Latest & greatest articles for side effects

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Top results for side effects

41. Incisional continuous fascia iliaca block provides more effective pain relief and fewer side effects than opioids after pelvic osteotomy in children (Abstract)

Incisional continuous fascia iliaca block provides more effective pain relief and fewer side effects than opioids after pelvic osteotomy in children Intravenous opioid therapy is frequently used for postoperative pain management in children after orthopedic surgery but causes side effects such as respiratory depression, vomiting, sedation, and urinary retention. To investigate whether a continuous incisional fascia iliaca compartment (FIC) block provides more effective postoperative pain relief (...) with fewer side effects than IV morphine, we performed a prospective, double-blind, randomized study to compare both techniques.Thirty children (ASA physical status I-II) aged 3 mo to 6 yr undergoing a pelvic osteotomy were included in the study. The children were randomized for either morphine IV and placebo (saline) via a FIC catheter (Group M) or placebo (saline) IV and ropivacaine via a FIC catheter (Group R). All patients received general anesthesia using inhaled sevoflurane and IV fentanyl

2010 EvidenceUpdates Controlled trial quality: predicted high

42. Ocular side effects of Topiramate: Frequently asked questions

Ocular side effects of Topiramate: Frequently asked questions The Royal College of Ophthalmologists Ocular side effects of Topiramate- Frequently asked questions 1. What is Topiramate and when is it indicated clinically? Topiramate is a sulfamate-substituted monosaccharide derived from D-fructose. Its is used mainly as an antiepileptic drug both as mono-therapy and as an adjunct in the control of partial and primary generalised epilepsy in adults and children above the age of two 1-3 (...) collected from spontaneous reporting systems have identified one hundred and fifteen cases of ocular side effects which include acute-onset angle closure glaucoma, acute myopia, suprachoriodal effusions, peri-orbital oedema, scleritis, blepharospasm, oculogyric crisis, nystagmus and diplopia 16 . 4. Which patients develop Acute Angle Closure Glaucoma? (AACG) The mean age of occurrence of secondary AACG is 34 years with a range between 3 years and 70 years. The condition has predominantly been reported

2010 Royal College of Ophthalmologists

43. Review of the Ocular side effects of Topiramate

Review of the Ocular side effects of Topiramate RCOphth reference: 2010/PROF/122 Original document 2006 Reviewed October 2010 1 A Review of the Ocular side effects of Topiramate Author: Patrick Watts This manuscript was reviewed by Paediatric Ophthalmology Subcommittee, Royal College of Ophthalmologists Address for Correspondence: Mr Patrick Watts Department of Ophthalmology University Hospital of Wales Cardiff CF14 4XW Telephone: (+44) 2920748583 Fax: (+44) 2920748240 Keywords: Topiramate (...) , Glaucoma RCOphth reference: 2010/PROF/122 Original document 2006 Reviewed October 2010 2 Abstract Acute angle closure glaucoma and visual blurring due to induced myopia have been reported with the use of the antiepileptic drug topiramate. Various hypotheses have been put forward to explain the mechanism of the aforementioned ocular side effects. These presumed ocular side effects of topiramate have included patients treated with other drugs such as serotonin reuptake inhibitors which are also reported

2010 Royal College of Ophthalmologists

44. Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review

Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side (...) side-effects after major surgery: a systematic review. Health Technology Assessment 2010; 14(17): 1-94 Authors' conclusions Study found no strong case for routine addition of paracetamol, non-steroidal anti-inflammatory drugs or cyclo-oxygenase inhibitors to patient-controlled administered morphine to reduce morphine consumption and associated adverse effects in the 24 hours following major surgery Project page URL URL for DARE abstract INAHTA brief and checklist Indexing Status Subject indexing

2010 Health Technology Assessment (HTA) Database.

45. Side effects of methylphenidate in childhood cancer survivors: a randomized placebo-controlled trial Full Text available with Trip Pro

Side effects of methylphenidate in childhood cancer survivors: a randomized placebo-controlled trial To investigate the frequency and severity of side effects of methylphenidate among childhood survivors of acute lymphoblastic leukemia and brain tumors and identify predictors of higher adverse effect levels.Childhood cancer survivors (N = 103) identified as having attention and learning problems completed a randomized, double-blind, 3-week, home-crossover trial of placebo, low-dose (...) methylphenidate (0.3 mg/kg; 10 mg twice daily maximum) and moderate-dose methylphenidate (0.6 mg/kg; 20 mg twice daily maximum). Caregivers completed the Barkley Side Effects Rating Scale (SERS) at baseline and each week during the medication trial. Siblings of cancer survivors (N = 49) were recruited as a healthy comparison group.There was a significantly higher number and severity of symptoms endorsed on the SERS when patients were taking moderate dose compared with placebo or low dose, but not low dose

2009 EvidenceUpdates Controlled trial quality: uncertain

46. Systematic review and metaanalysis of statins for heterozygous familial hypercholesterolemia in children: evaluation of cholesterol changes and side effects

Systematic review and metaanalysis of statins for heterozygous familial hypercholesterolemia in children: evaluation of cholesterol changes and side effects Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

47. Efficacy, tolerability and side-effect profile of fluvoxamine for major depression: meta-analysis

Efficacy, tolerability and side-effect profile of fluvoxamine for major depression: meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

48. Effects and side-effects of surgery for snoring and obstructive sleep apnea: a systematic review

Effects and side-effects of surgery for snoring and obstructive sleep apnea: a systematic review Effects and side-effects of surgery for snoring and obstructive sleep apnea: a systematic review Effects and side-effects of surgery for snoring and obstructive sleep apnea: a systematic review Franklin KA, Anttila H, Axelsson S, Gislason T, Maasilta P, Myhre KI, Rehnqvist N CRD summary The review found no evidence of any effect from laser-assisted uvulopalatoplasty or radiofrequency ablation (...) on daytime sleepiness, apnoea, quality of life or snoring; uvula removal carried a high risk of persistent side effects. The authors’ conclusions may require some caution, as there were very few controlled studies (which were possibly underpowered) and findings for snoring were inconsistent. Authors' objectives To determine the benefits and side effects of surgery for snoring and obstructive sleep apnoea in adults. Searching PubMed and Cochrane Central Register of Controlled Trials (CENTRAL) were

2009 DARE.

49. The side effects of morphine and hydromorphone patient-controlled analgesia (Abstract)

The side effects of morphine and hydromorphone patient-controlled analgesia Despite "clinical lore" among health care providers that treatment with hydromorphone results in improved pain control and fewer adverse side effects, morphine continues to be the first-line medication for postoperative patient-controlled analgesia (PCA). In this study, we compared the efficacy and side-effect profiles of morphine and hydromorphone at concentrations producing equivalent drug effect measured by pain (...) score and miosis.We conducted a prospective, randomized, double-blind trial of 50 general and gynecological surgery patients. Subjects were randomly assigned to receive either morphine (1 mg/mL) or hydromorphone (0.2 mg/mL) via PCA after surgery and were followed for a period of 8 h. The primary outcome was nausea. Secondary outcome variables were pruritus, vomiting, sedation, pain report, pupillary miosis, and patient satisfaction.The side effect profile was not different between drugs

2008 EvidenceUpdates Controlled trial quality: predicted high

50. Haloperidol, risperidone and olanzapine are similarly effective for first-episode non-affective psychosis but have differing side effects Full Text available with Trip Pro

Haloperidol, risperidone and olanzapine are similarly effective for first-episode non-affective psychosis but have differing side effects Haloperidol, risperidone and olanzapine are similarly effective for first-episode non-affective psychosis but have differing side effects | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies (...) differing side effects Article Text Therapeutics Haloperidol, risperidone and olanzapine are similarly effective for first-episode non-affective psychosis but have differing side effects Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways. Copyright

2008 Evidence-Based Mental Health

51. Review: eradication therapy supplemented by probiotics increased eradication rates and reduced side effects in H pylori infection Full Text available with Trip Pro

Review: eradication therapy supplemented by probiotics increased eradication rates and reduced side effects in H pylori infection Review: eradication therapy supplemented by probiotics increased eradication rates and reduced side effects in H pylori infection | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our (...) . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: eradication therapy supplemented by probiotics increased eradication rates and reduced side effects in H pylori infection

2008 Evidence-Based Medicine

52. The Ocular Side-Effects of Vigabatrin (Sabril) Information and Guidance for Screening

The Ocular Side-Effects of Vigabatrin (Sabril) Information and Guidance for Screening The Royal College of Ophthalmologists The Ocular Side-Effects of Vigabatrin (Sabril) Information and Guidance for Screening March 2008 Scientific Department The Royal College of Ophthalmologists 17 Cornwall Terrace Regent’s Park London NW1 4QW Telephone: 020 7935 0702 Facsimile: 020 7487 4674 www.rcophth.ac.uk © The Royal College of Ophthalmologists 2008 All rights reserved For permission to reproduce any (...) of the content contained herein please contact events@rcophth.ac.uk Royal College of Ophthalmologists The Ocular Side-Effects of Vigabatrin (Sabril) Information and Guidance for Screening March 2008 Background Vigabatrin (Sabril) is an anti-epileptic drug indicated for the treatment of partial epilepsy, with or without secondary generalisation, which is not satisfactorily controlled by other drugs. It is only licensed as first-line/monotherapy for the treatment of infantile spasms (West’s syndrome). While

2008 Royal College of Ophthalmologists

53. Efficacy and side effects of cisplatin- and carboplatin-based doublet chemotherapeutic regimens versus non-platinum-based doublet chemotherapeutic regimens as first line treatment of metastatic non-small cell lung carcinoma: a systematic review of randomi

Efficacy and side effects of cisplatin- and carboplatin-based doublet chemotherapeutic regimens versus non-platinum-based doublet chemotherapeutic regimens as first line treatment of metastatic non-small cell lung carcinoma: a systematic review of randomi Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2008 DARE.

54. Review: antibiotics are effective for acute purulent rhinitis but are associated with increased gastrointestinal side effects

Review: antibiotics are effective for acute purulent rhinitis but are associated with increased gastrointestinal side effects Review: antibiotics are effective for acute purulent rhinitis but are associated with increased gastrointestinal side effects | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log (...) in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: antibiotics are effective for acute purulent rhinitis but are associated with increased gastrointestinal side effects Article Text

2008 Evidence-Based Nursing

55. Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial. Full Text available with Trip Pro

Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial. To compare the behavioural side effects associated with two commonly used antiepilepsy drugs-phenobarbital and carbamazepine-in children in Bangladesh.Prospective randomised controlled single centre trial.Specialist children's hospital in Dhaka, Bangladesh.108 children aged 2-15 with generalised tonic-clonic (n=51) or partial and secondary generalised seizures (n=57).Seizure control (...) and behavioural side effects.91 children were followed up for 12 months. Six required a change of antiepilepsy drug. Side effects were compared in 85 children. In the last quarter of the 12 month follow-up, 71 children were seizure free after one year's treatment. Thirty two in the phenobarbital group and 39 in the carbamazepine group had no seizures in 74 and 102 days after randomisation, respectively. Ten children had increased behavioural problems, which were unacceptable in four (one in the phenobarbital

2007 BMJ Controlled trial quality: uncertain

56. Hypercapnic acidosis in ARDS: A tolerated side effect or an important therapeutic modality? Full Text available with Trip Pro

Hypercapnic acidosis in ARDS: A tolerated side effect or an important therapeutic modality? Hypercapnic acidosis in ARDS: A tolerated side effect or an important therapeutic modality? | Critical Care | Full Text Advertisement Menu Search Search all BMC articles Search Menu Table of Contents and John R Hotchkiss Critical Care 2007 11 :304 © BioMed Central Ltd 2007 Published: 16 February 2007 Citation Kregenow DA, Rubenfeld GD, Hudson LD, Swenson ER. Hypercapnic acidosis and mortality in acute (...) acidosis (HA) is often thought of as a tolerated side effect of lung protective ventilation strategies. There is a growing body of experimental evidence, however, suggesting that HA may be intrinsically protective in ventilator-induced lung injury and acute lung injury (ALI) [ – ] and that buffering HA may be detrimental [ ]. Certain patient populations, such as those with cardiovascular disease or central nervous system injuries, have the potential to be harmed by HA. To date, no clinical trial has

2007 Critical Care - EBM Journal Club

57. Sword swallowing and its side effects. Full Text available with Trip Pro

Sword swallowing and its side effects. To evaluate information on the practice and associated ill effects of sword swallowing.Letters sent to sword swallowers requesting information on technique and complications.Membership lists of the Sword Swallowers' Association International.110 sword swallowers from 16 countries.We had information from 46 sword swallowers. Major complications are more likely when the swallower is distracted or swallows multiple or unusual swords or when previous injury

2006 BMJ

58. Selenium for alleviating the side effects of chemotherapy, radiotherapy and surgery in cancer patients. Full Text available with Trip Pro

Selenium for alleviating the side effects of chemotherapy, radiotherapy and surgery in cancer patients. Selenium supplements are frequently used by cancer patients. Selenium is an essential trace element and is involved in antioxidant protection and redox-regulation in humans. Several adverse effects of radiotherapy and chemotherapy in cancer patients as well as cellular processes that maintain chronic lymphoedema have been linked to oxidative cell damage in the human body. Selenium has (...) recently been investigated as a remedy against chemotherapy and radiotherapy-associated side effects as well as its effects on lymphoedema.This review assessed the effects of supplementary selenium on adverse effects of conventional radiotherapy, chemotherapy, or surgery, in oncologic patients and on quality of life or performance status during and after oncologic treatment.We searched the Cochrane Pain, Palliative & Supportive Care Trials Register, the Cochrane Database of Systematic Reviews

2006 Cochrane

59. Topical diclofenac improved pain and physical function with no systemic side effects in primary osteoarthritis of the knee Full Text available with Trip Pro

Topical diclofenac improved pain and physical function with no systemic side effects in primary osteoarthritis of the knee Topical diclofenac improved pain and physical function with no systemic side effects in primary osteoarthritis of the knee | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using (...) your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Topical diclofenac improved pain and physical function with no systemic side effects in primary osteoarthritis of the knee Article Text

2006 Evidence-Based Medicine

60. Review: clonidine is more effective than placebo for long term smoking cessation, but has side effects Full Text available with Trip Pro

Review: clonidine is more effective than placebo for long term smoking cessation, but has side effects Review: clonidine is more effective than placebo for long term smoking cessation, but has side effects | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: clonidine is more effective than placebo for long term smoking cessation, but has side effects Article Text Therapeutics Review: clonidine is more effective than placebo for long

2006 Evidence-Based Medicine