Latest & greatest articles for side effects

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on side effects or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on side effects and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for side effects

21. Improving symptoms and side effects in older patients with schizophrenia with decreasing dopamine D2/3 receptor occupancy following risperidone and olanzapine dose reduction

Improving symptoms and side effects in older patients with schizophrenia with decreasing dopamine D2/3 receptor occupancy following risperidone and olanzapine dose reduction Improving symptoms and side effects in older patients with schizophrenia with decreasing dopamine D2/3 receptor occupancy following risperidone and olanzapine dose reduction | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie (...) settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Improving symptoms and side effects

2015 Evidence-Based Mental Health

22. Effects of vertical and side-alternating vibration training on fall risk factors and bone turnover in older people at risk of falls Full Text available with Trip Pro

Effects of vertical and side-alternating vibration training on fall risk factors and bone turnover in older people at risk of falls whole-body vibration training may improve neuromuscular function, falls risk and bone density, but previous studies have had conflicting findings.this study aimed to evaluate the influence of vertical vibration (VV) and side-alternating vibration (SV) on musculoskeletal health in older people at risk of falls.single-blind, randomised, controlled trial comparing

2014 EvidenceUpdates Controlled trial quality: uncertain

23. [Lactobacillus rhamnosus GG supplementation to reduce side-effects of anti-Helicobacter pylori treatment]. (Abstract)

[Lactobacillus rhamnosus GG supplementation to reduce side-effects of anti-Helicobacter pylori treatment]. Helicobacter pylori (Hp) eradication fails in about 10% of patients because of the occurrence of resistance to antibiotics and side-effects. During anti H.pylori therapy, probiotics have been used to reduce the incidence of side-effects.To determine whether adding the probiotic Lactobacillus rhamhousus GG to an anti-H. pylori regimen could help to prevent or minimize the gastrointestinal (...) side-effect burden.66 subjects screening positive for H. pylori infection (male/female: 45/21, mean age 56,6 DS ± 16,7 year ), 59 subjects receiving 7 days of Omeprazole 20 mg b.i.d, Amoxicillin 1000 mg b.i.d and Clarithromycin 500 mg b.i.d were randomly assigned to Lactobacillus rhamnosus GG (6 x 9 ufc b.i.d ) (n = 29) or placebo (n = 30). Patients completed questionnaires after the treatment to determine the type and 10 severity of side-effects.Side effects occurred mainly during the eradication

2014 Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Controlled trial quality: uncertain

24. [Lactobacillus rhamnosus GG supplementation to reduce side-effects of anti-Helicobacter pylori treatment]. (Abstract)

[Lactobacillus rhamnosus GG supplementation to reduce side-effects of anti-Helicobacter pylori treatment]. Helicobacter pylori (Hp) eradication fails in about 10% of patients because of the occurrence of resistance to antibiotics and side-effects. During anti H.pylori therapy, probiotics have been used to reduce the incidence of side-effects.To determine whether adding the probiotic Lactobacillus rhamhousus GG to an anti-H. pylori regimen could help to prevent or minimize the gastrointestinal (...) side-effect burden.66 subjects screening positive for H. pylori infection (male/female: 45/21, mean age 56,6 DS ± 16,7 year ), 59 subjects receiving 7 days of Omeprazole 20 mg b.i.d, Amoxicillin 1000 mg b.i.d and Clarithromycin 500 mg b.i.d were randomly assigned to Lactobacillus rhamnosus GG (6 x 9 ufc b.i.d ) (n = 29) or placebo (n = 30). Patients completed questionnaires after the treatment to determine the type and 10 severity of side-effects.Side effects occurred mainly during the eradication

2014 Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Controlled trial quality: uncertain

25. This asthma treatment has a lasting side effect in children

This asthma treatment has a lasting side effect in children This asthma treatment has a lasting side effect in children Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics This asthma treatment has a lasting side effect in children View/ Open Date 2013-09 Format Metadata Abstract Before prescribing inhaled corticosteroids (...) (ICS) for a child with asthma, tell the patient -- and parents -- that their use could lead to a small but permanent effect on adult height. Stength of recommendation: B: Based on one prospective study. URI Part of Citation Journal of Family Practice, 62(9) 2013: 500-502. Rights OpenAccess. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. Collections hosted by hosted by

2014 PURLS

26. Statins have no side effects? What our study really found, its fixable flaws, and why trials transparency matters (again).

Statins have no side effects? What our study really found, its fixable flaws, and why trials transparency matters (again). Statins have no side effects? What our study really found, its fixable flaws, and why trials transparency matters (again). – Bad Science Search TED Talk Collected Journalism This Nerdy Book This Great Book T-shirts Categories (3) (4) (6) (45) (28) (6) (16) (190) (5) (20) (52) (88) (2) (1) (2) (1) (677) (4) (14) (2) (37) (4) (9) (3) (11) (6) (3) (16) (13) (1) (6) (8) (6) (6 (...) ) (12) (1) (59) (2) (6) (34) (26) (1) (1) (1) (2) (2) (1) (52) (7) (2) (1) (2) (3) (1) (1) (1) (4) (2) (82) (1) (10) (6) (3) (2) (1) (5) (1) (10) (1) (2) (1) (1) (6) (4) (3) (2) (52) (3) (18) (10) (1) March 13th, 2014 by Ben Goldacre in , , | Hi there, sorry to be absent (dayjob!). I was surprised to see a study I’m a co-author on getting some today, under the headline “Statins ‘have no side effects'”. That’s not what found. But it was an interesting piece of work, with an odd result, looking

2014 Bad Science

27. Paliperidone depot is not different from haloperidol in relapse prevention of schizophrenia, but different side effects should be considered

Paliperidone depot is not different from haloperidol in relapse prevention of schizophrenia, but different side effects should be considered Paliperidone depot is not different from haloperidol in relapse prevention of schizophrenia, but different side effects should be considered | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use (...) side effects should be considered Article Text Pharmacological interventions Paliperidone depot is not different from haloperidol in relapse prevention of schizophrenia, but different side effects should be considered Oliver Freudenreich Statistics from Altmetric.com What is already known on this topic? Reducing the occurrence of relapse in schizophrenia is an important treatment goal. Antipsychotics are effective in reducing relapse rates but they are often not taken regularly because of poor

2014 Evidence-Based Mental Health

28. Randomised controlled trial: Citalopram decreases agitation in the context of Alzheimer's disease, but at doses higher than those commonly prescribed and at the expense of side effects

Randomised controlled trial: Citalopram decreases agitation in the context of Alzheimer's disease, but at doses higher than those commonly prescribed and at the expense of side effects Citalopram decreases agitation in the context of Alzheimer's disease, but at doses higher than those commonly prescribed and at the expense of side effects | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via (...) of Alzheimer's disease, but at doses higher than those commonly prescribed and at the expense of side effects Article Text Therapeutics Randomised controlled trial Citalopram decreases agitation in the context of Alzheimer's disease, but at doses higher than those commonly prescribed and at the expense of side effects Benjamin R Underwood 1 , Chris Fox 2 Statistics from Altmetric.com Commentary on: Porsteinsson AP , Drye LT , Pollock BG , et al . Effect of citalopram on agitation in Alzheimer disease

2014 Evidence-Based Medicine

29. Domperidone: risks of cardiac side effects

Domperidone: risks of cardiac side effects Domperidone: risks of cardiac side effects - GOV.UK GOV.UK uses cookies to make the site simpler. or Search Domperidone: risks of cardiac side effects Indication restricted to nausea and vomiting, new contraindications, and reduced dose and duration of use. Published 11 December 2014 From: Therapeutic area: , Article date: May 2014 Domperidone is a dopamine antagonist with antiemetic properties. A European review assessed the benefits and risks (...) of domperidone following continued reports of cardiac side effects. The review confirmed a small increased risk of serious cardiac side effects. A higher risk was observed particularly in people older than 60 years, people taking daily oral domperidone doses of more than 30 mg, and those taking QT-prolonging medicines or CYP3A4 inhibitors at the same time as domperidone. For indications other than nausea and vomiting, the benefits were not considered to outweigh the cardiac risk. Based on the results

2014 MHRA Drug Safety Update

30. Ivabradine (Procoralan) in the symptomatic treatment of angina: risk of cardiac side effects

Ivabradine (Procoralan) in the symptomatic treatment of angina: risk of cardiac side effects Ivabradine (Procoralan) in the symptomatic treatment of angina: risk of cardiac side effects - GOV.UK GOV.UK uses cookies to make the site simpler. or Search Ivabradine (Procoralan) in the symptomatic treatment of angina: risk of cardiac side effects New advice to minimise risk Published 19 December 2014 From: Therapeutic area: Ivabradine (Procoralan) is used to treat chronic heart failure

2014 MHRA Drug Safety Update

31. Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis. Full Text available with Trip Pro

Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis. Methotrexate (MTX) is a disease modifying antirheumatic drug (DMARD) used as a first line agent for treating rheumatoid arthritis (RA). Pharmacologically, it is classified as an antimetabolite due to its antagonistic effect on folic acid metabolism. Many patients treated with MTX experience mucosal, gastrointestinal, hepatic or haematologic side effects. Supplementation with folic (...) or folinic acid during treatment with MTX may ameliorate these side effects.To identify trials of supplementation with folic acid or folinic acid during MTX therapy for rheumatoid arthritis and to assess the benefits and harms of folic acid and folinic acid (a) in reducing the mucosal, gastrointestinal (GI), hepatic and haematologic side effects of MTX, and (b) whether or not folic or folinic acid supplementation has any effect on MTX benefit.We originally performed MEDLINE searches, from January 1966

2013 Cochrane

32. Antipsychotic drugs and extrapyramidal side effects in first episode psychosis: a systematic review of head-head comparisons

Antipsychotic drugs and extrapyramidal side effects in first episode psychosis: a systematic review of head-head comparisons Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2013 DARE.

33. Systematic review with meta-analysis: Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS Full Text available with Trip Pro

Systematic review with meta-analysis: Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie (...) relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS Article Text Therapeutics Systematic review with meta-analysis Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS Andrew Östör , Pippa A Watson Statistics from Altmetric.com Commentary on: Derry S , Moore RA , Rabbie R . Topical NSAIDs for chronic musculoskeletal pain in adults

2013 Evidence-Based Medicine

34. Mefloquine: strengthened warnings on neuropsychiatric side effects

Mefloquine: strengthened warnings on neuropsychiatric side effects Mefloquine: strengthened warnings on neuropsychiatric side effects - GOV.UK GOV.UK uses cookies to make the site simpler. or Search Mefloquine: strengthened warnings on neuropsychiatric side effects A recent review of the prescribing information has led to strengthened warnings and new measures to help minimise risks. To minimise the risk of these adverse reactions, mefloquine must not be used for chemoprophylaxis in patients (...) name Lariam) is used for prophylaxis and treatment of Plasmodium falciparum malaria. Official guidance on the appropriate use of antimalarial medicines and the prevalence of resistance should be considered when prescribing mefloquine (see further information links below). Although the potential for neuropsychiatric side effects with mefloquine is a well-established risk, a recent review of the prescribing information has led to strengthened warnings and new measures to help minimise risks

2013 MHRA Drug Safety Update

35. No difference in extrapyramidal side effects between first-generation and second-generation antipsychotics

No difference in extrapyramidal side effects between first-generation and second-generation antipsychotics No difference in extrapyramidal side effects between first-generation and second-generation antipsychotics | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here No difference in extrapyramidal side effects between first-generation and second-generation antipsychotics Article Text Therapeutics No difference in extrapyramidal side effects

2012 Evidence-Based Mental Health

36. Review: extrapyramidal side effects vary between different second-generation antipsychotic drugs

Review: extrapyramidal side effects vary between different second-generation antipsychotic drugs Review: extrapyramidal side effects vary between different second-generation antipsychotic drugs | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: extrapyramidal side effects vary between different second-generation antipsychotic drugs Article Text Therapeutics Review: extrapyramidal side effects vary between different second-generation

2012 Evidence-Based Mental Health

37. Antidepressant non-adherence is common among veterans, with ineffectiveness and side effects as commonly reported reasons

Antidepressant non-adherence is common among veterans, with ineffectiveness and side effects as commonly reported reasons Antidepressant non-adherence is common among veterans, with ineffectiveness and side effects as commonly reported reasons | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using (...) your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Antidepressant non-adherence is common among veterans, with ineffectiveness and side effects as commonly reported reasons Article Text Prevalence

2011 Evidence-Based Mental Health

38. Review: metabolic side effects of second-generation antipsychotics

Review: metabolic side effects of second-generation antipsychotics Review: metabolic side effects of second-generation antipsychotics | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password (...) * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: metabolic side effects of second-generation antipsychotics Article Text Therapeutics Review: metabolic side effects of second-generation antipsychotics Statistics from Altmetric.com Question Question To what extent do second-generation

2011 Evidence-Based Mental Health

39. No differences in efficacy of atypical and typical antipsychotics in early psychosis, but side effects differ

No differences in efficacy of atypical and typical antipsychotics in early psychosis, but side effects differ No differences in efficacy of atypical and typical antipsychotics in early psychosis, but side effects differ | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here No differences in efficacy of atypical and typical antipsychotics in early psychosis, but side effects differ Article Text Therapeutics No differences in efficacy

2011 Evidence-Based Mental Health

40. Patients with cancer believed that chemotherapy had to ?hurt? or ?cause side effects? to be effective

Patients with cancer believed that chemotherapy had to ?hurt? or ?cause side effects? to be effective Patients with cancer believed that chemotherapy had to “hurt” or “cause side effects” to be effectiveCommentary | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Patients with cancer believed that chemotherapy had to “hurt” or “cause side effects” to be effectiveCommentary Article Text Qualitative Patients with cancer believed

2010 Evidence-Based Nursing