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Effect of antenatal dietary interventions in maternal obesity on pregnancy weight-gain and birthweight: Healthy Mums and Babies (HUMBA) randomized trial Pregnancy interventions that improve maternal and infant outcomes are urgently needed in populations with high rates of obesity. We undertook the Healthy Mums and Babies (HUMBA) randomized controlled trial to assess the effect of dietary interventions and or probiotics in a multiethnic population of pregnant women with obesity, living (...) in an area of high deprivation.To determine whether a culturally tailored dietary intervention and or daily probiotic capsules in pregnant women with obesity reduces the co-primary outcomes of (1) excessive gestational weight gain (mean >0.27 kg/week) and (2) birthweight.We conducted a 2 × 2 factorial, randomized controlled trial in women without diabetes at pregnancy booking, body mass index ≥30 kg/m2, and a singleton pregnancy. At 12+0 to 17+6 weeks' gestation, eligible women were randomized
Could the YEARS algorithm be used to exclude pulmonary embolism during pregnancy? Data from the CT-PE-pregnancy study The recently proposed YEARS algorithm was shown to safely exclude pulmonary embolism (PE) and reduce the use of computed tomography pulmonary angiography (CTPA) among pregnant women with suspected PE. Our aim was to externally validate this finding.We performed a post hoc analysis of a prospective management outcome study for PE diagnosis in pregnant women. PE was diagnosed (...) levels (<1000 ng/mL in women with no items, and <500 ng/mL in women with one or more items), 77 women (21%) met the criteria for PE exclusion and would not have undergone CTPA as per the YEARS algorithm. None of these 77 women had PE diagnosed during the initial work-up or 3-month follow-up. Therefore, the failure rate of the YEARS algorithm in our pregnant women population was 0/77 (95% confidence interval 0.0-3.9).In our study, application of the YEARS algorithm would have resulted in safe
The objective of this guideline is to evaluate bacterial vaginosis in pregnancy concerning • Different treatments for prevention of preterm delivery. • Screening of pregnant women with low as well as high risk of sPTD. • Stratification into gestational ages below and above 16 weeks. • Diagnostic methods. Key words Bacterial vaginosis, vaginal pH, pH-glove, vaginal discharge, Nugent score, Amsel score, Gardnerella vaginalis, Mobiluncus species, preterm delivery, preterm birth, GRADE, clindamycin (...) , clindamycin might be used for treatment of symp- toms). • This recommendation addresses both treatment with metronidazole and clindamycin. • This recommendation addresses all gestational ages of pregnancy. Treatment with probiotics ??: We suggest against treatment of BV-positive pregnant women with probiotics in order reducing the risk of sPTD. • This recommendation addresses both women at low and high risk of sPTD. • This recommendation addresses asymptomatic as well as symptomatic women
Thrombosis prophylactic (LMWH) can be considered when proteinuria >5 g/d B 3 Renal transplant recipients Recommendations Level of evidence Recommendation Preconception Pregnancy should be postponed until: • > 1 year after kidney transplant • Pre-pregnant s-creatinine 110 bør vedligeholdelsesdosis med magnesiumsulfat halveres. Ved kreatinin>221 overvejes kun bolus Monitorering af de uræmisk metaboliske forhold, herunder hgb, D- vitamin, parathyroidea hormon, syre/base status mm. Der er risiko for blivende (...) . Klemetti MM, Laivuori H, Tikkanen M, Nuutila M, Hiilesmaa V, Teramo K. Obstetric and perinatal outcome in type 1 diabetes patients with diabetic nephropathy during 1988-2011. Diabetologia. 2015;58(4):678-686. 3. Damm JA, Asbjornsdottir B, Callesen NF, et al. Diabetic nephropathy and microalbuminuria in pregnant women with type 1 and type 2 diabetes: Prevalence, antihypertensive strategy, and pregnancy outcome. Diabetes Care. 2013;36(11):3489-3494. 4. Jensen DM, Korsholm L, Ovesen P, et al. Peri
of the pregnant woman is ultrasound, then MR and finally imaging with radiation such as CT. 3 C DSOG 2019 Urology and pregnancy Page 3 of 3 Danish version Below you find the entire Danish version of the guideline Urologiske nyresygdomme og graviditet Guidelinen er en revision af tidligere Nyresygdomme og graviditet fra 2011. Denne guideline er delt op i 2: medicinske nyresygdomme og graviditet samt urologiske sygdomme og graviditet Forfattere: Al-Saudi Noor Introlæge Slagelse Eskildsen Morten Reservelæge (...) of pregnancy: Adv Biomed Res. 2016; 5: 186. 9. Stehman-Breen, C.O., et al., Increased risk of preeclampsia among nulliparous pregnant women with idiopathic hematuria. Am J Obstet Gynecol, 2002. 187(3): p. 703-8. 10. Tapp, D.C. and J.B. Copley, Effect of red blood cell lysis on protein quantitation in hematuric states. Am J Nephrol, 1988. 8(3): p. 190-3. Billeddiagnostiske undersøgelser af den gravide kvinde. Såfremt en undersøgelse er indiceret, skal den udføres. Der er formentlig større risiko
Tobacco and pregnancy 0 Tobacco and pregnancy A national guideline from the Danish Society of Obstetrics and Gynaecology Aims • To describe the risks of adverse fetal outcomes if a pregnant woman uses tobacco products. • To describe the risks of adverse outcomes among newborn children whose mothers use tobacco products during lactation. • To suggest a strategy for screening pregnant women for use of tobacco products. • To suggest a strategy for handling women who use tobacco products during (...) pregnancy and lactation. This guideline does not deal with social aspects related to the use of tobacco products by pregnant women or their partners, and it does not deal with tobacco products as markers of use of other drugs. Recommendations Evidence level Active and passive smoking, e-cigarettes and smokeless tobacco is discouraged during pregnancy. A/B All pregnant women should be asked about smoking status, exposure to passive smoking, use of e-cigarettes and smokeless tobacco at their first contact
søgningen: Allen VM, Yudin MH, Bouchard C, Boucher M, Caddy S, Castillo E, et al.; Infectious Diseases Committee, Society of Obstetricians and Gynaecologists of Canada. Management of group B streptococcal bacteriuria in pregnancy. J Obstet Gynaecol Can 2012; 34:482–6 Referencer fra Uptodate: Karen M Puopolo, Lawrence C Madoff. Group B streptococcal infection in pregnant women. Uptodate last updated july 15, 2017 Søgt på Cochrane med følgende søgeord : asymtomatic bacteriurina in pregnancy Samt søgt (...) ]) AND ("pregnancy"[MeSH Terms] OR "pregnancy"[All Fields])) AND ("association"[MeSH Terms] OR "association"[All Fields])) AND (Clinical Trial[ptyp] AND "2008/11/29"[PDat] : "2018/11/26"[PDat] AND "humans"[MeSH Terms] AND English[lang]) Søgningen gav 2 artikler, hvoraf 1 relevant Vaccination Søgestreng Medline Udført (05.11.2018)(flyttes) (((((Pregnancy[Title/Abstract]) OR Pregnancy[MeSH Terms]) OR Pregnant[Title/Abstract])) AND (((((((Vaccine[Title/Abstract]) OR Vaccination[MeSH Terms]) OR Vaccination[Title
SMFM Special Statement, research to knowledge: promoting the training of physician-scientists in the biology of pregnancy Research to knowledge: promoting the training of physician-scientists in the biology of pregnancy - American Journal of Obstetrics & Gynecology Email/Username: Password: Remember me Search Terms Search within Search Share this page: Volume 218, Issue 1, Pages B9–B13 To read this article in full, please review your options for gaining access at the bottom of the page (...) . Research to knowledge: promoting the training of physician-scientists in the biology of pregnancy Society for Maternal-Fetal Medicine (SMFM) , x Yoel Sadovsky Affiliations Magee-Womens Research Institute, University of Pittsburgh Department of Obstetrics, Gynecology and Reproductive Sciences, Pittsburgh, Pennsylvania, USA , MD a , x Aaron B. Caughey Affiliations Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, Oregon, USA , MD, PhD b , x Michelle DiVito
involving 3725 pregnant women were included in this comparison; 19 trials were assessed as having low-to-moderate risk of bias for most domains and three trials were assessed as having high risk of bias for most domains. Supplementation with vitamin D alone during pregnancy probably reduces the risk of pre-eclampsia (risk ratio (RR) 0.48, 95% confidence interval (CI) 0.30 to 0.79; 4 trials, 499 women, moderate-certainty evidence) and gestational diabetes (RR 0.51, 95% CI 0.27 to 0.97; 4 trials, 446 (...) for maternal adverse events, no firm conclusions can be drawn.Supplementation with vitamin D and calcium versus placebo/no interventionNine trials involving 1916 pregnant women were included in this comparison; three trials were assessed as having low risk of bias for allocation and blinding, four trials were assessed as having high risk of bias and two had some components having a low risk, high risk, or unclear risk. Supplementation with vitamin D and calcium during pregnancy probably reduces the risk
2019CochraneControlled trial quality: predicted high
Screening for Hepatitis B Virus Infection in Pregnant Women: US Preventive Services Task Force Reaffirmation Recommendation Statement. Screening for hepatitis B virus (HBV) infection during pregnancy identifies women whose infants are at risk of perinatal transmission. Data from a nationally representative sample showed a prevalence of maternal HBV infection of 85.8 cases per 100 000 deliveries from 1998 to 2011 (0.09% of live-born singleton deliveries in the United States). Although (...) there are guidelines for universal infant HBV vaccination, rates of maternal HBV infection have increased annually by 5.5% since 1998. Children infected with HBV during infancy or childhood are more likely to develop chronic infection. Chronic HBV infection increases long-term morbidity and mortality by predisposing infected persons to cirrhosis of the liver and liver cancer.To update the 2009 US Preventive Services Task Force (USPSTF) recommendation on screening for HBV infection in pregnant women.The USPSTF
Health outcomes of young children born to mothers who received 2009 pandemic H1N1 influenza vaccination during pregnancy: retrospective cohort study. To determine whether any association exists between exposure to 2009 pandemic H1N1 (pH1N1) influenza vaccination during pregnancy and negative health outcomes in early childhood.Retrospective cohort study.Population based birth registry linked with health administrative databases in the province of Ontario, Canada.All live births from November (...) hazard ratio 1.05, 95% confidence interval 1.02 to 1.09) and decreased rates of gastrointestinal infections (adjusted incidence rate ratio 0.94, 0.91 to 0.98). These results were unchanged in sensitivity analyses accounting for any potential differential healthcare seeking behavior or access between exposure groups.No associations were observed between exposure to pH1N1 influenza vaccine during pregnancy and most five year pediatric health outcomes. Residual confounding may explain the small
bile acid profile, composed of primary or secondary, conjugated or non-conjugated bile acids, may provide more specific disease information.To assess and compare, independently or in combination, the diagnostic accuracy of total serum bile acids or serum bile acids profile, or both, for the diagnosis of intrahepatic cholestasis of pregnancy in pregnant women, presenting with pruritus. To define the optimal cut-off values for components of serum bile acid profile; to investigate possible sources (...) ), ProQuest Dissertations & Thesis Database, and Index to Theses in Great Britain and Ireland.Prospective or retrospective diagnostic case-control or cross-sectional studies, irrespective of publication date, format, and language, which evaluated the diagnostic accuracy of total serum bile acids (TSBA) or components of serum bile acid profile for the diagnosis of intrahepatic cholestasis of pregnancy in pregnant women of any age or ethnicity, in any clinical setting, symptomatic for pruritus.We selected
Nutritional Lifestyle Intervention in Obese Pregnant Women, Including Lower Carbohydrate Intake, Is Associated With Increased Maternal Free Fatty Acids, 3-beta-Hydroxybutyrate, and Fasting Glucose Concentrations: A Secondary Factorial Analysis of the Euro In our randomized controlled trial, we investigated the impact of healthy eating (HE) aiming for restricted gestational weight gain (GWG) and physical activity (PA) interventions on maternal and neonatal lipid metabolism.Obese pregnant women (...) of pregnancy and neonatal outcomes were analyzed using general linear models with adjustment for relevant parameters.At 24-28 weeks' gestation, FFAs (mean ± SD, 0.60 ± 0.19 vs. 0.55 ± 0.17 mmol/L, P < 0.01) were increased after adjustment for FFA at baseline, maternal age, BMI at time of examination, gestational week, insulin resistance, self-reported food intake, self-reported physical activity, and maternal smoking, and GWG was lower (3.3 ± 2.6 vs. 4.3 ± 2.8 kg, P < 0.001, adjusted mean differences -1.0
pregnancies and a short cervix remaining after a threatened preterm labor episode.This open, randomized, controlled trial was conducted in 132 pregnant women who had not delivered 48 hours after a threatened preterm labor episode and had a short cervix remaining (≤20 mm between 240 and 296 weeks and ≤10 mm between 300 and 336 weeks). Patients were randomly assigned to cervical pessary (n = 67) or routine management (n = 65). The primary outcome was the spontaneous preterm birth rate before 34 weeks (...) Cervical pessary for preventing preterm birth in twin pregnancies with maternal short cervix after an episode of threatened preterm labor: randomised controlled trial No intervention has proved effective to date in reducing the spontaneous preterm birth rate in twin pregnancies following an episode of threatened preterm labor and with a short cervix remaining. This study was designed to ascertain whether cervical pessaries are useful in preventing spontaneous preterm birth in women with twin
Self-reported Physical Health of Women Who Did and Did Not Terminate Pregnancy After Seeking Abortion Services: A Cohort Study. Research demonstrates worse short-term morbidity and mortality associated with childbirth than with abortion, but little research has examined long-term physical health in women with unwanted pregnancies after abortion versus childbirth.To examine the physical health of women who seek and receive or are denied abortion.Prospective cohort study.30 U.S. abortion