Latest & greatest articles for sedation

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Top results for sedation

1. EM Advanced Clinical Practitioners providing safe sedation in the adult Emergency Department

EM Advanced Clinical Practitioners providing safe sedation in the adult Emergency Department Emergency Medicine Advanced Clinical Practitioners (EM-ACPs) providing safe sedation in the adult Emergency Department (30 November 2020) Patron: HRH Princess Royal 7-9 Bream’s Buildings Tel +44 (0)20 7404 1999 London Fax +44 (0)20 7067 1267 EC4A 1DT www.rcem.ac.uk Position Statement Emergency Medicine Advanced Clinical Practitioners (EM-ACPs) providing safe sedation in the adult Emergency Department (...) . 30 November 2020 Scope This document explains the reasoning behind EM-ACPs being supported to provide safe sedation of adult patients within Emergency Departments (EDs), including regarding how to develop and maintain safe sedation practice by their EM-ACP workforce. Reason for Development The EM-ACP role is an essential component of the Emergency Medicine workforce * . A qualified ACP will be expected to work at Tier 3 level ** and will provide care to patients in all areas of the ED. An EM-ACP

2020 Royal College of Emergency Medicine

2. General Versus Local Anesthesia With Conscious Sedation in Transcatheter Aortic Valve Implantation: The Randomized SOLVE-TAVI Trial

General Versus Local Anesthesia With Conscious Sedation in Transcatheter Aortic Valve Implantation: The Randomized SOLVE-TAVI Trial General Versus Local Anesthesia With Conscious Sedation in Transcatheter Aortic Valve Implantation: The Randomized SOLVE-TAVI Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 (...) /CIRCULATIONAHA.120.046451. Epub 2020 Aug 21. General Versus Local Anesthesia With Conscious Sedation in Transcatheter Aortic Valve Implantation: The Randomized SOLVE-TAVI Trial , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Heart Center Leipzig at University of Leipzig, Germany (H.T., H.-J.F., G.S., P.H., P.L., M.A.-W., M.S., D.H., M.B., J.E., S.D.). 2 Leipzig Heart Institute, Germany (H.T., H.-J.F., G.S., P.H., P.L., M.A.-W., M.S., D.H., M.B., J.E

2020 EvidenceUpdates

3. A Single Prophylactic Dose of Ondansetron Given at Cessation of Postoperative Propofol Sedation Decreases Postoperative Nausea and Vomiting in Cardiac Surgery Patients: A Randomized Controlled Trial

A Single Prophylactic Dose of Ondansetron Given at Cessation of Postoperative Propofol Sedation Decreases Postoperative Nausea and Vomiting in Cardiac Surgery Patients: A Randomized Controlled Trial A Single Prophylactic Dose of Ondansetron Given at Cessation of Postoperative Propofol Sedation Decreases Postoperative Nausea and Vomiting in Cardiac Surgery Patients: A Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage (...) Display options Format Share Permalink Copy Page navigation Randomized Controlled Trial Anesth Analg Actions . 2020 Oct;131(4):1164-1172. doi: 10.1213/ANE.0000000000004730. A Single Prophylactic Dose of Ondansetron Given at Cessation of Postoperative Propofol Sedation Decreases Postoperative Nausea and Vomiting in Cardiac Surgery Patients: A Randomized Controlled Trial , , , , , , Affiliations Expand Affiliations 1 From the Pharmacy Department, St Paul's Hospital, Providence Health Care, Vancouver

2020 EvidenceUpdates

4. AnaConDa-S for sedation with volatile anaesthetics in intensive care

AnaConDa-S for sedation with volatile anaesthetics in intensive care AnaConDa-S for sedation with volatile anaesthetics in intensive care Medtech innovation briefing Published: 6 October 2020 www.nice.org.uk/guidance/mib229 pathways Summary Summary • The technology technology described in this briefing is AnaConDa-S. It is a volatile anaesthetic delivery system for use with ventilators to allow people to be sedated using inhaled anaesthetics (isoflurane or sevoflurane). • The innovative aspects (...) innovative aspects are that it enables sedation to be done using inhaled anaesthetics with standard ventilators in intensive care settings, instead of needing intravenous (IV) anaesthesia. • The intended place in therapy place in therapy would be as an alternative to IV sedation of people who need invasive ventilation in an intensive care setting. • The main points from the evidence main points from the evidence summarised in this briefing are from 5 studies, including 1 meta-analysis, with a total

2020 National Institute for Health and Clinical Excellence - Advice

5. Anaesthesia and sedation in breastfeeding women

Anaesthesia and sedation in breastfeeding women Guidelines Anaesthesia and sedation in breastfeeding women 2020 June 2020Guidelines Guidelineonanaesthesiaandsedationinbreastfeeding women2020 GuidelinefromtheAssociationofAnaesthetists J.Mitchell, 1 W.Jones, 2 E.Winkley 3 andS.M.Kinsella 4 1Consultant,DepartmentofAnaesthesia,UniversityHospitalAyr,Ayr,UK 2SpecialistPharmacist,BreastfeedingandMedication,Portsmouth,UK 3Consultant,DepartmentofAnaesthesia,NorthumbriaNHSFoundationTrust,UK 4Consultant (...) ,DepartmentofAnaesthesia,StMichael’sHospital,Bristol,UK Summary Breastfeedinghasmanyhealthbene?tsforthemotherandinfant.Womenwhoarebreastfeedingmayrequire anaesthesia or sedation. Concerns regarding the passage of drugs into breast milk may lead to inconsistent advicefromprofessionals.Thiscansometimesresultintheinterruptionoffeedingfor24 hoursorlongerafter anaesthesia, or expressing and discarding (‘pumping and dumping’) breast milk; this may contribute to early cessationofbreastfeeding.However

2020 Association of Anaesthetists of GB and Ireland

6. Remimazolam (Byfavo) - For sedation

Remimazolam (Byfavo) - For sedation Drug Approval Package: BYFAVO U.S. Department of Health and Human Services Search FDA Submit search Drug Approval Package: BYFAVO Company: Cosmo Technologies, Ltd. Application Number: 212295 Approval Date: 07/02/2020 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. FDA Approval Letter and Labeling (PDF) (PDF) FDA Application Review Files (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF

2020 FDA - Drug Approval Package

7. Capnography for Moderate Sedation in Non-Anesthesia Settings

Capnography for Moderate Sedation in Non-Anesthesia Settings Management Briefs eBrief-no172 -- Capnography for Moderate Sedation in Non-Anesthesia Settings Talk to the Veterans Crisis Line now An official website of the United States government Here's how you know The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. The site is secure. The https:// ensures that you're connecting (...) to the official website and that any information you provide is encrypted and sent securely. Search Search the ORD website Button to search HSRD Contact us TTY: 711 × We're here anytime, day or night — 24/7 If you are a Veteran in crisis or concerned about one, connect with our caring, qualified responders for confidential help. Many of them are Veterans themselves. Get more resources at . » » » Management Briefs eBrief-no172 -- Capnography for Moderate Sedation in Non-Anesthesia Settings Health Services

2020 Veterans Affairs - R&D

8. CIRSE Standards of Practice on Analgesia and Sedation for Interventional Radiology in Adults

CIRSE Standards of Practice on Analgesia and Sedation for Interventional Radiology in Adults CIRSE Standards of Practice on Analgesia and Sedation for Interventional Radiology in Adults | SpringerLink Search Search SpringerLink Search CIRSE Standards of Practice on Analgesia and Sedation for Interventional Radiology in Adults , , , , , , , , & ( 2020 ) 136 Accesses Abstract This CIRSE Standards of Practice document provides best practices for the safe administration of procedural sedation (...) and analgesia for interventional radiology procedures in adults. The document is aimed at health professionals involved in the provision of sedation and analgesia during interventional radiology procedures. The document has been developed by a writing group consisting of physicians with internationally recognised expertise in interventional radiology, and analgesia and sedation. This is a preview of subscription content, to check access. Access options References 1. Green SM, Krauss B. Procedural sedation

2020 Cardiovascular and Interventional Radiological Society of Europe

9. Evidence Brief: Capnography for Moderate Sedation in Non-Anesthesia Settings

Evidence Brief: Capnography for Moderate Sedation in Non-Anesthesia Settings ? June 2020 Evidence Brief: Capnography for Moderate Sedation in Non-Anesthesia Settings Prepared for: Department of Veterans Affairs Veterans Health Administration Health Services Research & Development Service Washington, DC 20420 Prepared by: Evidence Synthesis Program (ESP) Coordinating Center Portland VA Health Care System Portland, OR Mark Helfand, MD, MPH, MS, Director Authors: Stephanie Veazie, MPH Kathryn Vela (...) , MLIS Katherine Mackey, MD, MPP Evidence Synthesis Program Evidence Brief: Capnography for Moderate Sedation Evidence Synthesis Program i PREFACE The VA Evidence Synthesis Program (ESP) was established in 2007 to provide timely and accurate syntheses of targeted healthcare topics of importance to clinicians, managers, and policymakers as they work to improve the health and healthcare of Veterans. These reports help: • Develop clinical policies informed by evidence; • Implement effective services

2020 Veterans Affairs Evidence-based Synthesis Program Reports

10. Is ketamine sedation without local anesthesia sufficient for pediatric laceration repair? A double-blind randomized clinical trial

Is ketamine sedation without local anesthesia sufficient for pediatric laceration repair? A double-blind randomized clinical trial Is Ketamine Sedation Without Local Anesthesia Sufficient for Pediatric Laceration Repair? A Double-Blind Randomized Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes (...) Share Permalink Copy Page navigation Am J Emerg Med Actions . 2020 Mar 19;S0735-6757(20)30172-8. doi: 10.1016/j.ajem.2020.03.030. Online ahead of print. Is Ketamine Sedation Without Local Anesthesia Sufficient for Pediatric Laceration Repair? A Double-Blind Randomized Clinical Trial , , , Affiliations Expand Affiliations 1 Department of Emergency Medicine, Seoul National University Bundang Hospital, Gyeonggi-do, Republic of Korea. 2 Department of Emergency Medicine, Seoul National University Bundang

2020 EvidenceUpdates

11. COVID-19: Sedation-Ventilation Liberation of COVID Patients

COVID-19: Sedation-Ventilation Liberation of COVID Patients COVID-19: SEDATION-VENTILATION LIBERATION OF COVID+ PATIENTS A Rapid Guidance Summary from the Penn Medicine Center for Evidence-based Practice Last updated May 6, 2020 12:00 pm All links rechecked April 27 th unless otherwise noted. Key questions answered in this summary • How should sedatives be dosed? • What fluid resuscitation approach should be taken with ventilated patients? • How often should spontaneous breathing tests (...) be attempted? • What are the criteria to begin a spontaneous breathing test? • What is the protocol for a spontaneous breathing test? Summary of major recommendations • Minimizing continuous sedation and instead favoring bolused sedation to targeted endpoints reduces number of days of mechanical ventilation. • Patients with ARDS should receive minimal fluid resuscitation. • Ventilator weaning tests should be attempted daily upon improvement of respiratory status. • Ventilator weaning protocol should follow

2020 Centre for Evidence-Based Practice, Penn Medicine

12. Ketamine Procedural Sedation for Children in EDs

Ketamine Procedural Sedation for Children in EDs The Royal College of Emergency Medicine Best Practice Guideline KETAMINE PROCEDURAL SEDATION FOR CHILDREN IN THE EMERGENCY DEPARTMENT Revised: February 2020 Ketamine Procedural Sedation for Children in The Emergency Department (Feb 2020) 15 Summary of recommendations 1. Ketamine sedation may be appropriate for a procedure that is painful, or frightening after all other options have been considered. 2. Ketamine should not be used for sedation (...) in the Emergency Department for children under the age of 1 year. Ketamine should be only be used by clinicians with significant relevant experience in the use of ketamine when performing procedural sedation in children aged between 2-5 years. 3. Ketamine sedation should take place in an area with full resuscitation facilities immediately available. 4. Safe sedation requires adequate senior medical and nursing cover in the Emergency Department when any sedation takes place. 5. Ketamine sedation requires

2020 Royal College of Emergency Medicine

13. Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients. Full Text available with Trip Pro

Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients. In critically ill, mechanically ventilated patients, daily interruption of sedation has been shown to reduce the time on ventilation and the length of stay in the intensive care unit (ICU). Data on whether a plan of no sedation, as compared with a plan of light sedation, has an effect on mortality are lacking.In a multicenter, randomized, controlled trial, we assigned, in a 1:1 ratio, mechanically ventilated ICU (...) patients to a plan of no sedation (nonsedation group) or to a plan of light sedation (i.e., to a level at which the patient was arousable, defined as a score of -2 to -3 on the Richmond Agitation and Sedation Scale [RASS], on which scores range from -5 [unresponsive] to +4 [combative]) (sedation group) with daily interruption. The primary outcome was mortality at 90 days. Secondary outcomes were the number of major thromboembolic events, the number of days free from coma or delirium, acute kidney

2020 NEJM

14. Impact of Timing of Preprocedural Opioids on Adverse Events in Procedural Sedation (Abstract)

Impact of Timing of Preprocedural Opioids on Adverse Events in Procedural Sedation The risk of respiratory depression is increased when opioids are added to sedative agents. In our recent multicenter emergency department (ED) procedural sedation cohort, we reported a strong association between preprocedural opioids and sedation-related adverse events. We sought to examine the association between timing of opioids and the incidence of adverse sedation outcomes.We conducted a secondary analysis (...) of a prospective cohort of children aged 0 to 18 years who received sedation for a painful procedure in six Canadian pediatric EDs from July 2010 to February 2015. The primary risk factor was timing of opioid administration, adjusted for age, opioid type, preprocedural and sedation medications, and procedure type. Outcomes were 1) oxygen desaturation, 2) vomiting, and 3) positive pressure ventilation (PPV).Of the 6,295 children in the original cohort, 1,806 (29%) received a preprocedural opioid. Patients

2020 EvidenceUpdates

15. Comparison of Intraoperative Sedation With Dexmedetomidine Versus Propofol on Acute Postoperative Pain in Total Knee Arthroplasty Under Spinal Anesthesia: A Randomized Trial (Abstract)

Comparison of Intraoperative Sedation With Dexmedetomidine Versus Propofol on Acute Postoperative Pain in Total Knee Arthroplasty Under Spinal Anesthesia: A Randomized Trial In patients undergoing total knee arthroplasty under spinal anesthesia, we compared the postoperative analgesic effect of intraoperative sedation with dexmedetomidine versus propofol. We hypothesized that sedation with dexmedetomidine would result in lower postoperative opioid analgesic consumption than with propofol.Forty (...) -eight patients were enrolled and randomly assigned to either a dexmedetomidine group (n = 24), which received a loading dose of 1 μg/kg dexmedetomidine over 10 minutes, followed by a continuous infusion of 0.1-0.5 μg·kg·hour, or a propofol group (n = 24), which received a continuous infusion of propofol via a target-controlled infusion to maintain the effect-site concentration within a range of 0.5-2.0 μg/mL. The drug infusion rate was determined according to the sedation level, targeting a modified

2020 EvidenceUpdates

16. Oral Ondansetron to Reduce Vomiting in Children Receiving Intranasal Fentanyl and Inhaled Nitrous Oxide for Procedural Sedation and Analgesia: A Randomized Controlled Trial (Abstract)

Oral Ondansetron to Reduce Vomiting in Children Receiving Intranasal Fentanyl and Inhaled Nitrous Oxide for Procedural Sedation and Analgesia: A Randomized Controlled Trial Intranasal fentanyl and inhaled nitrous oxide are increasingly combined to provide procedural sedation and analgesia in the pediatric emergency setting. This regimen is attractive because of its nonparenteral administration, but is associated with a higher incidence of vomiting than nitrous oxide alone. We seek to assess (...) whether prophylactic oral ondansetron use could reduce the incidence of vomiting associated with intranasal fentanyl and nitrous oxide for procedural sedation compared with placebo.This was a double-blind, randomized controlled trial of oral ondansetron versus placebo conducted at a single tertiary care pediatric emergency department. Children aged 3 to 18 years with planned sedation with intranasal fentanyl and nitrous oxide were randomized to receive oral ondansetron or placebo 30 to 60 minutes

2020 EvidenceUpdates

17. During Conscious Sedation the Risk of Adverse Events Is Likely Increased in Obese Children Compared to Those of Healthy Weight

During Conscious Sedation the Risk of Adverse Events Is Likely Increased in Obese Children Compared to Those of Healthy Weight UTCAT3394, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title During Conscious Sedation the Risk of Adverse Events Is Likely Increased in Obese Children Compared to Those of Healthy Weight Clinical Question Are obese children undergoing conscious sedation at increased risk for adverse events (...) compared to children who are at healthy weight? Clinical Bottom Line For children with childhood obesity, conscious sedation may lead to more adverse events including oxyhemoglobin desaturation, nausea and true apnea. However, additional evidence is needed to know if there is any clinical and statistical difference between obese children and healthy weight children during conscious sedation. This is supported by both a cross-sectional retrospective study and a review of literature on the relationship

2019 UTHSCSA Dental School CAT Library

18. Early Sedation with Dexmedetomidine in Critically Ill Patients. Full Text available with Trip Pro

Early Sedation with Dexmedetomidine in Critically Ill Patients. Dexmedetomidine produces sedation while maintaining a degree of arousability and may reduce the duration of mechanical ventilation and delirium among patients in the intensive care unit (ICU). The use of dexmedetomidine as the sole or primary sedative agent in patients undergoing mechanical ventilation has not been extensively studied.In an open-label, randomized trial, we enrolled critically ill adults who had been undergoing (...) ventilation for less than 12 hours in the ICU and were expected to continue to receive ventilatory support for longer than the next calendar day to receive dexmedetomidine as the sole or primary sedative or to receive usual care (propofol, midazolam, or other sedatives). The target range of sedation-scores on the Richmond Agitation and Sedation Scale (which is scored from -5 [unresponsive] to +4 [combative]) was -2 to +1 (lightly sedated to restless). The primary outcome was the rate of death from any

2019 NEJM Controlled trial quality: predicted high

19. Guidelines for Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures

Guidelines for Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures Guidelines for Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures | From the American Academy of Pediatrics | Pediatrics '); document.write(''); } function OAS_AD(pos) { if (OAS_version >= 11 && typeof(OAS_RICH)!='undefined') { OAS_RICH(pos); } else { OAS_NORMAL(pos); } } //--> Search (...) for this keyword Source User menu Sections Sign up for highlighting editor-chosen studies with the greatest impact on clinical care. From the American Academy of Pediatrics Guidelines for Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures Charles J. Coté , Stephen Wilson , AMERICAN ACADEMY OF PEDIATRICS , AMERICAN ACADEMY OF PEDIATRIC DENTISTRY Abstract The safe sedation of children for procedures requires a systematic approach

2019 American Academy of Pediatrics

20. Is the Level of Sedation Depth in the Early Postintubation Period Associated With Worse Patient Outcomes? Full Text available with Trip Pro

Is the Level of Sedation Depth in the Early Postintubation Period Associated With Worse Patient Outcomes? Is the Level of Sedation Depth in the Early Postintubation Period Associated With Worse Patient Outcomes? - Annals of Emergency Medicine Email/Username: Password: Remember me Search Terms Search within Search Share this page Access provided by Volume 73, Issue 5, Pages 488–490 Is the Level of Sedation Depth in the Early Postintubation Period Associated With Worse Patient Outcomes? x Michael (...) Gottlieb , MD (EBEM Commentator) , x Keya A. Patel , MD (EBEM Commentator) , x William G. McDowell , MD (EBEM Commentator) Department of Emergency Medicine, Rush University Medical Center, Chicago, IL DOI: | Publication History Published online: December 20, 2018 Expand all Collapse all Article Outline Take-Home Message Compared with deep sedation, light sedation early in the postintubation course is associated with reduced mortality, decreased length of ICU stay, and fewer days of mechanical

2019 Annals of Emergency Medicine Systematic Review Snapshots