Latest & greatest articles for pressure ulcer

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This page lists the very latest high quality evidence on pressure ulcer and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for pressure ulcer

161. A randomized trial of low-air-loss beds for treatment of pressure ulcers. (Abstract)

A randomized trial of low-air-loss beds for treatment of pressure ulcers. To assess the effectiveness of low-air-loss beds for the treatment of pressure ulcers in nursing homes.Prospective, randomized, clinical trial.Three teaching nursing homes in Los Angeles, Calif.Eighty-four nursing home residents with trunk or trochanter pressure ulcers (Shea stage > or = 2).Subjects were randomly assigned to use either a low-air-loss bed (n = 43) or a 10-cm corrugated foam mattress (n = 41) throughout (...) substantial improvement compared with foam mattresses despite other factors in pressure ulcer healing.

1993 JAMA Controlled trial quality: uncertain

162. Platelet-derived growth factor BB for the treatment of chronic pressure ulcers. (Abstract)

Platelet-derived growth factor BB for the treatment of chronic pressure ulcers. A randomised, phase I/II, double-blind, placebo-controlled study was designed to assess the effect of topically applied recombinant human BB homodimeric platelet-derived growth factor (rPDGF-BB) on healing of chronic pressure ulcers. Twenty patients were randomly allocated daily treatment for 28 days with 1, 10, or 100 micrograms/ml rPDGF-BB (0.01, 0.1, or 1.0 micrograms per cm2 ulcer area) or placebo. Patients (...) treated with 100 micrograms/ml rPDGF-BB showed a greater healing response than the placebo group, but the lower doses had little effect. After 28 days, ulcers treated with 100 micrograms/ml rPDGF-BB were smaller than those treated with placebo (mean [SE] volume 6.4 [4.0] vs 21.8 [5.6]% of day 0 volume). There were no toxic effects. These preliminary findings suggest that rPDGF-BB is a potent wound-healing agent in soft tissue.

1992 Lancet Controlled trial quality: uncertain