Latest & greatest articles for statin

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Top results for statin

161. Adverse events associated with individual statin treatments for cardiovascular disease: an indirect comparison meta-analysis

Adverse events associated with individual statin treatments for cardiovascular disease: an indirect comparison meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

162. Review: Perioperative statins reduce perioperative MI and AF in statin-naïve patients. (Abstract)

Review: Perioperative statins reduce perioperative MI and AF in statin-naïve patients. 22711103 2012 08 20 2013 04 17 1539-3704 156 12 2012 Jun 19 Annals of internal medicine Ann. Intern. Med. ACP Journal Club. Review: Perioperative statins reduce perioperative MI and AF in statin-naïve patients. JC6-2 10.7326/0003-4819-156-12-201206190-02002 Rodseth Reitze R McMaster University, Hamilton, Ontario, Canada. Devereaux P J PJ eng Comment Journal Article United States Ann Intern Med 0372351 0003

2012 Annals of Internal Medicine

163. Effect of Coenzyme Q10 Supplementation on Statin-Induced Myalgias (Abstract)

Effect of Coenzyme Q10 Supplementation on Statin-Induced Myalgias Coenzyme Q10 (CoQ10) deficiency has been proposed to be causal in 3-hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitor (statin)-induced myopathies. However, the clinical benefit of supplementation is unproved. The purpose of the present study was to assess the effect of CoQ10 supplementation on myalgias presumed to be caused by statins. Patients currently receiving a statin who developed new-onset myalgias in ≥ 2 (...) extremities within 60 days of initiation or a dosage increase were eligible. Patients continued statin therapy and were randomized using a matched design to either CoQ10 60 mg twice daily or matching placebo. Double-blind treatment continued for 3 months, and patients completed a 10-cm visual analog scale (VAS) and the Short-Form McGill Pain Questionnaire at baseline and at each monthly visit. The primary end point was the comparison of the VAS score at 1 month. A total of 76 patients were enrolled (40

2012 EvidenceUpdates Controlled trial quality: predicted high

164. Statins: Is It Really Time to Reassess Benefits and Risks? Full Text available with Trip Pro

Hemoglobin A 0 Hydroxymethylglutaryl-CoA Reductase Inhibitors AIM IM N Engl J Med. 2012 Aug 23;367(8):776; author reply 776 22913699 Cardiovascular Diseases prevention & control Diabetes Mellitus chemically induced Female Glycated Hemoglobin A Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors adverse effects therapeutic use Hyperglycemia chemically induced Male Risk Assessment 2012 4 27 6 0 2012 4 27 6 0 2012 5 18 6 0 ppublish 22533536 10.1056/NEJMp1203020 (...) Statins: Is It Really Time to Reassess Benefits and Risks? 22533536 2012 05 17 2017 11 16 1533-4406 366 19 2012 May 10 The New England journal of medicine N. Engl. J. Med. Statins: is it really time to reassess benefits and risks? 1752-5 10.1056/NEJMp1203020 Goldfine Allison B AB Harvard Medical School and the Section of Clinical, Behavioral, and Outcomes Research, Joslin Diabetes Center, Boston, USA. eng Journal Article 2012 04 25 United States N Engl J Med 0255562 0028-4793 0 Glycated

2012 NEJM

165. High-sensitivity C-reactive protein, statin therapy, and risks of atrial fibrillation: an exploratory analysis of the JUPITER trial Full Text available with Trip Pro

High-sensitivity C-reactive protein, statin therapy, and risks of atrial fibrillation: an exploratory analysis of the JUPITER trial Increasing evidence supports a role for inflammation in promoting atrial fibrillation (AF) and statins have anti-inflammatory effects that may be relevant for the prevention of AF. However, studies of statin therapy and incident AF have yielded mixed results and not focused on individuals with an underlying pro-inflammatory response. We studied whether high

2012 EvidenceUpdates Controlled trial quality: uncertain

166. Statins for the prevention of contrast-induced nephropathy: a systematic review and meta-analysis

Statins for the prevention of contrast-induced nephropathy: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

167. Effect of statin therapy on contrast-induced nephropathy after coronary angiography: a meta-analysis

Effect of statin therapy on contrast-induced nephropathy after coronary angiography: a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

168. Efficacy and safety of statin treatment for cardiovascular disease: a network meta-analysis of 170 255 patients from 76 randomized trials

Efficacy and safety of statin treatment for cardiovascular disease: a network meta-analysis of 170 255 patients from 76 randomized trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

169. Meta-analysis of the cardiovascular benefits of intensive lipid lowering with statins

Meta-analysis of the cardiovascular benefits of intensive lipid lowering with statins Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

170. Statins for age-related macular degeneration. Full Text available with Trip Pro

Statins for age-related macular degeneration. Age-related macular degeneration (AMD) is a progressive late onset disorder of the macula affecting central vision. Age-related macular degeneration is the leading cause of blindness in people over 65 years in industrialized countries (Congdon 2003). Recent epidemiologic, genetic and pathological evidence has shown AMD shares a number of risk factors with atherosclerosis, leading to the hypothesis that statins may exert protective effects in AMD.To (...) examine the effectiveness of statins compared with other treatments, no treatment, or placebo in delaying the onset and/or progression of AMD.We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2011, Issue 9), MEDLINE (January 1950 to September 2011), EMBASE (January 1980 to September 2011), Latin American and Caribbean Health Sciences Literature Database (LILACS) (January 1982 to September 2011), the metaRegister of Controlled Trials (mRCT

2012 Cochrane

171. Cost-effectiveness of statin therapy for primary prevention in a low-cost statin era Full Text available with Trip Pro

induced /economics /therapy; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors /adverse effects /economics /therapeutic use; Middle Aged; Models, Biological; Practice Guidelines as Topic; Risk Factors; Time Factors; United States AccessionNumber 22011001302 Date bibliographic record published 14/09/2011 Date abstract record published 02/02/2012 NHS Economic Evaluation Database (NHS EED) Produced by the Centre for Reviews and Dissemination Copyright © 2019 University of York Homepage (...) Cost-effectiveness of statin therapy for primary prevention in a low-cost statin era Cost-effectiveness of statin therapy for primary prevention in a low-cost statin era Cost-effectiveness of statin therapy for primary prevention in a low-cost statin era Lazar LD, Pletcher MJ, Coxson PG, Bibbins-Domingo K, Goldman L Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods

2012 NHS Economic Evaluation Database.

172. Pitavastatin(Alipzal, Livazo) in dyslipidemia. The eighth statin but no results on morbidity and mortality

) dyslipidemia, when re- sponse to diet and other non-pharmacologi- cal measures are inadequate. Mechanism of action and pharmacokinetics 1 This agent is a competitive HMG-CoA reduc- tase inhibitor. The bioavailability is 51% and the elimination half-life is 8.9 hours. The main metabolite is an inactive lactone derived from n Pitavastatin has not been shown to be su- perior to other compared statins in the re- duction of lipid levels. Unlike these other statins, there are no trials on mortality and morbidity (...) Pitavastatin(Alipzal, Livazo) in dyslipidemia. The eighth statin but no results on morbidity and mortality 01/2012 Pitavastatin( Alipzal ® , Livazo ® ) in dyslipidemia The eighth statin but no results on morbidity and mortality Indications 1 Pitavastatin is indicated for the reduction of el- evated total cholesterol (TC) and low density lipoprotein cholesterol (LDL-c), in adult patients with primary hypercholesterolemia, including heterozygous familial hypercholesterolemia, and combined (mixed

2012 Drug and Therapeutics Bulletin of Navarre (Spain)

173. Statins in the Media

Statins in the Media RxFiles Academic Detailing Saskatoon City Hospital. 701 Queen Street, Saskatoon, SK Canada S7K 0M7 www.RxFiles.ca Statins in The Media. What are we to make of it? Crestor Heart Attack Legal Websites, The Latest FDA Statin Warnings and Patients Declining to Take Statins. Lipitor, Crestor, Zocor, Pravacol Recently a physician sent us a fax regarding concerns over rosuvastatin Crestor being raised by U.S. law firms online and various media. The basic premise (...) is that rosuvastatin, used to prevent heart problems, may also cause them in some patients. Faced with patients bringing in such internet clippings, the question arises of how to best respond. Statin safety has been given more visibility with the association of statin use with increased diabetes risk and cognitive impairment as noted by the FDA. 1 Is there a “quick take” to help physicians and pharmacists address patient concerns regarding outcomes? For the topic of statins increasing heart risk, note

2012 RxFiles

174. Statin use in postmenopausal women is associated with an increased risk of incident diabetes mellitus

Statin use in postmenopausal women is associated with an increased risk of incident diabetes mellitus Statin use in postmenopausal women is associated with an increased risk of incident diabetes mellitus | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Statin use in postmenopausal women is associated with an increased risk of incident diabetes mellitus Article Text Aetiology Statin use in postmenopausal women is associated

2012 Evidence-Based Medicine

175. Effect of statin therapy on the progression of coronary atherosclerosis

Effect of statin therapy on the progression of coronary atherosclerosis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

176. Systematic review and meta-analysis: Intensive statin therapy, compared with moderate dose, increases risk of new onset diabetes but decreases risk of cardiovascular events

Systematic review and meta-analysis: Intensive statin therapy, compared with moderate dose, increases risk of new onset diabetes but decreases risk of cardiovascular events Intensive statin therapy, compared with moderate dose, increases risk of new onset diabetes but decreases risk of cardiovascular events | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time (...) . To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Intensive statin therapy, compared with moderate dose, increases risk of new

2012 Evidence-Based Medicine

177. Statins: risk of hyperglycaemia and diabetes

Statins: risk of hyperglycaemia and diabetes Statins: risk of hyperglycaemia and diabetes - GOV.UK GOV.UK uses cookies to make the site simpler. or Search Statins: risk of hyperglycaemia and diabetes Statin use may be associated with a level of hyperglycaemia in some patients where formal diabetes care is appropriate. Published 11 December 2014 From: Therapeutic area: Article date: January 2012 Statins are one of the most widely prescribed drug classes in Europe for lipid control (...) and cardiovascular prophylaxis, and prescribing is continuing to grow. Between 2002 and 2008 in the UK, statin prevalence has doubled for those older than 40 year and quadrupled for those older than 80 years. In 2010, a clinical trial meta-analysis reported that statin therapy overall was associated with a slightly increased risk of new onset diabetes ( Although a small risk (odds ratio 1.09 [95% However, the evidence suggests that risk depends markedly on individual risk factors. Comparison of studies across

2012 MHRA Drug Safety Update

178. Primary prevention of major cardiovascular and cerebrovascular events with statins in diabetic patients: a meta-analysis

Primary prevention of major cardiovascular and cerebrovascular events with statins in diabetic patients: a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

179. Is statin use associated with reduced mortality after pneumonia? A systematic review and meta-analysis

Is statin use associated with reduced mortality after pneumonia? A systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

180. Is statin-associated cognitive impairment clinically relevant? A narrative review and clinical recommendations Full Text available with Trip Pro

PubMedID DOI Original Paper URL Indexing Status Subject indexing assigned by NLM MeSH Blood-Brain Barrier /metabolism; Cognition /drug effects; Cognition Disorders /chemically induced /epidemiology; Humans; Hydrophobic and Hydrophilic Interactions; Hydroxymethylglutaryl-CoA Reductase Inhibitors /adverse effects /chemistry /pharmacokinetics; Tissue Distribution AccessionNumber 12012021294 Date bibliographic record published 27/09/2012 Date abstract record published 09/04/2013 Record Status (...) Is statin-associated cognitive impairment clinically relevant? A narrative review and clinical recommendations Is statin-associated cognitive impairment clinically relevant? A narrative review and clinical recommendations Is statin-associated cognitive impairment clinically relevant? A narrative review and clinical recommendations Rojas-Fernandez CH, Cameron JC CRD summary This review concluded that there was insufficient evidence to make any confident conclusions about whether statins can

2012 DARE.