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Latest & greatest articles for osteoarthritis
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on osteoarthritis or other clinical topics then use Trip today.
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The efficacy and duration of intra-articular corticosteroid injection for knee osteoarthritis: a systematic review of level I studies The efficacy and duration of intra-articular corticosteroid injection for knee osteoarthritis: a systematic review of level I studies The efficacy and duration of intra-articular corticosteroid injection for knee osteoarthritis: a systematic review of level I studies Hepper CT, Halvorson JJ, Duncan ST, Gregory AJ, Dunn WR, Spindler KP CRD summary The review (...) concluded that intra-articular corticosteroid injections were significantly and clinically efficacious in reducing pain caused by knee osteoarthritis. The review was generally of poor quality and the authors' conclusions are not likely to be reliable. Authors' objectives To determine the efficacy and duration of different intra-articular corticosteroid injections in reducing pain caused by knee osteoarthritis. Searching MEDLINE (to June 2006), Web of Science and The Cochrane Library were searched
exercise improved function in patients with knee osteoarthritis Statistics from Altmetric.com Study design Design: randomised controlled trial (RCT). Allocation: unclear allocation concealment.* Blinding: blinded (outcome assessors).* Study question Setting: kinesiology laboratory in Taiwan. Patients: 106 patients ⩾50 years of age (mean age 62 y, 69% women) who had bilateral knee osteoarthritis (OA) according to American College of Rheumatology criteria, radiographic changes (OA grade ⩽3, compatible (...) with mild and moderate OA), chronic knee pain for ⩾6 months, and willingness to stop medication. Intervention: weight-bearing exercise (WBE) (n = 36), non-WBE (n = 35), or no exercise (n = 35). WBE was done in a sitting position, using an EN-Dynamic resistance device (Enraf-Nonius BV, The Netherlands). With 1 foot fixed on the pedal of the device, patients fully extended and then flexed the knee joint from 90° flexion. For non-WBE, … Request Permissions If you wish to reuse any or all of this article
Effects of AR7 Joint Complex on arthralgia for patients with osteoarthritis: Results of a three-month study in Shanghai, China Osteoarthritis-induced arthralgia is a common cause of morbidity in both men and women worldwide. AR7 Joint Complex is a nutritional supplement containing various ingredients including sternum collagen II and methylsulfonylmethane. The product has been marketed in United States for over a decade, but clinical data measuring the effectiveness of this supplement (...) in relieving arthralgia is lacking. The goal of this study was to determine the effect of AR7 Joint Complex on osteoarthritis.A total of 100 patients over the age of 50 who had osteoarthritis were recruited to the double-blind study and randomly assigned into either treatment or placebo control groups. The patients in the treatment group were given AR7 Joint Complex orally, 1 capsule daily for 12 weeks, while the patients in the control group were given a placebo for the same period of time. Prior
Effect of pre-operative physiotherapy in patients with end-stage osteoarthritis undergoing hip arthroplasty To examine the effect of pre-operative physiotherapy before hip arthroplasty in patients with end-stage hip osteoarthritis.A prospective randomized controlled study.Physical medicine and rehabilitation and orthopaedic departments of Policlinico Gemelli of Rome.Twenty-three patients randomized in study and control groups.The study group took part in an educational and physiotherapy (...) programme one month before surgery. Both groups took part in the same inpatient rehabilitation programme after surgery.Both groups were evaluated one month (T0) and the day before arthroplasty (T1), after 15 days (T2), four weeks (T3) and three months (T4) post surgery, using the Barthel Index, the Short Form-36 (SF-36), the Western Ontario and McMaster Osteoarthritis Index (WOMAC), the Hip Harris Score (HHS), visual analogue scale (VAS), the British Medical Research Council (BMRC) measures of hip
Does knee malalignment mediate the effects of quadriceps strengthening on knee adduction moment, pain, and function in medial knee osteoarthritis? A randomized controlled trial To examine whether the effects of 12 weeks of quadriceps strengthening on the knee adduction moment, pain, and function in people with medial knee osteoarthritis (OA) differ in those with and without varus malalignment.A single-blind, randomized controlled trial of 107 community volunteers with medial knee OA (...) was conducted. Participants were stratified according to knee malalignment (more varus or more neutral) and then randomized into either a 12-week supervised home-based quadriceps strengthening group or a control group with no intervention. The primary outcome was the knee adduction moment, measured using 3-dimensional gait analysis. Secondary outcomes included the Western Ontario and McMaster Universities Osteoarthritis Index scores (measuring pain and physical function), step test score, stair climb test
The effects of Glucosamine Sulphate on OA of the knee joint BestBets: The effects of Glucosamine Sulphate on OA of the knee joint The effects of Glucosamine Sulphate on OA of the knee joint Report By: Michael Callaghan - Research Physiotherapist Search checked by Stephanie Pye - Physiotherapist Institution: Manchester Royal Infirmary Date Submitted: 28th June 2005 Date Completed: 8th May 2008 Last Modified: 8th May 2008 Status: Green (complete) Three Part Question In [adults with OA of the knee (...) ] do [Glucosamine Sulphate tablets] improve [Pain and Function] Clinical Scenario A middle aged lady is receiving physiotherapy for her OA knee. She mentions that her husband has heard that Glucosamine tablets are great for arthritis and is thinking of buying some from a health-food shop. She asks what you think about them. Before imparting wise words, you decide to check the evidence first. Search Strategy MEDLINE 1966-01/08, CINAHL 1982-01/08, AMED 1985-01/08, SPORTDiscus 1830-01/08, EMBASE 1996
Medical management of adults with osteoarthritis. Guidelines and Measures | Agency for Healthcare Research & Quality HHS.gov Search ahrq.gov Search ahrq.gov Menu Topics A - Z Healthcare Delivery Latest available findings on quality of and access to health care Searchable database of AHRQ Grants, Working Papers & HHS Recovery Act Projects AHRQ Projects funded by the Patient-Centered Outcomes Research Trust Fund You are here Guidelines and Measures Funding for the National Guideline Clearinghouse
Physical therapy interventions for patients with osteoarthritis of the knee: an overview of systematic reviews. Patients with osteoarthritis of the knee are commonly treated by physical therapists. Practice should be informed by updated evidence from systematic reviews. The purpose of this article is to summarize the evidence from systematic reviews on the effectiveness of physical therapy for patients with knee osteoarthritis. Systematic reviews published between 2000 and 2007 were identified (...) by a comprehensive literature search. We graded the quality of evidence across reviews for each comparison and outcome. Twenty-three systematic reviews on physical therapy interventions for patients with knee osteoarthritis were included. There is high-quality evidence that exercise and weight reduction reduce pain and improve physical function in patients with osteoarthritis of the knee. There is moderate-quality evidence that acupuncture, transcutaneous electrical nerve stimulation, and low-level laser therapy
Effectiveness of nonpharmacological and nonsurgical interventions for hip osteoarthritis: an umbrella review of high-quality systematic reviews. An increasing number of systematic reviews are available regarding nonpharmacological and nonsurgical interventions for hip osteoarthritis (OA). The objectives of this article are to identify high-quality systematic reviews on the effect of nonpharmacological and nonsurgical interventions for hip OA and to summarize available high-quality evidence (...) and that diacerein decreases radiographic OA progression. There was insufficient high-quality evidence regarding nonpharmacological and nonsurgical interventions for hip OA, and further primary studies and reviews are needed.
Hydrotherapy versus conventional land-based exercise for the management of patients with osteoarthritis of the knee: a randomized clinical trial This study was designed to evaluate the effectiveness of hydrotherapy in subjects with osteoarthritis (OA) of the knee compared with subjects with OA of the knee who performed land-based exercises.Sixty-four subjects with OA of the knee were randomly assigned to 1 of 2 groups that performed exercises for 18 weeks: a water-based exercise group (...) and a land-based exercise group. The outcome measures included a visual analog scale (VAS) for pain in the previous week, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), pain during gait assessed by a VAS at rest and immediately following a 50-foot (15.24-m) walk test (50FWT), walking time measured at fast and comfortable paces during the 50FWT, and the Lequesne Index. Measurements were recorded by a blinded investigator at baseline and at 9 and 18 weeks after initiating
Balneotherapy may be beneficial for osteoarthritis PEARLS Practical Evidence About Real Life Situations PEARLS are succinct summaries of Cochrane Systematic Reviews for primary care practitioners. They Balneotherapy may be beneficial for osteoarthritis Clinical question Is balneotherapy effective for osteoarthritis (OA)? Bottom line Balneotherapy (spa therapy, mineral baths) may improve pain and quality of life in patients with OA. Compared to no treatment, spending time in both a sulphur bath (...) , and the numbers of patients in the intervention groups varied from 10 to 97. Context OA is one of the main causes of long term disability.There is no cure for OA at present, so treatment often focuses on the management of symptoms such as pain, stiffness and immobility.Treatment options include drugs, physiotherapy and balneotherapy. Balneotherapy is an ancient and popular therapy. It involves spending time in an indoor pool filled with mineral water at a temperature of between 31°C and 34°C. Cochrane
A randomized trial of arthroscopic surgery for osteoarthritis of the knee. The efficacy of arthroscopic surgery for the treatment of osteoarthritis of the knee is unknown.We conducted a single-center, randomized, controlled trial of arthroscopic surgery in patients with moderate-to-severe osteoarthritis of the knee. Patients were randomly assigned to surgical lavage and arthroscopic débridement together with optimized physical and medical therapy or to treatment with physical and medical (...) therapy alone. The primary outcome was the total Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score (range, 0 to 2400; higher scores indicate more severe symptoms) at 2 years of follow-up. Secondary outcomes included the Short Form-36 (SF-36) Physical Component Summary score (range, 0 to 100; higher scores indicate better quality of life).Of the 92 patients assigned to surgery, 6 did not undergo surgery. Of the 86 patients assigned to control treatment, all received only
selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis and rheumatoid arthritis: a systematic review and economic evaluation Chen Y F, Jobanputra P, Barton P, Bryan S, Fry-Smith A, Harris G, Taylor R S CRD summary This review evaluated the effectiveness of cyclooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drugs (NSAIDS) for osteoarthritis (OA) and rheumatoid arthritis (RA) patients (...) . The authors concluded that COX-2 selective NSAIDs were similar to non-selective NSAIDs for the symptomatic relief of these conditions and provided superior GI tolerability. This was a well-conducted review and the authors' conclusions were likely to be reliable. Authors' objectives To evaluate the effectiveness of cyclooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drugs (NSAIDS) for osteoarthritis (OA) and rheumatoid arthritis (RA). Searching Databases searched included The Cochrane
for practice. Research : The authors stated that spa centres should co-operate to conduct research studies with a large enough sample size to detect clinically relevant differences. Funding Rheumatology and Spa Therapy Center, publically funded from Rhone-Alpes region and Savoie General Council. Bibliographic details Forestier R, Francon A. Crenobalneotherapy for limb osteoarthritis: systematic literature review and methodological analysis. Joint, Bone, Spine 2008; 75(2): 138-148 PubMedID DOI Original (...) Crenobalneotherapy for limb osteoarthritis: systematic literature review and methodological analysis Crenobalneotherapy for limb osteoarthritis: systematic literature review and methodological analysis Crenobalneotherapy for limb osteoarthritis: systematic literature review and methodological analysis Forestier R, Francon A CRD summary This review included studies comparing medical spa therapy or its components with other interventions or no intervention. Most included studies reported
Acupuncture and osteoarthritis of the knee: a review of randomized controlled trials Acupuncture and osteoarthritis of the knee: a review of randomized controlled trials Acupuncture and osteoarthritis of the knee: a review of randomized controlled trials Selfe TK, Taylor AG CRD summary The review assessed the effectiveness of acupuncture for treatment of symptoms of osteoarthritis of the knee and concluded that there was evidence that acupuncture was an effective treatment of pain and physical (...) dysfunction. The review had multiple methodological flaws and the authors conclusions are not likely to be reliable. Authors' objectives To assess the effectiveness of acupuncture for treatment of symptoms of osteoarthritis of the knee. Searching MEDLINE (1966 to 2006) and CINAHL (1982 to 2005) were searched for studies published in English; search terms were reported. Bibliographies of retrieved articles were scanned for relevant studies. Study selection Randomised controlled trials (RCTs) of the effects
Tai chi for osteoarthritis: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
The rate of decline of joint space width in patients with osteoarthritis of the knee: a systematic review and meta-analysis of randomized placebo-controlled trials of chondroitin sulfate Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
Symptomatic efficacy of avocado-soybean unsaponifiables (ASU) in osteoarthritis (OA) patients: a meta-analysis of randomized controlled trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.