Fluoroquinolones for the Treatment of Otitis Media: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines Fluoroquinolones for the Treatment of Otitis Media: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Fluoroquinolones for the Treatment of Otitis Media: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines Fluoroquinolones for the Treatment of Otitis Media: A Review of Clinical Effectiveness (...) , Cost-Effectiveness, and Guidelines Last updated: April 24, 2019 Project Number: RC1095-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of fluoroquinolones for the treatment of otitis media in patients unable to take beta-lactams antibiotics? What is the cost-effectiveness of fluoroquinolones for the treatment of otitis media in patients unable to take beta-lactams antibiotics? What are the evidence

Probiotics for preventing acute otitis media in children. Acute otitis media (AOM), or acute middle ear infection, is one of the most frequently occurring childhood diseases, and the most common reason given for prescribing antibiotics in this age group. Guidelines often recommend antibiotics as first-line treatment for severe AOM. However, antibiotics also lead to antibiotic resistance, so preventing episodes of AOM is an urgent priority.To assess the effects of probiotics to prevent (...) the occurrence and reduce the severity of acute otitis media in children.We searched CENTRAL, PubMed, Embase, and three other databases (October 2018), two trial registers (October 2018), and conducted a backwards and forwards citation analysis (August 2018). We did not apply any language, publication date, or publication status restrictions.Randomised controlled trials (RCTs) of children (aged up to 18 years), comparing probiotics with placebo, usual care, or no probiotic.Two review authors independently

Pneumococcal conjugate vaccines for preventing acute otitis media in children. Prior to introducing pneumococcal conjugate vaccines (PCVs), Streptococcus pneumoniae was most commonly isolated from middle ear fluid of children with acute otitis media (AOM). Reducing nasopharyngeal colonisation of this bacterium by PCVs may lead to a decline in AOM. The effects of PCVs deserve ongoing monitoring since studies from the post-PCV era report a shift in causative otopathogens towards non-vaccine

Oral steroids for resolution of otitis media with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial. Children with persistent hearing loss due to otitis media with effusion are commonly managed by surgical intervention. A safe, cheap, and effective medical treatment would enhance treatment options. Underpowered, poor-quality trials have found short-term benefit from oral steroids. We aimed to investigate whether a short course of oral steroids would achieve (...) acceptable hearing in children with persistent otitis media with effusion and hearing loss.In this individually randomised, parallel, double-blinded, placebo-controlled trial we recruited children aged 2-8 years with symptoms attributable to otitis media with effusion for at least 3 months and with confirmed bilateral hearing loss. Participants were recruited from 20 ear, nose, and throat (ENT), paediatric audiology, and audiovestibular medicine outpatient departments in England and Wales. Participants

Otitis media Top results for otitis media - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4 (...) ) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for otitis media The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you

Middle ear irrigation using a hydrodebrider decreases biofilm surface area in an animal model of otitis media To compare the safety and efficacy of manual and powered irrigation of the middle ear using saline or 1% baby shampoo to treat biofilm-forming bacterial middle ear infections.Biofilms play a major role in recalcitrant otitis media and are challenging to treat. Many therapeutic strategies have been attempted and the role of topical therapies is still being investigated. Topical

Grommets (ventilation tubes) for recurrent acute otitis media in children. Acute otitis media (AOM) is one of the most common childhood illnesses. While many children experience sporadic AOM episodes, an important group suffer from recurrent AOM (rAOM), defined as three or more episodes in six months, or four or more in one year. In this subset of children AOM poses a true burden through frequent episodes of ear pain, general illness, sleepless nights and time lost from nursery or school (...) recurrences per child: 0.67 versus 2.17, mean difference (MD) -1.50, 95% CI -1.99 to -1.01; low-quality evidence);- number of AOM recurrences at 12 months (one study, 200 children, one-year AOM incidence rate: 1.15 versus 1.70, incidence rate difference -0.55, 95% -0.17 to -0.93; low-quality evidence).Children receiving grommets did not have better disease-specific health-related quality of life (Otitis Media-6 questionnaire) at four (one study, 85 children) or 12 months (one study, 81 children) than

Isolated left upper eyelid ptosis with pansinusitis and contralateral otitis media in a 9-year-old boy Upper eyelid ptosis has different etiologies in children and adults. In children, the common causes include orbital cellulitis, congenital ptosis, Cranial Nerve (CN) III palsy, and Horner's syndrome. The purpose of this report is to discuss an unusual presentation of ptosis.We describe a case of a 9-year-old boy with left-sided ptosis with no apparent clinical signs of orbital or preseptal (...) infection. Magnetic resonance imaging (MRI) revealed pansinusitis and contralateral otitis media with direct extension into the superior aspect of the left orbit affecting the levator palpebrae superioris muscle.This finding on imaging disclosed the etiology of an otherwise unexplained case of upper lid ptosis.

WITHDRAWN: Grommets (ventilation tubes) for recurrent acute otitis media in children. This is an update of a Cochrane review first published in The Cochrane Library in Issue 4, 2008 and previously updated in 2011.Acute suppurative otitis media is one of the most common infectious diseases in childhood. Recurrent acute otitis media is defined for the purposes of this review as either three or more acute infections of the middle ear cleft in a six-month period, or at least four episodes in a year (...) . Strategies for managing the condition include the assessment and modification of risk factors where possible, repeated courses of antibiotics for each new infection, antibiotic prophylaxis and the insertion of ventilation tubes (grommets).To establish whether grommet insertion reduces the frequency of episodes of recurrent acute otitis media and the proportion of symptomatic children.The Cochrane Ear, Nose and Throat Disorders Group (CENTDG) Trials Search Co-ordinator searched the CENTDG Trials Register

Otitis media (acute): antimicrobial prescribing Otitis media (acute Otitis media (acute): antimicrobial ): antimicrobial prescribing prescribing NICE guideline Published: 28 March 2018 nice.org.uk/guidance/ng91 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration (...) be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Otitis media (acute): antimicrobial prescribing (NG91) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 21Contents Contents Overview 4 Who

Systemic corticosteroids for acute otitis media in children. Acute otitis media (AOM) is a common acute infection in children. Pain is its most prominent and distressing symptom. Antibiotics are commonly prescribed for AOM, although they have only a modest effect in reducing pain at two to three days. There is insufficient evidence for benefits of other treatment options, including systemic corticosteroids. However, systemic corticosteroids are potent anti-inflammatory drugs, and so

A Clinical Trial of Proton Pump Inhibitors to Treat Children with Chronic Otitis Media with Effusion. Gastroesophageal reflux (GER) is considered a cause of otitis media with effusion (OME). This study aimed to investigate whether OME can be effectively treated with a proton pump inhibitor (PPI), therefore implicating GER as a causative factor of OME.A PPI or placebo was randomly administered to enrolled subjects for 4-8 weeks. To monitor effusion status, subjects underwent monthly pneumatic

Acute otitis media Acute otitis media - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Acute otitis media Last reviewed: February 2019 Last updated: July 2018 Summary May present with otalgia, irritability, decreased hearing, anorexia, vomiting, or fever, usually in the presence of an ongoing viral respiratory infection. Physical examination will reveal a bulging, opacified tympanic membrane with decreased mobility (...) . The membrane may be white, yellow, pink, or red. Diagnosis is generally made with conventional otoscopy. Additional tests might include pneumatic otoscopy or tympanometry to confirm the presence of an effusion. Treatment includes pain control with analgesics and might include antibiotics. Complications include perforation of the tympanic membrane and, rarely, mastoiditis, seventh cranial nerve palsy, or sigmoid sinus thrombosis. Definition Acute otitis media (AOM) is an infection involving the middle ear

Otitis media - acute Otitis media - acute - NICE CKS Share Otitis media - acute: Summary Acute otitis media (AOM) is defined as the presence of inflammation in the middle ear, associated with an effusion, and accompanied by the rapid onset of symptoms and signs of an ear infection. It is a common condition that can be caused by both viruses and bacteria. AOM occurs frequently in children but is less common in adults. It most commonly affects children from birth to 4 years of age, especially (...) — avoiding exposure to passive smoking, use of dummies, and flat, supine feeding; and ensuring that children have had a complete course of pneumococcal vaccinations as part of the routine childhood immunization schedule. In adults — avoiding smoking and/or passive smoking. Have I got the right topic? Have I got the right topic? From age 1 month onwards. This CKS topic is largely based on a National Institute for Health and Care Excellence (NICE) guideline Otitis media (acute): antimicrobial prescribing

Influenza vaccines for preventing acute otitis media in infants and children. Acute otitis media (AOM) is one of the most common infectious diseases in children. It has been reported that 64% of infants have an episode of AOM by the age of six months and 86% by one year. Although most cases of AOM are due to bacterial infection, it is commonly triggered by a viral infection. In most children AOM is self limiting, but it does carry a risk of complications. Since antibiotic treatment increases (...) the risk of antibiotic resistance, influenza vaccines might be an effective way of reducing this risk by preventing the development of AOM.To assess the effectiveness of influenza vaccine in reducing the occurrence of acute otitis media in infants and children.We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, CINAHL, LILACS, Web of Science, the WHO International Clinical Trials Registry Platform, and ClinicalTrials.gov (15 February 2017). We also searched

Prognostic Factors for Treatment Failure in Acute Otitis Media Antimicrobial treatment is effective in the management of acute otitis media (AOM), but approximately half of the children may recover without antimicrobial agents. By identifying patients who may not require antimicrobial treatment for the management of AOM, the use of antimicrobial agents could be substantially reduced. Our aim was to identify subgroups of children with AOM who would benefit most from antimicrobial treatment

Bezold's abscess: A rare complication of acute otitis media Otitis media is a common disease encountered in the primary practice. Most cases are successfully treated with antibiotics without any sequelae. Because of these, potential serious complications of otitis media may be overlooked. We report a rare case of Bezold's abscess, as a complication of otitis media and discuss its pathophysiology and management.

Montelukast versus inhaled mometasone for treatment of otitis media with effusion in children: A randomized controlled trial Otitis media is one of the most common infections among children and is a complication in about 30% of common colds. The most common complication of acute otitis media is otitis media with effusion. Some studies have reported the effects of montelukast and mometasone nasal spray in treatment of otitis media with effusion. However, current information is inadequate (...) in this issue.To compare the effectiveness of montelukast and mometasone nasal spray in treatment of otitis media with effusion in children attending Koodakan hospital in Bandar Abbas, Iran.This randomized controlled trial was done on 2- to 6-year-old children attending Koodakan Hospital in Bandar Abbas, southern Iran, in 2014. Patients were divided into three groups of montelukast, mometasone, and control group. Audiometry was done for all patients at baseline and four weeks after treatment. Patients were

Supplemental Project to Assess the Transparency of Reporting Requirements: Tympanostomy Tubes in Children With Otitis Media Methods Research Report Supplemental Project To Assess the Transparency of Reporting Requirements: Tympanostomy Tubes in Children With Otitis Media Methods Research Report Supplemental Project To Assess the Transparency of Reporting Requirements: Tympanostomy Tubes in Children With Otitis Media Prepared for: Agency for Healthcare Research and Quality U.S. Department (...) . Supplemental Project to Assess the Transparency of Reporting Requirements: Tympanostomy Tubes in Children With Otitis Media. Methods Research Report. (Prepared by the Brown University Evidence-based Practice Center under Contract No. 290-2015-00002-I; 290-32004-T). AHRQ Publication No. 17-EHC018-EF. Rockville, MD: Agency for Healthcare Research and Quality. June 2017. www.effectivehealthcare.ahrq.gov/reports/final.cfm. DOI: https://doi.org/10.23970/ AHRQEPCMETH2. ii Preface The Agency for Healthcare

Tympanostomy tubes in children with otitis media Tympanostomy tubes in children with otitis media Tympanostomy tubes in children with otitis media Steel D, Adam GP, Di M, Halladay C, Pan I, Coppersmith N, Balk EM, Trikalinos TA Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Steel D, Adam GP, Di M, Halladay C, Pan I, Coppersmith N, Balk EM, Trikalinos TA (...) . Tympanostomy tubes in children with otitis media. Rockville: Agency for Healthcare Research and Quality (AHRQ). Comparative Effectiveness Review No. 185. 2017 Authors' objectives The objectives for the systematic review are to synthesize information on the effectiveness of tympanostomy tubes (TT) in children with chronic otitis media with effusion and recurrent acute otitis media, summarize the frequency of adverse effects or complications associated with TT placement, synthesize information