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Latest & greatest articles for pulmonary embolism
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on pulmonary embolism or other clinical topics then use Trip today.
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Prognostic significance of deep vein thrombosis in patients presenting with acute symptomatic pulmonaryembolism Concomitant deep vein thrombosis (DVT) in patients with acute pulmonaryembolism (PE) has an uncertain prognostic significance.In a cohort of patients with PE, this study compared the risk of death in those with and those without concomitant DVT.We conducted a prospective cohort study of outpatients diagnosed with a first episode of acute symptomatic PE. Patients underwent bilateral
Gadolinium-enhanced magnetic resonance angiography for pulmonaryembolism: a multicenter prospective study (PIOPED III). The accuracy of gadolinium-enhanced magnetic resonance pulmonary angiography and magnetic resonance venography for diagnosing pulmonaryembolism has not been determined conclusively.To investigate performance characteristics of magnetic resonance angiography, with or without magnetic resonance venography, for diagnosing pulmonary embolism.Prospective, multicenter study from (...) 10 April 2006 to 30 September 2008.7 hospitals and their emergency services.371 adults with diagnosed or excluded pulmonary embolism.Sensitivity, specificity, and likelihood ratios were measured by comparing independently read magnetic resonance imaging with the reference standard for diagnosing pulmonaryembolism. Reference standard diagnosis or exclusion was made by using various tests, including computed tomographic angiography and venography, ventilation-perfusion lung scan, venous
Accuracy of very low pretest probability estimates for pulmonaryembolism using the method of attribute matching compared with the wells score Attribute matching matches an explicit clinical profile of a patient to a reference database to estimate the numeric value for the pretest probability of an acute disease. The authors tested the accuracy of this method for forecasting a very low probability of venous thromboembolism (VTE) in symptomatic emergency department (ED) patients.The authors (...) performed a secondary analysis of five data sets from 15 hospitals in three countries. All patients had data collected at the time of clinical evaluation for suspected pulmonaryembolism (PE). The criterion standard to exclude VTE required no evidence of PE or deep venous thrombosis (DVT) within 45 days of enrollment. To estimate pretest probabilities, a computer program selected, from a large reference database of patients previously evaluated for PE, patients who matched 10 predictor variables
Potential of an age adjusted D-dimer cut-off value to improve the exclusion of pulmonaryembolism in older patients: a retrospective analysis of three large cohorts. In older patients, the the D-dimer test for pulmonaryembolism has reduced specificity and is therefore less useful. In this study a new, age dependent cut-off value for the test was devised and its usefulness with older patients assessed.Retrospective multicentre cohort study.General and teaching hospitals in Belgium, France (...) , the Netherlands, and Switzerland. Patients 5132 consecutive patients with clinically suspected pulmonary embolism.Development of a new D-dimer cut-off point in patients aged >50 years in a derivation set (data from two multicentre cohort studies), based on receiver operating characteristics (ROC) curves. This cut-off value was then validated with two independent validation datasets.The proportion of patients in the validation cohorts with a negative D-dimer test, the proportion in whom pulmonaryembolism
Vena caval filters for the prevention of pulmonaryembolism. Pulmonary emboli (PE) can have potentially fatal consequences. Inferior vena caval filters (VCFs) are metal alloy devices that mechanically trap fragmented thromboemboli from the deep leg veins en route to the pulmonary circulation. Filters are designed to be introduced (and in the case of retrievable filters, removed) percutaneously. Although their deployment seems of theoretical benefit, their clinical efficacy and adverse event (...) profile is unclear.This is an update of a Cochrane review first published in 2007.To examine evidence for the effectiveness of VCFs in preventing pulmonaryembolism (PE). Secondary outcomes were mortality, distal (to filter) thrombosis, and filter-related complications.The Cochrane Peripheral Vascular Diseases Group searched their Specialised Register (last searched October 2009) and the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library 2009, Issue 4 for randomised
Safety of excluding acute pulmonaryembolism based on an unlikely clinical probability by the Wells rule and normal D-dimer concentration: a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
Natriuretic peptides and troponins in pulmonaryembolism: a meta-analysis The role of biomarkers such as B-type natriuretic peptides (BNP and NT-proBNP) and troponins in risk stratification of acute pulmonaryembolism (APE) is still debated. A meta-analysis was performed to assess the association between raised natriuretic peptide levels, alone or in conjunction with troponins, and all-cause and APE-related mortality, serious adverse events and echographic right ventricular dysfunction.MEDLINE
Troponin-based risk stratification of patients with acute nonmassive pulmonaryembolism: systematic review and metaanalysis Controversy exists regarding the usefulness of troponin testing for the risk stratification of patients with acute pulmonaryembolism (PE). We conducted an updated systematic review and a metaanalysis of troponin-based risk stratification of normotensive patients with acute symptomatic PE. The sources of our data were publications listed in Medline and Embase from 1980
Pulmonaryembolism in pregnancy. Pulmonaryembolism (PE) is the leading cause of maternal mortality in the developed world. Mortality from PE in pregnancy might be related to challenges in targeting the right population for prevention, ensuring that diagnosis is suspected and adequately investigated, and initiating timely and best possible treatment of this disease. Pregnancy is an example of Virchow's triad: hypercoagulability, venous stasis, and vascular damage; together these factors lead
Thrombolysis Compared With Heparin for the Initial Treatment of PulmonaryEmbolism: A Meta-Analysis of the Randomized Controlled Trials PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?
Thrombolysis for patients with pulmonaryembolism, right ventricular dysfunction or pulmonary hypertension, and normal blood pressure Home - Monash Health Find a Location Latest news Victorian Minister for Health Jenny Mikakos MP meets a patient and researcher leading the world-first safety trial examining stem cells as therapy for acute stroke. Your health Heat kills more people than any natural disaster. Be prepared and survive the heat this summer. Our children’s hospital Monash Children’s
VIDAS D-dimer in combination with clinical pre-test probability to rule out pulmonaryembolism: a systematic review of management outcome studies VIDAS D-dimer in combination with clinical pre-test probability to rule out pulmonaryembolism: a systematic review of management outcome studies VIDAS D-dimer in combination with clinical pre-test probability to rule out pulmonaryembolism: a systematic review of management outcome studies Carrier M, Righini M, Karami Djurabi R, Huisman MV, Perrier (...) A, Wells PS, Rodger M, Wuillemin WA, Le Gal G CRD summary This review assessed the combined negative VIDAS D-dimer result and a non-high pre-test probability to exclude pulmonaryembolism. The authors concluded that this method can safely and effectively exclude pulmonaryembolism in outpatients with a suspected event. This was a largely well-conducted review, although a lack of clarity regarding study quality limited the interpretation of reliability. Authors' objectives To assess efficacy and safety
Transthoracic sonography for the detection of pulmonaryembolism: a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
Short term effect of recombinant tissue plasminogen activator in patients with hemodynamically stable acute pulmonaryembolism: results of a meta-analysis involving 464 patients Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
Safety of ruling out acute pulmonaryembolism by normal computed tomography pulmonary angiography in patients with an indication for computed tomography: systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
A meta-analysis of bed rest versus early ambulation in the management of pulmonaryembolism, deep vein thrombosis, or both Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
Catheter-directed therapy for the treatment of massive pulmonaryembolism: systematic review and meta-analysis of modern techniques Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
Outpatient treatment and early discharge of symptomatic pulmonaryembolism: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
Simplification of the revised geneva score for assessing clinical probability of pulmonaryembolism The revised Geneva score is a fully standardized clinical decision rule (CDR) in the diagnostic workup of patients with suspected pulmonaryembolism (PE). The variables of the decision rule have different weights, which could lead to miscalculations in an acute setting. We have validated a simplified version of the revised Geneva score.Data from 1049 patients from 2 large prospective diagnostic