Latest & greatest articles for pneumonia

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This page lists the very latest high quality evidence on pneumonia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for pneumonia

521. Weekly versus daily changes of in-line suction catheters: impact on rates of ventilator-associated pneumonia and associated costs

Weekly versus daily changes of in-line suction catheters: impact on rates of ventilator-associated pneumonia and associated costs Weekly versus daily changes of in-line suction catheters: impact on rates of ventilator-associated pneumonia and associated costs Weekly versus daily changes of in-line suction catheters: impact on rates of ventilator-associated pneumonia and associated costs Stoller J K, Orens D K, Fatica C, Elliott M, Kester L, Woods J, Hoffman-Hogg L, Karafa M T, Arroliga AC (...) Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology In-line suction catheters (ILSC) were used to reduce the risk of ventilator-associated pneumonia (VAP) during the mechanical ventilation of patients suffering from respiratory failure

2003 NHS Economic Evaluation Database.

522. Does bronchoalveolar lavage enhance our ability to treat ventilator-associated pneumonia in a trauma-burn intensive care unit? Full Text available with Trip Pro

Does bronchoalveolar lavage enhance our ability to treat ventilator-associated pneumonia in a trauma-burn intensive care unit? Does bronchoalveolar lavage enhance our ability to treat ventilator-associated pneumonia in a trauma-burn intensive care unit? Does bronchoalveolar lavage enhance our ability to treat ventilator-associated pneumonia in a trauma-burn intensive care unit? Wahl W L, Franklin G A, Brandt M M, Sturm L, Ahrns K S, Hemmila M R, Arbabi S Record Status This is a critical (...) abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The study compared diagnosis of ventilator-associated pneumonia (VAP) with and without bronchoalveolar lavage (BAL). A surgical resident or the trauma-attending physician performed BAL. BAL involved passing

2003 NHS Economic Evaluation Database.

523. Decision analysis of antibiotic and diagnostic strategies in ventilator-associated pneumonia Full Text available with Trip Pro

Decision analysis of antibiotic and diagnostic strategies in ventilator-associated pneumonia Decision analysis of antibiotic and diagnostic strategies in ventilator-associated pneumonia Decision analysis of antibiotic and diagnostic strategies in ventilator-associated pneumonia Ost D E, Hall C S, Joseph G, Ginocchio C, Condon S, Kao E, Larusso M, Itzla R, Fein A M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology This study considered the treatment of ventilator-associated pneumonia (VAP). Four diagnostic strategies were considered in conjunction with four antibiotic regimens. The diagnostic strategies were no diagnostic test (empirical treatment only), quantitative nonprotected endotracheal cultures, bronchoscopy

2003 NHS Economic Evaluation Database.

524. Impact of a program of intensive surveillance and interventions targeting ventilated patients in the reduction of ventilator-associated pneumonia and its cost-effectiveness Full Text available with Trip Pro

Impact of a program of intensive surveillance and interventions targeting ventilated patients in the reduction of ventilator-associated pneumonia and its cost-effectiveness Impact of a program of intensive surveillance and interventions targeting ventilated patients in the reduction of ventilator-associated pneumonia and its cost-effectiveness Impact of a program of intensive surveillance and interventions targeting ventilated patients in the reduction of ventilator-associated pneumonia and its (...) observational study in which the interventions were introduced at different stages over a period of 2 years. The house staff and the ICU attending physicians were not aware of the implementation of the programme. Hence, the diagnosis of pneumonia is not likely to have been influenced by knowledge of the interventions. Data were collected for two years and each patient was followed-up during ventilation and for 48 hours after extubation. Analysis of effectiveness The primary outcomes used in the analysis

2003 NHS Economic Evaluation Database.

525. Impact of initial antibiotic choice on clinical outcomes in community-acquired pneumonia: analysis of a hospital claims-made database

Impact of initial antibiotic choice on clinical outcomes in community-acquired pneumonia: analysis of a hospital claims-made database Impact of initial antibiotic choice on clinical outcomes in community-acquired pneumonia: analysis of a hospital claims-made database Impact of initial antibiotic choice on clinical outcomes in community-acquired pneumonia: analysis of a hospital claims-made database Brown R B, Iannini P, Gross P, Kunkel M Record Status This is a critical abstract of an economic (...) evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Patients with community-acquired pneumonia (CAP) were given one of nine types of antibiotic treatments, five of which were monotherapies and four of which were dual therapies. The monotherapies were ceftriaxone, macrolides, "other

2003 NHS Economic Evaluation Database.

526. Pharmacoeconomic aspects of antibacterial therapy with azithromycin of community-acquired pneumonia in servicemen

Pharmacoeconomic aspects of antibacterial therapy with azithromycin of community-acquired pneumonia in servicemen Pharmacoeconomic aspects of antibacterial therapy with azithromycin of community-acquired pneumonia in servicemen Pharmacoeconomic aspects of antibacterial therapy with azithromycin of community-acquired pneumonia in servicemen Dzyublyk O Y, Mukhin O O, Simonov S S Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED (...) . Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of oral azithromycin (Sumamed PLIVA, Croatia) in the treatment of community-acquired pneumonia (CAP) was examined. The drug regimen was 500 mg given orally once daily for 3 days. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study

2003 NHS Economic Evaluation Database.

527. Microscopic examination of intracellular organisms in protected bronchoalveolar mini-lavage fluid for the diagnosis of ventilator-associated pneumonia

Microscopic examination of intracellular organisms in protected bronchoalveolar mini-lavage fluid for the diagnosis of ventilator-associated pneumonia PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2003 PedsCCM Evidence-Based Journal Club

528. Comparison of 8 vs 15 Days of Antibiotic Therapy for Ventilator-Associated Pneumonia in Adults: A Randomized Trial

Comparison of 8 vs 15 Days of Antibiotic Therapy for Ventilator-Associated Pneumonia in Adults: A Randomized Trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2003 PedsCCM Evidence-Based Journal Club

529. Chlamydia pneumoniae as an emerging risk factor in cardiovascular disease. (Abstract)

Chlamydia pneumoniae as an emerging risk factor in cardiovascular disease. Recent appreciation of atherosclerosis as a chronic, inflammatory disease has rekindled efforts to examine the role that infectious agents may play in atherogenesis. In particular, much interest has focused on infection with Chlamydia pneumoniae. The possibility that a prokaryote contributes to atherogenesis has high clinical interest, as C pneumoniae infection may be a treatable risk factor. To review the evidence (...) implicating C pneumoniae in the pathogenesis of atherosclerosis, we searched MEDLINE for articles published between January 1966 and October 2002 on the association of C pneumoniae and atherosclerosis. We also used online resources, texts, meeting abstracts, and expert opinion. We included 5 types of studies (epidemiological, pathology based, animal model, cell biology, and human antibiotic treatment trials) and extracted diagnostic, pathophysiologic, and therapeutic information from the selected

2002 JAMA

530. Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis. (Abstract)

Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis. Increased intestinal epithelial apoptosis is present in both human autopsy studies and animal models of sepsis. Whether altering gut apoptosis decreases mortality in sepsis induced by pathogenic bacteria outside the gut is unknown.To determine if decreasing levels of intestinal cell death improves survival in a murine model of Pseudomonas aeruginosa pneumonia-induced sepsis.Prospective (...) intratracheal injection of P aeruginosa (P =.001), with differences in survival noted within 24 hours of surgery. Overexpression of Bcl-2 was associated with a decrease in gut epithelial apoptosis demonstrated by active caspase 3 staining, the terminal deoxynucleotidyltransferase-mediated dUTP nick end-labeling assay, and hematoxylin-eosin staining.In this murine model, inhibiting gut epithelial apoptosis by overexpression of Bcl-2 was associated with a survival advantage in P aeruginosa pneumonia-induced

2002 JAMA

531. Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. (Abstract)

Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Between 1986 and 1998, eight cases of community-acquired pneumonia due to Staphylococcus aureus strains carrying the gene for the Panton-Valentine leukocidin (PVL) were recorded in France, six of which were fatal. We aimed to assess the clinical features of these eight cases, and those of other cases identified prospectively (...) , and to compare them with the characteristics of patients with pneumonia caused by PVL-negative strains.We compared eight retrospective and eight prospective cases of PVL-positive S aureus pneumonia with 36 cases of PVL-negative S aureus pneumonia. For all patients, we recorded age, length of hospital stay, risk factors for infection, signs and symptoms, laboratory findings, antibiotic treatment, and serial radiological findings.Median age was 14.8 years (IQR 5.4-24.0) for the PVL-positive patients and 70.1

2002 Lancet

532. Clinical efficacy of 3 days versus 5 days of oral amoxicillin for treatment of childhood pneumonia: a multicentre double-blind trial. (Abstract)

Clinical efficacy of 3 days versus 5 days of oral amoxicillin for treatment of childhood pneumonia: a multicentre double-blind trial. For most infections, especially acute respiratory infections (ARIs), the recommended duration of therapy is not based on strong scientific or clinical criteria. Shorter courses of antibiotics for non-severe pneumonia would result in lower costs, enhance patient compliance, and might help to contain antimicrobial resistance. We aimed to compare the clinical (...) efficacy of 3-day and 5-day courses of amoxicillin in children with non-severe pneumonia.We recruited 2000 children, aged 2-59 months, with non-severe pneumonia (WHO criteria) diagnosed in the outpatient departments of seven hospitals. Patients were randomly assigned to 3 days or 5 days of treatment with oral amoxicillin. The primary outcome was treatment failure. Analyses were by intention to treat.We allocated 1000 children to 3 days of treatment and 1000 to 5 days. Treatment failed in 209 (21

2002 Lancet Controlled trial quality: predicted high

533. Usefulness of clinical pathway for community-acquired pneumonia as both an educational and a cost-management tool: an intervention study to compare the usefulness of management with a critical pathway to historical control of conventional management

Usefulness of clinical pathway for community-acquired pneumonia as both an educational and a cost-management tool: an intervention study to compare the usefulness of management with a critical pathway to historical control of conventional management Usefulness of clinical pathway for community-acquired pneumonia as both an educational and a cost-management tool: an intervention study to compare the usefulness of management with a critical pathway to historical control of conventional management (...) Usefulness of clinical pathway for community-acquired pneumonia as both an educational and a cost-management tool: an intervention study to compare the usefulness of management with a critical pathway to historical control of conventional management Aoshima M, Satoh T, Uchiyama N, Chonabayashi N Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed

2002 NHS Economic Evaluation Database.

534. Chloramphenicol versus benzylpenicillin and gentamicin for the treatment of severe pneumonia in children in Papua New Guinea: a randomised trial. (Abstract)

Chloramphenicol versus benzylpenicillin and gentamicin for the treatment of severe pneumonia in children in Papua New Guinea: a randomised trial. Pneumonia is the most frequent cause of child mortality in less-developed countries. We aimed to establish whether the combination of benzylpenicillin and gentamicin or chloramphenicol would be better as first-line treatment in children with severe pneumonia in Papua New Guinea.We did an open randomised trial in which we enrolled children aged 1 month (...) to 5 years of age who fulfilled the WHO criteria for very severe pneumonia and who presented to hospitals in two provinces. Children were randomly assigned to receive chloramphenicol (25 mg/kg 6 hourly) or benzylpenicillin (50 mg/kg 6 hourly) plus gentamicin (7.5 mg/kg daily) by intramuscular injection. The primary outcome measure was a good or an adverse outcome.1116 children were enrolled; 559 children were treated with chloramphenicol and 557 with benzylpenicillin and gentamicin. At presentation

2002 Lancet Controlled trial quality: predicted high

535. Effect of routine zinc supplementation on pneumonia in children aged 6 months to 3 years: randomised controlled trial in an urban slum. Full Text available with Trip Pro

Effect of routine zinc supplementation on pneumonia in children aged 6 months to 3 years: randomised controlled trial in an urban slum. To evaluate the effect of daily zinc supplementation in children on the incidence of acute lower respiratory tract infections and pneumonia.Double masked, randomised placebo controlled trial.A slum community in New Delhi, India.2482 children aged 6 to 30 months.Daily elemental zinc, 10 mg to infants and 20 mg to older children or placebo for four months. Both (...) who had acute lower respiratory tract infection during follow up was no different in the two groups (absolute risk reduction -0.2%, 95% confidence interval -3.9% to 3.6%). Zinc supplementation resulted in a lower incidence of pneumonia than placebo (absolute risk reduction 2.5%, 95% confidence interval 0.4% to 4.6%). After correction for multiple episodes in the same child by generalised estimating equations analysis the odds ratio was 0.74, 95% confidence interval 0.56 to 0.99.Zinc

2002 BMJ Controlled trial quality: predicted high

536. Effect of an education program aimed at reducing the occurrence of ventilator associated pneumonia

Effect of an education program aimed at reducing the occurrence of ventilator associated pneumonia Effect of an education program aimed at reducing the occurrence of ventilator associated pneumonia Effect of an education program aimed at reducing the occurrence of ventilator associated pneumonia Zack J E, Garrison T, Trovillion E, Clinkscale D, Coopersmith C M, Fraser V J, Kollef M H Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS (...) EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology An educational programme directed toward respiratory care practitioners and intensive care unit (ICU) nurses was considered. The programme consisted of a 10 page self study module on risk factors and practice modifications involved in ventilator associated pneumonia (VAP, inservices at staff

2002 NHS Economic Evaluation Database.

537. Cost-effectiveness analysis of ambulatory treatment for adult patients with community-acquired pneumonia: according to Japanese Respiratory Society guidelines

Cost-effectiveness analysis of ambulatory treatment for adult patients with community-acquired pneumonia: according to Japanese Respiratory Society guidelines Cost-effectiveness analysis of ambulatory treatment for adult patients with community-acquired pneumonia: according to Japanese Respiratory Society guidelines Cost-effectiveness analysis of ambulatory treatment for adult patients with community-acquired pneumonia: according to Japanese Respiratory Society guidelines Morimoto T, Koyama H (...) , Shimbo T, Fukui T Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of oral antibiotics for community-acquired pneumonia for ambulatory treatment. The antibiotics compared were amoxicillin-clavulanate (AMX-CVA, 1,500 mg/day

2002 NHS Economic Evaluation Database.

538. Cost-effectiveness of IV-to-oral switch therapy: azithromycin vs cefuroxime with or without erythromycin for the treatment of community-acquired pneumonia

Cost-effectiveness of IV-to-oral switch therapy: azithromycin vs cefuroxime with or without erythromycin for the treatment of community-acquired pneumonia Cost-effectiveness of IV-to-oral switch therapy: azithromycin vs cefuroxime with or without erythromycin for the treatment of community-acquired pneumonia Cost-effectiveness of IV-to-oral switch therapy: azithromycin vs cefuroxime with or without erythromycin for the treatment of community-acquired pneumonia Paladino J A, Gudgel L D, Forrest (...) A, Niederman M S Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Two alternative strategies for treating patients with community-acquired pneumonia (CAP) were examined. One strategy was intravenous (IV) to oral azithromycin (AZI

2002 NHS Economic Evaluation Database.

539. Ventilator-associated pneumonia and upper airway colonisation with Gram negative bacilli: the role of stress ulcer prophylaxis in children

Ventilator-associated pneumonia and upper airway colonisation with Gram negative bacilli: the role of stress ulcer prophylaxis in children PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2002 PedsCCM Evidence-Based Journal Club

540. Chest physiotherapy for the prevention of ventilator-associated pneumonia

Chest physiotherapy for the prevention of ventilator-associated pneumonia PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2002 PedsCCM Evidence-Based Journal Club