Latest & greatest articles for thyroid

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Top results for thyroid

361. Effects of thyroid hormone suppression therapy on adverse clinical outcomes in thyroid cancer

Effects of thyroid hormone suppression therapy on adverse clinical outcomes in thyroid cancer Effects of thyroid hormone suppression therapy on adverse clinical outcomes in thyroid cancer Effects of thyroid hormone suppression therapy on adverse clinical outcomes in thyroid cancer McGriff N J, Csako G, Gourgiotis L, Guthrie L C, Pucino F, Sarlis N J Authors' objectives To evaluate the effect of thyroid hormone suppression therapy (THST) on the clinical outcomes of papillary and/or follicular (...) well-differentiated thyroid cancer (ThyrCa). Searching MEDLINE and EMBASE were searched using the search terms listed in the report. Manual searches of literature (1937 to 2000) were also performed. There were no language restrictions, but only published studies were eligible for inclusion. Study selection Study designs of evaluations included in the review The review did not state a priori inclusion criteria for study design. The included studies were described as case series, registry

2002 DARE.

362. Effectiveness of thyroid hormone suppressive therapy in benign solitary thyroid nodules: a meta-analysis

Effectiveness of thyroid hormone suppressive therapy in benign solitary thyroid nodules: a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2002 DARE.

363. Pharmacotherapy for thyroid nodules: a systematic review and meta-analysis

Pharmacotherapy for thyroid nodules: a systematic review and meta-analysis Pharmacotherapy for thyroid nodules: a systematic review and meta-analysis Pharmacotherapy for thyroid nodules: a systematic review and meta-analysis Richter B, Neises G, Clar C Authors' objectives To determine the effect of thyrotropin (thyroid-stimulating hormone, TSH) in the suppression of thyroid hormone in patients with thyroid nodule growth. Searching The Cochrane Controlled Trial Register in the Cochrane Library (...) (Issue 4, 2001) and MEDLINE (1966 to 10, 2001) were searched; the search terms were provided. In addition, the authors checked the reference lists of eligible studies and reviewed editorials, narrative reviews and book chapters for other eligible trials. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) were eligible for inclusion. Specific interventions included in the review Studies that assessed thyroid hormone versus placebo or no therapy

2002 DARE.

364. The value of frozen section examinations in determining the extent of thyroid surgery in patients with indeterminate fine-needle aspiration cytology

The value of frozen section examinations in determining the extent of thyroid surgery in patients with indeterminate fine-needle aspiration cytology The value of frozen section examinations in determining the extent of thyroid surgery in patients with indeterminate fine-needle aspiration cytology The value of frozen section examinations in determining the extent of thyroid surgery in patients with indeterminate fine-needle aspiration cytology Roach J C, Heller K S, Dubner S, Sznyter L A Record (...) Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of intraoperative frozen section examination (FSE) to establish a diagnosis of thyroid cancer in patients undergoing thyroidectomy for nodules with indeterminate cytological results

2002 NHS Economic Evaluation Database.

365. Role of fine-needle aspiration biopsy and frozen-section evaluation in the surgical management of thyroid nodules Full Text available with Trip Pro

Role of fine-needle aspiration biopsy and frozen-section evaluation in the surgical management of thyroid nodules Role of fine-needle aspiration biopsy and frozen-section evaluation in the surgical management of thyroid nodules Role of fine-needle aspiration biopsy and frozen-section evaluation in the surgical management of thyroid nodules Caraci P, Aversa S, Mussa A, Pancani G, Ondolo C, Conticello S Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of intraoperative frozen section (FS) and fine-needle aspiration biopsy (FNAB) for the evaluation of thyroid nodules that require surgical treatment. Type of intervention Diagnosis. Economic study type Cost-effectiveness analysis. Study population The study population

2002 NHS Economic Evaluation Database.

366. Microchimerism of presumed fetal origin in thyroid specimens from women: a case-control study. (Abstract)

Microchimerism of presumed fetal origin in thyroid specimens from women: a case-control study. Some so-called autoimmune diseases in women might be alloimmune and represent a chronic graft-versus-host response attributable to transplacentally acquired fetal cells. Thyroid disease is more common in women than men, and post partum exacerbation of thyroiditis is common. Our aim was to investigate whether there is an association between fetal cell microchimerism and thyroid disease (...) in women.Surgical specimens were obtained from 29 women who underwent thyroidectomy for various thyroid disorders. Control specimens were taken from clinically and histologically normal thyroids obtained at necropsy from eight women who died from unrelated conditions. Medical records and pregnancy histories were reviewed. Fluorescence in-situ hybridisation analysis was done with probes specific for X and Y chromosomes. Slides were examined with a fluorescence microscope to detect the presence of male cells

2001 Lancet

367. 15 years after Chernobyl: new evidence of thyroid cancer. (Abstract)

15 years after Chernobyl: new evidence of thyroid cancer. The Chernobyl nuclear power plant accident happened on April 26, 1986. We investigated the cause of the striking increase in frequency of thyroid cancer in children who lived within a 150 km radius of Chernobyl and who were born before and after the accident. No thyroid cancer was seen in 9472 children born in 1987-89, whereas one and 31 thyroid cancers were recorded in 2409 children born April 27, 1986, to Dec 31, 1986, and 9720 born (...) Jan 1, 1983, to April 26, 1986, respectively. Short-lived radioactive fallout caused by the Chernobyl accident probably induced thyroid cancer in children living near Chernobyl.

2001 Lancet

368. Thyroxine treatment in patients with symptoms of hypothyroidism but thyroid function tests within the reference range: randomised double blind placebo controlled crossover trial. Full Text available with Trip Pro

Thyroxine treatment in patients with symptoms of hypothyroidism but thyroid function tests within the reference range: randomised double blind placebo controlled crossover trial. To determine whether thyroxine treatment is effective in patients with symptoms of hypothyroidism but with thyroid function tests within the reference range, and to investigate the effect of thyroxine treatment on psychological and physical wellbeing in healthy participants.Randomised double blind placebo controlled (...) crossover trial.Outpatient clinic in a general hospital.25 patients with symptoms of hypothyroidism who had thyroid function tests within the reference range, and 19 controls.PARTICIPANTS were given thyroxine 100 microgram or placebo to take once a day for 12 weeks. Washout period was six weeks. They were then given the other to take once a day for 12 weeks. All participants were assessed physiologically and psychologically at baseline and on completion of each phase.Thyroid function tests, measures

2001 BMJ Controlled trial quality: predicted high

369. Diagnostic accuracy of 18F-fluorodeoxyglucose positron emission tomography in the follow-up of papillary or follicular thyroid cancer Full Text available with Trip Pro

Diagnostic accuracy of 18F-fluorodeoxyglucose positron emission tomography in the follow-up of papillary or follicular thyroid cancer Diagnostic accuracy of 18F-fluorodeoxyglucose positron emission tomography in the follow-up of papillary or follicular thyroid cancer Diagnostic accuracy of 18F-fluorodeoxyglucose positron emission tomography in the follow-up of papillary or follicular thyroid cancer Hooft L, Hoekstra O S, Deville W, Lips P, Teule G J, Boers M, van Tulder M W Authors' objectives (...) To determine the diagnostic accuracy of positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) in patients suspected of recurrent papillary or follicular thyroid carcinoma. Searching MEDLINE, EMBASE and Cancerlit were searched up to October 2000 for studies reported in any language. A specifically designed search strategy for diagnostic accuracy studies was combined with a specific search for PET, FDG and thyroid cancer. Further details of the searches were provided in the review

2001 DARE.

370. Cost-effectiveness of prenatal screening for postpartum thyroiditis Full Text available with Trip Pro

Cost-effectiveness of prenatal screening for postpartum thyroiditis Cost-effectiveness of prenatal screening for postpartum thyroiditis Cost-effectiveness of prenatal screening for postpartum thyroiditis Bonds D E, Freedberg K A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability (...) of the study and the conclusions drawn. Health technology Screening pregnant women for the thyroid peroxidase (TPO) antibody. This was compared with the current strategy of no screening, or an alternative strategy of a thyroid-stimulating hormone (TSH) test 6 weeks' postpartum. Type of intervention Screening. Economic study type Cost-utility analysis. Study population The study population comprised hypothetical cohorts of 1,000 pregnant women with uncomplicated pregnancies and 1,000 pregnant women

2001 NHS Economic Evaluation Database.

371. Randomized prospective evaluation of frozen-section analysis for follicular neoplasms of the thyroid

Randomized prospective evaluation of frozen-section analysis for follicular neoplasms of the thyroid Randomized prospective evaluation of frozen-section analysis for follicular neoplasms of the thyroid Randomized prospective evaluation of frozen-section analysis for follicular neoplasms of the thyroid Udelsman R, Westra W H, Donovan P I, Sohn T A, Cameron J L Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of frozen-section analysis to establish a precise diagnosis of malignancy on patients with a dominant thyroid nodule, which was demonstrated by fine-needle aspiration (FNA) to be a follicular or Hurthle cell neoplasm of the thyroid. Patients had thyroid lobectomy and isthmusectomy. A surgeon and a pathologist

2001 NHS Economic Evaluation Database.

372. Thyroid hormone for preventing of neurodevelopmental impairment in preterm infants. Full Text available with Trip Pro

Thyroid hormone for preventing of neurodevelopmental impairment in preterm infants. Observational studies have shown an association between transiently low thyroid hormone levels in preterm infants in the first weeks of life (transient hypothyroxemia) and an abnormal neurodevelopmental outcome. Thyroid hormone therapy might prevent this morbidity.To assess whether thyroid hormone therapy in preterm infants without congenital hypothyroidism results in clinically important changes in neonatal (...) and long term outcomes in terms of both benefits and harms.The standard search strategy of the Neonatal Review Group was used. This included searches of the Oxford Database of Perinatal Trials, Cochrane Controlled Trials Register, MEDLINE, previous reviews including cross references, abstracts, conferences, symposia proceedings, expert informants and journal handsearching in the English language.All trials using random or quasi-random patient allocation, in which thyroid hormone therapy (either

2000 Cochrane

373. Ablation of the thyroid remnant and I-131 dose in differentiated thyroid cancer

Ablation of the thyroid remnant and I-131 dose in differentiated thyroid cancer Ablation of the thyroid remnant and I-131 dose in differentiated thyroid cancer Ablation of the thyroid remnant and I-131 dose in differentiated thyroid cancer Doi S A, Woodhouse N J Authors' objectives To compare the efficacy of remnant ablation following a single low dose versus a single high dose of iodine-131 (I-131) in patients with differentiated thyroid cancer, and to determine whether or not the extent (...) in the review Studies of patients who had received surgery for differentiated thyroid cancer were eligible for inclusion in the review. Patients not eligible for inclusion were: patients with medullary, anaplastic or poorly differentiated carcinomas who were not given radioiodine; patients who presented with distant metastases; and patients who received their first dose of I-131 more than 12 months after surgery. The studies included patients who had received total, near-total and sub-total thyroidectomy

2000 DARE.

374. Effect of thyroxine therapy on serum lipoproteins in patients with mild thyroid failure: a quantitative review of the literature Full Text available with Trip Pro

Effect of thyroxine therapy on serum lipoproteins in patients with mild thyroid failure: a quantitative review of the literature Effect of thyroxine therapy on serum lipoproteins in patients with mild thyroid failure: a quantitative review of the literature Effect of thyroxine therapy on serum lipoproteins in patients with mild thyroid failure: a quantitative review of the literature Danese M D, Ladenson P W, Meinert C L, Powe N R Authors' objectives To estimate the expected change in serum (...) lipoprotein concentrations after treatment with hydroxine therapy (T4) in patients with mild thyroid failure, i.e. subclinical hypothyroidism. Searching The authors searched MEDLINE from 1966 to May 1999 using the textwords 'thyroid disease' and 'cholesterol'. Additional published and unpublished material was located by examining the reference lists of retrieved articles, and contacting their authors. Study selection Study designs of evaluations included in the review RCTs and prospective evaluations

2000 DARE.

375. Assessing the effects of thyroid suppression on benign solitary thyroid nodules: a model for using quantitative research synthesis

Assessing the effects of thyroid suppression on benign solitary thyroid nodules: a model for using quantitative research synthesis Assessing the effects of thyroid suppression on benign solitary thyroid nodules: a model for using quantitative research synthesis Assessing the effects of thyroid suppression on benign solitary thyroid nodules: a model for using quantitative research synthesis Csako G, Byrd D, Wesley R A, Sarlis N J, Skarulis M C, Nieman L K, Pucino F Authors' objectives (...) To evaluate and develop standards of care for levothyroxine (L-T4) suppression therapy in patients with benign solitary thyroid nodules. Searching A search of MEDLINE, and a manual search of the literature, were performed from 1950 to 1998 using the MeSH 'levothyroxine' and 'thyroid nodule'. English and non-English language articles were reviewed. Study selection Study designs of evaluations included in the review All study designs were eligible for inclusion in the review. Case reports, open-label cohort

2000 DARE.

376. [Evaluation of the Ultracision ultrasonic dissector in thyroid surgery: a prospective randomized study]

[Evaluation of the Ultracision ultrasonic dissector in thyroid surgery: a prospective randomized study] Evaluation de l'utilisation du dissecteur ultrasonique Ultracision en chirurgie thyroidienne: etude prospective randomisee [Evaluation of the Ultracision ultrasonic dissector in thyroid surgery: a prospective randomized study] Evaluation de l'utilisation du dissecteur ultrasonique Ultracision en chirurgie thyroidienne: etude prospective randomisee [Evaluation of the Ultracision ultrasonic (...) dissector in thyroid surgery: a prospective randomized study] Meurisse M, Defechereux T, Maweja S, Degauque C, Vandelaer M, Hamoir E Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of an ultrasonic hook (HS 002, Ultracision

2000 NHS Economic Evaluation Database.

377. Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis. (Abstract)

Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis. Multiple sclerosis results from T-cell-dependent inflammatory demyelination of the central nervous system. Our objective was long-term suppression of inflammation with short-term monoclonal antibody treatment.We depleted 95% of circulating lymphocytes in 27 patients with multiple sclerosis by means of a 5-day pulse of the humanised anti-CD52 monoclonal antibody, Campath-1H. Clinical and haematological (...) mitogen-induced proliferation and interferon gamma secretion in vitro.Campath-1H causes the immune response to change from the Th1 phenotype, suppressing multiple sclerosis disease activity, but permitting the generation of antibody-mediated thyroid autoimmunity.

1999 Lancet Controlled trial quality: uncertain

378. Evaluation of solitary thyroid nodules in a community practice: a managed care approach

Evaluation of solitary thyroid nodules in a community practice: a managed care approach Evaluation of solitary thyroid nodules in a community practice: a managed care approach Evaluation of solitary thyroid nodules in a community practice: a managed care approach Gossain V V, Charnas J, Carella M J, Rovner D R, Calaca W D Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods (...) , the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Fine-needle aspiration biopsy or radioisotope and ultrasound scan in the initial evaluation of solitary thyroid nodules. Type of intervention Diagnosis. Economic study type Cost-effectiveness analysis. Study population Patients assigned to thyroid aspiration. Setting Hospital. The economic study was carried out in the USA. Dates to which data relate

1998 NHS Economic Evaluation Database.

379. Clinical guideline - part 2. Screening for thyroid disease: an update

Clinical guideline - part 2. Screening for thyroid disease: an update Clinical guideline - part 2. Screening for thyroid disease: an update Clinical guideline - part 2. Screening for thyroid disease: an update Helfand M, Redfern C C Authors' objectives To review information on the benefits of screening with a thyroid-stimulating hormone (TSH) test for thyroid dysfunction in asymptomatic patients seeking primary care for other reasons. A subsidiary aim was to evaluate the efficacy of treatment (...) for subclinical thyroid dysfunction. Searching The authors reviewed the original literature from 1989 to 1996 to identify articles that were not included in the original College background paper (Helfand & Crapo, 1990; see Other Publications of Related Interest). In a MEDLINE search, the MeSH terms "thyroid function tests" and "thyroid diseases" were combined with the term "mass screening" and the textwords "screening" or "case finding". A separate MEDLINE search (1970 to 1996) was conducted for controlled

1998 DARE.

380. Nausea and vomiting following thyroid and parathyroid surgery

Nausea and vomiting following thyroid and parathyroid surgery Nausea and vomiting following thyroid and parathyroid surgery Nausea and vomiting following thyroid and parathyroid surgery Sonner J M, Hynson J M, Clark O, Katz J A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability (...) of the study and the conclusions drawn. Health technology Using propofol versus isoflurane for maintenance of anaesthesia duringthyroid or parathyroid surgery. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population ASA physical status I and II, nonpregnant patients aged 18 years and older, undergoing thyroid and parathyroid procedures. Setting Hospital. The economic study was carried out in California, USA. Dates to which data relate The dates of effectiveness

1997 NHS Economic Evaluation Database.