain? Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Does topical diclofenac relieve osteoarthritis pain? View/ Open Date 2015-02 Contributor Format Metadata Abstract Q: Does topical diclofenac relieve osteoarthritis

2015 Clinical Inquiries

324. Viscosupplementation for Knee Osteoarthritis

(DC): Department of Veterans Affairs, Department of Defense; 2014. [cited 2015 Apr 17]. Available from: http://www.healthquality.va.gov/guidelines/CD/OA/VADoDOAClinicianSummaryFINAL090 214.pdf See: Recommendation 23, page 5 8. American Academy of Orthopaedic Surgeons clinical practice guideline on treatment of osteoarthritis of the knee [Internet]. 2nd ed. Rosemont (IL): American Academy of Orthopaedic Surgeons (AAOS); 2013 May 18. [cited 2015 Apr 17]. Available from: http://www.aaos.org/research (...) /guidelines/TreatmentofOsteoarthritisoftheKneeGuideline.pdf See: Recommendation 9, page 770 9. Work Loss Data Institute. Knee & leg (acute & chronic). Encinitas (CA): Work Loss Data Institute; 2013 Nov 29. Summary available from: http://www.guideline.gov/content.aspx?id=47585 See: Arthritis, ODG Return-To-Work Pathways Viscosupplementation for Knee Osteoarthritis 4 10. Hochberg MC, Altman RD, April KT, Benkhalti M, Guyatt G, McGowan J, et al. American College of Rheumatology 2012 recommendations

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

325. Osteoarthritis: avoid diacerein

Osteoarthritis: avoid diacerein Prescrire IN ENGLISH - Spotlight ''Osteoarthritis: avoid diacerein'', 1 April 2015 {1} {1} {1} | | > > > Osteoarthritis: avoid diacerein Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Osteoarthritis: avoid diacerein Despite an unfavourable harm-benefit balance and demands by the medicines agencies of several EU (...) Member States for diacerein to be withdrawn, the drug is still on the market. Diacerein (Art 50° or other) is a drug used in France for treating the symptoms of osteoarthritis of the hip and the knee. Its efficacy is unproven, and its adverse effects appear disproportionate: gastrointestinal disorders including diarrhoea, bleeding and stomach ulcer, pancreatitis, colitis; skin disorders and hypersensitivity reactions; sometimes fatal hepatobiliary damage. In 2012, the French health products agency

2015 Prescrire

326. A meta-analysis of intervention studies on the effects of self-management in knee osteoarthritis Full Text available with Trip Pro

with an arthritis passport for patients with rheumatoid arthritis", Arthritis Care & Research, Vol. 10, 4, pp. 238-249, 1997. DOI: http://dx.doi.org/10.1002/art.1790100405 S. Y. Park, J. T. Son, D. H. Park, K. H. Lee, J. S. Kim, "Effects of self help program for pain, ADL, exercise self-efficacy and knowledge about arthritis in patients with osteoarthritis", Journal of Rheumatology, Vol. 11, 1, pp. 31-41, 2004. Korean Society of Muscle and Joint Health, Self-help program of osteoarthritis patients, 2014, http (...) in physical activity, joint stiffness, flexibility of the joints in arthritis patients", Journal of Muscle Joint Health, Vol. 14, 1, pp. 26-32, 2007. E. Y. Cheon, "The effects of a self-management program on physical function and quality of life of patients with knee osteoarthritis", Journal of Korean Academy Nursing, Vol. 35, 3, pp. 514-525, 2005. I. O. Lee, M. J. Suh, K. S. Lee, "The effects of follow-up with peer group meetings after self-help program for arthritis patients", Journal of Rheumatology

2015 Journal of the Korea Academia-Industrial cooperation Society

327. Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials Full Text available with Trip Pro

osteoarthritis: estimates from the Global Burden of Disease 2010 study. Hoy D, March L, Brooks P, et al. The global burden of low back pain: estimates from the Global Burden of Disease 2010 study. Hoy D, March L, Woolf A, et al. The global burden of neck pain: estimates from the Global Burden of Disease 2010 study. United States Bone and Joint Initiative. The burden of musculoskeletal diseases in the United States. 3rd ed. American Academy of Orthopaedic Surgeons, 2014. . Bertin P, Becquemont L, Corruble E (...) , CINAHL, Web of Science, LILACS, International Pharmaceutical Abstracts, and Cochrane Central Register of Controlled Trials from inception to 8 December 2014. We used a combination of relevant keywords to construct the search strategy including paracetamol, acetaminophen, back pain, neck pain, osteoarthritis, osteoarthrosis, placebo, randomised, and controlled trial (see appendix 1). One author (GCM) conducted the first screening of potentially relevant records based on titles and abstract, and two

2015 BMJ

328. Osteoarthritis. (Abstract)

Osteoarthritis. Osteoarthritis is a major source of pain, disability, and socioeconomic cost worldwide. The epidemiology of the disorder is complex and multifactorial, with genetic, biological, and biomechanical components. Aetiological factors are also joint specific. Joint replacement is an effective treatment for symptomatic end-stage disease, although functional outcomes can be poor and the lifespan of prostheses is limited. Consequently, the focus is shifting to disease prevention (...) and the treatment of early osteoarthritis. This task is challenging since conventional imaging techniques can detect only quite advanced disease and the relation between pain and structural degeneration is not close. Nevertheless, advances in both imaging and biochemical markers offer potential for diagnosis and as outcome measures for new treatments. Joint-preserving interventions under development include lifestyle modification and pharmaceutical and surgical modalities. Some show potential, but at present

2015 Lancet

329. Effectiveness of a cognitive-behavioural group intervention for knee osteoarthritis pain: A randomized controlled trial (Abstract)

Effectiveness of a cognitive-behavioural group intervention for knee osteoarthritis pain: A randomized controlled trial To assess the effectiveness of a six week cognitive-behavioural group intervention in patients with knee osteoarthritis pain.Single-blinded randomized controlled trial.Primary care providers in a medium-sized city in Finland.A total of 111 participants aged from 35 to 75 with clinical symptoms and radiographic grading (Kellgren-Lawrence 2-4) of knee osteoarthritis were (...) included.In the intervention group, 55 participants attended a cognitive-behavioural training programme for pain management with six weekly group sessions supervised by a psychologist and a physiotherapist. Concurrently, they and the 56 participants of the control group continued in ordinary GP care that was not altered by the study.The primary outcome on three-month and 12-month follow-up was the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis index pain subscale. Secondary outcome

2015 EvidenceUpdates Controlled trial quality: predicted high

330. What Is the Utility of Biomarkers for Assessing the Pathophysiology of Hip Osteoarthritis? A Systematic Review Full Text available with Trip Pro

their clinical use and potential application to prearthritic hip disease. Introduction Osteoarthritis (OA) is one of the most common conditions in medicine, affecting almost 27 million people in the United States alone. In particular, radiographic hip OA is present in approximately one in four individuals older than age 45 years [ ]. The diagnosis of hip OA is made using radiographs and is based on features like narrowing of the femoroacetabular joint space, presence of osteophytes, and subchondral cysts (...) in hip joint diseases. J Rheumatol. 2001;28:341-345. 24. Kelman A, Lui L, Yao W, Krumme A, Nevitt M, Lane NE. Association of higher levels of serum cartilage oligomeric matrix protein and N-telopeptide crosslinks with the development of radiographic hip osteoarthritis in elderly women. Arthritis Rheum. 2006;54:236-243 10.1002/art.21527. 25. Kenanidis E, Potoupnis ME, Papavasiliou KA, Pellios S, Sayegh FE, Petsatodis GE, Karatzas N, Kapetanos GA. The serum levels of receptor activator of nuclear

2015 Clinical Orthopaedics and Related Research®

331. Knee Osteoarthritis

Knee Osteoarthritis 1 Osteoarthritis (OA) of the Knee Management Options Brief Decision Aid There are many different options for the management of osteoarthritis. These can be split into four main groups. It is possible to try combinations of some options: ? Lifestyle changes – increasing exercise, weight loss (if overweight). ? Physical treatments – physiotherapy, shoe insoles, knee supports, walking aids, heat, TENS machine. ? Pain medication – tablets, creams/gels or injections (...) reduce the chance of arthritis worsening? Benefits and Risks of Lifestyle changes Treatment option Benefits Risks/ consequences General exercise (aiming for minimum 2.5 hours a week e.g. 5x30mins). Knee exercises (see physiotherapy). Helps strengthen muscles and joints, to keep you fit, and maintain good range of joint movement. Reduces pain in arthritic joints. Can also help you lose weight. Knee exercise can help you walk further and faster. Knee exercises may protect the joint and slow down

2015 SickKids Reports

332. Joint protection strategies for hand osteoarthritis

(from Arthritis Research UK) about hand OA and its management – managing pain during everyday activities, how to change habits, long-term and short-term goal setting, weekly home programs to practise skills taught, and weekly review of home programs. They were given a workbook which contained key points from each session, photographs demonstrating how to use the joint protection principles while doing daily activities, and weekly activity diaries (see Consumer resources). Patients were also informed (...) about how joint protection fits into broader management of hand OA and joint pain. Source: Dziedzic K, Hammond A et al. Looking after your joints: joint protection for hand osteoarthritis and hand pain – workbook. Keele University and Salford University, 2008, p.11. Tips and challenges Incorporation of strategies into a patient’s daily routine may be improved by encouraging the patient to come up with solutions to their individual problems, using the joint protection strategies. To improve adherence

2015 Handbook of Non-Drug interventions (HANDI)

333. Systematic review with meta-analysis: Paracetamol is ineffective for spinal pain and knee and hip osteoarthritis

Systematic review with meta-analysis: Paracetamol is ineffective for spinal pain and knee and hip osteoarthritis Paracetamol is ineffective for spinal pain and knee and hip osteoarthritis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Paracetamol is ineffective for spinal pain and knee and hip osteoarthritis Article Text Therapeutics/Prevention Systematic review with meta-analysis Paracetamol is ineffective for spinal pain and knee

2015 Evidence-Based Medicine

334. Systematic review with meta analysis: In knee osteoarthritis, pharmacological interventions, with the exception of acetaminophen, significantly improve pain; with intra-articular administration being more effective

Commentary on: Bannuru RR , Schmid CH , Kent DM , et al . Comparative effectiveness of pharmacologic interventions for knee osteoarthritis: a systematic review and network meta-analysis . Context Knee osteoarthritis (OA) is a progressive degenerative disease affecting many individuals worldwide. Owing to high disease burden and increasing healthcare costs, the relative efficacy of different treatment options have been extensively studied. 1 , 2 There have been numerous studies comparing effectiveness (...) Systematic review with meta analysis: In knee osteoarthritis, pharmacological interventions, with the exception of acetaminophen, significantly improve pain; with intra-articular administration being more effective In knee osteoarthritis, pharmacological interventions, with the exception of acetaminophen, significantly improve pain; with intra-articular administration being more effective | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content

2015 Evidence-Based Medicine

335. Pulsed electromagnetic fields in knee osteoarthritis: a double blind, placebo-controlled, randomized clinical trial Full Text available with Trip Pro

Pulsed electromagnetic fields in knee osteoarthritis: a double blind, placebo-controlled, randomized clinical trial This trial aimed to test the effectiveness of a wearable pulsed electromagnetic fields (PEMF) device in the management of pain in knee OA patients.In this randomized [with equal randomization (1:1)], double-blind, placebo-controlled clinical trial, patients with radiographic evidence of knee OA and persistent pain higher than 40 mm on the visual analog scale (VAS) were recruited (...) . The trial consisted of 12 h daily treatment for 1 month in 60 knee OA patients. The primary outcome measure was the reduction in pain intensity, assessed through VAS and WOMAC scores. Secondary outcomes included quality of life assessment through the 36-item Medical Outcomes Study Short-Form version 2 (SF-36 v2), pressure pain threshold (PPT) and changes in intake of NSAIDs/analgesics.Sixty-six patients were included, and 60 completed the study. After 1 month, PEMF induced a significant reduction in VAS

2015 EvidenceUpdates Controlled trial quality: predicted high

336. Systematic review for effectiveness of hyaluronic acid in the treatment of severe degenerative joint disease(DJD) of the knee

. 2015 Authors' objectives The Coverage and Analysis Group at the Centers for Medicare and Medicaid Services (CMS) requested from The Technology Assessment Program (TAP) at the Agency for Healthcare Research and Quality (AHRQ), a review of the evidence that intraarticular injections of hyaluronic acid (HA) in individuals with degenerative joint disease (osteoarthritis [HA]) of the knee improve function and quality of life (QoL) and that they delay or prevent the need for total knee replacement (TKR (...) Systematic review for effectiveness of hyaluronic acid in the treatment of severe degenerative joint disease(DJD) of the knee Systematic review for effectiveness of hyaluronic acid in the treatment of severe degenerative joint disease (DJD) of the knee Systematic review for effectiveness of hyaluronic acid in the treatment of severe degenerative joint disease (DJD) of the knee Newberry SJ, Fitzgerald JD, Maglione MA, O'Hanlon CE, Booth M, Motala A, Timmer M, Shanman R, Shekelle PG Record Status

2015 Health Technology Assessment (HTA) Database.

337. Metal-on-metal hip resurfacing arthroplasty versus total hip replacement for osteoarthritis

Metal-on-metal hip resurfacing arthroplasty versus total hip replacement for osteoarthritis Metal-on-metal hip resurfacing arthroplasty versus total hip replacement for osteoarthritis Metal-on-metal hip resurfacing arthroplasty versus total hip replacement for osteoarthritis HAYES, Inc. Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc.. Metal-on-metal (...) hip resurfacing arthroplasty versus total hip replacement for osteoarthritis. Lansdale: HAYES, Inc.. Directory Publication. 2015 Final publication URL The report may be purchased from: Indexing Status Subject indexing assigned by CRD MeSH Arthroplasty, Replacement, Hip; Humans; Metals; Osteoarthritis Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence HAYES, Inc., 157 S. Broad Street, Suite 200

2015 Health Technology Assessment (HTA) Database.

338. Joint protection and hand exercises for hand osteoarthritis: an economic evaluation comparing methods for the analysis of factorial trials Full Text available with Trip Pro

Joint protection and hand exercises for hand osteoarthritis: an economic evaluation comparing methods for the analysis of factorial trials Evidence regarding the cost-effectiveness of joint protection and hand exercises for the management of hand OA is not well established. The primary aim of this study is to assess the cost-effectiveness (cost-utility) of these management options. In addition, given the absence of consensus regarding the conduct of economic evaluation alongside factorial (...) trials, we compare different analytical methodologies.A trial-based economic evaluation to assess the cost-utility of joint protection only, hand exercises only and joint protection plus hand exercises compared with leaflet and advice was undertaken over a 12 month period from a UK National Health Service perspective. Patient-level mean costs and mean quality-adjusted life years (QALYs) were calculated for each trial arm. Incremental cost-effectiveness ratios (ICERs) were estimated and cost

2015 EvidenceUpdates Controlled trial quality: uncertain

339. Intra-Articular Hyaluronic Acid for Osteoarthritis of the Knee

and Blue Shield Association Medical Advisory Panel made the following judgments about whether the use of intra-articular hyaluronic acid (IAHA) for knee osteoarthritis (OA) meets the Blue Cross and Blue Shield Association Technology Evaluation Center (TEC) criteria. 1. The technology must have final approval from the appropriate governmental regulatory bodies. Seven different formulations of hyaluronic acid products are currently approved for marketing in the United States for intra-articular injection (...) in the knee. All were approved as class III devices via the U.S. Food and Drug Administration's Premarket Application approval process. All 7 devices are indicated for the "treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy, and simple analgesics, e.g., acetaminophen." 2. The scientific evidence must permit conclusions concerning the effect of the technology on health outcomes. Although a large body of evidence

2015 Health Technology Assessment (HTA) Database.

340. The Effect of Exercise Program on Pain and Quality of Life for Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis Full Text available with Trip Pro

://dx.doi.org/10.7326/0003-4819-151-4-200908180-00135 Kang, Y. H. (2008). Encyclopedia of life science. Seoul, Korea: Academy Pub. Kim, J. K., & Roh, S. K. (2009). Effect of Nordic walking and aquatic exercise on oxidative stress and pain in women with degenerative arthritis. Exercise Science, 18 (4), 549-558. Kim, Y. J., Seo N. S., Lim, Y. N., Kim, H, S., Kim, Y. S., & Kim, S. J. (2012). Effects of taekwondo exercise program in women with osteoarthritis. Journal of Muscle and Joint Health, 19 (2), 210-222 (...) in patients with osteoarthritis. Journal of Muscle and Joint Health, 16 (1), 55-65. Choi, H. K. (2009). Effects of water exercise on physical fitness, pain and quality of life in patients with osteoarthritis. Unpublished master's thesis. Seoul National University of Science and Technology, Seoul. Choi, S. H. (2001). The effects of health promotion program on health of the clients with arthritis in primary health care center. Journal of Community Health Nursing, 2 (12), 344-360. Cohen, J. (1988

2014 Journal of muscle and joint health