Latest & greatest articles for otitis media

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This page lists the very latest high quality evidence on otitis media and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for otitis media

121. Evidence assessment of management of acute otitis media - I. The role of antibiotics in treatment of uncomplicated acute otitis media

Evidence assessment of management of acute otitis media - I. The role of antibiotics in treatment of uncomplicated acute otitis media Evidence assessment of management of acute otitis media - I. The role of antibiotics in treatment of uncomplicated acute otitis media Evidence assessment of management of acute otitis media - I. The role of antibiotics in treatment of uncomplicated acute otitis media Takata G S, Chan L S, Shekelle P, Morton S C, Mason W, Marcy S M Authors' objectives (...) To synthesise the literature on the natural history of acute otitis media (AOM), the effectiveness of antibiotic treatment in uncomplicated AOM, and the relative effectiveness of specific antibiotic regimens. Searching The following sources were searched: MEDLINE from 1966 to March 1999; the Cochrane Library (to March 1999); HealthSTAR from 1975 to March 1999; International Pharmaceutical Abstracts from 1970 to March 1999; CINAHL from 1982 to March 1999; BIOSIS Previews from 1970 to March 1999; and EMBASE

2001 DARE.

122. Azithromycin vs. clarithromycin and co-amoxiclav: clinical and economic comparison in the treatment of acute otitis media in children

Azithromycin vs. clarithromycin and co-amoxiclav: clinical and economic comparison in the treatment of acute otitis media in children Azithromycin vs. clarithromycin and co-amoxiclav: clinical and economic comparison in the treatment of acute otitis media in children Azithromycin vs. clarithromycin and co-amoxiclav: clinical and economic comparison in the treatment of acute otitis media in children Kawalski H, Blacha E, Kopacz M, Mos M, Cierpiol-Tracz E, Welniak M, Dudziak B, Bojda S, Kossowska (...) B, Gatniejewska E, Ligacz M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of azithromycin, clarithromycin and co-amoxiclav in the treatment of children with acute otitis media (AOM). Azithromycin was administered

2001 NHS Economic Evaluation Database.

123. Interventions for chronic suppurative otitis media. (Abstract)

Interventions for chronic suppurative otitis media. Chronic suppurative otitis media (CSOM) is a serious bacterial infection of the middle ear that can follow untreated acute otitis media.To assess the effects of different treatments for CSOM.We searched Medline from 1966 to 1996 and a bibliographic collection of the Hearing Impairment Research Group in Liverpool, UK. We handsearched two otolaryngology journals and contacted members of an international hearing network.Randomized trials of any

2000 Cochrane

124. Short course antibiotics for acute otitis media. (Abstract)

Short course antibiotics for acute otitis media. Otitis media is a common pediatric problem, for which antibiotics are frequently prescribed.To determine the effectiveness of a short course of antibiotics (less than seven days) in comparison to a longer course (seven days or greater) for the treatment of acute otitis media in children.The medical literature was searched for randomized controlled studies of the treatment of ear infections in children with antibiotics published from January 1966

2000 Cochrane

125. Antibiotics for acute otitis media in children. Full Text available with Trip Pro

Antibiotics for acute otitis media in children. Acute otitis media is one of the most common diseases in early infancy and childhood. Antibiotic use for acute otitis media varies from 31% in the Netherlands to 98% in the USA and Australia.The objective of this review was to assess the effects of antibiotics for children with acute otitis media.We searched the Cochrane Controlled Trials Register, MEDLINE, Index Medicus, Current Contents and reference lists of articles from 1958 to January 1999 (...) complications seen in these trials: only one case of mastoiditis occurred (in a penicillin treated group). One semi-randomised trial in Sweden in 1954 reported a rate of 17% in the untreated group versus none in the penicillin treated groups.Antibiotics provide a small benefit for acute otitis media in children. As most cases will resolve spontaneously, this benefit must be weighed against the possible adverse reactions. Antibiotic treatment may play an important role in reducing the risk of mastoiditis

2000 Cochrane

126. Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years. Full Text available with Trip Pro

Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years. To determine the effect of antibiotic treatment for acute otitis media in children between 6 months and 2 years of age.Practice based, double blind, randomised, placebo controlled trial.53 general practices in the Netherlands.240 children aged 6 months to 2 years with the diagnosis of acute otitis media.Amoxicillin 40 mg/kg/day in three doses.Persistent symptoms (...) in the placebo group during the first 10 days (4.1 v 2.3 doses, P=0.004). In addition, no otoscopic differences were observed at days four and 11, and tympanometric findings at six weeks were similar in both groups.Seven to eight children aged 6 to 24 months with acute otitis media needed to be treated with antibiotics to improve symptomatic outcome at day four in one child. This modest effect does not justify prescription of antibiotics at the first visit, provided close surveillance can be guaranteed.

2000 BMJ Controlled trial quality: predicted high

127. Treatment of acute otitis media with an antiadhesive oligosaccharide: a randomised, double-blind, placebo-controlled trial. (Abstract)

Treatment of acute otitis media with an antiadhesive oligosaccharide: a randomised, double-blind, placebo-controlled trial. Antiadhesive compounds are promising candidates for prevention or treatment of infections. We have investigated the efficacy of such an agent, 3'-sialyllacto-N-neotetraose (NE-1530), given intranasally for prophylaxis of acute otitis media and for effect on nasopharyngeal carriage of bacteria.We did a randomised, double-blind placebo-controlled study at one study site. 507 (...) of acute otitis media was diagnosed in 108 (43%) of 254 children in the NE-1530 group and in 86 (34%) of 253 children in the placebo group. The efficacy of treatment was negative, -27% (95% CI -68 to 5; p=0.10). The nasopharyngeal carriage of S pneumoniae, H. influenzae, and M. catarrhalis was not affected by treatment, and the adverse event profiles were almost identical for NE-1530 and placebo.NE-1530 did not have a beneficial effect on the occurrence of acute otitis media or on the nasopharyngeal

2000 Lancet Controlled trial quality: predicted high

128. Childhood vaccination against pneumococcal otitis media and pneumonia: an analysis of benefits and costs

Childhood vaccination against pneumococcal otitis media and pneumonia: an analysis of benefits and costs Childhood vaccination against pneumococcal otitis media and pneumonia: an analysis of benefits and costs Childhood vaccination against pneumococcal otitis media and pneumonia: an analysis of benefits and costs Weycker D, Richardson E, Oster G Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief (...) summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of a heptavalent pneumococcal conjugate vaccine (PNCRM7) in children aged younger than 5 years, for the prevention of acute otitis media (AOM), community-acquired pneumonia (CAP), and tympanostomy and related procedures (TRP). Type of intervention Primary prevention (paediatric vaccination). Economic study type Cost

2000 NHS Economic Evaluation Database.

129. Adenoidectomy and adenotonsillectomy for recurrent acute otitis media: parallel randomized clinical trials in children not previously treated with tympanostomy tubes. (Abstract)

Adenoidectomy and adenotonsillectomy for recurrent acute otitis media: parallel randomized clinical trials in children not previously treated with tympanostomy tubes. Adenoidectomy and adenotonsillectomy are commonly performed in US children to reduce the occurrence of persistent or recurrent otitis media, but evidence supporting the efficacy of the operations is limited.To test the efficacy of adenoidectomy and adenotonsillectomy in children with persistent or recurrent otitis media who had (...) an adenoidectomy, adenotonsillectomy, or control group; children who had such conditions (157 enrolled; 144 followed up) were randomized to an adenotonsillectomy or control group.Occurrence rate of episodes of acute otitis media by treatment group and estimated proportion of time with otitis media.In both trials, most subjects were eligible because of recurrent acute otitis media, with or without persistent otitis media with effusion. A total of 47 children assigned to surgical treatment groups had no surgery

1999 JAMA Controlled trial quality: predicted high

130. Screening programmes for the detection of otitis media with effusion and conductive hearing loss in pre-school and new entrant school children: a critical appraisal of the literature

Screening programmes for the detection of otitis media with effusion and conductive hearing loss in pre-school and new entrant school children: a critical appraisal of the literature Screening programmes for the detection of otitis media with effusion and conductive hearing loss in pre-school and new entrant school children: a critical appraisal of the literature Screening programmes for the detection of otitis media with effusion and conductive hearing loss in pre-school and new entrant school (...) children: a critical appraisal of the literature New Zealand Health Technology Assessment Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation New Zealand Health Technology Assessment. Screening programmes for the detection of otitis media with effusion and conductive hearing loss in pre-school and new entrant school children: a critical appraisal

1998 Health Technology Assessment (HTA) Database.

131. A comparison of the effectiveness of pharmacologic treatment of otitis media with effusion in children: integrative and meta-analysis

A comparison of the effectiveness of pharmacologic treatment of otitis media with effusion in children: integrative and meta-analysis A comparison of the effectiveness of pharmacologic treatment of otitis media with effusion in children: integrative and meta-analysis A comparison of the effectiveness of pharmacologic treatment of otitis media with effusion in children: integrative and meta-analysis Witmer A, Wells A M, Seymour R J Authors' objectives To compare the effectiveness (...) of pharmacological treatment versus placebo in otitis media with effusion in children. Searching Searches were conducted of the following using the keywords 'otitis media with effusion': MEDLINE ( including Avicenna) and CINAHL (1980 to 1997); and the Internet using the search engines Yahoo (first 60 out of 8,050 hits were reviewed) and Infoseek (first 50 out of over 12,000,000 hits were reviewed). Reference lists of 12 articles obtained from 32 abstracts were examined. Reviews were excluded for the meta

1998 DARE.

132. Treatment of acute otitis media with a shortened course of antibiotics: a meta-analysis

Treatment of acute otitis media with a shortened course of antibiotics: a meta-analysis Treatment of acute otitis media with a shortened course of antibiotics: a meta-analysis Treatment of acute otitis media with a shortened course of antibiotics: a meta-analysis Kozyrskyj A L, Hildes-Ripstein G E, Longstaffe S E, Wincott J L, Sitar D S, Klassen T P, Moffatt M E Authors' objectives To conduct a meta-analysis of randomised controlled trials of antibiotic treatment of acute otitis media (AOM (...) ) in children to determine whether outcomes are comparable in children treated with antibiotics for less than 7 days or at least 7 days or more. Searching MEDLINE (JANUARY 1966 TO July 1997), EMBASE (January 1974 to July 1997), Current Contents (January to July 1997), and Science Citation Index were searched. There were no language restrictions. In MEDLINE, search terms employed were "otitis media" in medical subject headings, modified by "acute" in the title or abstract. These terms were combined

1998 DARE.

133. Screening programmes for the detection of otitis media with effusion and conductive hearing loss in pre-school and new entrant school children: a critical appraisal of the literature

Screening programmes for the detection of otitis media with effusion and conductive hearing loss in pre-school and new entrant school children: a critical appraisal of the literature Screening programmes for the detection of otitis media with effusion and conductive hearing loss in pre-school and new entrant school children: a critical appraisal of the literature Screening programmes for the detection of otitis media with effusion and conductive hearing loss in pre-school and new entrant school (...) children: a critical appraisal of the literature New Zealand Health Technology Assessment Authors' objectives To review the effectiveness of pre-school and school entrant screening programmes for otitis media with effusion (OME) and conductive hearing loss. The effectiveness of treatments for OME is also reviewed. Searching The following electronic databases were searched: MEDLINE (1966-Jan 1998); Health STAR (1975-Jan 1998); CINAHL (1982-Jan 1998); Current Contents (start-Mar 1998); Cochrane Library

1998 DARE.

134. Antibiotic treatment of acute otitis media in children under two years of age: evidence based?

Antibiotic treatment of acute otitis media in children under two years of age: evidence based? Antibiotic treatment of acute otitis media in children under two years of age: evidence based? Antibiotic treatment of acute otitis media in children under two years of age: evidence based? Damoiseaux R A, van Balen F A, Hoes A W, De Melker R A Authors' objectives To assess whether the current high prescription rates of antibiotics for acute otitis media (AOM) in children under two years of age (being (...) a risk group for poor outcome) are based on an established increased efficacy. Searching MEDLINE (1966 to January 1997) and EMBASE (1974 to January 1997) were searched using the following keywords; otitis media, child, clinical trial, and placebo. The reference sections of these articles and of several major review articles were checked for further articles. An extensive handsearch for clinical trials of therapy for AOM in patients of all ages was performed by the authors' group in 1991 (see Other

1998 DARE.

135. Macrolides in community-acquired pneumonia and otitis media - summary

Macrolides in community-acquired pneumonia and otitis media - summary Macrolides in community-acquired pneumonia and otitis media Macrolides in community-acquired pneumonia and otitis media Perras C Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Perras C. Macrolides in community-acquired pneumonia and otitis media. Ottawa: Canadian (...) /therapeutic use; Otitis Media; Pneumonia Language Published English, French Country of organisation Canada Address for correspondence 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553, Fax: +1 613 226 5392; Email: jills@ccohta.ca AccessionNumber 31998008137 Date bibliographic record published 28/02/1998 Date abstract record published 28/02/1998 Health Technology Assessment (HTA) database Copyright © 2019 Canadian Coordinating Office for Health Technology Assessment Homepage Options

1997 Health Technology Assessment (HTA) Database.

136. Pharmacoeconomic impact of factors affecting compliance with antibiotic regimens in the treatment of acute otitis media

Pharmacoeconomic impact of factors affecting compliance with antibiotic regimens in the treatment of acute otitis media Pharmacoeconomic impact of factors affecting compliance with antibiotic regimens in the treatment of acute otitis media Pharmacoeconomic impact of factors affecting compliance with antibiotic regimens in the treatment of acute otitis media Wandstrat T L, Kaplan B Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS (...) EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Treatment of otitis media with antibiotics. Type of intervention Treatment. Economic study type Cost-effectiveness study. Study population Children of both sexes aged between 2 months and 7 years old with acute otitis media. Setting Primary care. The economic study was conducted in West

1997 NHS Economic Evaluation Database.

137. Macrolides in community-acquired pneumonia and otitis media

Macrolides in community-acquired pneumonia and otitis media Macrolides in community-acquired pneumonia and otitis media Macrolides in community-acquired pneumonia and otitis media Canadian Coordinating Office for Health Technology Assessment Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment (...) on the reliability of the study and the conclusions drawn. Health technology The use of three macrolides; erythromycin compared toazithromycin or clarithromycin for the treatment of community acquired pneumonia (CAP) and otitis media. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population Patients who had received a macrolide, specifically erythromycin, azithromycin or clarithromycin for the treatment of CAP and otitis media. Setting Primary care. The economic study

1997 NHS Economic Evaluation Database.

138. Double-blind randomised trial of co-amoxiclav versus placebo for persistent otitis media with effusion in general practice. (Abstract)

Double-blind randomised trial of co-amoxiclav versus placebo for persistent otitis media with effusion in general practice. The treatment of persistent otitis media with effusion (OME) remains controversial, but this condition is the commonest reason for children to require ear, nose, and throat (ENT) surgery. Trials of antibiotics are inconclusive, are often weak methodologically, and have not been done in general practice. Our aim was a trial of an antibiotic for OME in such a population.433

1996 Lancet Controlled trial quality: predicted high

139. Randomised controlled trial of treatment of chronic suppurative otitis media in Kenyan schoolchildren. (Abstract)

Randomised controlled trial of treatment of chronic suppurative otitis media in Kenyan schoolchildren. The outcomes of treatment of chronic suppurative otitis media (CSOM) are disappointing and uncertain, especially in developing countries. Because CSOM is the commonest cause of hearing impairment in children in these countries, an effective method of management that can be implemented on a wide scale is needed. We report a randomised, controlled trial of treatment of CSOM among children

1996 Lancet Controlled trial quality: predicted high

140. Xylitol chewing gum in prevention of acute otitis media: double blind randomised trial. Full Text available with Trip Pro

Xylitol chewing gum in prevention of acute otitis media: double blind randomised trial. To examine whether xylitol, which reduces the growth of Streptococcus pneumoniae, might have clinical importance in the prevention of acute otitis media.A double blind randomised trial with xylitol administered in chewing gum.Eleven day care nurseries in the city of Oulu. Most of the children had had problems with recurrent acute otitis media.306 day care children: 149 children in the sucrose group (76 boys (...) ; mean (SD) age 4.9 (1.5) years) and 157 in the xylitol group (80 boys; 5.0 (1.4) years).Either xylitol (8.4 g a day) or sucrose (control) chewing gum for two months.The occurrence of acute otitis media and antimicrobial treatment received during the intervention and nasopharyngeal carriage of S pneumoniae.During the two month monitoring period at least one event of acute otitis media was experienced by 31/149 (20.8%) children who received sucrose compared with 19/157 (12.1%) of those receiving

1996 BMJ Controlled trial quality: predicted high