Latest & greatest articles for traumatic brain injury

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Top results for traumatic brain injury

161. The use of hypothermia as a treatment for traumatic brain injury

stated that use of hypothermia treatment should be further investigated, particularly with a focus on time from injury to ideal cooling, cooling temperatures, duration of cooling and specific populations who may benefit (particularly as it appeared that there was no benefit of hypothermia for patients with low intracranial pressure). Funding None stated. Bibliographic details Rupich K. The use of hypothermia as a treatment for traumatic brain injury. Journal of Neuroscience Nursing 2009; 41(3): 159 (...) The use of hypothermia as a treatment for traumatic brain injury The use of hypothermia as a treatment for traumatic brain injury The use of hypothermia as a treatment for traumatic brain injury Rupich K CRD summary This review evaluated hypothermia to treat traumatic brain injuries and concluded that there may be benefits of hypothermia treatment for some patients with severe traumatic head injuries. Insufficient information was presented about the conduct of the review, quality

2009 DARE.

162. Pre-hospital tracheal intubation in patients with traumatic brain injury: systematic review of current evidence

Pre-hospital tracheal intubation in patients with traumatic brain injury: systematic review of current evidence Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

163. Approaches to vocational rehabilitation after traumatic brain injury: a review of the evidence

Approaches to vocational rehabilitation after traumatic brain injury: a review of the evidence Approaches to vocational rehabilitation after traumatic brain injury: a review of the evidence Approaches to vocational rehabilitation after traumatic brain injury: a review of the evidence Fadyl JK, McPherson KM CRD summary The authors concluded that there was little clear evidence to suggest the best practice approach to vocational rehabilitation in people with traumatic brain injury. Although (...) there were some limitations in reporting of the review, the authors’ conclusions appeared to reflect the limited evidence from a small number of flawed studies. Authors' objectives To evaluate the effectiveness of different approaches to vocational rehabilitation for people after traumatic brain injury. Searching MEDLINE, PsycINFO, CINAHL, AMED, Health and Psychosocial Instruments, EBM databases and Web of Science were searched for studies published in English between 1999 and July 2007. Search terms

2009 DARE.

164. Direct brain tissue oxygen monitoring for traumatic brain injury

Direct brain tissue oxygen monitoring for traumatic brain injury Direct brain tissue oxygen monitoring for traumatic brain injury Direct brain tissue oxygen monitoring for traumatic brain injury Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Report may be purchased from . Citation Direct brain tissue oxygen monitoring for traumatic brain injury . Lansdale: HAYES, Inc (...) .. 2009 Authors' objectives Direct brain tissue oxygen monitoring is used in conjunction with other monitoring modalities to better detect evolving brain injury and thereby avoid secondary brain insults before they cause irreversible damage. Direct brain tissue oxygen monitoring is accomplished by placing a small, oxygen-sensitive catheter directly into the brain tissue. The probe measures the partial pressure of oxygen in the interstitial brain tissue, which is reflective of the balance between

2009 Health Technology Assessment (HTA) Database.

165. Visual problems in traumatic brain injury

Visual problems in traumatic brain injury Visual problems in traumatic brain injury Visual problems in traumatic brain injury Adams E Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Adams E. Visual problems in traumatic brain injury. Boston: VA Technology Assessment Program (VATAP). 2009 Authors' conclusions Mild TBI Overall, the findings (...) from this qualitative systematic review provide moderately suggestive evidence for a range of vision sequelae primarily in the acute stages of mild TBI in younger clinically-based adult populations. The evidence is limited by small sample size and heterogeneity in the selection of cases and controls, injury severity criteria and outcome measures. In the acute stages following mild TBI, photosensitivity is a common complaint particularly in the Veteran population. The evidence suggests that while

2009 Health Technology Assessment (HTA) Database.

166. The economic impact of S-100B as a pre-head CT screening test on emergency department management of adult patients with mild traumatic brain injury

The economic impact of S-100B as a pre-head CT screening test on emergency department management of adult patients with mild traumatic brain injury The economic impact of S-100B as a pre-head CT screening test on emergency department management of adult patients with mild traumatic brain injury The economic impact of S-100B as a pre-head CT screening test on emergency department management of adult patients with mild traumatic brain injury Ruan S, Noyes K, Bazarian JJ Record Status (...) This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study estimated the cost reduction associated with serum-100B testing to determine whether a computed tomography (CT) scan was required for adults with an isolated mild traumatic brain injury. The authors

2009 NHS Economic Evaluation Database.

167. Branched-chain amino acids may improve recovery from a vegetative or minimally conscious state in patients with traumatic brain injury: a pilot study (Abstract)

Branched-chain amino acids may improve recovery from a vegetative or minimally conscious state in patients with traumatic brain injury: a pilot study To investigate whether supplementation with branched-chain amino acids (BCAAs) may improve recovery of patients with a posttraumatic vegetative or minimally conscious state.Patients were randomly assigned to 15 days of intravenous BCAA supplementation (n=22; 19.6g/d) or an isonitrogenous placebo (n=19).Tertiary care rehabilitation setting.Patients (...) (N=41; 29 men, 12 women; mean age, 49.5+/-21 y) with a posttraumatic vegetative or minimally conscious state, 47+/-24 days after the index traumatic event.Supplementation with BCAAs.Disability Rating Scale (DRS) as log(10)DRS.Fifteen days after admission to the rehabilitation department, the log(10)DRS score improved significantly only in patients who had received BCAAs (log(10)DRS score, 1.365+/-0.08 to 1.294+/-0.05; P<.001), while the log(10)DRS score in the placebo recipients remained

2008 EvidenceUpdates Controlled trial quality: uncertain

168. Neuroendocrine disorders after traumatic brain injury (Abstract)

Neuroendocrine disorders after traumatic brain injury Traumatic brain injury (TBI) is the most common cause of death and disability in young adults living in industrialised countries, in which 180-250 persons per 100 000 per year die or are hospitalised as a result. Neuroendocrine derangements after TBI have received increasing recognition in recent years because of their potential contribution to morbidity, and possibly mortality, after trauma. Marked changes of the hypothalamo-pituitary axis (...) . There remains a high frequency of hypothalamic-pituitary hormone deficiencies among long-term survivors of TBI, with approximately 25% patients showing one or more pituitary hormone deficiencies. This is a higher frequency than previously thought and suggests that most cases of post-traumatic hypopituitarism (PTHP) remain undiagnosed and untreated. PTHP has been associated with adverse outcome both in the acute and chronic phases after injury. These data underscore the need for the identification

2008 EvidenceUpdates

169. Modest cooling therapies (35 degrees C to 37.5 degrees C) for traumatic brain injury. (Abstract)

Modest cooling therapies (35 degrees C to 37.5 degrees C) for traumatic brain injury. A recent retrospective study suggested that after traumatic brain injury, patients with a raised body temperature have an unfavourable outcome compared to patients that have a normal body temperature.To assess the effects of modest cooling therapies (defined as any drug or physical therapy aimed at maintaining body temperature between 35 degrees C and 37.5 degrees C) when applied to patients in the first week (...) after traumatic brain injury.We searched the Cochrane Injuries Group's Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2007, Issue 3), MEDLINE (1950 to 2008), EMBASE (1980 to 2008), the National Research Register, Zetoc and the Current Controlled Trials MetaRegister of controlled trials. We also contacted investigators, pharmaceutical companies and the manufacturers of cooling equipment. The searches were conducted August to September 2007

2008 Cochrane

170. Saline or Albumin for Fluid Resuscitation in Patients with Traumatic Brain Injury

Saline or Albumin for Fluid Resuscitation in Patients with Traumatic Brain Injury PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2008 PedsCCM Evidence-Based Journal Club

171. Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients. Full Text available with Trip Pro

Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients. To develop and validate practical prognostic models for death at 14 days and for death or severe disability six months after traumatic brain injury.Multivariable logistic regression to select variables that were independently associated with two patient outcomes. Two models designed: "basic" model (demographic and clinical variables only) and "CT" model (basic model plus (...) results of computed tomography). The models were subsequently developed for high and low-middle income countries separately.Medical Research Council (MRC) CRASH Trial.10,008 patients with traumatic brain injury. Models externally validated in a cohort of 8509.The basic model included four predictors: age, Glasgow coma scale, pupil reactivity, and the presence of major extracranial injury. The CT model also included the presence of petechial haemorrhages, obliteration of the third ventricle or basal

2008 BMJ

172. Treatment efficacy of social communication skills training after traumatic brain injury: a randomized treatment and deferred treatment controlled trial. (Abstract)

Treatment efficacy of social communication skills training after traumatic brain injury: a randomized treatment and deferred treatment controlled trial. To evaluate the efficacy of a replicable group treatment program to improve social communication skills after traumatic brain injury (TBI).Randomized treatment and deferred treatment controlled trial, with follow-up at 3, 6, and 9 months post-treatment.Community.Volunteer sample of 52 people with TBI who were at least 1 year postinjury, who

2008 EvidenceUpdates Controlled trial quality: uncertain

173. Mild traumatic brain injury in U.S. Soldiers returning from Iraq. Full Text available with Trip Pro

Mild traumatic brain injury in U.S. Soldiers returning from Iraq. An important medical concern of the Iraq war is the potential long-term effect of mild traumatic brain injury, or concussion, particularly from blast explosions. However, the epidemiology of combat-related mild traumatic brain injury is poorly understood.We surveyed 2525 U.S. Army infantry soldiers 3 to 4 months after their return from a year-long deployment to Iraq. Validated clinical instruments were used to compare soldiers (...) reporting mild traumatic brain injury, defined as an injury with loss of consciousness or altered mental status (e.g., dazed or confused), with soldiers who reported other injuries.Of 2525 soldiers, 124 (4.9%) reported injuries with loss of consciousness, 260 (10.3%) reported injuries with altered mental status, and 435 (17.2%) reported other injuries during deployment. Of those reporting loss of consciousness, 43.9% met criteria for post-traumatic stress disorder (PTSD), as compared with 27.3% of those

2008 NEJM

174. Hypothermia therapy after traumatic brain injury in children. Full Text available with Trip Pro

Hypothermia therapy after traumatic brain injury in children. Hypothermia therapy improves survival and the neurologic outcome in animal models of traumatic brain injury. However, the effect of hypothermia therapy on the neurologic outcome and mortality among children who have severe traumatic brain injury is unknown.In a multicenter, international trial, we randomly assigned children with severe traumatic brain injury to either hypothermia therapy (32.5 degrees C for 24 hours) initiated within (...) during the rewarming period than in the normothermia group. Lengths of stay in the intensive care unit and in the hospital and other adverse events were similar in the two groups.In children with severe traumatic brain injury, hypothermia therapy that is initiated within 8 hours after injury and continued for 24 hours does not improve the neurologic outcome and may increase mortality. (Current Controlled Trials number, ISRCTN77393684 [controlled-trials.com].).Copyright 2008 Massachusetts Medical

2008 NEJM Controlled trial quality: predicted high

175. Intervention for executive functions after traumatic brain injury: a systematic review, meta-analysis and clinical recommendations

Intervention for executive functions after traumatic brain injury: a systematic review, meta-analysis and clinical recommendations Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2008 DARE.

176. The effectiveness of donepezil for cognitive rehabilitation after traumatic brain injury: a systematic review

The effectiveness of donepezil for cognitive rehabilitation after traumatic brain injury: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2008 DARE.

177. Hypothermia treatment for traumatic brain injury: a systematic review and meta-analysis Full Text available with Trip Pro

Hypothermia treatment for traumatic brain injury: a systematic review and meta-analysis Hypothermia treatment for traumatic brain injury: a systematic review and meta-analysis Hypothermia treatment for traumatic brain injury: a systematic review and meta-analysis Peterson K, Carson S, Carney N CRD summary The authors concluded that in specific circumstances hypothermia may reduce mortality and increase the likelihood of a favourable neurological outcome in adults with traumatic brain injury (...) : more research is needed. Although the review was well conducted in many respects, these conclusions may need to be regarded cautiously, given the rather limited search and the questionable quality of the primary studies. Authors' objectives To evaluate the safety and effectiveness of hypothermia for treating adults with traumatic brain injury (TBI). Searching Four previously published systematic reviews were hand searched for relevant studies (see Other publications of related interest). Search

2008 DARE.

178. Cognitive rehabilitation for traumatic brain injury in adults

Cognitive rehabilitation for traumatic brain injury in adults Cognitive rehabilitation for traumatic brain injury in adults Cognitive rehabilitation for traumatic brain injury in adults BlueCross BlueShield Association Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation BlueCross BlueShield Association. Cognitive rehabilitation for traumatic brain injury in adults (...) rehabilitation does not show strong evidence for efficacy in the treatment of traumatic brain injury. Many of the clinical trials of specific cognitive rehabilitation interventions evaluated cognitive tests rather than health outcomes. Demonstration of the effectiveness of cognitive rehabilitation, either as an integrated holistic program, or as a separable component that treats a specific cognitive defect, requires prospective randomized designs that employ validated measures of health outcomes. Based

2008 Health Technology Assessment (HTA) Database.

179. Routine serial computed tomographic scans in mild traumatic brain injury: when are they cost-effective? Full Text available with Trip Pro

interventions were an expectant strategy, which was waiting for clinical deterioration before repeating the diagnostic study, and a more active strategy, which was routine serial computed tomography (CT). The study involved patients with mild traumatic brain injury (TBI) who, on admission, demonstrated at least one intracranial abnormality on their CT scan, that revealed an intracranial lesion, which did not require immediate surgery. Location/setting USA/emergency department. Methods Analytical approach (...) Routine serial computed tomographic scans in mild traumatic brain injury: when are they cost-effective? Routine serial computed tomographic scans in mild traumatic brain injury: when are they cost-effective? Routine serial computed tomographic scans in mild traumatic brain injury: when are they cost-effective? Stein S C, Fabbri A, Servadei F Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief

2008 NHS Economic Evaluation Database.

180. Serial casting versus positioning for the treatment of elbow contractures in adults with traumatic brain injury: a randomized controlled trial Full Text available with Trip Pro

Serial casting versus positioning for the treatment of elbow contractures in adults with traumatic brain injury: a randomized controlled trial To compare the effects of serial casting with positioning for 1 hour per day for the treatment of elbow flexion contracture in adults with traumatic brain injury.Pragmatic randomized controlled trial with concealed allocation and assessor blinding.Four brain injury rehabilitation units.Twenty-six adults with elbow flexion contracture after traumatic (...) brain injury participating in multidisciplinary inpatient rehabilitation.Subjects were randomized to receive either serial casting or positioning for two weeks. In the subsequent four weeks subjects could be positioned for up to 1 hour/day.Torque-controlled passive elbow extension was measured at baseline, post-intervention (two weeks), post-intervention plus one day, and at follow-up (four weeks post-intervention).All 26 subjects completed the study. Post-intervention, serial casting reduced

2008 EvidenceUpdates Controlled trial quality: predicted high