Latest & greatest articles for pregnancy

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Top results for pregnancy

1. Prescription of macrolides vs penicillin during pregnancy was linked to major malformations in offspring. (Abstract)

Prescription of macrolides vs penicillin during pregnancy was linked to major malformations in offspring. Fan H, Gilbert R, O'Callaghan F, Li L. Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study. BMJ. 2020;368:m331. 32075790.

2020 Annals of Internal Medicine

2. Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study. Full Text available with Trip Pro

in pregnancy was 4.9 (95% confidence interval 4.5 to 5.4) per 1000 maternities. 233 (56%) pregnant women admitted to hospital with SARS-CoV-2 infection in pregnancy were from black or other ethnic minority groups, 281 (69%) were overweight or obese, 175 (41%) were aged 35 or over, and 145 (34%) had pre-existing comorbidities. 266 (62%) women gave birth or had a pregnancy loss; 196 (73%) gave birth at term. Forty one (10%) women admitted to hospital needed respiratory support, and five (1%) women died (...) . Twelve (5%) of 265 infants tested positive for SARS-CoV-2 RNA, six of them within the first 12 hours after birth.Most pregnant women admitted to hospital with SARS-CoV-2 infection were in the late second or third trimester, supporting guidance for continued social distancing measures in later pregnancy. Most had good outcomes, and transmission of SARS-CoV-2 to infants was uncommon. The high proportion of women from black or minority ethnic groups admitted with infection needs urgent investigation

2020 BMJ

3. Cardiovascular Considerations in Caring for Pregnant Patients: A Scientific Statement From the American Heart Association Full Text available with Trip Pro

, and significant aortic dilatation with underlying connective tissue disease. Women with these conditions are often advised to avoid pregnancy. However, it is not uncommon for women to present pregnant, and at that point, the high-risk cardio-obstetrics team must work together to come up with the best way to mitigate maternal cardiovascular and obstetric risk and fetal risk moving forward. Medical Conditions During Pregnancy Hypertensive Disorders in Pregnancy Hypertensive disorders of pregnancy (HDP (...) treatment before pregnancy. Current treatment options for pregnant women with familial hypercholesterolemia include bile acid sequestrants, which lack systemic circulation, and, as last resort, low-density lipoprotein apheresis in severe cases ( ). , Ischemic Heart Disease in Pregnancy Ischemic heart disease during pregnancy constitutes a rare but potentially fatal condition. The risk of acute myocardial infarction (MI) is 3- to 4-fold higher in pregnant women compared with their nonpregnant

2020 American Heart Association

4. Management of Genital Herpes in Pregnancy

Management of Genital Herpes in Pregnancy Management of Genital Herpes in Pregnancy | ACOG Clinical Guidance Journals & Publications Patient Education Topics Featured Clinical Topics Hi, Featured Clinical Topics Clinical Guidance Management of Genital Herpes in Pregnancy Practice Bulletin Number 220 May 2020 Jump to Resources Share By reading this page you agree to ACOG's Terms and Conditions. . Because many women of childbearing age are infected or will be infected with HSV, the risk (...) of maternal transmission of this virus to the fetus or newborn is a major health concern. This document has been revised to include that for women with a primary or nonprimary first-episode genital HSV infection during the third trimester of pregnancy, cesarean delivery may be offered due to the possibility of prolonged viral shedding. Log in to read more This content is only available to members and subscribers. Nonmembers: Subscribe now to access exclusive ACOG Clinical content, including: ACOG Clinical

2020 American College of Obstetricians and Gynecologists

5. Thyroid Disease in Pregnancy

Thyroid Disease in Pregnancy Thyroid Disease in Pregnancy | ACOG Clinical Guidance Journals & Publications Patient Education Topics Featured Clinical Topics Hi, Featured Clinical Topics Clinical Guidance Thyroid Disease in Pregnancy Practice Bulletin Number 223 June 2020 Jump to Resources Share By reading this page you agree to ACOG's Terms and Conditions. Nonmembers: Subscribe now to access exclusive ACOG Clinical content, including: ACOG Clinical is designed for easy and convenient access (...) and clinical management issues. Note for Life Fellows: Annual membership dues are waived but there is a discounted annual subscription fee of $95 for access to publications such as the Green Journal, Practice Bulletins, and Committee Opinions. Individual subscriptions include print and online access. . Jump to: Figures & Tables Figure 1. Clinical Algorithm for Management of Thyroid Disease in Pregnancy. Abbreviations: T 3 , triiodothyronine; T 4 , thyroxine; TRAB, thyroid receptor antibodies; TSH, thyroid

2020 American College of Obstetricians and Gynecologists

6. Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease

in the context of Ebola virus disease 3 Executive summary The Democratic Republic of Congo is currently experiencing the second largest Ebola outbreak in history (1), following a 2014-2016 outbreak in western Africa that had an estimated 28,000 cases. Investigational treatment and vaccination trials are ongoing, but data in the context of pregnancy and breastfeeding are limited (2,3). A paucity of scientific evidence exists on how to best treat pregnant or breastfeed - ing women with suspected or confirmed (...) work with pregnant or breastfeeding women in the context of Ebola. The guidelines are relevant to the WHO goal of ensuring one billion people are better protected from health emergen- cies by impacting maternal mortality, neonatal survival, and the transmission Ebola virus in the context of an Ebola epidemic. Specific recommendations cover 6 topics. These are: (i) the management of acute EVD in pregnant women, (ii) the management of pregnancies in women who develop EVD during pregnancy and those

2020 World Health Organisation Guidelines

7. Maternal cardiovascular risk after hypertensive disorder of pregnancy

Maternal cardiovascular risk after hypertensive disorder of pregnancy Maternal Cardiovascular Risk After Hypertensive Disorder of Pregnancy - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library of Medicine National Center for Biotechnology Information Show account info Close Account Logged (...) Actions . 2020 May 13;heartjnl-2020-316541. doi: 10.1136/heartjnl-2020-316541. Online ahead of print. Maternal Cardiovascular Risk After Hypertensive Disorder of Pregnancy , , , , , , , , Affiliations Expand Affiliations 1 Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia. 2 Cardiometabolic, George Institute for Global Health, Sydney, New South Wales, Australia. 3 Sydney Medical School, University of Sydney, Sydney, NSW, Australia. 4 Medicine, University of New South Wales

2020 EvidenceUpdates

8. A systematic scoping review of COVID-19 during pregnancy and childbirth Full Text available with Trip Pro

, and one neonatal death. Conclusion: COVID-19 infection during pregnancy probably has a clinical presentation and severity resembling that in non-pregnant adults. It is probably not associated with poor maternal or perinatal outcomes. Keywords: COVID-19; Childbirth; Coronavirus; Neonate; Pregnancy; Systematic scoping review. © 2020 International Federation of Gynecology and Obstetrics. Similar articles Smith V, Seo D, Warty R, Payne O, Salih M, Chin KL, Ofori-Asenso R, Krishnan S, da Silva Costa F (...) A systematic scoping review of COVID-19 during pregnancy and childbirth A Systematic Scoping Review of COVID-19 During Pregnancy and Childbirth - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library of Medicine National Center for Biotechnology Information Show account info Close Account

2020 EvidenceUpdates

9. Tobacco and Nicotine Cessation During Pregnancy

), and non-Hispanic American Indian or Alaska Native women (16.7%) . Pregnant women should be advised of the significant perinatal risks associated with tobacco use, including orofacial clefts, fetal growth restriction, placenta previa, abruptio placentae, preterm prelabor rupture of membranes , low birth weight, increased perinatal mortality , ectopic pregnancy , and decreased maternal thyroid function . An estimated 5–8% of preterm deliveries, 13–19% of term infants with low birth weight, 22–34% cases (...) , and provide behavioral interventions for those who smoke . The U.S. Public Health Service recommends that clinicians offer effective tobacco cessation interventions to pregnant women who smoke at the initial prenatal visit and throughout the course of pregnancy . Addiction to and dependence on cigarettes is physiologic and psychologic, and cessation techniques should include psychosocial interventions and pharmacologic therapy. Two counseling techniques with positive effects on smoking and nicotine

2020 American College of Obstetricians and Gynecologists

10. Venous thromboembolism (VTE) prophylaxis in pregnancy and the puerperium

deterioration of pregnant patients 8 • Use standard administration forms for prophylactic and therapeutic medications (e.g. Heparin intravenous infusion order and administration form) 20,21 o For Dalteparin, write the brand name in addition to the generic name to reduce ambiguity 22 Queensland Clinical Guideline: VTE prophylaxis in pregnancy and the puerperium Refer to online version, destroy printed copies after use Page 10 of 25 2 Risk assessment Failure to recognise and/or treat personal or pregnancy (...) and the puerperium Refer to online version, destroy printed copies after use Page 12 of 25 2.3 Criteria for assessment of risk Consider the potential for additive effects of multiple risk factors. Refer to Appendix B Adjusted odds ratio (AOR) for risk of VTE. Table 5. Criteria for assessment of risk Risk assessment Antenatal criteria Postnatal criteria All risk • All pregnant women are at increased risk for VTE • All postnatal women are at increased risk for VTE Therapeutic anticoagulation • Pre-pregnancy

2020 Queensland Health

11. Management of Tick Bites and Lyme Disease During Pregnancy

terms and keywords including Lyme Disease, Pregnancy, Pregnant Women, Pregnancy Complications, Ehrlichiosis, Anaplasmosis, Rocky Mountain Spotted Fever, Babesiosis, Tularemia, Powassan Virus, Encephalitis Viruses, Tick-Borne, Tick-Borne Diseases, Colorado Tick Fever, Q Fever, Relapsing Fever, and Southern Tick-Associated Rash Illness. All articles on Lyme disease and other tick-borne diseases with a target population of pregnant women were included; other groups and populations were excluded (...) -based insect repellents: safety implications for children and pregnant and lactating women. CMAJ. 2003; 169 : 209-212 McGready R Hamilton KA Simpson JA et al. Safety of the insect repellent N,N-diethyl-M-toluamide (DEET) in pregnancy. Am J Trop Med Hyg. 2001; 65 : 285-289 Onyett H Canadian Paediatric Society Infectious Dieases and Immunization Committee Preventing mosquito and tick bites: a Canadian update. Paediatr Child Health. 2014; 19 : 326-332 Article Info Publication History Published online

2020 Society of Obstetricians and Gynaecologists of Canada

12. Valproate Pregnancy Prevention Programme: temporary advice for management during coronavirus (COVID-19)

Valproate Pregnancy Prevention Programme: temporary advice for management during coronavirus (COVID-19) Valproate Pregnancy Prevention Programme: temporary advice for management during coronavirus (COVID-19) - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance and support Valproate (...) Pregnancy Prevention Programme: temporary advice for management during coronavirus (COVID-19) Guidance has been published to support initiation of valproate in female patients and for annual review and pregnancy testing during the coronavirus pandemic. Published 21 May 2020 From: Therapeutic area: , Contents Temporary guidance for specialists Valproate is harmful if used in pregnancy. Children exposed to valproate in utero have a very high risk for congenital malformations (10% risk

2020 MHRA Drug Safety Update

13. Immunomodulatory drugs and pregnancy prevention: temporary advice for management during coronavirus (COVID-19)

Immunomodulatory drugs and pregnancy prevention: temporary advice for management during coronavirus (COVID-19) Immunomodulatory drugs and pregnancy prevention: temporary advice for management during coronavirus (COVID-19) - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance (...) and support Immunomodulatory drugs and pregnancy prevention: temporary advice for management during coronavirus (COVID-19) Guidance has been published about thalidomide, lenalidomide, and pomalidomide and the use of remote consultations and home pregnancy testing for patients taking them during COVID-19. Published 21 May 2020 From: Therapeutic area: , Contents Temporary guidance Thalidomide (Thalidomide Celgene), lenalidomide (Revlimid) and pomalidomide (Imnovid) are teratogenic immunomodulatory drugs

2020 MHRA Drug Safety Update

14. Antispasmodics during pregnancy

Antispasmodics during pregnancy Prescrire IN ENGLISH - Spotlight ''In the June issue of Prescrire International: Antispasmodics during pregnancy, in brief '', 1 June 2020 {1} {1} {1} | | > > > In the June issue of Prescrire International: Antispasmodics during pregnancy, in brief Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight In the June issue (...) of Prescrire International: Antispasmodics during pregnancy, in brief FREE DOWNLOAD Various drugs termed antispasmodics are offered to treat pain of gastrointestinal, urinary or gynaecological origin, often despite unconvincing evaluation. What are the risks to the mother and the unborn child when taken during pregnancy? Full article available for free download. In practice There is a high degree of uncertainty regarding the risks to the unborn child of taking antispasmodics during pregnancy. Given

2020 Prescrire

15. A telehealth lifestyle intervention to reduce excess gestational weight gain in pregnant women with overweight or obesity (GLOW): a randomised, parallel-group, controlled trial

A telehealth lifestyle intervention to reduce excess gestational weight gain in pregnant women with overweight or obesity (GLOW): a randomised, parallel-group, controlled trial A Telehealth Lifestyle Intervention to Reduce Excess Gestational Weight Gain in Pregnant Women With Overweight or Obesity (GLOW): A Randomised, Parallel-Group, Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search (...) Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Lancet Diabetes Endocrinol Actions . 2020 Jun;8(6):490-500. doi: 10.1016/S2213-8587(20)30107-8. A Telehealth Lifestyle Intervention to Reduce Excess Gestational Weight Gain in Pregnant Women With Overweight or Obesity (GLOW): A Randomised, Parallel-Group, Controlled Trial

2020 EvidenceUpdates

16. Complications and outcomes of SARS-CoV-2 in pregnancy: where and what is the evidence?

of Medical & Dental Sciences, University of Birmingham , Birmingham, UK. PMID: 32456489 DOI: Item in Clipboard Full-text links Cite Abstract Objectives: To add to the growing evidence on SARS-CoV-2 infection during pregnancy, so as to better inform clinical decision making and optimize patient outcomes. Methods: A systematic search of relevant databases was perfomed on 25 March 2020 and a repeat search, on 10 April 2020. Reports of pregnant patients with SARS-CoV-2 infection at any time during (...) their pregnancy were reviewed and summarized . Results: We summarized the outcomes of a total of 155 pregnant women and 118 neonates. The evidence suggests a similar rate of severe COVID-19 cases in pregnant women and the general population. The frequency of cesarean deliveries is high, against guidelines recommendations. Conclusion: Limited data on COVID-19 during preganacy, associated with a wide variation in the methodology make accurate data interpretation difficult. Keywords: SARS-CoV-2; perinatal

2020 EvidenceUpdates

17. Covid-19 and pregnancy. (Abstract)

Covid-19 and pregnancy. Guideline: Coronavirus (COVID-19) Infection in pregnancyPublished by the Royal College of Obstetricians and Gynaecologists (RCOG), with input from the Royal College of Midwives, the Royal College of Paediatrics and Child Health (RCPH), the Royal College of Anaesthetists, and the Obstetric Anaesthetists' Association.This summary is based on version 8 of the guideline, published on 17 April 2020 (https://www.rcog.org.uk/globalassets/documents/guidelines/2020-04-17

2020 BMJ

18. WHO recommendation on Calcium supplementation before pregnancy for the prevention of pre-eclampsia and its complications

to pregnancy. The cost-effectiveness of this intervention is not known. Remarks • The GDG noted that in 2018 WHO revalidated the recommendation that in populations with low dietary calcium intake, daily calcium supplementation (1.5–2.0 g oral elemental calcium) is recommended for pregnant women to reduce the risk of pre-eclampsia (1). However, there is insufficient evidence to determine with precision at what gestational age calcium supplementation should be commenced in order to confer this benefit (...) of their enjoyment of sexual and reproductive health and rights, and living a life of dignity (4). The World Health Organization (WHO) envisions a world where “every pregnant woman and newborn receives quality care throughout the pregnancy, childbirth and the postnatal period” (5). There is evidence that effective interventions exist at reasonable cost for the prevention or treatment of virtually all life-threatening maternal complications (6). Almost two thirds of the global maternal and neonatal disease burden

2020 World Health Organisation Guidelines

19. Advice for pregnant members of the anaesthesia and intensive care workforce during the COVID-19 pandemic

Advice for pregnant members of the anaesthesia and intensive care workforce during the COVID-19 pandemic 1 Occupational health advice for employers and pregnant women during the COVID-19 pandemic Version 3: Published Tuesday 21 April 2020 COVID-19 virus infection and pregnancy2 Updates Please note that version 1 of this occupational health guidance was published as a chapter in the RCOG’s general Coronavirus (COVID-19) Infection in Pregnancy guidance. The occupational health guidance will now (...) professionals on employment rights. Such information can be obtained from trade unions or from charities. In particular, relevant information about employment rights for pregnant healthcare workers is available from the RCM. This guidance aims to provide employers and pregnant women with information and available clinical evidence on the risks of continuing to work during the COVID-19 pandemic. 2. Available information about risks of contracting COVID-19 in pregnancy COVID-19 poses a risk to all members

2020 ICM Anaesthesia COVID-19

20. National Clinical Guideline on stratification of clinical risk in pregnancy

National Clinical Guideline on stratification of clinical risk in pregnancy National Clinical Guideline on stratification of clinical risk in pregnancy | HIQA Header Tasks Menu COVID-19 HIQA’s is supporting the National Public Health Emergency Team in its response to COVID-19. Read all our . National Clinical Guideline on stratification of clinical risk in pregnancy Search Search Main navigation Contact Us 021 240 9300 Follow Us Receive SMS News Alerts Text HIQA to 51155 to subscribe to our

2020 HIQA Guidelines