Latest & greatest articles for pregnancy

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on pregnancy or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on pregnancy and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for pregnancy

2021. Effectiveness of prevention programs for adolescent pregnancy: a meta-analysis.

Effectiveness of prevention programs for adolescent pregnancy: a meta-analysis. Effectiveness of prevention programs for adolescent pregnancy: a meta-analysis. Effectiveness of prevention programs for adolescent pregnancy: a meta-analysis. Franklin C, Grant D, Corcoran J, O'Dell Miller P, Bultman L Authors' objectives To assess the effectiveness of primary pregnancy prevention programmes in influencing sexual activity, contraceptive use and pregnancy rates in adolescents. Searching The Social (...) Sciences Index, PsycLIT, ERIC, MEDLINE and CINAHL were searched through 1995. Generally only peer-reviewed refereed journal articles were eligible, but five studies included in a previous review of pregnancy prevention were also included. Study selection Study designs of evaluations included in the review Only studies that presented sufficient data for a meta-analysis were eligible. Randomised controlled trials (RCTs), quasi-experimental studies with controls, pre-test post-test studies, and post-test

1997 DARE.

2022. Cost-effectiveness of treatment for drug-abusing pregnant women

. Bibliographic details Svikis D S, Golden A S, Huggins G R, Pickens R W, McCaul M E, Velez M L, Rosendale C T, Brooner R K, Gazaway P M, Stitzer M L, Ball C E. Cost-effectiveness of treatment for drug-abusing pregnant women. Advanced Drug Delivery Reviews 1997; 45(1-2): 105-113 Indexing Status Subject indexing assigned by NLM MeSH Adult; Apgar Score; Cost-Benefit Analysis; Female; Humans; Infant, Newborn; Intensive Care Units, Neonatal /economics; Pregnancy; Pregnancy Complications /psychology /economics (...) Cost-effectiveness of treatment for drug-abusing pregnant women Cost-effectiveness of treatment for drug-abusing pregnant women Cost-effectiveness of treatment for drug-abusing pregnant women Svikis D S, Golden A S, Huggins G R, Pickens R W, McCaul M E, Velez M L, Rosendale C T, Brooner R K, Gazaway P M, Stitzer M L, Ball C E Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods

1997 NHS Economic Evaluation Database.

2023. Is this patient pregnant: can you reliably rule in or rule out early pregnancy by clinical examination?

Is this patient pregnant: can you reliably rule in or rule out early pregnancy by clinical examination? Is this patient pregnant: can you reliably rule in or rule out early pregnancy by clinical examination? Is this patient pregnant: can you reliably rule in or rule out early pregnancy by clinical examination? Bastian L A, Piscitelli J T Authors' objectives To determine the value of patient history or physical examination features in determining the probability of early pregnancy. Searching (...) . Implications of the review for practice and research Practice: The authors state that, when diagnosing pregnancy, the patient or clinician should not rely on symptoms, signs of pregnancy or a home pregnancy test - a laboratory test should be requested. Research: The authors make no recommendations for further research. Bibliographic details Bastian L A, Piscitelli J T. Is this patient pregnant: can you reliably rule in or rule out early pregnancy by clinical examination? JAMA 1997; 278(7): 586-591 PubMedID

1997 DARE.

2024. Umbilical artery Doppler velocimetry in unselected and low risk pregnancies: a review of randomised controlled trials

Umbilical artery Doppler velocimetry in unselected and low risk pregnancies: a review of randomised controlled trials Umbilical artery Doppler velocimetry in unselected and low risk pregnancies: a review of randomised controlled trials Umbilical artery Doppler velocimetry in unselected and low risk pregnancies: a review of randomised controlled trials Goffinet F, Paris-Llado J, Nisand I, Breart G Authors' objectives To evaluate the effect of routine use of the umbilical Doppler in unselected (...) or low-risk pregnancies. Searching The register of trials held by the Cochrane Database of Systematic Reviews (Pregnancy and Childbirth Group) was consulted. Reference lists were scanned and the MEDLINE database was consulted. The years for which the databases were searched are not stated. Study selection Study designs of evaluations included in the review Full trial reports of completed randomised controlled trials (RCTs) of the use of at least one Doppler test after 24 weeks of gestation were

1997 DARE.

2025. Medical abortion in early pregnancy: a review of the evidence

Medical abortion in early pregnancy: a review of the evidence Medical abortion in early pregnancy: a review of the evidence Medical abortion in early pregnancy: a review of the evidence Grimes D A Authors' objectives To review the efficacy, safety and side-effects of medical abortion in early pregnancy. Searching MEDLINE was searched from 1980 for reports published in English or French using the keywords 'mifepristone', 'methotrexate' and 'early abortion'; in addition, MEDLINE was searched (...) of both methotrexate and misoprostol to cause birth defects in failed attempt abortion is unknown. Bibliographic details Grimes D A. Medical abortion in early pregnancy: a review of the evidence. Obstetrics and Gynecology 1997; 89(5 Part 1): 790-796 PubMedID Other publications of related interest U.S. Preventive Services Task Force. Guide to clinical preventive services. 2nd ed. Baltimore (MD): Williams & Wilkins; 1995. Indexing Status Subject indexing assigned by NLM MeSH Abortifacient Agents

1997 DARE.

2026. Pregnancy outcome following first trimester exposure to antihistamines: meta-analysis

Pregnancy outcome following first trimester exposure to antihistamines: meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

1997 DARE.

2027. Clinical and financial analyses of ectopic pregnancy management at a large health plan

attempting pregnancy was 18 out of 36 (laparotomy), 31 out of 58 (laparoscopy), and 7 out of 13 (MTX). Of those attempting pregnancy, 66%, 77%, and 57%, respectively, achieved intrauterine pregnancy (p=0.422 for laparoscopy versus laparotomy). The rate of tubal pregnancy was 17%, 7%, and 0%, respectively (p=0.321 for laparoscopy versus laparotomy). Finally, the rate of 'not pregnant' cases was 17% (laparotomy), 16% (laparoscopy), and 43% (MTX). The rate of complications was 13.9%, 10.3%, and 7.7% (1/13 (...) Clinical and financial analyses of ectopic pregnancy management at a large health plan Clinical and financial analyses of ectopic pregnancy management at a large health plan Clinical and financial analyses of ectopic pregnancy management at a large health plan Hidlebaugh D, O'Mara P Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed

1997 NHS Economic Evaluation Database.

2028. An economic evaluation of laparoscopy and open surgery in the treatment of tubal pregnancy

An economic evaluation of laparoscopy and open surgery in the treatment of tubal pregnancy An economic evaluation of laparoscopy and open surgery in the treatment of tubal pregnancy An economic evaluation of laparoscopy and open surgery in the treatment of tubal pregnancy Mol B W, Hajenius P J, Engelsbel S, Ankum W M, van der Veen F, Hemrika D J, Bossuyt P M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Laparoscopic surgery and open surgery in the treatment of tubal pregnancy. Type of intervention Treatment. Economic study type Cost-effectiveness analysis (cost-minimisation analysis). Study population The study population was all patients who underwent primary surgical treatment for tubal pregnancy in the study

1997 NHS Economic Evaluation Database.

2029. Is conservative surgery for tubal pregnancy preferable to salpingectomy? An economic analysis

Is conservative surgery for tubal pregnancy preferable to salpingectomy? An economic analysis Is conservative surgery for tubal pregnancy preferable to salpingectomy? An economic analysis Is conservative surgery for tubal pregnancy preferable to salpingectomy? An economic analysis Mol B W, Hajenius P J, Engelsbel S, Ankum W M, Hemrika D J, Vanderveen F, Bossuyt P M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of conservative surgery, compared with salpingectomy, for the treatment of tubal pregnancy. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The population comprised consecutive women who underwent laparoscopic surgery for tubal pregnancy. Patients

1997 NHS Economic Evaluation Database.

2030. Cost-effectiveness of strategies used in the evaluation of pregnancies complicated by elevated maternal serum alpha-fetoprotein levels

Cost-effectiveness of strategies used in the evaluation of pregnancies complicated by elevated maternal serum alpha-fetoprotein levels Cost-effectiveness of strategies used in the evaluation of pregnancies complicated by elevated maternal serum alpha-fetoprotein levels Cost-effectiveness of strategies used in the evaluation of pregnancies complicated by elevated maternal serum alpha-fetoprotein levels Nadel A S, Norton M E, Wilkins-Haug L Record Status This is a critical abstract of an economic (...) evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Strategies used in the evaluation of pregnancies with elevated maternal serum alpha-protein levels viz, targeted ultrasound and amniocentesis. Type of intervention Diagnosis. Economic study type Cost-effectiveness analysis. Study population

1997 NHS Economic Evaluation Database.

2031. Use of Gen-Probe AccuProbe Group B streptococcus test to detect group B streptococci in broth cultures of vaginal-anorectal specimens from pregnant women: comparison with traditional culture method

Use of Gen-Probe AccuProbe Group B streptococcus test to detect group B streptococci in broth cultures of vaginal-anorectal specimens from pregnant women: comparison with traditional culture method Use of Gen-Probe AccuProbe Group B streptococcus test to detect group B streptococci in broth cultures of vaginal-anorectal specimens from pregnant women: comparison with traditional culture method Use of Gen-Probe AccuProbe Group B streptococcus test to detect group B streptococci in broth cultures (...) of vaginal-anorectal specimens from pregnant women: comparison with traditional culture method Bourbeau P P, Heiter B J, Figdore M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Gen-Probe AccuProbe Group B Streptococcus Culture

1997 NHS Economic Evaluation Database.

2032. Cost-minimization analysis of domiciliary antenatal fetal monitoring in high-risk pregnancies

Cost-minimization analysis of domiciliary antenatal fetal monitoring in high-risk pregnancies Cost-minimization analysis of domiciliary antenatal fetal monitoring in high-risk pregnancies Cost-minimization analysis of domiciliary antenatal fetal monitoring in high-risk pregnancies Birnie E, Monincx W M, Zondervan H A, Bossuyt P M, Bonsel G J Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief (...) summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Antenatal foetal monitoring in the home (cardiotocography and obstetric surveillance). Type of intervention Primary prevention. Economic study type Cost-effectiveness analysis. Study population Women referred to the antenatal clinic who lived near the hospital and had one or more of 15 predefined conditions for a high-risk pregnancy

1997 NHS Economic Evaluation Database.

2033. Reduction of sick leave for lumbar back and posterior pelvic pain in pregnancy

Reduction of sick leave for lumbar back and posterior pelvic pain in pregnancy Reduction of sick leave for lumbar back and posterior pelvic pain in pregnancy Reduction of sick leave for lumbar back and posterior pelvic pain in pregnancy Noren L, Ostgaard S, Nielsen T F, Ostgaard H C Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed (...) by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Using a physiotherapy consultation incorporating a differentiated, individual-based programme on sick leave during pregnancy, for women experiencing lumbar back or posterior pelvic pain. The individually designed programme starting after back pain assessment incorporated elements such as teaching the women to understand their specific situation; teaching anatomy, body posture, vocational ergonomics

1997 NHS Economic Evaluation Database.

2034. A decision analysis to guide antibiotic selection for chlamydia infection during pregnancy

A decision analysis to guide antibiotic selection for chlamydia infection during pregnancy A decision analysis to guide antibiotic selection for chlamydia infection during pregnancy A decision analysis to guide antibiotic selection for chlamydia infection during pregnancy Hueston W J, Lenhart J G Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions (...) followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Treating infection with Chlamydia trachomatis in pregnant women initially with any of 4 antibiotic options (amoxicillin, 500mg 3 times a day for 7 days; erythromycin, 500mg 4 times a day for 7 days; clindamycin hydrochloride, 450mg 4 times a day for 7 days; and azithromycin, a single 1g dose), followed, for non-responders, by 1 of 3 antibiotics not chosen for initial therapy. Type

1997 NHS Economic Evaluation Database.

2035. Preventing unintended pregnancy: the cost-effectiveness of three methods of emergency contraception

programme for publicly funded programmes. The cost analysis was based on two sets of assumptions regarding the costs of unintended births; in the first set of assumptions (averted-birth model), the full costs of unintended births, both unwanted and mistimed, were considered; while in the second set of assumptions (delayed-birth model), it was assumed that women with timing failures (69% of total unintended pregnancies) would choose to become pregnant 2 years later. The dates to which the price data (...) Preventing unintended pregnancy: the cost-effectiveness of three methods of emergency contraception Preventing unintended pregnancy: the cost-effectiveness of three methods of emergency contraception Preventing unintended pregnancy: the cost-effectiveness of three methods of emergency contraception Trussell J, Koenig J, Ellertson C, Stewart F Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief

1997 NHS Economic Evaluation Database.

2036. Should obstetricians see women with normal pregnancies? A multicentre randomised controlled trial of routine antenatal care by general practitioners and midwives compared with shared care led by obstetricians. Full Text available with Trip Pro

Should obstetricians see women with normal pregnancies? A multicentre randomised controlled trial of routine antenatal care by general practitioners and midwives compared with shared care led by obstetricians. To compare routine antenatal care provided by general practitioners and midwives with obstetrician led shared care.Multicentre randomised controlled trial.51 general practices linked to nine Scottish maternity hospitals.1765 women at low risk of antenatal complications.Routine antenatal (...) admissions (27% (222/834) v 32% (266/840), P<0.05), non-attendances (7% (57) v 11% (89), P<0.01) and daycare (12% (102) v 7% (139), P<0.05) but more were referred (49% (406) v 36% (305), P<0.0001). Rates of antenatal diagnoses did not differ except that fewer women in the general practitioner and midwife group had hypertensive disorders (pregnancy induced hypertension, 5% (37) v 8% (70), P<0.01) and fewer had labour induced (18% (149) v 24% (201), P<0.01). Few failures to comply with the care protocol

1996 BMJ Controlled trial quality: predicted high

2037. Screening for hepatitis B in pregnancy

Screening for hepatitis B in pregnancy Screening for hepatitis B in pregnancy Screening for hepatitis B in pregnancy Best L Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Best L. Screening for hepatitis B in pregnancy. Southampton: Wessex Institute for Health Research and Development (WIHRD) 1996 Authors' objectives There is a proposal (...) for all pregnant women to be screened for hepatitis B surface antigen (HBsAg) in the antenatal period. Neonates who are likely to have been infected with the hepatitis B virus (ie those with HBsAg positive mothers) can be immunised in their first 6 months of life. The author evaluates this proposal. Authors' conclusions Universal screening is strongly recommended. The author points out that there are plans to implement routine hepatitis B vaccination, and that, since vaccination would probably take

1996 Health Technology Assessment (HTA) Database.

2038. Routine ultrasound imaging in pregnancy: how evidence-based are the guidelines?

Routine ultrasound imaging in pregnancy: how evidence-based are the guidelines? Routine ultrasound imaging in pregnancy: how evidence-based are the guidelines? Routine ultrasound imaging in pregnancy: how evidence-based are the guidelines? Green CL, Hadorn D, Bassett K, Kazanjian A Record Status This is a bibliographic record of a published health technology assessment. The agency responsible for the publication has subsequently been disbanded. No evaluation of the quality of this assessment (...) has been made for the HTA database. Citation Green CL, Hadorn D, Bassett K, Kazanjian A. Routine ultrasound imaging in pregnancy: how evidence-based are the guidelines? British Columbia Office of Health Technology Assessment (BCOHTA). BCOHTA 96:2D. 1996 Authors' objectives To present a critical appraisal of evidence-based recommendations regarding routine ultrasound imaging in pregnancy. Authors' conclusions In summary, the research evidence presented by the groups reviewing routine ultrasound

1996 Health Technology Assessment (HTA) Database.

2039. Risks of occupational anaesthetic gas exposure for the pregnant woman and the fetus - systematic review

is to assist public health physicians in their decisions about risks incurred by exposed pregnant women and their fetus. Project page URL Indexing Status Subject indexing assigned by CRD MeSH Anesthetics, Inhalation; Fetus; Pregnancy Language Published English, French Country of organisation Canada Province or state Quebec Address for correspondence Conseil d'Evaluation des Technologies de la Sante du Quebec, 2021, avenue Union, #1040, Montreal, Quebec H3A S29, Canada. Tel: 514-873-2563; FAX: 514-873-1369 (...) Risks of occupational anaesthetic gas exposure for the pregnant woman and the fetus - systematic review Risks of occupational anaesthetic gas exposure for the pregnant woman and the fetus - systematic review Risks of occupational anaesthetic gas exposure for the pregnant woman and the fetus - systematic review Conseil d'Evaluation des Technologies de la Sante du Quebec Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation

1996 Health Technology Assessment (HTA) Database.

2040. Acyclovir prophylaxis in late pregnancy to prevent neonatal herpes: a cost-effectiveness analysis

Acyclovir prophylaxis in late pregnancy to prevent neonatal herpes: a cost-effectiveness analysis Acyclovir prophylaxis in late pregnancy to prevent neonatal herpes: a cost-effectiveness analysis Acyclovir prophylaxis in late pregnancy to prevent neonatal herpes: a cost-effectiveness analysis Randolph A G, Hartshorn R M, Washington A E Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Antiviral (Acyclovir) prophylaxis in the prevention of neonatal herpes. Type of intervention Primary prevention. Economic study type Cost-effectiveness analysis. Study population A hypothetical cohort of 10,000 pregnant women with at least one previously documented outbreak of genital herpes. Setting Hospital. The study was conducted in the USA

1996 NHS Economic Evaluation Database.